A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic β-cell

American Journal of Physiology - Endocrinology and Metabolism

Volumn 292, Issue 2, 2007, Pages

  Westermark, Pål O ^a,b   Kotaleski, Jeanette Hellgren ^a   Björklund, Anneli ^c   Grill, Valdemar ^c,d   Lansner, Anders ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b HUMBOLDT UNIVERSITY   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Diabetes; Fatty acid oxidation; Potassium dependent adenosine triphosphate channel independent pathway of insulin secretion; Reduced nicotinamide adenine dinucleotide; Systems biology

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; MALATE DEHYDROGENASE (DECARBOXYLATING); MALONYL COENZYME A; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; DIABETES MELLITUS; ENZYME ACTIVITY; FATTY ACID OXIDATION; GLUCOSE OXIDATION; MATHEMATICAL MODEL; MITOCHONDRIAL RESPIRATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL TRANSPORT; CITRIC ACID CYCLE; FATTY ACIDS; GLYCOLYSIS; INSULIN-SECRETING CELLS; LIPID PEROXIDATION; MALATES; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; MODELS, THEORETICAL; NAD;

EID: 33846882164     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00589.2005     Document Type: Article

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