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Volumn 9, Issue 1, 2007, Pages 44-54

Enhanced gene expression through temperature profile-induced variations in molecular architecture of thermoresponsive polymer vectors

Author keywords

Non viral vector; Poly(ethyleneimine); Poly(N isopropylacrylamide); Polycation; Thermoresponsive polymers; Transfection

Indexed keywords

PLASMID DNA; POLYCATION; POLYETHYLENEIMINE POLY(N ISOPROPYLACRYLAMIDE) CONJUGATE; UNCLASSIFIED DRUG;

EID: 33846842309     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.992     Document Type: Article
Times cited : (40)

References (37)
  • 1
    • 3042814407 scopus 로고    scopus 로고
    • Controlled release systems for DNA delivery
    • Pannier AK, Shea LD. Controlled release systems for DNA delivery. Mol Ther 2004; 10: 19-26.
    • (2004) Mol Ther , vol.10 , pp. 19-26
    • Pannier, A.K.1    Shea, L.D.2
  • 2
    • 14044250982 scopus 로고    scopus 로고
    • Formation and intracellular trafficking of lipoplexes and polyplexes
    • Elouahabi A, Ruysschaert JM. Formation and intracellular trafficking of lipoplexes and polyplexes. Mol Ther 2005; 11: 336-347.
    • (2005) Mol Ther , vol.11 , pp. 336-347
    • Elouahabi, A.1    Ruysschaert, J.M.2
  • 3
    • 27244449312 scopus 로고    scopus 로고
    • A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids
    • Read ML, Singh S, Ahmed Z, et al. A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids. Nucleic Acids Res 2005; 33: e86.
    • (2005) Nucleic Acids Res , vol.33
    • Read, M.L.1    Singh, S.2    Ahmed, Z.3
  • 4
  • 5
    • 20744433079 scopus 로고    scopus 로고
    • Intracellular trafficking of adeno-associated viral vectors
    • Ding W, Zhang L, Yan Z, Engelhardt JF. Intracellular trafficking of adeno-associated viral vectors. Gene Ther 2005; 12: 873-880.
    • (2005) Gene Ther , vol.12 , pp. 873-880
    • Ding, W.1    Zhang, L.2    Yan, Z.3    Engelhardt, J.F.4
  • 6
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003; 2: 347-360.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 7
    • 27744437341 scopus 로고    scopus 로고
    • Promoter dependence of plasmid-pluronics targeted alpha galactosidase A expression in skeletal muscle of Fabry mice
    • Lavigne MD, Pohlschmidt M, Novo JF, et al. Promoter dependence of plasmid-pluronics targeted alpha galactosidase A expression in skeletal muscle of Fabry mice. Mol Ther 2005; 12: 985-990.
    • (2005) Mol Ther , vol.12 , pp. 985-990
    • Lavigne, M.D.1    Pohlschmidt, M.2    Novo, J.F.3
  • 8
    • 3042537439 scopus 로고    scopus 로고
    • Thermo and pH responsive polymers as gene delivery vectors: Effect of polymer architecture on DNA complexation in vitro
    • Twaites BR, de las Heras Alarcon C, Cunliffe D, et al. Thermo and pH responsive polymers as gene delivery vectors: effect of polymer architecture on DNA complexation in vitro. J Control Release 2004; 97: 551-566.
    • (2004) J Control Release , vol.97 , pp. 551-566
    • Twaites, B.R.1    de las Heras Alarcon, C.2    Cunliffe, D.3
  • 9
    • 0033524453 scopus 로고    scopus 로고
    • Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus
    • Zanta M. Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A 1999; 96: 91-96.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 91-96
    • Zanta, M.1
  • 10
    • 4344653923 scopus 로고    scopus 로고
    • Genuine DNA/polyethylenimine (PEI) complexes improve transfection properties and cell survival
    • Erbacher P, Bettinger T, Brion E, et al. Genuine DNA/polyethylenimine (PEI) complexes improve transfection properties and cell survival. J Drug Target 2004; 12: 223-236.
    • (2004) J Drug Target , vol.12 , pp. 223-236
    • Erbacher, P.1    Bettinger, T.2    Brion, E.3
  • 11
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
    • Moghimi SM, Symonds P, Murray JC, Hunter AC, Debska G, Szewczyk A. A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 2005; 11: 990-995.
    • (2005) Mol Ther , vol.11 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 12
    • 0036525712 scopus 로고    scopus 로고
    • Gene delivery using temperature-responsive polymeric carriers
    • Yokoyama M. Gene delivery using temperature-responsive polymeric carriers. Drug Discov Today 2002; 7: 426-432.
    • (2002) Drug Discov Today , vol.7 , pp. 426-432
