-
1
-
-
0024408824
-
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170:2081-95.
-
(1989)
J Exp Med
, vol.170
, pp. 2081-2095
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
2
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10- deficient mice develop chronic enterocolitis. Cell 1993; 75:263-74.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
3
-
-
0033948508
-
Lessons from genetically engineered animal models. XII. IL-10-deficient IL-10 (-/-) mice and intestinal inflammation
-
Rennick DM, Fort MM. Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10 (-/-) mice and intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 2000; 278:G829-33.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.278
-
-
Rennick, D.M.1
Fort, M.M.2
-
4
-
-
0038283161
-
Interleukin-10 therapy - Review of a new approach
-
Asadullah K, Sterry W, Volk HD. Interleukin-10 therapy - review of a new approach. Pharmacol Rev 2003; 55:241-69.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 241-269
-
-
Asadullah, K.1
Sterry, W.2
Volk, H.D.3
-
5
-
-
14644414825
-
New insights into the molecular mechanism of interleukin-10-mediated immunosuppression
-
Grutz G. New insights into the molecular mechanism of interleukin-10-mediated immunosuppression. J Leukoc Biol 2005; 77:3-15.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 3-15
-
-
Grutz, G.1
-
6
-
-
0035898647
-
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology
-
Kontoyiannis D, Kotlyarov A, Carballo E et al. Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J 2001; 20:3760-70.
-
(2001)
EMBO J
, vol.20
, pp. 3760-3770
-
-
Kontoyiannis, D.1
Kotlyarov, A.2
Carballo, E.3
-
7
-
-
0037093989
-
Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages
-
Denys A, Udalova IA, Smith C et al. Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages. J Immunol 2002; 168:4837-45.
-
(2002)
J Immunol
, vol.168
, pp. 4837-4845
-
-
Denys, A.1
Udalova, I.A.2
Smith, C.3
-
8
-
-
20844434815
-
The primary mechanism of the IL-10-regulated anti-inflammatory response is to selectively inhibit transcription
-
Murray PJ. The primary mechanism of the IL-10-regulated anti-inflammatory response is to selectively inhibit transcription. Proc Natl Acad Sci USA 2005; 102:8686-91.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8686-8691
-
-
Murray, P.J.1
-
9
-
-
0036721716
-
Shaping gene expression in activated and resting primary macrophages by IL-10
-
Lang R, Patel D, Morris JJ, Rutschman RL, Murray PJ. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol 2002; 169:2253-63.
-
(2002)
J Immunol
, vol.169
, pp. 2253-2263
-
-
Lang, R.1
Patel, D.2
Morris, J.J.3
Rutschman, R.L.4
Murray, P.J.5
-
10
-
-
22644435047
-
Kinetics of IL-10-induced gene expression in human macrophages
-
Antoniv TT, Park-Min KH, Ivashkiv LB. Kinetics of IL-10-induced gene expression in human macrophages. Immunobiology 2005; 210:87-95.
-
(2005)
Immunobiology
, vol.210
, pp. 87-95
-
-
Antoniv, T.T.1
Park-Min, K.H.2
Ivashkiv, L.B.3
-
11
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
Alexander WS, Hilton DJ. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 2004; 22:503-29.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
12
-
-
0037443661
-
Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
-
Niemand C, Nimmesgern A, Haan S, Fischer P, Schaper F, Rossaint R, Heinrich PC, Muller-Newen G. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003; 170:3263-72.
-
(2003)
J Immunol
, vol.170
, pp. 3263-3272
-
-
Niemand, C.1
Nimmesgern, A.2
Haan, S.3
Fischer, P.4
Schaper, F.5
Rossaint, R.6
Heinrich, P.C.7
Muller-Newen, G.8
-
13
-
-
0346103717
-
Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
-
Williams L, Bradley L, Smith A, Foxwell B. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J Immunol 2004; 172:567-76.
-
(2004)
J Immunol
, vol.172
, pp. 567-576
-
-
Williams, L.1
Bradley, L.2
Smith, A.3
Foxwell, B.4
-
14
-
-
0033104946
-
Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1
-
Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly RP, Larner AC, Finbloom DS. Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 1999; 93:1456-63.
