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Volumn 18, Issue 3, 2007, Pages 184-195

Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition

Author keywords

Industrial toxins; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis

Indexed keywords

ALPHA TOCOPHEROL; AMIODARONE; BETAINE; METHIONINE; PIOGLITAZONE; S ADENOSYLMETHIONINE; TAMOXIFEN; TETRAHYDROLIPSTATIN; ZINC;

EID: 33846821856     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2006.12.006     Document Type: Article
Times cited : (244)

References (106)
  • 1
    • 0001270375 scopus 로고
    • Liver impairment in the obese
    • Westwater J.O., and Fainer D. Liver impairment in the obese. Gastroenterology 34 4 (1958) 686-693
    • (1958) Gastroenterology , vol.34 , Issue.4 , pp. 686-693
    • Westwater, J.O.1    Fainer, D.2
  • 2
    • 0018686401 scopus 로고
    • Fatty liver hepatitis and cirrhosis in obese patients
    • Adler M., and Schaffner F. Fatty liver hepatitis and cirrhosis in obese patients. Am J Med 67 5 (1979) 811-816
    • (1979) Am J Med , vol.67 , Issue.5 , pp. 811-816
    • Adler, M.1    Schaffner, F.2
  • 3
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J., Viggiano T.R., McGill D.B., and Oh B.J. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 55 7 (1980) 434-438
    • (1980) Mayo Clin Proc , vol.55 , Issue.7 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 4
    • 28844440050 scopus 로고    scopus 로고
    • Decreased serum adiponectin: an early event in pediatric nonalcoholic fatty liver disease
    • Louthan M.V., Joshi-Barve S., and McClain C.J. Decreased serum adiponectin: an early event in pediatric nonalcoholic fatty liver disease. J Pediatr 147 6 (2005) 835-838
    • (2005) J Pediatr , vol.147 , Issue.6 , pp. 835-838
    • Louthan, M.V.1    Joshi-Barve, S.2    McClain, C.J.3
  • 6
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri B.A., and Caldwell S.H. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 37 5 (2003) 1202-1219
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 7
    • 8444233581 scopus 로고    scopus 로고
    • Role of liver biopsy in the assessment of non-alcoholic fatty liver disease
    • Hubscher S.G. Role of liver biopsy in the assessment of non-alcoholic fatty liver disease. Eur J Gastroenterol Hepatol 16 11 (2004) 1107-1115
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , Issue.11 , pp. 1107-1115
    • Hubscher, S.G.1
  • 9
    • 33645523067 scopus 로고    scopus 로고
    • Prevalence of overweight and obesity in the United States, 1999-2004
    • Ogden C.L., Carroll M.D., Curtin L.R., McDowell M.A., Tabak C.J., and Flegal K.M. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 295 13 (2006) 1549-1555
    • (2006) JAMA , vol.295 , Issue.13 , pp. 1549-1555
    • Ogden, C.L.1    Carroll, M.D.2    Curtin, L.R.3    McDowell, M.A.4    Tabak, C.J.5    Flegal, K.M.6
  • 10
    • 4644279733 scopus 로고    scopus 로고
    • Increasing prevalence of the metabolic syndrome among U.S. adults
    • Ford E.S., Giles W.H., and Mokdad A.H. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care 27 10 (2004) 2444-2449
    • (2004) Diabetes Care , vol.27 , Issue.10 , pp. 2444-2449
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 11
    • 2142815151 scopus 로고    scopus 로고
    • Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity
    • Bray G.A., Nielsen S.J., and Popkin B.M. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr 79 4 (2004) 537-543
    • (2004) Am J Clin Nutr , vol.79 , Issue.4 , pp. 537-543
    • Bray, G.A.1    Nielsen, S.J.2    Popkin, B.M.3
  • 13
    • 0033014224 scopus 로고    scopus 로고
    • Dietary-fat intake in the US population
    • Kennedy E.T., Bowman S.A., and Powell R. Dietary-fat intake in the US population. J Am Coll Nutr 18 3 (1999) 207-212
    • (1999) J Am Coll Nutr , vol.18 , Issue.3 , pp. 207-212
    • Kennedy, E.T.1    Bowman, S.A.2    Powell, R.3
  • 14
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    • Neuschwander-Tetri B.A., Brunt E.M., Wehmeier K.R., Oliver D., and Bacon B.R. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 38 4 (2003) 1008-10017
    • (2003) Hepatology , vol.38 , Issue.4 , pp. 1008-10017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Oliver, D.4    Bacon, B.R.5
