-
1
-
-
0028108820
-
On the pathogenesis of IDDM
-
Nerup J, Mandrup-Poulsen T, Helqvist S, Andersen HU, Pociot F, Reimers J, Cuartero BG, Karlsen AE, Bjerre U, Lorenzen T: On the pathogenesis of IDDM. Diabetologia 37 (Suppl. 2):S82-S89, 1994
-
(1994)
Diabetologia
, vol.37
, Issue.2 SUPPL.
-
-
Nerup, J.1
Mandrup-Poulsen, T.2
Helqvist, S.3
Andersen, H.U.4
Pociot, F.5
Reimers, J.6
Cuartero, B.G.7
Karlsen, A.E.8
Bjerre, U.9
Lorenzen, T.10
-
2
-
-
0026079608
-
Biochemical and molecular actions of interleukin-1 on pancreatic β-cells
-
Sandler S, Eizirik DL, Svensson C, Strandell E, Welsh M, Welsh N: Biochemical and molecular actions of interleukin-1 on pancreatic β-cells. Autoimmunity 10:241-253, 1991
-
(1991)
Autoimmunity
, vol.10
, pp. 241-253
-
-
Sandler, S.1
Eizirik, D.L.2
Svensson, C.3
Strandell, E.4
Welsh, M.5
Welsh, N.6
-
3
-
-
0026683354
-
Does nitric oxide mediate autoimmune destruction of β-cells? Possible therapeutic interventions in IDDM
-
Corbett JA, McDaniel ML: Does nitric oxide mediate autoimmune destruction of β-cells? Possible therapeutic interventions in IDDM. Diabetes 41:897-903, 1992
-
(1992)
Diabetes
, vol.41
, pp. 897-903
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
4
-
-
0026589802
-
Repetitive in vivo treatment with human recombinant interleukin-1β modifies beta-cell function in normal rats
-
Wogensen L, Reimers J, Nerup J, Kolb-Bachofen V, Kroncke K-D, Almdal T, Mandrup, Poulsen T: Repetitive in vivo treatment with human recombinant interleukin-1β modifies beta-cell function in normal rats. Diabetologia 35:331-339, 1992
-
(1992)
Diabetologia
, vol.35
, pp. 331-339
-
-
Wogensen, L.1
Reimers, J.2
Nerup, J.3
Kolb-Bachofen, V.4
Kroncke, K.-D.5
Almdal, T.6
Mandrup7
Poulsen, T.8
-
5
-
-
0025817159
-
Cytokine gene expression in the islets of the diabetic Biobreeding/Worcester rat
-
Jiang Z, Woda BA: Cytokine gene expression in the islets of the diabetic Biobreeding/Worcester rat. J Immunol 146:2990-2994, 1991
-
(1991)
J Immunol
, vol.146
, pp. 2990-2994
-
-
Jiang, Z.1
Woda, B.A.2
-
6
-
-
0025230418
-
Genes encoding tumor necrosis factor α and granzyme A are expressed during development of autoimmune diabetes
-
Held W, MacDonald HR, Weissman IL, Hess MW, Mueller C: Genes encoding tumor necrosis factor α and granzyme A are expressed during development of autoimmune diabetes. Proc Natl Acad USA 87:2239-2243, 1990
-
(1990)
Proc Natl Acad USA
, vol.87
, pp. 2239-2243
-
-
Held, W.1
MacDonald, H.R.2
Weissman, I.L.3
Hess, M.W.4
Mueller, C.5
-
7
-
-
0002694711
-
IL-1 receptor antagonist delays spontaneous autoimmune diabetes in BB rats
-
Dayer-Metroz M-D, Duhamel D, Rufer N, Izui S, Carmichals D, Wolheim CB, Thompson RC, Dayer J-M: IL-1 receptor antagonist delays spontaneous autoimmune diabetes in BB rats (Abstract). Eur J Clin Invest 22:A50, 1992
-
(1992)
Eur J Clin Invest
, vol.22
-
-
Dayer-Metroz, M.-D.1
Duhamel, D.2
Rufer, N.3
Izui, S.4
Carmichals, D.5
Wolheim, C.B.6
Thompson, R.C.7
Dayer, J.-M.8
-
8
-
-
0028031142
-
Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor
-
Nicoletti F, Di Marco R, Barcellini W, Magro G, Schorlemmer HU, Kurrle R, Lunetta M, Grasso S, Zaccone P, Moroni PL: Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor. Eur J Immunol 24:1843-1847, 1994
-
(1994)
Eur J Immunol
, vol.24
, pp. 1843-1847
-
-
Nicoletti, F.1
