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Volumn 147, Issue 3, 2007, Pages 564-572

Activated signal transducer and activator of transcription-3 (STAT3) is a poor regulator of tumour necrosis factor-α production by human monocytes

Author keywords

Adenovirus; IL 10; Lipopolysaccharide; NF B; SOCS3

Indexed keywords

ADENOVIRUS VECTOR; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846837317     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2006.03291.x     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 23844483446 scopus 로고    scopus 로고
    • Stat3 in resident macrophages as a repressor protein of inflammatory response
    • Matsukawa A, Kudo S, Maeda T et al. Stat3 in resident macrophages as a repressor protein of inflammatory response. J Immunol 2005; 175:3354-9.
    • (2005) J Immunol , vol.175 , pp. 3354-3359
    • Matsukawa, A.1    Kudo, S.2    Maeda, T.3
  • 2
    • 0345447576 scopus 로고    scopus 로고
    • Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils
    • Matsukawa A, Takeda K, Kudo S, Maeda T, Kagayama M, Akira S. Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils. J Immunol 2003; 171:6198-205.
    • (2003) J Immunol , vol.171 , pp. 6198-6205
    • Matsukawa, A.1    Takeda, K.2    Kudo, S.3    Maeda, T.4    Kagayama, M.5    Akira, S.6
  • 3
    • 28644445445 scopus 로고    scopus 로고
    • Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
    • Kortylewski M, Kujawski M, Wang T et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 2005; 11:1314-21.
    • (2005) Nat Med , vol.11 , pp. 1314-1321
    • Kortylewski, M.1    Kujawski, M.2    Wang, T.3
  • 4
    • 25444444988 scopus 로고    scopus 로고
    • Activation of dendritic cells via inhibition of Jak2/STAT3 signaling
    • Nefedova Y, Cheng P, Gilkes D et al. Activation of dendritic cells via inhibition of Jak2/STAT3 signaling. J Immunol 2005; 175:4338-46.
    • (2005) J Immunol , vol.175 , pp. 4338-4346
    • Nefedova, Y.1    Cheng, P.2    Gilkes, D.3
  • 5
    • 0028172869 scopus 로고
    • Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors
    • Finco TS, Beg AA, Baldwin AS Jr. Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proc Natl Acad Sci USA 1994; 91:11884-8.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11884-11888
    • Finco, T.S.1    Beg, A.A.2    Baldwin Jr., A.S.3
  • 6
    • 0029670083 scopus 로고    scopus 로고
    • Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation
    • DiDonato J, Mercurio F, Rosette C et al. Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation. Mol Cell Biol 1996; 16:1295-304.
    • (1996) Mol Cell Biol , vol.16 , pp. 1295-1304
    • DiDonato, J.1    Mercurio, F.2    Rosette, C.3
  • 7
    • 0028986075 scopus 로고
    • Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
    • Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 1995; 267:1485-8.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 8
    • 1542349094 scopus 로고    scopus 로고
    • The STAT3 DNA-binding domain mediates interaction with NF-kappaB p65 and inducible nitric oxide synthase transrepression in mesangial cells
    • Yu Z, Kone BC. The STAT3 DNA-binding domain mediates interaction with NF-kappaB p65 and inducible nitric oxide synthase transrepression in mesangial cells. J Am Soc Nephrol 2004; 15:585-91.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 585-591
    • Yu, Z.1    Kone, B.C.2
  • 9
    • 0037452789 scopus 로고    scopus 로고
    • STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
    • Welte T, Zhang SS, Wang T et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci USA 2003; 100:1879-84.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1879-1884
    • Welte, T.1    Zhang, S.S.2    Wang, T.3
  • 10
    • 0033527549 scopus 로고    scopus 로고
    • Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
    • Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS Jr. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J Biol Chem 1999; 274:31868-74.
    • (1999) J Biol Chem , vol.274 , pp. 31868-31874
    • Schottelius, A.J.1    Mayo, M.W.2    Sartor, R.B.3    Baldwin Jr., A.S.4
  • 11
    • 33744920357 scopus 로고    scopus 로고
    • Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation
    • Ho HH, Ivashkiv LB. Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation. J Biol Chem 2006; 281:14111-8.
    • (2006) J Biol Chem , vol.281 , pp. 14111-14118
    • HH, H.1    Ivashkiv, L.B.2
  • 13
    • 0036721716 scopus 로고    scopus 로고