  • 15
    • 0034089687 scopus 로고    scopus 로고
    • Prevalence of abnormal serum aminotransferase values in overweight and obese adolescents
    • Strauss R.S., Barlow S.E., and Dietz W.H. Prevalence of abnormal serum aminotransferase values in overweight and obese adolescents. J Pediatr 136 6 (2000) 727-733
    • (2000) J Pediatr , vol.136 , Issue.6 , pp. 727-733
    • Strauss, R.S.1    Barlow, S.E.2    Dietz, W.H.3
  • 16
    • 0031756933 scopus 로고    scopus 로고
    • A comparative assessment of liver function in workers in the petroleum industry
    • Michailova A., Kuneva T., and Popov T. A comparative assessment of liver function in workers in the petroleum industry. Int Arch Occup Environ Health 71 Suppl (1998) S46-S49
    • (1998) Int Arch Occup Environ Health , vol.71 , Issue.SUPPL
    • Michailova, A.1    Kuneva, T.2    Popov, T.3
  • 18
    • 30144440445 scopus 로고    scopus 로고
    • CASH (chemotherapy-associated steatohepatitis) costs
    • Fong Y., and Bentrem D.J. CASH (chemotherapy-associated steatohepatitis) costs. Ann Surg 243 1 (2006) 8-9
    • (2006) Ann Surg , vol.243 , Issue.1 , pp. 8-9
    • Fong, Y.1    Bentrem, D.J.2
  • 19
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark J.M., Brancati F.L., and Diehl A.M. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 98 5 (2003) 960-967
    • (2003) Am J Gastroenterol , vol.98 , Issue.5 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 20
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    • Browning J.D., Szczepaniak L.S., Dobbins R., Nuremberg P., Horton J.D., Cohen J.C., et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 40 6 (2004) 1387-1395
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3    Nuremberg, P.4    Horton, J.D.5    Cohen, J.C.6
  • 21
    • 4644297019 scopus 로고    scopus 로고
    • Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies
    • Fassio E., Alvarez E., Dominguez N., Landeira G., and Longo C. Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies. Hepatology 40 4 (2004) 820-826
    • (2004) Hepatology , vol.40 , Issue.4 , pp. 820-826
    • Fassio, E.1    Alvarez, E.2    Dominguez, N.3    Landeira, G.4    Longo, C.5
  • 22
    • 0024336332 scopus 로고
    • Nonalcoholic steatohepatitis: a study of 49 patients
    • Lee R.G. Nonalcoholic steatohepatitis: a study of 49 patients. Hum Pathol 20 6 (1989) 594-598
    • (1989) Hum Pathol , vol.20 , Issue.6 , pp. 594-598
    • Lee, R.G.1
  • 23
    • 0036894480 scopus 로고    scopus 로고
    • NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States
    • Marrero J.A., Fontana R.J., Su G.L., Conjeevaram H.S., Emick D.M., and Lok A.S. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 36 6 (2002) 1349-1354
    • (2002) Hepatology , vol.36 , Issue.6 , pp. 1349-1354
    • Marrero, J.A.1    Fontana, R.J.2    Su, G.L.3    Conjeevaram, H.S.4    Emick, D.M.5    Lok, A.S.6
  • 25
    • 33646547644 scopus 로고    scopus 로고
    • Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States
    • Ioannou G.N., Weiss N.S., Boyko E.J., Mozaffarian D., and Lee S.P. Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States. Hepatology 43 5 (2006) 1145-1151
    • (2006) Hepatology , vol.43 , Issue.5 , pp. 1145-1151
    • Ioannou, G.N.1    Weiss, N.S.2    Boyko, E.J.3    Mozaffarian, D.4    Lee, S.P.5
  • 26
    • 28844459409 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: from cell biology to clinical practice
    • Cortez-Pinto H., de Moura M.C., and Day C.P. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol 44 1 (2006) 197-208
    • (2006) J Hepatol , vol.44 , Issue.1 , pp. 197-208
    • Cortez-Pinto, H.1    de Moura, M.C.2    Day, C.P.3
  • 28
    • 0037232972 scopus 로고    scopus 로고
    • Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease
    • Sumida Y., Nakashima T., Yoh T., Furutani M., Hirohama A., Kakisaka Y., et al. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol 38 (2003) 32-38
    • (2003) J Hepatol , vol.38 , pp. 32-38
    • Sumida, Y.1    Nakashima, T.2    Yoh, T.3    Furutani, M.4    Hirohama, A.5    Kakisaka, Y.6
  • 29
    • 0037339931 scopus 로고    scopus 로고
    • Is oxidant stress a connection between obesity and atherosclerosis?