    • Yokoyama, M.1
  • 13
    • 0034738843 scopus 로고    scopus 로고
    • Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers
    • Kurisawa M, Yokoyama M, Okano T. Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers. J. Control Release 2000; 68: 1-8.
    • (2000) J. Control Release , vol.68 , pp. 1-8
    • Kurisawa, M.1    Yokoyama, M.2    Okano, T.3
  • 14
    • 0042827496 scopus 로고    scopus 로고
    • Stimuli-responsive gene delivery vectors
    • Oupicky D, Diwadkar V. Stimuli-responsive gene delivery vectors. Curr Opin Mol Ther 2003; 5: 345-350.
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 345-350
    • Oupicky, D.1    Diwadkar, V.2
  • 15
    • 1842638508 scopus 로고    scopus 로고
    • In vitro transfection of HeLa cells with temperature sensitive polycationic copolymers
    • Turk M, Dincer S, Yulug IG, Piskin E. In vitro transfection of HeLa cells with temperature sensitive polycationic copolymers. J Control Release 2004; 96: 325-340.
    • (2004) J Control Release , vol.96 , pp. 325-340
    • Turk, M.1    Dincer, S.2    Yulug, I.G.3    Piskin, E.4
  • 16
    • 0034601880 scopus 로고    scopus 로고
    • Gene expression control by temperature with thermo-responsive polymeric gene carriers
    • Kurisawa M, Yokoyama M, Okano T. Gene expression control by temperature with thermo-responsive polymeric gene carriers. J Control Release 2000; 69: 127-137.
    • (2000) J Control Release , vol.69 , pp. 127-137
    • Kurisawa, M.1    Yokoyama, M.2    Okano, T.3
  • 17
    • 33646359427 scopus 로고    scopus 로고
    • Temperature-controlled properties of DNA complexes with poly(ethylenimine)-graft-poly(N-isopropylacrylamide)
    • Bisht HS, Manickam DS, You YZ, Oupicky D. Temperature-controlled properties of DNA complexes with poly(ethylenimine)-graft-poly(N-isopropylacrylamide). Biomacromolecules 2006; 7: 1169-1178.
    • (2006) Biomacromolecules , vol.7 , pp. 1169-1178
    • Bisht, H.S.1    Manickam, D.S.2    You, Y.Z.3    Oupicky, D.4
  • 18
    • 27744516008 scopus 로고    scopus 로고
    • Thermoresponsive polymers as gene delivery vectors: Cell viability, DNA transport and transfection studies
    • Twaites BR, De las Heras Alarcón C, Lavigne M, et al. Thermoresponsive polymers as gene delivery vectors: cell viability, DNA transport and transfection studies. J Control Release 2005; 108: 472-483.
    • (2005) J Control Release , vol.108 , pp. 472-483
    • Twaites, B.R.1    De las Heras Alarcón, C.2    Lavigne, M.3
  • 19
    • 33846802491 scopus 로고    scopus 로고
    • Synthesis and characterization of variable architecture thermo-sensitive polymers for complexation with DNA
    • in press
    • Pennadam SS, Ellis JE, Lavigne MD, Gorecki DC, Davies MC, Alexander C. Synthesis and characterization of variable architecture thermo-sensitive polymers for complexation with DNA. Langmuir 2006; in press.
    • (2006) Langmuir
    • Pennadam, S.S.1    Ellis, J.E.2    Lavigne, M.D.3    Gorecki, D.C.4    Davies, M.C.5    Alexander, C.6
  • 20
    • 27944472249 scopus 로고    scopus 로고
    • Biophysical and transfection of studies of an amine-modified poly(vinyl alcohol) for gene delivery
    • Wittmar M, Ellis JS, Morell F, et al. Biophysical and transfection of studies of an amine-modified poly(vinyl alcohol) for gene delivery. Bioconjugate Chem 2005; 16: 1390-1398.
    • (2005) Bioconjugate Chem , vol.16 , pp. 1390-1398
    • Wittmar, M.1    Ellis, J.S.2    Morell, F.3
  • 21
    • 0037192546 scopus 로고    scopus 로고
    • Fate of excited probes in micellar systems
    • Capek I. Fate of excited probes in micellar systems. Adv Colloid Interface Sci 2002; 97: 89.
    • (2002) Adv Colloid Interface Sci , vol.97 , pp. 89
    • Capek, I.1
  • 23
    • 0038738155 scopus 로고    scopus 로고
    • Thermal response of poly(n-isopropylacrylamide) brushes probed by surface plasmon resonance
    • Balamurugan S, Mendez S, Balamurugan SS, O'Brien MJ, Lopez GP. Thermal response of poly(n-isopropylacrylamide) brushes probed by surface plasmon resonance. Langmuir 2003; 19: 2545-2549.
    • (2003) Langmuir , vol.19 , pp. 2545-2549
    • Balamurugan, S.1    Mendez, S.2    Balamurugan, S.S.3    O'Brien, M.J.4    Lopez, G.P.5
  • 24
    • 1642619464 scopus 로고    scopus 로고
    • Temperature-dependent conformational change of PNIPAM grafted chains at high surface density in water
