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Volumn 174, Issue 6, 2005, Pages 3148-3152

Cutting edge: IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-α in host macrophages

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; DNA BINDING PROTEIN; INTERLEUKIN 6; STAT3 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

EID: 14844352488     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.6.3148     Document Type: Article
Times cited : (134)

References (32)
  • 1
    • 0035881856 scopus 로고    scopus 로고
    • Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NFκB
    • Butcher, B. A., L. Kim, P. F. Johnson, and E. Y. Denkers. 2001. Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NFκB. J. Immunol. 167:2193.
    • (2001) J. Immunol. , vol.167 , pp. 2193
    • Butcher, B.A.1    Kim, L.2    Johnson, P.F.3    Denkers, E.Y.4
  • 2
    • 0038643779 scopus 로고    scopus 로고
    • Reduced expression of the inducibie nitric oxide synthase after infection with Toxoplasma gondii facilitates parasite replication in activated murine macrophages
    • Luder, C. G. K., M. Algner, C. Lang, N. Bleicher, and U. Gross. 2003. Reduced expression of the inducibie nitric oxide synthase after infection with Toxoplasma gondii facilitates parasite replication in activated murine macrophages. Int. J. Parasitol. 33:833.
    • (2003) Int. J. Parasitol. , vol.33 , pp. 833
    • Luder, C.G.K.1    Algner, M.2    Lang, C.3    Bleicher, N.4    Gross, U.5
  • 3
    • 0037303310 scopus 로고    scopus 로고
    • In the belly of the beast: Subversion of macrophage proinflammatory signaling cascades during Toxoplasma gondii infection. Cell
    • Denkers, E. Y., L. Kim, and B. A. Butcher. 2003. In the belly of the beast: subversion of macrophage proinflammatory signaling cascades during Toxoplasma gondii infection. Cell. Microbiol. 5:75.
    • (2003) Microbiol. , vol.5 , pp. 75
    • Denkers, E.Y.1    Kim, L.2    Butcher, B.A.3
  • 4
    • 0036716776 scopus 로고    scopus 로고
    • Mechanism of entry determines ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production
    • Butcher, B. A., and E. Y. Denkers. 2002. Mechanism of entry determines ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infect. Immun. 70:5216.
    • (2002) Infect. Immun. , vol.70 , pp. 5216
    • Butcher, B.A.1    Denkers, E.Y.2
  • 6
    • 0343867201 scopus 로고    scopus 로고
    • Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1α
    • Luder, C. G. K., W. Walter, B. Beuerle, M. J. Maeurer, and U. Gross. 2001. Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1α. Eur. J. Immunol. 31:1475.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1475
    • Luder, C.G.K.1    Walter, W.2    Beuerle, B.3    Maeurer, M.J.4    Gross, U.5
  • 7
    • 1342324679 scopus 로고    scopus 로고
    • Toxoplasma gondii interferes wich lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance
    • Kim, L., B. A. Butcher, and E. Y. Denkers. 2004. Toxoplasma gondii interferes wich lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. J. Immunol. 172:3003.
    • (2004) J. Immunol. , vol.172 , pp. 3003
    • Kim, L.1    Butcher, B.A.2    Denkers, E.Y.3
  • 8
    • 0032779561 scopus 로고    scopus 로고
    • The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes
    • Donnelly, R. P., H. Dickensheets, and D. S. Finbloom. 1999. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J. Interferon Cytokine Res. 19:563.
    • (1999) J. Interferon Cytokine Res. , vol.19 , pp. 563
    • Donnelly, R.P.1    Dickensheets, H.2    Finbloom, D.S.3
  • 10
    • 0347624595 scopus 로고    scopus 로고
    • Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation
    • Shen, Y., K. Schlessinger, X. Zhu, E. Meffre, F. Quimby, D. E. Levy, and J. E. Darnell. 2004. Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. Mol. Cell. Biol. 24:407.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 407
    • Shen, Y.1    Schlessinger, K.2    Zhu, X.3    Meffre, E.4    Quimby, F.5    Levy, D.E.6    Darnell, J.E.7
  • 11
    • 0036721716 scopus 로고    scopus 로고
    • Shaping gene expression in activated and resting primary macrophages by IL-10
    • Lang, R., D. Patel, J. J. Morris, R. L. Rutschman, and P. J. Murray. 2002. Shaping gene expression in activated and resting primary macrophages by IL-10. J. Immunol. 169:2253.
    • (2002) J. Immunol. , vol.169 , pp. 2253
    • Lang, R.1    Patel, D.2    Morris, J.J.3    Rutschman, R.L.4    Murray, P.J.5
  • 12
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of stat3 in macrophages and neutrophils
    • Takeda, K., B. E. Clausen, T. Kaisho, T. Tsujimura, N. Terada, I. Forster, and S. Aldra. 1999. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of stat3 in macrophages and neutrophils. Immunity 10:39.
    • (1999) Immunity , vol.10 , pp. 39
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3    Tsujimura, T.4    Terada, N.5    Forster, I.6    Aldra, S.7
  • 13
    • 0346103717 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
    • Williams, L., L. Bradley, A. Smith, and B. Foxwell. 2004. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J. Immunol. 172:567.
    • (2004) J. Immunol. , vol.172 , pp. 567
    • Williams, L.1    Bradley, L.2    Smith, A.3    Foxwell, B.4
  • 14
    • 0035911253 scopus 로고    scopus 로고
