Comparison of gene expression efficiency and innate immune response induced by Ad vector and lipoplex

Journal of Controlled Release

Volumn 117, Issue 3, 2007, Pages 430-437

  Sakurai, Haruna ^a,b   Sakurai, Fuminori ^a   Kawabata, Kenji ^a   Sasaki, Tomomi ^a   Koizumi, Naoya ^a   Huang, Haiying ^a   Tashiro, Katsuhisa ^a,b   Kurachi, Shinnosuke ^a,b   Nakagawa, Shinsaku ^b   Mizuguchi, Hiroyuki ^a,b  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Adenovirus vector; Gene therapy; In vivo gene expression; Innate immunity; Lipoplex

Indexed keywords

DNA; GENES; GENETIC ENGINEERING; LIPIDS; TOXICITY; TUMORS;

ADENOVIRUS VECTOR; GENE THERAPY; IN VIVO GENE EXPRESSION; INNATE IMMUNITY; LIPOPLEX;

IMMUNOLOGY;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ADENOVIRUS VECTOR; CHOLESTEROL; CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPLEX; PLASMID DNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG SAFETY; EXPRESSION VECTOR; FEMALE; GENE EXPRESSION; GENETIC TRANSDUCTION; IMMUNE RESPONSE; INJECTION; INNATE IMMUNITY; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; CYTOKINES; DRUG CARRIERS; EXCIPIENTS; FATTY ACIDS, MONOUNSATURATED; FEMALE; GENE EXPRESSION; GENETIC VECTORS; HEPATITIS, TOXIC; IMMUNITY, NATURAL; INTERLEUKIN-12; INTERLEUKIN-6; LIPOSOMES; LIVER; MICE; MICE, INBRED C57BL; PARAFFIN EMBEDDING; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33846846616     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.11.030     Document Type: Article

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