    • Yim H, Kent MS, Mendez S, et al. Temperature-dependent conformational change of PNIPAM grafted chains at high surface density in water. Macromolecules 2004; 37: 1994-1997.
    • (2004) Macromolecules , vol.37 , pp. 1994-1997
    • Yim, H.1    Kent, M.S.2    Mendez, S.3
  • 25
    • 0037109708 scopus 로고    scopus 로고
    • Thermally controlled association in aqueous solutions of poly(L-lysine) grafted with poly(N-isopropylacrylamide)
    • Konak C, Reschel T, Oupicky D, Ulbrich K. Thermally controlled association in aqueous solutions of poly(L-lysine) grafted with poly(N-isopropylacrylamide). Langmuir 2002; 18: 8217-8222.
    • (2002) Langmuir , vol.18 , pp. 8217-8222
    • Konak, C.1    Reschel, T.2    Oupicky, D.3    Ulbrich, K.4
  • 27
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schuller S, Kircheis R, Wagner E. PEGylated DNA/ transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 1999; 6: 595-605.
    • (1999) Gene Ther , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 28
    • 0142229694 scopus 로고    scopus 로고
    • Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase I
    • Abdelhady HG, Allen S, Davies MC, Roberts CJ, Tendler SJ, Williams PM. Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase I. Nucleic Acids Res 2003; 31: 4001-4005.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4001-4005
    • Abdelhady, H.G.1    Allen, S.2    Davies, M.C.3    Roberts, C.J.4    Tendler, S.J.5    Williams, P.M.6
  • 29
    • 0037301583 scopus 로고    scopus 로고
    • Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver
    • Morimoto K, Nishikawa M, Kawakami S, et al. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Mol Ther 2003; 7: 254-261.
    • (2003) Mol Ther , vol.7 , pp. 254-261
    • Morimoto, K.1    Nishikawa, M.2    Kawakami, S.3
  • 30
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris M, Steinlein P, Kursa M, Mechtler K, Kircheis R, Wagner E. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther 1998; 5: 1425-1433.
    • (1998) Gene Ther , vol.5 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6
  • 32
    • 0032571392 scopus 로고    scopus 로고
    • Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard H, Remy JS, Loussouarn G, Demolombe S, Behr JP, Escande D. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 1998; 273: 7507-7511.
    • (1998) J Biol Chem , vol.273 , pp. 7507-7511
    • Pollard, H.1    Remy, J.S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.P.5    Escande, D.6
  • 33
    • 0029856329 scopus 로고    scopus 로고
    • Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
    • Zelphati O, Szoka FC Jr. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids. Pharm Res 1996; 13: 1367-1372.
    • (1996) Pharm Res , vol.13 , pp. 1367-1372
    • Zelphati, O.1    Szoka Jr., F.C.2
  • 34
    • 0034607160 scopus 로고    scopus 로고
    • Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery
    • Schaffer DV, Fidelman NA, Dan N, Lauffenburger DA. Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery. Biotechnol Bioeng 2000; 67: 598-606.
    • (2000) Biotechnol Bioeng , vol.67 , pp. 598-606
    • Schaffer, D.V.1    Fidelman, N.A.2    Dan, N.3    Lauffenburger, D.A.4
  • 35
    • 33746281679 scopus 로고    scopus 로고
    • The transport of nanosized gene carriers unraveled by live-cell imaging
    • Bausinger R, von Gersdorff K, Braeckmans K, et al. The transport of nanosized gene carriers unraveled by live-cell imaging. Angew Chem Int Ed Engl 2006; 45: 1568 -1572.
    • (2006) Angew Chem Int Ed Engl , vol.45 , pp. 1568-1572
    • Bausinger, R.1    von Gersdorff, K.2    Braeckmans, K.3
  • 36
    • 14644433029 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle
    • Lee ES, Na K, Bae YH. Super pH-sensitive multifunctional polymeric micelle. Nano Lett 2005; 5: 325-329.
    • (2005) Nano Lett , vol.5 , pp. 325-329
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 37
    • 0043261498 scopus 로고    scopus 로고
    • Pegylation: Engineering improved biopharmaceuticals for oncology
    • Molineux G. Pegylation: engineering improved biopharmaceuticals for oncology. Pharmacotherapy 2003; 23: 3S-8S.
    • (2003) Pharmacotherapy , vol.23
    • Molineux, G.1


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