Di Marco, R.2
Barcellini, W.3
Magro, G.4
Schorlemmer, H.U.5
Kurrle, R.6
Lunetta, M.7
Grasso, S.8
Zaccone, P.9
Moroni, P.L.10
-
9
-
-
0029082331
-
Cloning and expression of cytokine inducible nitric oxide synthase cDNA from rat islets of Langerhans
-
Karlsen AE, Andersen HU, Vissing H, Larsen PM, Fey SJ, Cuartero BG, Madsen OD, Petersen JS, Mortensen SB, Mandrup-Poulsen T, Boel E, Nerup J: Cloning and expression of cytokine inducible nitric oxide synthase cDNA from rat islets of Langerhans. Diabetes 44:753-758, 1995
-
(1995)
Diabetes
, vol.44
, pp. 753-758
-
-
Karlsen, A.E.1
Andersen, H.U.2
Vissing, H.3
Larsen, P.M.4
Fey, S.J.5
Cuartero, B.G.6
Madsen, O.D.7
Petersen, J.S.8
Mortensen, S.B.9
Mandrup-Poulsen, T.10
Boel, E.11
Nerup, J.12
-
10
-
-
0025685395
-
Inhibition of insulin secretion by interleukin-1β and tumor necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism
-
Southern C, Schulster D, Green IC: Inhibition of insulin secretion by interleukin-1β and tumor necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett 276:42-44, 1990
-
(1990)
FEBS Lett
, vol.276
, pp. 42-44
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
11
-
-
0025833992
-
Interleukin-1β- Induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
-
Welsh N, Eizirik DL, Bendtzen K, Sandler S: Interleukin-1β- induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology 129:3167-3173, 1991
-
(1991)
Endocrinology
, vol.129
, pp. 3167-3173
-
-
Welsh, N.1
Eizirik, D.L.2
Bendtzen, K.3
Sandler, S.4
-
13
-
-
0026641944
-
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction
-
Corbett JA, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR, Williamson JR, McDaniel ML: Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41:552-056, 1992
-
(1992)
Diabetes
, vol.41
, pp. 552-1056
-
-
Corbett, J.A.1
Tilton, R.G.2
Chang, K.3
Hasan, K.S.4
Ido, Y.5
Wang, J.L.6
Sweetland, M.A.7
Lancaster, J.R.8
Williamson, J.R.9
McDaniel, M.L.10
-
14
-
-
0027932846
-
Interleukin-1β induces diabetes and fever in normal rats by nitric oxide via induction of different nitric oxide synthases
-
Reimers JI, Bjerre U, Mandrup-Poulsen T, Nerup J: Interleukin-1β induces diabetes and fever in normal rats by nitric oxide via induction of different nitric oxide synthases. Cytokine 6:512-520, 1994
-
(1994)
Cytokine
, vol.6
, pp. 512-520
-
-
Reimers, J.I.1
Bjerre, U.2
Mandrup-Poulsen, T.3
Nerup, J.4
-
15
-
-
0028362968
-
Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans
-
Andersen HU, Jørgensen KH, Egeberg J, Mandrup-Poulsen T, Nerup J: Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans. Diabetes 43:770-777, 1994
-
(1994)
Diabetes
, vol.43
, pp. 770-777
-
-
Andersen, H.U.1
Jørgensen, K.H.2
Egeberg, J.3
Mandrup-Poulsen, T.4
Nerup, J.5
-
16
-
-
0024498140
-
Genetically determined differences in newborn rat islet sensitivity to interleukin-1 in vitro: No association with the diabetes prone phenotype in the BB-rat
-
Andersen HU, Mandrup-Poulsen T, Egeberg J, Helqvist S, Nerup J: Genetically determined differences in newborn rat islet sensitivity to interleukin-1 in vitro: no association with the diabetes prone phenotype in the BB-rat. Acta Endocrinol 120:92-98, 1989
-
(1989)
Acta Endocrinol
, vol.120
, pp. 92-98
-
-
Andersen, H.U.1
Mandrup-Poulsen, T.2
Egeberg, J.3
Helqvist, S.4
Nerup, J.5
-
17
-
-
0024514087
-