    • Conditional vascular cell adhesion molecule 1 deletion in mice: Impaired lymphocyte migration to bone marrow
    • Koni, P. A., S. K. Joshi, U.-A. Temann, D. Olson, L. Burkly, and R. A. Flavell. 2001. Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow. J. Exp. Med. 193:741.
    • (2001) J. Exp. Med. , vol.193 , pp. 741
    • Koni, P.A.1    Joshi, S.K.2    Temann, U.-A.3    Olson, D.4    Burkly, L.5    Flavell, R.A.6
  • 15
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda, K., T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. 1998. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J. Immunol. 161:4652.
    • (1998) J. Immunol. , vol.161 , pp. 4652
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 16
    • 2442666530 scopus 로고    scopus 로고
    • Toxoplasma gondii triggers MyD88-dependent and CCL2(MCP-1) responses using distinct parasite molecules and host receptors
    • Del Rio, L., B. A. Butcher, S. Bennouna, S. Hieny, A. Sher, and E. Y. Denkers. 2004. Toxoplasma gondii triggers MyD88-dependent and CCL2(MCP-1) responses using distinct parasite molecules and host receptors. J. Immunol. 172:6954.
    • (2004) J. Immunol. , vol.172 , pp. 6954
    • Del Rio, L.1    Butcher, B.A.2    Bennouna, S.3    Hieny, S.4    Sher, A.5    Denkers, E.Y.6
  • 17
    • 0037097509 scopus 로고    scopus 로고
    • Involvement of suppressor of cytokine synthesis signaling-3 as a mediator of the inhibitory effects of 1L-10 on lipopolysaccharide-induced macrophage activation
    • Berlato, C., M. A. Cassatella, I. Kinjyo, L. Gatto, A. Yoshimura, and F. Bazzoni. 2002. Involvement of suppressor of cytokine synthesis signaling-3 as a mediator of the inhibitory effects of 1L-10 on lipopolysaccharide-induced macrophage activation. J. Immunol. 168:6404.
    • (2002) J. Immunol. , vol.168 , pp. 6404
    • Berlato, C.1    Cassatella, M.A.2    Kinjyo, I.3    Gatto, L.4    Yoshimura, A.5    Bazzoni, F.6
  • 22
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu, C. L., D. J. Meyer, G. S. Campbell, A. C. Larner, C. Carter-Su, J. Schwartz, and R. Jove. 1995. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269:81.
    • (1995) Science , vol.269 , pp. 81
    • Yu, C.L.1    Meyer, D.J.2    Campbell, G.S.3    Larner, A.C.4    Carter-Su, C.5    Schwartz, J.6    Jove, R.7
  • 24
    • 0031278412 scopus 로고    scopus 로고
    • Intracellular face of vacuoles containing Toxoplasma gondii is determined at the time of formation and depends upon the mechanism of entry
    • Mordue, D. G., and L. D. Sibley. 1997. Intracellular face of vacuoles containing Toxoplasma gondii is determined at the time of formation and depends upon the mechanism of entry. J. Immunol. 159:4452.
    • (1997) J. Immunol. , vol.159 , pp. 4452
    • Mordue, D.G.1    Sibley, L.D.2
  • 25
    • 0030956863 scopus 로고    scopus 로고
    • Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts
    • Carruthers, V. B., and L. D. Sibley. 1997. Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts. Eur. J. Cell Biol. 73:114.
    • (1997) Eur. J. Cell Biol. , vol.73 , pp. 114
    • Carruthers, V.B.1    Sibley, L.D.2
  • 26
    • 0032526338 scopus 로고    scopus 로고
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10
    • Aste-Amezaga, M., X. Ma, A. Sartori, and G. Trinchieri. 1998. Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J. Immunol. 160:5936.
    • (1998) J. Immunol. , vol.160 , pp. 5936
    • Aste-Amezaga, M.1    Ma, X.2    Sartori, A.3    Trinchieri, G.4
  • 29
    • 0033527549 scopus 로고    scopus 로고
    • Interleukin-10 signaling blocks inhibitor of κB kinase activity and nuclear factor κB DNA binding
    • Schottelius, A. J., M. W. Mayo, R. B. Sartor, and A. S. Baldwin. 1999. Interleukin-10 signaling blocks inhibitor of κB kinase activity and nuclear factor κB DNA binding. J. Biol. Chem. 274:31868.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31868
    • Schottelius, A.J.1    Mayo, M.W.2    Sartor, R.B.3    Baldwin, A.S.4
  • 30
    • 4043119714 scopus 로고    scopus 로고
    • Functional inactivation of immature dendritic cells by the inctacellular protozoan Toxoplasma gondii
    • McKee, A. S., F. Dzierszinski, M. Boes, D. S. Roos, and E. J. Pearce. 2004. Functional inactivation of immature dendritic cells by the inctacellular protozoan Toxoplasma gondii. J. Immunol. 173:2632.
    • (2004) J. Immunol. , vol.173 , pp. 2632
    • McKee, A.S.1    Dzierszinski, F.2    Boes, M.3    Roos, D.S.4    Pearce, E.J.5
  • 31
    • 0034766428 scopus 로고    scopus 로고
    • Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expression
    • Goebel, S., U. Gross, and C. G. K. Luder. 2001. Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expression. J. Cell Sci. 114:3495.
    • (2001) J. Cell Sci. , vol.114 , pp. 3495
    • Goebel, S.1    Gross, U.2    Luder, C.G.K.3
  • 32
    • 0032519416 scopus 로고    scopus 로고
    • Toxoplasma gondii-infected cells are resistant to multiple inducers of apoptosis
    • Nash, P. B., M. B. Purner, R. P. Leon, P. Clarke, R. C. Duke, and T. J. Curiel. 1998. Toxoplasma gondii-infected cells are resistant to multiple inducers of apoptosis. J. Immunol. 160:1824.
    • (1998) J. Immunol. , vol.160 , pp. 1824
    • Nash, P.B.1    Purner, M.B.2    Leon, R.P.3    Clarke, P.4    Duke, R.C.5    Curiel, T.J.6


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