Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells

British Journal of Pharmacology

Volumn 148, Issue 2, 2006, Pages 226-232

  Chen, Shih Chung ^a   Chang, Ying Ling ^b   Wang, Danny Ling ^c   Cheng, Jing Jy ^d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^d NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Cyclin D1; Endothelial cells; ICAM 1; Magnolol; STAT3

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLIN D1; HERBACEOUS AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; JANUS KINASE 1; JANUS KINASE 2; MAGNOLOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; SERINE DERIVATIVE; STAT3 PROTEIN; TYROSINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CATTLE; CELL ADHESION; CELL LINE; CELLS, CULTURED; CHEMOKINE CCL2; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL CELLS; GENE EXPRESSION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; LIGNANS; LUCIFERASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; STAT3 TRANSCRIPTION FACTOR;

EID: 33745054187     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706647     Document Type: Article

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