-
1
-
-
33645462044
-
Cytokine signalling in embryonic stem cells
-
Kristensen D.M., Kalisz M., and Nielsen J.H. Cytokine signalling in embryonic stem cells. APMIS 113 (2005) 756-772
-
(2005)
APMIS
, vol.113
, pp. 756-772
-
-
Kristensen, D.M.1
Kalisz, M.2
Nielsen, J.H.3
-
2
-
-
0037726553
-
IL-4 acts as a myoblast recruitment factor during mammalian muscle growth
-
Horsley V., Jansen K.M., Mills S.T., and Pavlath G.K. IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell 113 (2003) 483-494
-
(2003)
Cell
, vol.113
, pp. 483-494
-
-
Horsley, V.1
Jansen, K.M.2
Mills, S.T.3
Pavlath, G.K.4
-
3
-
-
0036885067
-
The lineage decisions of helper T cells
-
Murphy K.M., and Reiner S.L. The lineage decisions of helper T cells. Nature Rev. Immunol. 2 (2002) 933-944
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
4
-
-
33646490285
-
Lineage-specific hematopoietic growth factors
-
Kaushansky K. Lineage-specific hematopoietic growth factors. N. Engl. J. Med. 354 (2006) 2034-2045
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2034-2045
-
-
Kaushansky, K.1
-
5
-
-
9644295710
-
Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
-
Kovanen P.E., and Leonard W.J. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol. Rev. 202 (2004) 67-83
-
(2004)
Immunol. Rev.
, vol.202
, pp. 67-83
-
-
Kovanen, P.E.1
Leonard, W.J.2
-
7
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: progressing towards the dream
-
Arkin M.R., and Wells J.A. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nature Rev. Drug Discov. 3 (2004) 301-317
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
8
-
-
0037064548
-
Structure, binding, and antagonists in the IL-4/IL-13 receptor system
-
Mueller T.D., Zhang J.L., Sebald W., and Duschl A. Structure, binding, and antagonists in the IL-4/IL-13 receptor system. Biochim. Biophys. Acta 1592 (2002) 237-250
-
(2002)
Biochim. Biophys. Acta
, vol.1592
, pp. 237-250
-
-
Mueller, T.D.1
Zhang, J.L.2
Sebald, W.3
Duschl, A.4
-
9
-
-
0026598960
-
Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
-
de Vos A.M., Ultsch M., and Kossiakoff A.A. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255 (1992) 306-312
-
(1992)
Science
, vol.255
, pp. 306-312
-
-
de Vos, A.M.1
Ultsch, M.2
Kossiakoff, A.A.3
-
10
-
-
0026764441
-
Rational design of potent antagonists to the human growth hormone receptor
-
Fuh G., et al. Rational design of potent antagonists to the human growth hormone receptor. Science 256 (1992) 1677-1680
-
(1992)
Science
, vol.256
, pp. 1677-1680
-
-
Fuh, G.1
-
11
-
-
0027232919
-
The hematopoietin receptor superfamily
-
Cosman D. The hematopoietin receptor superfamily. Cytokine 5 (1993) 95-106
-
(1993)
Cytokine
, vol.5
, pp. 95-106
-
-
Cosman, D.1
-
12
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin C.H. Dimerization of cell surface receptors in signal transduction. Cell 80 (1995) 213-223
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
13
-
-
0033548259
-
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
-
Livnah O., et al. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science 283 (1999) 987-990
-
(1999)
Science
, vol.283
, pp. 987-990
-
-
Livnah, O.1
-
14
-
-
0033548048
-
Erythropoietin receptor activation by a ligand-induced conformation change
-
Remy I., Wilson I.A., and Michnick S.W. Erythropoietin receptor activation by a ligand-induced conformation change. Science 283 (1999) 990-993
-
(1999)
Science
, vol.283
, pp. 990-993
-
-
Remy, I.1
Wilson, I.A.2
Michnick, S.W.3
-
15
-
-
0031766635
-
An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation
-
Livnah O., et al. An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation. Nature Struct. Biol. 5 (1998) 993-1004
-
(1998)
Nature Struct. Biol.
