L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

Nature

Volumn 288, Issue 5787, 1980, Pages 187-189

  Sener, Abdullah ^a   Malaisse, Willy J ^a  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; AMINO ACID; GLUTAMATE DEHYDROGENASE; INSULIN; LEUCINE;

ANIMAL; ANIMAL EXPERIMENT; DOSE RESPONSE; DRUG RESPONSE; ENDOCRINE SYSTEM; ENZYME ACTIVATION; IN VITRO STUDY; INSULIN RELEASE; PANCREAS ISLET;

ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLUTAMATE DEHYDROGENASE; INSULIN; ISLETS OF LANGERHANS; LEUCINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0019133275     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/288187a0     Document Type: Article

References (15)

1. Randle, P. J., Ashcroft, S. J. H. & Gill, J. R. in Carbohydrate Metabolism and its Disorders (eds Dickens, F., Randle, P. J. & Whelan, W. J.) 427–447 (Academic, London, 1968).
2. Christensen, H. N. et al. Biochim. biophys. Acta 241, 341–348 (1971).
3. Malaisse, W. J., Sener, A., Herchuelz, A. & Hutton, J. C. Metabolism 28, 373–386 (1979).
4. Ashcroft, S. J. H. Diabetologia 18, 5–15 (1980).
5. Hutton, J. C., Sener, A. & Malaisse, W. J. Biochem. J. 184, 291–301 (1979).
6. Gylfe, E. Acta diabet. lat. 13, 20–24 (1976).
7. McGivan, J. C., Bradford, N. M., Crompton, M. & Chappell, J. B. Biochem. J. 134, 209–215 (1973).
8. Chapelle, S. Archs int. Physiol. Biochim. 80, 25–33 (1972).
9. Malaisse, W. J. et al. Molec. cell. Endocr. (in the press).
10. Malaisse, W. J., Brisson, G. & Malaisse-Lagae, F. J. Lab. clin. Med. 76, 895–902 (1970).
11. Malaisse, W. J., Hutton, J. C., Carpinelli, A. R., Herchuelz, A. & Sener, A. Diabetes 29, 431–437 (1980).
12. Sener, A. & Malaisse, W. J. C.r. hebd. Séanc. Acad. Sci., Paris 290, 1135–1137 (1980).
13. Hellerström, C., Anderson, A. & Welsh, M. Horm. Metab. Res. (in the press).
14. Joost, H. U., Panten, U., Ishida, H., Poser, W. & Hasselblatt, A. Life Sci. 16, 247–254 (1975).
15. Freinkel, N., Younsi, C. E. & Dawson, R. M. C. Proc. natn. Acad. Sci. U.S.A. 73, 3403–3407 (1976).