A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors

Human Gene Therapy

Volumn 10, Issue 12, 1999, Pages 2013-2017

  Mizuguchi, Hiroyuki ^a   Kay, Mark A ^b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

ADENOVIRUS; ARTICLE; GENE DELETION; GENETIC RECOMBINATION;

ADENOVIRIDAE; ADENOVIRUS E1 PROTEINS; ADENOVIRUS E3 PROTEINS; ADENOVIRUS E4 PROTEINS; BETA-GALACTOSIDASE; GENE DELETION; GENETIC VECTORS; PLASMIDS; RECOMBINANT PROTEINS;

ADENOVIRIDAE; DNA VIRUSES;

EID: 0033543098     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950017374     Document Type: Article

References (10)

1. BETT, A.J., HADDARA, W., PREVEC, L., and GRAHAM, F.L. (1994). An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc. Natl. Acad. Sci. U.S.A. 91, 8802-8806.
2. CHARTIER, C., DEGRYSE, E., GANTZER, M., DIETERLE, A., PAVIRANI, A., and MEHTALI, M. (1996). Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J. Virol. 70, 4805-4810.
3. CROUZET, J., NAUDIN, L., ORSINI, C., VIGNE, E., FERREO, L., LE ROUX, A., BENOIT, P., LATTA, M., TORRENT, C., BRANELLEC, D., DENEFLE, P., MAYAUX, J.F., PERRICAUDET, M., and YEH, P. (1997). Recombinational construction in Escherichia coli of infectious adenoviral genomes. Proc. Natl. Acad. Sci. U.S.A. 94, 1414-1419.
4. GIMBLE, F.S., and THORNER, J. (1992). Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature (London) 357, 301-306.
5. HE, T.C., ZHOU, S., DA COSTA, L.T., YU, J., KINZLER, K.W., and VOGELSTEIN, B. (1998). A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. U.S.A. 95, 2509-2514.
6. KETNER, G., SPENCER, F., TUGENDREICH, S., CONNELLY, C., and HIETER, P. (1994). Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone. Proc. Natl. Acad. Sci. U.S.A. 91, 6186-6190.
7. KROUGLIAK, V., and GRAHAM, F.L. (1995). Development of cell lines capable of complementing El, E4, and protein IX defective adenovirus type 5 mutants. Hum. Gene Ther. 6, 1575-1586.
8. LIEBER, A., HE, C.-Y., KIRILLOVA, I., and KAY, M.A. (1996). Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J. Virol. 70, 8944-8960.
9. MARSHALL, P., and LEMIEUX, C. (1991). Cleavage pattern of the homing endonuclease encoded by the fifth intron in the chloroplast large subunit rRNA-encoding gene of Chlamydomonas eugametos. Gene 104, 241-245.
10. MIZUGUCHI, H., and KAY, M.A. (1998). Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation. Hum. Gene Ther. 9, 2577-2583.