, vol.5
, pp. 993-1004
-
-
Livnah, O.1
-
17
-
-
0035102191
-
The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif
-
Constantinescu S.N., Huang L.J., Nam H., and Lodish H.F. The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif. Mol. Cell 7 (2001) 377-385
-
(2001)
Mol. Cell
, vol.7
, pp. 377-385
-
-
Constantinescu, S.N.1
Huang, L.J.2
Nam, H.3
Lodish, H.F.4
-
18
-
-
0344413478
-
Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer
-
Seubert N., et al. Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer. Mol. Cell 12 (2003) 1239-1250
-
(2003)
Mol. Cell
, vol.12
, pp. 1239-1250
-
-
Seubert, N.1
-
19
-
-
9644260490
-
A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis
-
Jiang J., et al. A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis. Mol. Endocrinol. 18 (2004) 2981-2996
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2981-2996
-
-
Jiang, J.1
-
20
-
-
7244226345
-
Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization
-
Wan Y., McDevitt A., Shen B., Smythe M.L., and Waters M.J. Increased site 1 affinity improves biopotency of porcine growth hormone. Evidence against diffusion dependent receptor dimerization. J. Biol. Chem. 279 (2004) 44775-44784
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44775-44784
-
-
Wan, Y.1
McDevitt, A.2
Shen, B.3
Smythe, M.L.4
Waters, M.J.5
-
21
-
-
26944493862
-
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
-
Brown R.J., et al. Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nature Struct. Mol. Biol. 12 (2005) 814-821
-
(2005)
Nature Struct. Mol. Biol.
, vol.12
, pp. 814-821
-
-
Brown, R.J.1
-
22
-
-
0033010373
-
The IL-4 receptor: signaling mechanisms and biologic functions
-
Nelms K., Keegan A.D., Zamorano J., Ryan J.J., and Paul W.E. The IL-4 receptor: signaling mechanisms and biologic functions. Annu. Rev. Immunol. 17 (1999) 701-738
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
23
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto T., Taga T., and Akira S. Cytokine signal transduction. Cell 76 (1994) 253-262
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
24
-
-
0037393323
-
IL-13 receptors and signaling pathways: an evolving web
-
Hershey G.K. IL-13 receptors and signaling pathways: an evolving web. J. Allergy Clin. Immunol. 111 (2003) 677-690
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 677-690
-
-
Hershey, G.K.1
-
25
-
-
0037195960
-
Kinetic analysis of the interleukin-13 receptor complex
-
Andrews A.L., Holloway J.W., Puddicombe S.M., Holgate S.T., and Davies D.E. Kinetic analysis of the interleukin-13 receptor complex. J. Biol. Chem. 277 (2002) 46073-46078
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46073-46078
-
-
Andrews, A.L.1
Holloway, J.W.2
Puddicombe, S.M.3
Holgate, S.T.4
Davies, D.E.5
-
26
-
-
0030695442
-
Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study
-
Damjanovich S., et al. Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study. Proc. Natl Acad. Sci. USA 94 (1997) 13134-13139
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13134-13139
-
-
Damjanovich, S.1
-
27
-
-
3342924000
-
IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells
-
Vamosi G., et al. IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells. Proc. Natl. Acad. Sci. USA 101 (2004) 11082-11087
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11082-11087
-
-
Vamosi, G.1
-
28
-
-
1942541221
-
Lipid rafts in cytokine signaling
-
Rao R., Logan B., Forrest K., Roszman T.L., and Goebel J. Lipid rafts in cytokine signaling. Cytokine Growth Factor Rev. 15 (2004) 103-110
-
(2004)
Cytokine Growth Factor Rev.
, vol.15
, pp. 103-110
-
-
Rao, R.1
Logan, B.2
Forrest, K.3
Roszman, T.L.4
Goebel, J.5
-
29
-
-
2342638606
-
-
Academic Press, London
-
Fitzgerald K.A., O'Neill L.A.J., Gearing A.J.H., and Callard R.E. The Cytokine Facts Book (2001), Academic Press, London
-
(2001)
The Cytokine Facts Book
-
-
Fitzgerald, K.A.1
O'Neill, L.A.J.2
Gearing, A.J.H.3
Callard, R.E.4
-
30
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan J.F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. USA 87 (1990) 6934-6938
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
32
-
-
19944427133
-
The Janus kinases (Jaks)
-
Yamaoka K., et al. The Janus kinases (Jaks). Genome Biol. 5 (2004) 253
-
(2004)
Genome Biol.