    • Shaping gene expression in activated and resting primary macrophages by IL-10
    • Lang R, Patel D, Morris JJ, Rutschman RL, Murray PJ. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol 2002; 169:2253-63.
    • (2002) J Immunol , vol.169 , pp. 2253-2263
    • Lang, R.1    Patel, D.2    Morris, J.J.3    Rutschman, R.L.4    Murray, P.J.5
  • 14
    • 0346103717 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
    • Williams L, Bradley L, Smith A, Foxwell B. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J Immunol 2004; 172:567-76.
    • (2004) J Immunol , vol.172 , pp. 567-576
    • Williams, L.1    Bradley, L.2    Smith, A.3    Foxwell, B.4
  • 15
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • Takeda K, Clausen BE, Kaisho T et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 1999; 10:39-49.
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3
  • 16
    • 0033523019 scopus 로고    scopus 로고
    • Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
    • Riley JK, Takeda K, Akira S, Schreiber RD. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J Biol Chem 1999; 274:16513-21.
    • (1999) J Biol Chem , vol.274 , pp. 16513-16521
    • Riley, J.K.1    Takeda, K.2    Akira, S.3    Schreiber, R.D.4
  • 17
    • 8144226985 scopus 로고    scopus 로고
    • Interleukin-10 suppression of myeloid cell activation - a continuing puzzle
    • Williams LM, Ricchetti G, Sarma U, Smallie T, Foxwell BM. Interleukin-10 suppression of myeloid cell activation - a continuing puzzle. Immunology 2004; 113:281-92.
    • (2004) Immunology , vol.113 , pp. 281-292
    • Williams, L.M.1    Ricchetti, G.2    Sarma, U.3    Smallie, T.4    Foxwell, B.M.5
  • 18
    • 14844352488 scopus 로고    scopus 로고
    • IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages
    • Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY. IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. J Immunol 2005; 174:3148-52.
    • (2005) J Immunol , vol.174 , pp. 3148-3152
    • Butcher, B.A.1    Kim, L.2    Panopoulos, A.D.3    Watowich, S.S.4    Murray, P.J.5    Denkers, E.Y.6
  • 19
    • 8944251628 scopus 로고    scopus 로고
    • A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells
    • Nakajima K, Yamanaka Y, Nakae K et al. A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J 1996; 15:3651-8.
    • (1996) EMBO J , vol.15 , pp. 3651-3658
    • Nakajima, K.1    Yamanaka, Y.2    Nakae, K.3
  • 20
    • 0000999931 scopus 로고
    • Potential antiinflammatory effects of interleukin 4. suppression of humanmonocyte tumor necrosis factor alpha, interleukin 1, and prostaglandin E2
    • Hart PH, Vitti GF, Burgess DR, Whitty GA, Piccoli DS, Hamilton JA. Potential antiinflammatory effects of interleukin 4. suppression of humanmonocyte tumor necrosis factor alpha, interleukin 1, and prostaglandin E2. Proc Natl Acad Sci USA 1989; 86:3803-7.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3803-3807
    • Hart, P.H.1    Vitti, G.F.2    Burgess, D.R.3    Whitty, G.A.4    Piccoli, D.S.5    Hamilton, J.A.6
  • 21
    • 0142071153 scopus 로고    scopus 로고
    • Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection
    • Mayne GC, Borowicz RA, Greeneklee KV, Finlay-Jones JJ, Williams KA, Hart PH. Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection. J Immunol Meth 2003; 278:45-56.
    • (2003) J Immunol Meth , vol.278 , pp. 45-56
    • Mayne, G.C.1    Borowicz, R.A.2    Greeneklee, K.V.3    Finlay-Jones, J.J.4    Williams, K.A.5    Hart, P.H.6
  • 22
    • 0032493278 scopus 로고    scopus 로고
    • Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent
    • Foxwell B, Browne K, Bondeson J et al. Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent. Proc Natl Acad Sci USA 1998; 95:8211-15.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8211-8215
    • Foxwell, B.1    Browne, K.2    Bondeson, J.3
  • 23
    • 0028987384 scopus 로고
    • Upregulation of integrins alpha v beta 3 and alpha v beta 5 on humanmonocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
    • Huang S, Endo RI, Nemerow GR. Upregulation of integrins alpha v beta 3 and alpha v beta 5 on humanmonocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J Virol 1995; 69:2257-63.
    • (1995) J Virol , vol.69 , pp. 2257-2263
    • Huang, S.1    Endo, R.I.2    Nemerow, G.R.3
  • 24
    • 4644261307 scopus 로고    scopus 로고
    • The STAT3 isoforms alpha and beta have unique and specific functions
