Magnolol has the ability to induce apoptosis in tumor cells

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 12, 2002, Pages 1546-1549

  Ikeda, Koji ^a   Nagase, Hisamitsu ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Antitumor effect; Apoptosis; Caspase; Magnolol; Mouse

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; MAGNOLOL; BIPHENYL DERIVATIVE; CASPASE; DNA FRAGMENT; LIGNAN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; TUMOR CELL; TUMOR CELL LINE; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; METABOLISM; PHYSIOLOGY;

APOPTOSIS; BIPHENYL COMPOUNDS; CASPASES; DNA FRAGMENTATION; HUMANS; LIGNANS; TUMOR CELLS, CULTURED;

EID: 1542281527     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1546     Document Type: Article

References (17)

1. Wyllie A. H., Kerr J. F R., Currie A R., Int. Rev Cytol, 68, 251-306 (1980).
2. Tewari M., Quan L. T., O'Rourke K., Desnoyers S., Zeng Z, Beidler D. R., Poirier G G., Salvesen G. S., Dixit V. M., Cell, 81, 801-809 (1995).
3. Teng C. M., Chen C C., Ko F. N., Lee L. G., Huang T. F., Chen Y. P., Hsu H. Y., Thromb. Res., 50, 757-765 (1988)
4. Fujita S., Taira J., Free Rad Biol. Med., 17, 273-277 (1994).
5. Teng C. M., Yu S. M., Chen C. C., Huang Y L., Huang T. F., Life Sci., 47, 1153-1161 (1990).
6. Wang J. P., Ho T. F., Chang L C., Chen C. C., J. Pharm. Pharmacol., 47, 857-860 (1995).
7. Nagase H., Ikeda K., Sakai Y., Planta Medica, 67, 705-708 (2001)
8. Ikeda K., Nagase H., Sakai Y., Phytotherapy Res., (in press).
9. Ikeda K., Nagase H., Phvtotherapy Res. (in press).
10. Mizukami S., Kikuchi T., Higuchi K, Urano Y., Mashiba T, Tsuruo T., Nagano T., FEBS Lett, 453, 356-360 (1999).
11. Wang J. P., Chen C. C, Eur. J. Pharmacol, 352, 329-334 (1998).
12. Wyllie A. H., Nature (London), 284, 555-556 (1980).
13. Kaiser N., Edelman I. S., Proc Natl. Acad. Sci. U.S A., 74, 638-642 (1977).
14. McConkey D. J., Hartzell P., Amador-Perez J. F., Orrenius S., Jondal M., J. Immunol., 143, 1801-1806 (1989).
15. McConkey D. J., Arch. Biochem. Biophys, 269, 365-370 (1989).
16. Vignaux F., J Exp Med, 181, 781-786 (1995).
17. Oshimi Y., Miyazaki S., J. Immunol., 154, 599-609 (1995).