    • Morrow J.D. Is oxidant stress a connection between obesity and atherosclerosis?. Arterioscler Thromb Vasc Biol 23 (2003) 368-370
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 368-370
    • Morrow, J.D.1
  • 30
    • 0041764982 scopus 로고    scopus 로고
    • CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
    • Emery M.G., Fisher J.M., Chien J.Y., Kharasch E.D., Dellinger E.P., Kowdley K.V., et al. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease. Hepatology 38 (2003) 428-435
    • (2003) Hepatology , vol.38 , pp. 428-435
    • Emery, M.G.1    Fisher, J.M.2    Chien, J.Y.3    Kharasch, E.D.4    Dellinger, E.P.5    Kowdley, K.V.6
  • 31
    • 85030434746 scopus 로고    scopus 로고
    • Increased oxidative stress in obesity and its impact on metabolic syndrome
    • Furukawa S., Fujita T., Shimabukuro M., Iwaki M., Yamada Y., Nakajima Y., et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 114 12 (2004) 1752-1761
    • (2004) J Clin Invest , vol.114 , Issue.12 , pp. 1752-1761
    • Furukawa, S.1    Fujita, T.2    Shimabukuro, M.3    Iwaki, M.4    Yamada, Y.5    Nakajima, Y.6
  • 35
    • 0032898080 scopus 로고    scopus 로고
    • Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver
    • Rashid A., Wu T.C., Huang C.C., Chen C.H., Lin H.Z., Yang S.Q., et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. Hepatology 29 4 (1999) 1131-1138
    • (1999) Hepatology , vol.29 , Issue.4 , pp. 1131-1138
    • Rashid, A.1    Wu, T.C.2    Huang, C.C.3    Chen, C.H.4    Lin, H.Z.5    Yang, S.Q.6
  • 36
    • 0033520771 scopus 로고    scopus 로고
    • Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study
    • Cortez-Pinto H., Chatham J., Chacko V.P., Arnold C., Rashid A., and Diehl A.M. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 282 17 (1999) 1659-1664
    • (1999) JAMA , vol.282 , Issue.17 , pp. 1659-1664
    • Cortez-Pinto, H.1    Chatham, J.2    Chacko, V.P.3    Arnold, C.4    Rashid, A.5    Diehl, A.M.6
  • 37
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • McClain C.J., and Cohen D.A. Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 9 (1989) 349-351
    • (1989) Hepatology , vol.9 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 38
    • 4143065802 scopus 로고    scopus 로고
    • Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease
    • McClain C.J., Song Z., Barve S.S., Hill D.B., and Deaciuc I. Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 287 3 (2004) G497-G502
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , Issue.3
    • McClain, C.J.1    Song, Z.2    Barve, S.S.3    Hill, D.B.4    Deaciuc, I.5
  • 39
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H., and Diehl A.M. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 343 (2000) 1467-1476
    • (2000) N Engl J Med , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 40
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis
    • Yang S.Q., Lin H.Z., Lane M.D., Clemens M., and Diehl A.M. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A 94 6 (1997) 2557-2562
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.6 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 41
    • 0030955323 scopus 로고    scopus 로고
    • Choline deficiency augments and antibody to tumor necrosis factor-a attenuates endotoxin-induced hepatic injury
