The transport of nanosized gene carriers unraveled by live-cell imaging

Angewandte Chemie - International Edition

Volumn 45, Issue 10, 2006, Pages 1568-1572

  Bausinger, Ralf ^a   Von Gersdorff, Katharina ^a   Braeckmans, Kevin ^a,b   Ogris, Manfred ^a   Wagner, Ernst ^a   Bräuchle, Christoph ^a   Zumbusch, Andreas ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

DNA; Fluorescence microscopy; Gene expression; Intracellular transport; Nanoparticles

Indexed keywords

CYTOSKELETON; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; INTRACELLULAR TRANSPORT; NONVIRAL VECTORS; POLYPLEXES;

CELLS; CYTOLOGY; DNA; FLUORESCENCE; GENES; NANOSTRUCTURED MATERIALS; SYNTHESIS (CHEMICAL);

MEDICAL IMAGING;

DNA; NANOMATERIAL;

ARTICLE; CELL SURVIVAL; CHEMISTRY; DIFFUSION; GENE TRANSFER; HUMAN; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL SURVIVAL; DIFFUSION; DNA; GENE TRANSFER TECHNIQUES; HUMANS; NANOSTRUCTURES;

EID: 33746281679     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200503021     Document Type: Article

References (18)

1. E. Wagner, Pharm. Res. 2004, 21, 8.
2. O. Boussif, F. Lezoualc'h, M. A. Zanta, M. D. Mergny, D. Scherman, B. Demeneix, J.-P. Behr, Proc. Natl. Acad. Sci. USA 1995, 92, 7297.
3. K. A. Mislick, J. D. Baldeschwieler, Proc. Natl. Acad. Sci. USA 1996, 93, 12 349.
4. I. Kopatz, J. S. Remy, J.-P. Behr, J. Gene Med. 2004, 6, 769.
5. G. S. Harms, L. Cognet, P. H. M. Lommerse, G. A. Blab, H. Kahr, R. Gamsjäger, H. P. Spaink, N. M. Soldatov, C. Romanin, T. Schmidt, Biophys. J. 2001, 81, 2639.
6. G. Seisenberger, M. U. Ried, T. Endreß, H. Büning, M. Hallek, C. Bräuchle, Science 2001, 294, 1929.
7. M. Lakadamyali, M. J. Rust, H. P. Babcock, X. Zhuang, Proc. Natl. Acad. Sci. USA 2003, 100, 9280.
8. J. Suh, D. Wirtz, J. Hanes, Proc. Natl. Acad. Sci. USA 2003, 100, 3878.
9. M. P. Sheetz, S. Turney, H. Qian, E. L. Elson, Nature 1989, 340, 284.
10. A. Caspi, O. Yeger, I. Grosheva, A. D. Bershadsky, M. A. Elbaum, Biophys. J. 2001, 81, 1990.
11. S. J. King, T. A. Schroer, Nat. Cell Biol. 2000, 2, 20.
12. M. Suomalainen, M. Y. Nakano, S. Keller, K. Boucke, R. P. Stidwill, U. F. Greber, J. Cell Biol. 1999, 144, 657.
13. W. T. Godbey, K. K. Wu, A. G. Mikos, Proc. Natl. Acad. Sci. USA 1999, 96, 5177.
14. S. Brunner, E. Fürtbauer, T. Sauer, M. Kursa, E. Wagner, Mol. Ther. 2002, 5, 80.
15. K. von Gersdorff, M. Ogris, E. Wagner, Eur. J. Pharm. Biopharm. 2005, 60, 279.
16. G. F. Walker, C. Fella, J. Pelisek, J. Fahrmeir, S. Boeckle, M. Ogris, E. Wagner, Mol. Ther. 2005, 11, 418.
17. M. J. Saxton, K. Jacobson, Annu. Rev. Biophys. Biomol. Struct. 1997, 26, 373.
18. H. Qian, M. P. Sheetz, E. L. Elson, Biophys. J. 1991, 60, 910.