Model of β-cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables

American Journal of Physiology - Cell Physiology

Volumn 274, Issue 4 43-4, 1998, Pages

  Magnus, Gerhard ^a   Keizer, Joel ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine triphosphate sensitive potassium channel; Electrical activity; Pancreatic cell

Indexed keywords

GLUCOSE; MITOCHONDRIAL ENZYME; POTASSIUM CHANNEL;

ARTICLE; CALCIUM TRANSPORT; ELECTRIC ACTIVITY; GLUCOSE METABOLISM; MEMBRANE POTENTIAL; MITOCHONDRION; PANCREAS ISLET BETA CELL; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; REPOLARIZATION;

EID: 0031958402     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.274.4.c1158     Document Type: Article

References (61)

1. Ashcroft, S. Metabolic controls of insulin secretion. In: The Islets of Langerhans: Biochemistry, Physiology, and Pathology, edited by S. Cooperstein and D. Watkins. New York: Academic, 1981, p. 117-148.
2. Ashcroft, S., and M. Christie. Effects of glucose on the cytosolic ratio of reduced/oxidized nicotinamide-adenine dinucleotide phosphate in rat islets of Langerhans. Biochem. J. 184: 697-700, 1979.
3. Ashcroft, F. M., D. E. Harrison, and S. J. H. Ashcroft. Glucose induces closure of single potassium channels in isolated rate pancreatic β-cells. Nature 312: 446-448, 1984.
4. Ashcroft, F. M., and P. Rorsman. Electrophysiology of the pancreatic β-cell. Prog. Biophys. Mol. Biol. 54: 87-143, 1989.
5. Atwater, I., M. Kulkuljan, and E. Pérez-Armendariz. Ion channels in pancreatic β-cells. In: Molecular Biology of Diabetes. I. Autoimmunity and Genetics: Insulin Synthesis and Secretion, edited by B. Draznin and D. LeRoith. Totawa, NJ: Humana, 1994, p. 303-332.
6. Bertram, R., S. Smolen, A. Sherman, D. Mears, I. Atwater, F. Martin, and B. Soria. A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic β-cells. Biophys. J. 68: 2323-2332, 1995.
7. Boschero, A., S. Bordin, A. Sener, and W. Malaisse. D-Glucose and L-leucine metabolism in neonatal and adult cultured rat pancreatic islets. Mol. Cell. Endocrinol. 73: 63-71, 1990.
8. Cook, D. L., and C. N. Hales. Intracellular ATP directly blocks K channels in pancreatic B-cells. Nature 211: 269-271, 1984.
9. + channels in pancreatic β-cells. The "spare channel" hypothesis. Diabetes 37: 495-498, 1988.
10. Cooper, R., P. Randle, and R. Denton. Regulation of heart muscle pyruvate dehydrogenase kinase. Biochem. J. 143: 625-641, 1974.
11. Corkey, B., J. Duszynski, T. Rich, B. Matschinsky, and J. Williamson. Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria. J. Biol. Chem. 261: 2567-2574, 1986.
12. Damuni, Z., J. Humphreys, and L. Reed. Stimulation of pyruvate dehydrogenase phosphatase activity by polyamines. Biochem. Biophys. Res. Commun. 124: 95-99, 1984.
13. Dean, P. M., and E. K. Matthews. Electrical activity in pancreatic islets. Nature 219: 389-390, 1968.
14. Denton, R., P. Randle, and B. Martin. Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase. Biochem. J. 128: 161-163, 1972.
15. Duchen, M., P. Smith, and F. Ashcroft. Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic β-cells. Biochem. J. 294: 35-42, 1993.
16. Garfinkel, D., L. Garfinkel, M. Meglasson, and F. Matschinsky. Computer modeling identifies glucokinase as glucose sensor of pancreatic β-cells. Am. J. Physiol. 247 (Regulatory Integrative Comp. Physiol. 16): R527-R536, 1984.
17. Ghosh, A., P. Ronner, E. Cheong, P. Khalid, and F. Matschinsky. The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet β-cells in the isolated perfused rat pancreas. J. Biol. Chem. 266: 22887-22892, 1991.
18. 2+ concentration in an electrically excitable cell, the insulin-secreting pancreatic B-cell. J. Biol. Chem. 267: 20713-20720, 1992.
19. Gunter, T., K. Gunter, S.-S. Sheu, and C. Gavin. Mitochondrial calcium transport: physiological and pathological relevance. Am. J. Physiol. 267 (Cell Physiol. 36): C313-C339, 1994.
20. Gunter, T., and D. Pfeiffer. Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258 (Cell Physiol. 27): C755-C786, 1990.
21. Hansford, R., and L. Cohen. Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the eflect of fatty acids on pyruvate oxidation by rat heart mitochondria. Arch. Biochem. Biophys. 191: 65-81, 1978.
22. Hopkins, W., S. Fatherazi, B. Peter-Riesch, B. Corkey, and D. Cook. Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic β-cells and HIT cells. J. Membr. Biol. 129: 287-295, 1992.
23. Hougaard, D., J. Nielsen, and L.-I. Larsson. Localization and biosynthesis of polyamines in insulin-producing cells. Biochem. J. 238: 43-47, 1986.
24. 2+ oscillations. Cell Calcium 14: 397-410, 1993.
25. Keizer, J., and G. Magnus. The ATP-sensitive potassium channel and bursting in the pancreatic beta cell. A theoretical study. Biophys. J. 56: 229-242, 1989.
26. Kröner, H. Spermine, another specific allosteric activator of calcium uptake in rat liver mitochondria. Arch. Biochem. Biophys. 267: 205-210, 1988.