    • Maritano D, Sugrue ML, Tininini S et al. The STAT3 isoforms alpha and beta have unique and specific functions. Nat Immunol 2004; 5:401-9.
    • (2004) Nat Immunol , vol.5 , pp. 401-409
    • Maritano, D.1    Sugrue, M.L.2    Tininini, S.3
  • 25
    • 0032481383 scopus 로고    scopus 로고
    • IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms. evidence for Stat3-dependent and -independent pathways
    • O'Farrell AM, Liu Y, Moore KW, Mui AL. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms. evidence for Stat3-dependent and -independent pathways. EMBO J 1998; 17:1006-18.
    • (1998) EMBO J , vol.17 , pp. 1006-1018
    • O'Farrell, A.M.1    Liu, Y.2    Moore, K.W.3    Mui, A.L.4
  • 26
    • 33746867115 scopus 로고    scopus 로고
    • Suppressor of cytokine signalling-3 at pathological levels does not regulate lipopolysaccharide or interleukin-10 control of tumour necrosis factor-alpha production by human monocytes
    • Prele CM, Keith-Magee AL, Yerkovich ST, Murcha M, Hart PH. Suppressor of cytokine signalling-3 at pathological levels does not regulate lipopolysaccharide or interleukin-10 control of tumour necrosis factor-alpha production by human monocytes. Immunology 2006; 119:8-17.
    • (2006) Immunology , vol.119 , pp. 8-17
    • Prele, C.M.1    Keith-Magee, A.L.2    Yerkovich, S.T.3    Murcha, M.4    Hart, P.H.5
  • 27
    • 4344568740 scopus 로고    scopus 로고
    • Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression
    • Carl VS, Gautam JK, Comeau LD, Smith MF Jr. Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression. J Leukoc Biol 2004; 76:735-42.
    • (2004) J Leukoc Biol , vol.76 , pp. 735-742
    • Carl, V.S.1    Gautam, J.K.2    Comeau, L.D.3    Smith Jr, M.F.4
  • 28
    • 0032526338 scopus 로고    scopus 로고
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10
    • Aste-Amezaga M, Ma X, Sartori A, Trinchieri G. Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J Immunol 1998; 160:5936-44.
    • (1998) J Immunol , vol.160 , pp. 5936-5944
    • Aste-Amezaga, M.1    Ma, X.2    Sartori, A.3    Trinchieri, G.4
  • 29
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10
    • Bogdan C, Paik J, Vodovotz Y, Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 1992; 267:23301-8.
    • (1992) J Biol Chem , vol.267 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 30
    • 0037310860 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses
    • Ding Y, Chen D, Tarcsafalvi A, Su R, Qin L, Bromberg JS. Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses. J Immunol 2003; 170:1383-91.
    • (2003) J Immunol , vol.170 , pp. 1383-1391
    • Ding, Y.1    Chen, D.2    Tarcsafalvi, A.3    Su, R.4    Qin, L.5    Bromberg, J.S.6
  • 31
    • 0038614944 scopus 로고    scopus 로고
    • SOCS3 regulates the plasticity of gp130 signaling
    • Lang R, Pauleau AL, Parganas E et al. SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol 2003; 4:546-50.
    • (2003) Nat Immunol , vol.4 , pp. 546-550
    • Lang, R.1    Pauleau, A.L.2    Parganas, E.3
  • 32
    • 0037443661 scopus 로고    scopus 로고
    • Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
    • Niemand C, Nimmesgern A, Haan S et al. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003; 170:3263-72.
    • (2003) J Immunol , vol.170 , pp. 3263-3272
    • Niemand, C.1    Nimmesgern, A.2    Haan, S.3
  • 33
    • 0037097509 scopus 로고    scopus 로고
    • Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation
    • Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, Bazzoni F. Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol 2002; 168:6404-11.
    • (2002) J Immunol , vol.168 , pp. 6404-6411
    • Berlato, C.1    Cassatella, M.A.2    Kinjyo, I.3    Gatto, L.4    Yoshimura, A.5    Bazzoni, F.6
  • 34
    • 33646581368 scopus 로고    scopus 로고
    • Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages
    • Qasimi P, Ming-Lum A, Ghanipour A et al. Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. J Biol Chem 2006; 281:6316-24.
    • (2006) J Biol Chem , vol.281 , pp. 6316-6324
    • Qasimi, P.1    Ming-Lum, A.2    Ghanipour, A.3
  • 35
    • 0037600741 scopus 로고    scopus 로고
    • IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
    • Yasukawa H, Ohishi M, Mori H et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol 2003; 4:551-6.
    • (2003) Nat Immunol , vol.4 , pp. 551-556
    • Yasukawa, H.1    Ohishi, M.2    Mori, H.3


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