    • Eastin C.E., McClain C.J., Lee E.Y., Bagby G.J., and Chawla R.K. Choline deficiency augments and antibody to tumor necrosis factor-a attenuates endotoxin-induced hepatic injury. Alcohol Clin Exp Res 21 (1997) 1037-1047
    • (1997) Alcohol Clin Exp Res , vol.21 , pp. 1037-1047
    • Eastin, C.E.1    McClain, C.J.2    Lee, E.Y.3    Bagby, G.J.4    Chawla, R.K.5
  • 42
    • 0031830869 scopus 로고    scopus 로고
    • S-adenosylmethionine (AdoMet) deficiency and tumor necrosis factor (TNF) in lipopolysaccharide (LPS) induced hepatic injury
    • Chawla R., Watson W., Eastin C., Lee E., Schmidt J., and McClain C.J. S-adenosylmethionine (AdoMet) deficiency and tumor necrosis factor (TNF) in lipopolysaccharide (LPS) induced hepatic injury. Am J Physiol 275 (1998) G125-G129
    • (1998) Am J Physiol , vol.275
    • Chawla, R.1    Watson, W.2    Eastin, C.3    Lee, E.4    Schmidt, J.5    McClain, C.J.6
  • 43
    • 27744458510 scopus 로고    scopus 로고
    • NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis
    • Dela Pena A., Leclercq I., Field J., George J., Jones B., and Farrell G. NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis. Gastroenterology 129 5 (2005) 1663-1674
    • (2005) Gastroenterology , vol.129 , Issue.5 , pp. 1663-1674
    • Dela Pena, A.1    Leclercq, I.2    Field, J.3    George, J.4    Jones, B.5    Farrell, G.6
  • 44
    • 0042265627 scopus 로고    scopus 로고
    • Cytokines and NASH: effects of lifestyle modification and vitamin E
    • Kugelmas M., Hill D.B., Vivian B., Marsano L., and McClain C.J. Cytokines and NASH: effects of lifestyle modification and vitamin E. Hepatology 38 2 (2003) 413-419
    • (2003) Hepatology , vol.38 , Issue.2 , pp. 413-419
    • Kugelmas, M.1    Hill, D.B.2    Vivian, B.3    Marsano, L.4    McClain, C.J.5
  • 45
    • 0035183475 scopus 로고    scopus 로고
    • Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
    • Crespo J., Cayon A., Fernandez-Gil P., Hernandez-Guerra M., Mayorga M., Dominguez-Diez A., et al. Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology 34 (2001) 1158-1163
    • (2001) Hepatology , vol.34 , pp. 1158-1163
    • Crespo, J.1    Cayon, A.2    Fernandez-Gil, P.3    Hernandez-Guerra, M.4    Mayorga, M.5    Dominguez-Diez, A.6
  • 46
    • 0036165809 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in non-alcoholic fatty liver disease
    • Valenti L., Francanzani L., Dongiovanni P., Santorelli G., Branchi A., Taioli E., et al. Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in non-alcoholic fatty liver disease. Gastroenterology 122 (2002) 274-280
    • (2002) Gastroenterology , vol.122 , pp. 274-280
    • Valenti, L.1    Francanzani, L.2    Dongiovanni, P.3    Santorelli, G.4    Branchi, A.5    Taioli, E.6
  • 47
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg A.H., Combs T.P., Du X., Brownlee M., and Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7 (2001) 947-953
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 48
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M., Suraamornkul S., Piper P., Hardies L.J., Glass L., Cersosimo E., et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 89 (2004) 200-206
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-206