27. 2+ concentration in the pancreatic β cell. Proc. Natl. Acad. Sci. USA 93: 5161-5165, 1996.
28. Lehninger, A. Biochemistry (2nd ed.). New York: Worth, 1977, p. 514-517.
29. 2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets. J. Biol. Chem. 266: 9314-9319, 1991.
30. MacDonald, M. Calcium activation of pancreatic islet mitochondrial glycerol phosphate dehydrogenase. Horm. Metab. Res. 14: 678-679, 1982.
31. Magnus, G. Mitochondria-Based Model for Bursting and Its D-Glucose Dependence in the Pancreatic Beta Cell (PhD thesis). Davis: University of California, 1995.
32. 2+ handling. Am. J. Physiol. 273 (Cell Physiol. 42): C717-C733, 1997.
33. Magnus, G., and J. Keizer. Model of β-cell mitochondrial calcium handling and electrical activity. II. Mitochindrial variables. Am. J. Physiol. 274 (Cell Physiol. 43): C1174-C1184, 1998.
34. Malaisse, W., and A. Sener. Glucose-induced changes in cytosolic ATP content in pancreatic islets. Biochim. Biophys. Acta 927: 190-195, 1987.
35. 2+-sensitive dehydrogenases respond. Biochem. J. 264: 167-174, 1989.
36. 2+-sensitive dehydrogenases within intact rat kidney mitochondria. Biochim. Biophys. Acta 934: 282-292, 1988.
37. 2+-sensitive dehydrogenases within intact uncoupled mitochondria from the white and brown adipose tissue of the rat. Biochem. J. 190: 95-105, 1980.
38. McCormack, J., A. Halestrap, and R. Denton. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70: 391-425, 1990.
39. McCormack, J., E. Longo, and B. Corkey. Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets. Biochem. J. 267: 527-530, 1990.
40. Meglasson, M., and F. Matschinsky. New perspectives on pancreatic islet glucokinase. Am. J. Physiol. 246 (Endocrinol. Metab. 9): E1-E13, 1984.
41. Meissner, H., and M. Preissler. Ionic mechanisms of the glucose-induced membrane potential changes in B-cells. In: Biochemistry and Biophysics of the Pancreatic B-Cell, edited by W. Malaisse. Stuttgart: Thieme Verlag, 1980, p. 91-99.
42. 2+ concentration. Biochem. J. 256: 403-412, 1988.
43. 2 consumption by isolated pancreatic islets, as measured in a microincubation system with a dark-type electrode. Endocrinology 111: 1595-1600, 1982.
44. Reed, L. Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle. Curr. Top. Cell. Regul. 18: 95-106, 1981.
45. 2+ efflux in heart and liver mitochondria. Biochem. J. 246: 271-277, 1987.
46. Rojas, E., J. Hidalgo, P. Carroll, M. Li, and I. Atwater. Anew class of calcium channels activated by glucose in human pancreatic β-cells. FEBS Lett. 261: 265-270, 1990.
47. 2+ to supramicromolar levels in a pancreatic β-cell line. Possible role in glucose and agonist-induced insulin secretion. J. Biol. Chem. 268: 22385-22390, 1993.
48. Sala, S., R. Parsey, A. Cohen, and D. Matteson. Analysis and use of the perforated patch technique for recording ionic currents in pancreatic β-cells. J. Membr. Biol. 122: 177-187, 1991.
49. Sánchez-Andrés, J. V., A. Gomis, and M. Valdeolmillos. The electrical activity of mouse pancreatic β-cells recorded in vivo shows glucose-dependence oscillations. J. Physiol. (Lond.) 486: 223-228, 1995.
50. i oscillations due to bursting electrical activity in single pancreatic islets. Pflügers Arch. 418: 417-422, 1991.
51. + in rat islets. J. Clin. Invest. 62: 868-878, 1978.
52. Sener, A., J. Levy, and W. Malaisse. The stimulus-secretion coupling of glucose-induced insulin release. XXIII. Does glycolysis control calcium transport in the β-cell? Biochem. J. 156: 521-525, 1976.
53. 2+-sensitive 2-ketoglutarate dehydrogenase in the regulation of mitochondrial function. Biochim. Biophys. Acta 1019: 42-50, 1990.
54. Sherman, A. Contributions of modeling to understanding stimulus-secretion coupling in pancreatic β-cells. Am. J. Physiol. 270 (Endocrinol. Metab. 34): E362-E372, 1996.
55. 2+ currents and bursting mechanisms for the mouse pancreatic β-cell. J. Membr. Biol. 127: 9-19, 1992.
56. Thomas, A., T. Diggle, and R. Denton. Sensitivity of pyruvate dehydrogenase phosphatase phosphatase to magnesium ions. Similar effects of spermine and insulin. Biochem. J. 238: 83-91, 1986.
57. Welsh, M. The Importance of Substrate Metabolism in the Regulation of Insulin Release by Mouse Pancreatic Islets (PhD thesis). Uppsala, Sweden: Uppsala University.
58. 2+ stimulation of rat liver mitochondrial glycerophosphate dehydrogenase. J. Biol. Chem. 256: 12767-12771, 1981.
59. Wilson, D., D. Nelson, and M. Erecińska. Binding of the intramitochondrial ADP and its relationship to adenine nucleotide translocation. FEBS Lett. 143: 228-232, 1982.
60. Worley, J. F., III, M. S. McIntyre, R. J. Mertz, M. W. Roe, and I. D. Dukes. Endoplasmic reticulum calcium store regulates membrane potential in mouse islet β-cells. J. Biol. Chem. 269: 14395-14362, 1994.
61. Zawalich, W., and F. Matschinsky. Sequential analysis of the releasing and fuel function of glucose in isolated perifused pancreatic islets. Endocrinology 100: 1-8, 1977.