Cloning and expression of an interleukin-1β precursor and its conversion to interleukin-1β
-
Dalbøge H, Bayne S, Christensen T, Hejnæs K. Cloning and expression of an interleukin-1β precursor and its conversion to interleukin-1β. FEBS Lett 246:89-93, 1989
-
(1989)
FEBS Lett
, vol.246
, pp. 89-93
-
-
Dalbøge, H.1
Bayne, S.2
Christensen, T.3
Hejnæs, K.4
-
18
-
-
0025165198
-
Comparison of biological and immunological activities of human monocyte-derived interleukin 1β and human recombinant interleukin 1β
-
Mølvig J, Sehested Hansen B, Worsaae H, Hejnæs K, Helle M, Dalbøge H, Nerup J: Comparison of biological and immunological activities of human monocyte-derived interleukin 1β and human recombinant interleukin 1β. Scand J Immunol 31:225-235, 1990
-
(1990)
Scand J Immunol
, vol.31
, pp. 225-235
-
-
Mølvig, J.1
Sehested Hansen, B.2
Worsaae, H.3
Hejnæs, K.4
Helle, M.5
Dalbøge, H.6
Nerup, J.7
-
19
-
-
0000126647
-
Isolation of islets from mice and rats
-
Larner J, Pohl SL, Eds. New York, Wiley
-
Brunstedt J, Nielsen JH, Lernmark A, Hagedorn Study Group: Isolation of islets from mice and rats. In Methods in Diabetes Research. Vol 1. Larner J, Pohl SL, Eds. New York, Wiley, 1984, p. 254-288
-
(1984)
Methods in Diabetes Research
, vol.1
, pp. 254-288
-
-
Brunstedt, J.1
Nielsen, J.H.2
Lernmark, A.3
-
21
-
-
0015376786
-
Determination of total serum insulin (IRI) in insulin-treated diabetic patients
-
Heding LG: Determination of total serum insulin (IRI) in insulin-treated diabetic patients. Diabetologia 8:260-266, 1972
-
(1972)
Diabetologia
, vol.8
, pp. 260-266
-
-
Heding, L.G.1
-
22
-
-
0015016041
-
Radioimmunological determination of pancreatic and gut glucagon in plasma
-
Heding LG: Radioimmunological determination of pancreatic and gut glucagon in plasma. Diabetolagia 7:10-19, 1971
-
(1971)
Diabetolagia
, vol.7
, pp. 10-19
-
-
Heding, L.G.1
-
23
-
-
0026046093
-
Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10
-
Karlsen AE, Hagopian WA, Grubin CE, Dube S, Disteche CM, Adler DA, Bärmaier H, Mathewes S, Grant FJ, Foster D, Lernmark Å: Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acid Sci USA 88:8337-8341, 1991
-
(1991)
Proc Natl Acid Sci USA
, vol.88
, pp. 8337-8341
-
-
Karlsen, A.E.1
Hagopian, W.A.2
Grubin, C.E.3
Dube, S.4
Disteche, C.M.5
Adler, D.A.6
Bärmaier, H.7
Mathewes, S.8
Grant, F.J.9
Foster, D.10
Lernmark, Å.11
-
24
-
-
0028603421
-
Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice
-
Petersen JS, Karlsen AE, Markholst H, Worsaae A, Dyrberg T, Michelsen B: Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice. Diabetes 44:1478-1484, 1994
-
(1994)
Diabetes
, vol.44
, pp. 1478-1484
-
-
Petersen, J.S.1
Karlsen, A.E.2
Markholst, H.3
Worsaae, A.4
Dyrberg, T.5
Michelsen, B.6
-
25
-
-
0023550387
-
Islet cytoxicity of interleukin-1: Influence of culture conditions and islet donor characteristics
-
Mandrup-Poulsen T, Spinas GA, Prowse SJ, Hansen BS, Jørgensen DW, Bendtzen K, Nielsen JH, Nerup J: Islet cytoxicity of interleukin-1: influence of culture conditions and islet donor characteristics. Diabetes 36:641-647, 1987
-
(1987)
Diabetes
, vol.36
, pp. 641-647
-
-
Mandrup-Poulsen, T.1
Spinas, G.A.2
Prowse, S.J.3
Hansen, B.S.4
Jørgensen, D.W.5
Bendtzen, K.6
Nielsen, J.H.7
Nerup, J.8
-
26
-
-
0025009733
-
Interleukin-1β depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism