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3    Hardies, L.J.4    Glass, L.5    Cersosimo, E.6
  • 49
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A., Wang Y., Keshaw H., Xu L.Y., Lam K.S., and Cooper G.J. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 112 (2003) 91-100
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 50
    • 10844220730 scopus 로고    scopus 로고
    • Adiponectin and its receptors in non-alcoholic steatohepatitis
    • Kaser S., Moschen A., Cayon A., Kaser A., Crespo J., Pons-Romero F., et al. Adiponectin and its receptors in non-alcoholic steatohepatitis. Gut 54 1 (2005) 117-121
    • (2005) Gut , vol.54 , Issue.1 , pp. 117-121
    • Kaser, S.1    Moschen, A.2    Cayon, A.3    Kaser, A.4    Crespo, J.5    Pons-Romero, F.6
  • 52
    • 0002148519 scopus 로고    scopus 로고
    • S-adenosylmethionine and the liver
    • Arias I.M. (Ed), Raven Press, New York
    • Mato J.M., Alvarez L., and Corrales J. S-adenosylmethionine and the liver. In: Arias I.M. (Ed). Liver: Biology and Pathobiology (1997), Raven Press, New York 461-470
    • (1997) Liver: Biology and Pathobiology , pp. 461-470
    • Mato, J.M.1    Alvarez, L.2    Corrales, J.3
  • 53
    • 0023902956 scopus 로고    scopus 로고
    • S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis
    • Duce A.M., Ortiz P., Cabrero C., and Mato J.M. S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis. Hepatology 8 (1998) 65-68
    • (1998) Hepatology , vol.8 , pp. 65-68
    • Duce, A.M.1    Ortiz, P.2    Cabrero, C.3    Mato, J.M.4
  • 54
    • 0030920140 scopus 로고    scopus 로고
    • S-adenosylmethionine synthesis: molecular mechanisms and clinical implications
    • Mato J.M., Alvarez L., Ortiz P., and Pajares M.A. S-adenosylmethionine synthesis: molecular mechanisms and clinical implications. Pharmacol Ther 73 (1997) 265-280
    • (1997) Pharmacol Ther , vol.73 , pp. 265-280
    • Mato, J.M.1    Alvarez, L.2    Ortiz, P.3    Pajares, M.A.4
  • 56
    • 0035826898 scopus 로고    scopus 로고
    • Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation
    • Lu S.C., Alvarez L., Huang Z.Z., Chen L., An W., Corrales F.J., et al. Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. Proc Natl Acad Sci U S A 98 (2001) 5560-5565
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5560-5565
    • Lu, S.C.1    Alvarez, L.2    Huang, Z.Z.3    Chen, L.4    An, W.5    Corrales, F.J.6
  • 57
    • 4644248469 scopus 로고    scopus 로고
    • S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease
    • Song Z., Zhou Z., Uriarte S., Wang L., Kang Y.J., Chen T., et al. S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease. Hepatology 40 (2004) 989-997
    • (2004) Hepatology , vol.40 , pp. 989-997
    • Song, Z.1    Zhou, Z.2    Uriarte, S.3    Wang, L.4    Kang, Y.J.5    Chen, T.6
  • 58
    • 0037960128 scopus 로고    scopus 로고
    • Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice
    • Ji C., and Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology 124 (2003) 1488-1499
    • (2003) Gastroenterology , vol.124 , pp. 1488-1499
    • Ji, C.1    Kaplowitz, N.2
  • 59
    • 0042920699 scopus 로고    scopus 로고
    • Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats
    • Barak A.J., Beckenhauer H.C., Mailliard M.E., Kharbanda K.K., and Tuma D.J. Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats. J Nutr 133 (2003) 2845-2848