-
(1999)
Blood
, vol.93
, pp. 1456-1463
-
-
Ito, S.1
Ansari, P.2
Sakatsume, M.3
Dickensheets, H.4
Vazquez, N.5
Donnelly, R.P.6
Larner, A.C.7
Finbloom, D.S.8
-
15
-
-
0037097509
-
Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation
-
Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, fBazzoni F. Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol 2002; 168:6404-11.
-
(2002)
J Immunol
, vol.168
, pp. 6404-6411
-
-
Berlato, C.1
Cassatella, M.A.2
Kinjyo, I.3
Gatto, L.4
Yoshimura, A.5
Fbazzoni, F.6
-
16
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa H, Ohishi M, Mori H et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol 2003; 4:551-6.
-
(2003)
Nat Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
-
17
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
Lang R, Pauleau AL, Parganas E, Takahashi Y, Mages J, Ihle JN, Rutschman R, Murray PJ. SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol 2003; 4:546-50.
-
(2003)
Nat Immunol
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
Rutschman, R.7
Murray, P.J.8
-
19
-
-
0242433137
-
IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages
-
Kuwata H, Watanabe Y, Miyoshi H, Yamamoto M, Kaisho T, Takeda K, Akira S. IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages. Blood 2003; 102:4123-9.
-
(2003)
Blood
, vol.102
, pp. 4123-4129
-
-
Kuwata, H.1
Watanabe, Y.2
Miyoshi, H.3
Yamamoto, M.4
Kaisho, T.5
Takeda, K.6
Akira, S.7
-
20
-
-
33646581368
-
Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumour necrosis factor α and nitric oxide production by macrophages
-
Qasimi P, Ming-Lum A, Ghanipour A et al. Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumour necrosis factor α and nitric oxide production by macrophages. J Biol Chem 2006; 281:6316-24.
-
(2006)
J Biol Chem
, vol.281
, pp. 6316-6324
-
-
Qasimi, P.1
Ming-Lum, A.2
Ghanipour, A.3
-
21
-
-
0035006109
-
Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
-
Cacalano NA, Sanden D, Johnston JA. Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat Cell Biol 2001; 3:460-5.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 460-465
-
-
Cacalano, N.A.1
Sanden, D.2
Johnston, J.A.3
-
22
-
-
0036681955
-
Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
-
Hortner M, Nielsch U, Mayr LM, Johnston JA, Heinrich PC, Haan S. Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J Immunol 2002; 169:1219-27.
-
(2002)
J Immunol
, vol.169
, pp. 1219-1227
-
-
Hortner, M.1
Nielsch, U.2
Mayr, L.M.3
Johnston, J.A.4
Heinrich, P.C.5
Haan, S.6
-
23
-
-
0142071153
-
Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection
-
Mayne GC, Borowicz RA, Greeneklee KV, Finlay-Jones JJ, Williams KA, Hart PH. Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection. J Immunol Methods 2003; 278:45-56.
-
(2003)
J Immunol Methods
, vol.278
, pp. 45-56
-
-
Mayne, G.C.1
Borowicz, R.A.2
Greeneklee, K.V.3
Finlay-Jones, J.J.4
Williams, K.A.5
Hart, P.H.6
-
24
-
-
0035577641
-
Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR
-
Hamalainen HK, Tubman JC, Vikman S, Kyrola T, Ylikoski E, Warrington JA, Lahesmaa R. Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR. Anal Biochem 2001; 299:63-70.
-
(2001)
Anal Biochem
, vol.299
, pp. 63-70
-
-
Hamalainen, H.K.1
Tubman, J.C.2
Vikman, S.3
Kyrola, T.4
Ylikoski, E.5
Warrington, J.A.6
Lahesmaa, R.7
-
25
-
-
0029118395
-
IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
-
Finbloom DS, Winestock KD. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J Immunol 1995; 155:1079-90.
-
(1995)
J Immunol
, vol.155
, pp. 1079-1090
-
-
Finbloom, D.S.1
Winestock, K.D.2
-
26
-
-
0030947420
-
Interleukin-10 inhibits interferon-gamma-induced intercellular adhesion molecule-1 gene transcription in human monocytes
-
Song S, Ling-Hu H, Roebuck KA, Rabbi MF, Donnelly RP, Finnegan A. Interleukin-10 inhibits interferon-gamma-induced intercellular adhesion molecule-1 gene transcription in human monocytes. Blood 1997; 89:4461-9.