, vol.5
, pp. 253
-
-
Yamaoka, K.1
-
33
-
-
2442710342
-
Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited
-
Hofmann S.R., et al. Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited. Mol. Cell Biol. 24 (2004) 5039-5049
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 5039-5049
-
-
Hofmann, S.R.1
-
34
-
-
0033574713
-
Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface
-
Hage T., Sebald W., and Reinemer P. Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface. Cell 97 (1999) 271-281
-
(1999)
Cell
, vol.97
, pp. 271-281
-
-
Hage, T.1
Sebald, W.2
Reinemer, P.3
-
35
-
-
0031048778
-
A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain
-
Wang Y., Shen B.J., and Sebald W. A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain. Proc. Natl. Acad. Sci. USA 94 (1997) 1657-1662
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1657-1662
-
-
Wang, Y.1
Shen, B.J.2
Sebald, W.3
-
36
-
-
0036300916
-
The high-affinity interaction of human IL-4 and the receptor alpha chain is constituted by two independent binding clusters
-
Zhang J.L., Simeonowa I., Wang Y., and Sebald W. The high-affinity interaction of human IL-4 and the receptor alpha chain is constituted by two independent binding clusters. J. Mol. Biol. 315 (2002) 399-407
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 399-407
-
-
Zhang, J.L.1
Simeonowa, I.2
Wang, Y.3
Sebald, W.4
-
37
-
-
0029798402
-
Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A
-
Livnah O., et al. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science 273 (1996) 464-471
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
-
38
-
-
0029738872
-
Experimentally determined hydrophobicity scale for proteins at membrane interfaces
-
Wimley W.C., and White S.H. Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nature Struct. Biol. 3 (1996) 842-848
-
(1996)
Nature Struct. Biol.
, vol.3
, pp. 842-848
-
-
Wimley, W.C.1
White, S.H.2
-
39
-
-
0029103215
-
Characterization and modeling of membrane proteins using sequence analysis
-
Reithmeier R.A. Characterization and modeling of membrane proteins using sequence analysis. Curr. Opin. Struct. Biol. 5 (1995) 491-500
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 491-500
-
-
Reithmeier, R.A.1
-
40
-
-
0032987478
-
Membrane protein folding and stability: physical principles
-
White S.H., and Wimley W.C. Membrane protein folding and stability: physical principles. Annu. Rev. Biophys. Biomol. Struct. 28 (1999) 319-365
-
(1999)
Annu. Rev. Biophys. Biomol. Struct.
, vol.28
, pp. 319-365
-
-
White, S.H.1
Wimley, W.C.2
-
41
-
-
0035795721
-
Amino acid distributions in integral membrane protein structures
-
Ulmschneider M.B., and Sansom M.S. Amino acid distributions in integral membrane protein structures. Biochim. Biophys. Acta 1512 (2001) 1-14
-
(2001)
Biochim. Biophys. Acta
, vol.1512
, pp. 1-14
-
-
Ulmschneider, M.B.1
Sansom, M.S.2
-
42
-
-
0033061633
-
Simulation study of a gramicidin/lipid bilayer system in excess water and lipid. I. Structure of the molecular complex
-
Chiu S.W., Subramaniam S., and Jakobsson E. Simulation study of a gramicidin/lipid bilayer system in excess water and lipid. I. Structure of the molecular complex. Biophys. J. 76 (1999) 1929-1938
-
(1999)
Biophys. J.
, vol.76
, pp. 1929-1938
-
-
Chiu, S.W.1
Subramaniam, S.2
Jakobsson, E.3
-
43
-
-
0032552880
-
The preference of tryptophan for membrane interfaces
-
Yau W.M., Wimley W.C., Gawrisch K., and White S.H. The preference of tryptophan for membrane interfaces. Biochemistry 37 (1998) 14713-14718
-
(1998)
Biochemistry
, vol.37
, pp. 14713-14718
-
-
Yau, W.M.1
Wimley, W.C.2
Gawrisch, K.3
White, S.H.4
-
44
-
-
33749347076
-
Interactions of tryptophan, tryptophan peptides, and tryptophan alkyl esters at curved membrane interfaces
-
Liu W., and Caffrey M. Interactions of tryptophan, tryptophan peptides, and tryptophan alkyl esters at curved membrane interfaces. Biochemistry 45 (2006) 11713-11726
-
(2006)
Biochemistry
, vol.45
, pp. 11713-11726
-
-
Liu, W.1
Caffrey, M.2
-
45
-
-
0036286654
-
Free energy simulations come of age: protein-ligand recognition
-
Simonson T., Archontis G., and Karplus M. Free energy simulations come of age: protein-ligand recognition. Accts Chem. Res. 35 (2002) 430-437
-
(2002)
Accts Chem. Res.
