Magnolol suppresses NF-κB activation and NF-κB regulated gene expression through inhibition of IkappaB kinase activation

Molecular Immunology

Volumn 44, Issue 10, 2007, Pages 2647-2658

  Tse, Anfernee Kai Wing ^a,b   Wan, Chi Keung ^a   Zhu, Guo Yuan ^a   Shen, Xiao Ling ^a   Cheung, Hon Yeung ^a   Yang, Mengsu ^a   Fong, Wang Fun ^b  

^a CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Anti inflammation; IKK; Magnolol; Nuclear factor kappa B

Indexed keywords

DNA; GELATINASE B; GENE PRODUCT; HETERODIMER; I KAPPA B; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LUCIFERASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MAGNOLIA OFFICINALIS EXTRACT; MAGNOLOL; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL TYPE; CONTROLLED STUDY; CYTOSOL; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MAGNOLIACEAE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSIENT TRANSFECTION; UPREGULATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CYTOKINES; DIMERIZATION; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; LIGNANS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PHOSPHORYLATION; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

MAGNOLIA OFFICINALIS;

EID: 33846935734     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.12.004     Document Type: Article

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