-
Eizirik DL, Welsh M, Strandell E, Welsh N, Sandler S: Interleukin-1β depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism. Endocrinology 127:2290-2297, 1990
-
(1990)
Endocrinology
, vol.127
, pp. 2290-2297
-
-
Eizirik, D.L.1
Welsh, M.2
Strandell, E.3
Welsh, N.4
Sandler, S.5
-
27
-
-
0028049833
-
Major species differences between human and rodents in the susceptibility to pancreatic β-cell injury
-
Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerström C, Andersson A: Major species differences between human and rodents in the susceptibility to pancreatic β-cell injury. Proc Natl Acad Sci USA 91:9253-9256, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9253-9256
-
-
Eizirik, D.L.1
Pipeleers, D.G.2
Ling, Z.3
Welsh, N.4
Hellerström, C.5
Andersson, A.6
-
28
-
-
0028900805
-
Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase
-
Corbett JA, McDaniel ML: Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase. J Exp Med 181:559-568, 1995
-
(1995)
J Exp Med
, vol.181
, pp. 559-568
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
29
-
-
0026529983
-
Nitric-oxide-induced anti-mitogenic effects in high and low responder rat strains
-
Fu Y, Blackenhorn EP: Nitric-oxide-induced anti-mitogenic effects in high and low responder rat strains. J Immunol 148:2217-2222, 1992
-
(1992)
J Immunol
, vol.148
, pp. 2217-2222
-
-
Fu, Y.1
Blackenhorn, E.P.2
-
30
-
-
0024421432
-
Interaction of β-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans
-
Palmer JP, Helqvist S, Spinas GA, Mølvig J, Mandrup-Poulsen T, Andersen HU, Nerup J: Interaction of β-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans. Diabetes 38:1211-1216, 1989
-
(1989)
Diabetes
, vol.38
, pp. 1211-1216
-
-
Palmer, J.P.1
Helqvist, S.2
Spinas, G.A.3
Mølvig, J.4
Mandrup-Poulsen, T.5
Andersen, H.U.6
Nerup, J.7
-
31
-
-
0029670692
-
Interleukin-1β-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine
-
Andersen HU, Mauricio D, Karlsen AE, Mandrup-Poulsen T, Nielsen JH, Nerup J: Interleukin-1β-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine. Eur J Endocrinol 134:251-259, 1996
-
(1996)
Eur J Endocrinol
, vol.134
, pp. 251-259
-
-
Andersen, H.U.1
Mauricio, D.2
Karlsen, A.E.3
Mandrup-Poulsen, T.4
Nielsen, J.H.5
Nerup, J.6
-
32
-
-
0027323713
-
Serum corticosterone, interleukin-1 and tumor necrosis factor in rat experimental endotoxaemia: Comparison between Lewis and Wistar rats
-
Perretti M, Duncan GS, Flower RJ, Peers SH: Serum corticosterone, interleukin-1 and tumor necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar rats. Br J Pharmacol 110:868-874, 1993
-
(1993)
Br J Pharmacol
, vol.110
, pp. 868-874
-
-
Perretti, M.1
Duncan, G.S.2
Flower, R.J.3
Peers, S.H.4
-
33
-
-
0345432605
-
Genetic characterisation and interrelationship of inbred lines of diabetes-prone and not diabetes-prone BB rats
-
Shafrir E, Ed. Smith-Gordon
-
Prins J-B, Herberg L, Bieman MD, van Zutpen BFM: Genetic characterisation and interrelationship of inbred lines of diabetes-prone and not diabetes-prone BB rats. In Frontiers in Diabetes Research: Lessons From Animal Diabetes III. Shafrir E, Ed. Smith-Gordon 1990, p. 19-24
-
(1990)
Frontiers in Diabetes Research: Lessons from Animal Diabetes III
, pp. 19-24
-
-
Prins, J.-B.1
Herberg, L.2
Bieman, M.D.3
Van Zutpen, B.F.M.4
|