, vol.35
, pp. 430-437
-
-
Simonson, T.1
Archontis, G.2
Karplus, M.3
-
46
-
-
29144470089
-
Simple models for hydrophobic hydration
-
Hofinger S., and Zerbetto F. Simple models for hydrophobic hydration. Chem. Soc. Rev. 34 (2005) 1012-1020
-
(2005)
Chem. Soc. Rev.
, vol.34
, pp. 1012-1020
-
-
Hofinger, S.1
Zerbetto, F.2
-
47
-
-
84961980477
-
Quantum mechanical continuum solvation models
-
Tomasi J., Mennucci B., and Cammi R. Quantum mechanical continuum solvation models. Chem. Rev. 105 (2005) 2999-3093
-
(2005)
Chem. Rev.
, vol.105
, pp. 2999-3093
-
-
Tomasi, J.1
Mennucci, B.2
Cammi, R.3
-
48
-
-
0028052289
-
The role of the WSXWS equivalent motif in growth hormone receptor function
-
Baumgartner J.W., Wells C.A., Chen C.M., and Waters M.J. The role of the WSXWS equivalent motif in growth hormone receptor function. J. Biol. Chem. 269 (1994) 29094-29101
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29094-29101
-
-
Baumgartner, J.W.1
Wells, C.A.2
Chen, C.M.3
Waters, M.J.4
-
49
-
-
0028099403
-
Three conserved motifs in the extracellular domain of the human granulocyte-macrophage colony-stimulating factor receptor subunit are essential for ligand binding and surface expression
-
Doshi P.D., and DiPersio J.F. Three conserved motifs in the extracellular domain of the human granulocyte-macrophage colony-stimulating factor receptor subunit are essential for ligand binding and surface expression. Blood 84 (1994) 2539-2553
-
(1994)
Blood
, vol.84
, pp. 2539-2553
-
-
Doshi, P.D.1
DiPersio, J.F.2
-
50
-
-
0029928504
-
Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor
-
Hilton D.J., Watowich S.S., Katz L., and Lodish H.F. Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor. J. Biol. Chem. 271 (1996) 4699-4708
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4699-4708
-
-
Hilton, D.J.1
Watowich, S.S.2
Katz, L.3
Lodish, H.F.4
-
51
-
-
0025942918
-
The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction
-
Miyazaki T., Maruyama M., Yamada G., Hatakeyama M., and Taniguchi T. The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction. EMBO J. 10 (1991) 3191-3197
-
(1991)
EMBO J.
, vol.10
, pp. 3191-3197
-
-
Miyazaki, T.1
Maruyama, M.2
Yamada, G.3
Hatakeyama, M.4
Taniguchi, T.5
-
52
-
-
0026765013
-
Mutations in the WSAWSE and cytosolic domains of the erythropoietin receptor affect signal transduction and ligand binding and internalization
-
Quelle D.E., Quelle F.W., and Wojchowski D.M. Mutations in the WSAWSE and cytosolic domains of the erythropoietin receptor affect signal transduction and ligand binding and internalization. Mol. Cell Biol. 12 (1992) 4553-4561
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 4553-4561
-
-
Quelle, D.E.1
Quelle, F.W.2
Wojchowski, D.M.3
-
53
-
-
0028147363
-
Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding
-
Ronco L.V., et al. Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding. J. Biol. Chem. 269 (1994) 277-283
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 277-283
-
-
Ronco, L.V.1
-
54
-
-
0026643982
-
Mutations in the Trp-Ser-X-Trp-Ser motif of the erythropoietin receptor abolish processing, ligand binding, and activation of the receptor
-
Yoshimura A., et al. Mutations in the Trp-Ser-X-Trp-Ser motif of the erythropoietin receptor abolish processing, ligand binding, and activation of the receptor. J. Biol. Chem. 267 (1992) 11619-11625
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11619-11625
-
-
Yoshimura, A.1
|