Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 6, 2007, Pages 2298-2311

  Nuti, Elisa ^a   Orlandini, Elisabetta ^a   Nencetti, Susanna ^a   Rossello, Armando ^a   Innocenti, Alessio ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase inhibitors; Hydroxamic acid inhibitors; Matrix metalloproteinase inhibitors

Indexed keywords

2 (4 CHLOROBENZYLOXYAMINO) N HYDROXYACETAMIDE; 2 (4 CHLOROBENZYLOXYAMINO) N HYDROXYHEXANAMIDE; 2 (4 CHLOROBENZYLOXYAMINO) N HYDROXYPROPANAMIDE; 2 (BENZYLOXYAMINO) N HYDROXY 3 METHYLPENTANAMIDE; 2 (BENZYLOXYAMINO) N HYDROXYACETAMIDE; 2 (BENZYLOXYAMINO) N HYDROXYHEXANAMIDE; 2 [4 CHLOROBENZYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [ADAMANTYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [BENZYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [BENZYLOXYBENZYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [ETHYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [ISOPROPOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; 2 [N TETRADECYLOXY[(4 METHOXYPHENYL)SULFONYL]AMINO] N HYDROXYACETAMIDE; ACETAZOLAMIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE INHIBITOR; CGS 27023A; DICLOFENAMIDE; ETHOXZOLAMIDE; GELATINASE A; GELATINASE B; HYDROXAMIC ACID DERIVATIVE; INDISULAM; ISOENZYME; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; METHAZOLAMIDE; N HYDROXY 2 [N ISOPROPOXY(4 METHOXYPHENYL)SULFONAMIDO] 3 METHYLBUTANAMIDE; N HYDROXY 2 [N SEC BUTYLOXY(4 METHOXYPHENYL)SULFONAMIDO] 3 METHYLBUTANAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER INVASION; CARCINOGENESIS; CONTROLLED STUDY; CYTOSOL; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; MOUSE; NONHUMAN;

ANIMALS; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CYTOSOL; ENZYME INHIBITORS; HUMANS; HYDROXAMIC ACIDS; ISOENZYMES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MOLECULAR STRUCTURE; MULTIPLE MYELOMA; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS; TUMOR CELLS, CULTURED;

EID: 33847003058     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.01.023     Document Type: Article

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