    • (2003) J Nutr , vol.133 , pp. 2845-2848
    • Barak, A.J.1    Beckenhauer, H.C.2    Mailliard, M.E.3    Kharbanda, K.K.4    Tuma, D.J.5
  • 60
    • 0035552975 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences
    • Schwahn B., and Rozen R. Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences. Am J Pharmacogenomics 1 (2001) 189-201
    • (2001) Am J Pharmacogenomics , vol.1 , pp. 189-201
    • Schwahn, B.1    Rozen, R.2
  • 63
    • 0033055916 scopus 로고    scopus 로고
    • Fatty liver - an additional and treatable feature of the insulin resistance syndrome
    • Knobler H., Schattner A., Zhornicki T., Malnick S.D., Keter D., Sokolovskaya N., et al. Fatty liver - an additional and treatable feature of the insulin resistance syndrome. QJM 92 (1999) 73-79
    • (1999) QJM , vol.92 , pp. 73-79
    • Knobler, H.1    Schattner, A.2    Zhornicki, T.3    Malnick, S.D.4    Keter, D.5    Sokolovskaya, N.6
  • 66
    • 33846791359 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease. Gastroenterology board review manual
    • Cave M., Louthan M.V., and McClain C.J. Nonalcoholic fatty liver disease. Gastroenterology board review manual. Hosp Physician 11 1 (2005) 1-12
    • (2005) Hosp Physician , vol.11 , Issue.1 , pp. 1-12
    • Cave, M.1    Louthan, M.V.2    McClain, C.J.3
  • 67
    • 0029583826 scopus 로고
    • Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulin-resistant black men with NIDDM
    • Banerji M.A., Buckley M.C., Chaiken R.L., Gordon D., Lebovitz H.E., and Kral J.G. Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulin-resistant black men with NIDDM. Int J Obes Relat Metab Disord 19 (1995) 846-850
    • (1995) Int J Obes Relat Metab Disord , vol.19 , pp. 846-850
    • Banerji, M.A.1    Buckley, M.C.2    Chaiken, R.L.3    Gordon, D.4    Lebovitz, H.E.5    Kral, J.G.6
  • 68
    • 0342314436 scopus 로고    scopus 로고
    • Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients
    • Ryysy L., Hakkinen A.M., Goto T., Vehkavaara S., Westerbacka J., Halavaara J., et al. Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes 49 (2000) 749-758
    • (2000) Diabetes , vol.49 , pp. 749-758
    • Ryysy, L.1    Hakkinen, A.M.2    Goto, T.3    Vehkavaara, S.4    Westerbacka, J.5    Halavaara, J.6
  • 69
    • 0037567697 scopus 로고    scopus 로고
    • Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes
    • Bajaj M., Suraamornkul S., Pratipanawatr T., Hardies L.J., Pratipanawatr W., Glass L., et al. Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes. Diabetes 52 (2003) 1364-1370
    • (2003) Diabetes , vol.52 , pp. 1364-1370
    • Bajaj, M.1    Suraamornkul, S.2    Pratipanawatr, T.3    Hardies, L.J.4    Pratipanawatr, W.5    Glass, L.6
  • 70
    • 0036310037 scopus 로고    scopus 로고
    • The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
    • Mayerson A.B., Hundal R.S., Dufour S., Lebon V., Befroy D., Cline G.W., et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 51 (2002) 797-802
    • (2002) Diabetes , vol.51 , pp. 797-802
    • Mayerson, A.B.1    Hundal, R.S.2    Dufour, S.3    Lebon, V.4    Befroy, D.5    Cline, G.W.6
  • 71
    • 85054934701 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits"?