-
(1997)
Blood
, vol.89
, pp. 4461-4469
-
-
Song, S.1
Ling-Hu, H.2
Roebuck, K.A.3
Rabbi, M.F.4
Donnelly, R.P.5
Finnegan, A.6
-
27
-
-
0028365152
-
IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells
-
Wang P, Wu P, Siegel MI, Egan RW, Billah MM. IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol 1994; 153:811-6.
-
(1994)
J Immunol
, vol.153
, pp. 811-816
-
-
Wang, P.1
Wu, P.2
Siegel, M.I.3
Egan, R.W.4
Billah, M.M.5
-
28
-
-
0033104734
-
Cutting edge. clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages
-
Kishore R, Tebo JM, Kolosov M, Hamilton TA. Cutting edge. clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages. J Immunol 1999; 162:2457-61.
-
(1999)
J Immunol
, vol.162
, pp. 2457-2461
-
-
Kishore, R.1
Tebo, J.M.2
Kolosov, M.3
Hamilton, T.A.4
-
29
-
-
23844524089
-
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
-
Jo D, Liu D, Yao S, Collins RD, Hawiger J. Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nat Med 2005; 11:892-8.
-
(2005)
Nat Med
, vol.11
, pp. 892-898
-
-
Jo, D.1
Liu, D.2
Yao, S.3
Collins, R.D.4
Hawiger, J.5
-
30
-
-
11144233242
-
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells
-
Baetz A, Frey M, Heeg K, Dalpke AH. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J Biol Chem 2004; 279:54708-15.
-
(2004)
J Biol Chem
, vol.279
, pp. 54708-54715
-
-
Baetz, A.1
Frey, M.2
Heeg, K.3
Dalpke, A.H.4
-
31
-
-
11144224785
-
Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of Toll-like receptor signaling
-
Gingras S, Parganas E, de Pauw A, Ihle JN, Murray PJ. Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of Toll-like receptor signaling. J Biol Chem 2004; 279:54702-7.
-
(2004)
J Biol Chem
, vol.279
, pp. 54702-54707
-
-
Gingras, S.1
Parganas, E.2
De Pauw, A.3
Ihle, J.N.4
Murray, P.J.5
-
32
-
-
29244442569
-
Suppressor of cytokine signaling 1 regulated the immune response to infection by a unique inhibition of type 1 interferon activity
-
Fenner JE, Starr R, Cornish AL et al. Suppressor of cytokine signaling 1 regulated the immune response to infection by a unique inhibition of type 1 interferon activity. Nat Immunol 2006; 3:33-9.
-
(2006)
Nat Immunol
, vol.3
, pp. 33-39
-
-
Fenner, J.E.1
Starr, R.2
Cornish, A.L.3
-
33
-
-
28044461950
-
Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT
-
Kimura A, Naka T, Muta T, Takeuchi O, Akira S, Kawase I, Kishimoto T. Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. Proc Natl Acad Sci USA 2005; 47:17089-94.
-
(2005)
Proc Natl Acad Sci USA
, vol.47
, pp. 17089-17094
-
-
Kimura, A.1
Naka, T.2
Muta, T.3
Takeuchi, O.4
Akira, S.5
Kawase, I.6
Kishimoto, T.7
-
34
-
-
13044290651
-
Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: Evidence for an IL-10-induced pathway that is independent of STAT protein activation
-
Cassatella MA, Gasperini S, Bovolenta C et al. Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation. Blood 1999; 94:2880-9.
-
(1999)
Blood
, vol.94
, pp. 2880-2889
-
-
Cassatella, M.A.1
Gasperini, S.2
Bovolenta, C.3
-
35
-
-
18244383058
-
The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis
-
Jenkins BJ, Roberts AW, Najdovska M, Grail D, Ernst M. The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis. Blood 2005; 105:3512-20.
-
(2005)
Blood
, vol.105
, pp. 3512-3520
-
-
Jenkins, B.J.1
Roberts, A.W.2
Najdovska, M.3
Grail, D.4
Ernst, M.5
|