    • Day C.P., and James O.F. Steatohepatitis: a tale of two "hits"?. Gastroenterology 16 (1998) 663-678
    • (1998) Gastroenterology , vol.16 , pp. 663-678
    • Day, C.P.1    James, O.F.2
  • 73
    • 0037085471 scopus 로고    scopus 로고
    • Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury
    • Bjorkegren J., Beigneux A., Bergo M.O., and Maher J.J. Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury. J Biol Chem 277 (2002) 5476-5483
    • (2002) J Biol Chem , vol.277 , pp. 5476-5483
    • Bjorkegren, J.1    Beigneux, A.2    Bergo, M.O.3    Maher, J.J.4
  • 75
    • 0020555346 scopus 로고
    • Relationship of body weight to disposition of hexachloronbenzene
    • Rozman T., Rozman K., and Smith G.S. Relationship of body weight to disposition of hexachloronbenzene. Toxicol Lett 18 (1983) 171-175
    • (1983) Toxicol Lett , vol.18 , pp. 171-175
    • Rozman, T.1    Rozman, K.2    Smith, G.S.3
  • 77
    • 2342569765 scopus 로고    scopus 로고
    • Clinical and histopathological features of NASH in workers exposed to chemicals with or without associated metabolis conditions
    • Cotrim H.P., DeFreitas L.A., Freitas C., Braga L., Sopusa R., Carvalho F., et al. Clinical and histopathological features of NASH in workers exposed to chemicals with or without associated metabolis conditions. Liver Int 24 (2004) 131-135
    • (2004) Liver Int , vol.24 , pp. 131-135
    • Cotrim, H.P.1    DeFreitas, L.A.2    Freitas, C.3    Braga, L.4    Sopusa, R.5    Carvalho, F.6
  • 80
    • 20444461959 scopus 로고    scopus 로고
    • The pathophysiology of portal hypertension
    • Treiber G., Cssepregi A., and Malfertheiner P. The pathophysiology of portal hypertension. Dig Dis 23 (2005) 6-10
    • (2005) Dig Dis , vol.23 , pp. 6-10
    • Treiber, G.1    Cssepregi, A.2    Malfertheiner, P.3
  • 81
    • 0022552857 scopus 로고
    • Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity
    • Bidlack W.R., Brown R.C., and Mohan C. Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity. Fed Proc 45 (1986) 142-148
    • (1986) Fed Proc , vol.45 , pp. 142-148
    • Bidlack, W.R.1    Brown, R.C.2    Mohan, C.3
  • 82
    • 0030740659 scopus 로고    scopus 로고
    • Therapeutic effects of restricted diet and exercise in obese patients with fatty liver
    • Ueno T., Sugawara H., Sujaku K., Hashimoto O., Tsuji R., Tamaki S., et al. Therapeutic effects of restricted diet and exercise in obese patients with fatty liver. J Hepatol 27 1 (1997) 103-107
    • (1997) J Hepatol , vol.27 , Issue.1 , pp. 103-107
    • Ueno, T.1    Sugawara, H.2    Sujaku, K.3    Hashimoto, O.4    Tsuji, R.5    Tamaki, S.6
  • 83
    • 0028814439 scopus 로고
    • Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine
    • Pate R.R., Pratt M., Blair S.N., Haskell W.L., Macera C.A., Bouchard C., et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 273 5 (1995) 402-407
    • (1995) JAMA , vol.273 , Issue.5 , pp. 402-407
    • Pate, R.R.1    Pratt, M.2    Blair, S.N.3    Haskell, W.L.4    Macera, C.A.5    Bouchard, C.6
  • 84
    • 32044451685 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass improves liver histology in patients with non-alcoholic fatty liver disease
    • Clark J.M., Alkhuraishi A.R., Solga S.F., Alli P., Diehl A.M., and Magnuson T.H. Roux-en-Y gastric bypass improves liver histology in patients with non-alcoholic fatty liver disease. Obes Res 13 7 (2005) 1180-1186
    • (2005) Obes Res , vol.13 , Issue.7 , pp. 1180-1186
    • Clark, J.M.1    Alkhuraishi, A.R.2    Solga, S.F.3    Alli, P.4    Diehl, A.M.5    Magnuson, T.H.6
  • 85
    • 0025959287 scopus 로고
    • Hepatic effects of dietary weight loss in morbidly obese subjects
    • Andersen T., Gluud C., Franzmann M.B., and Christoffersen P. Hepatic effects of dietary weight loss in morbidly obese subjects. J Hepatol 12 2 (1991) 224-229
    • (1991) J Hepatol , vol.12 , Issue.2 , pp. 224-229
    • Andersen, T.1    Gluud, C.2    Franzmann, M.B.3    Christoffersen, P.4
  • 86
    • 33646882162 scopus 로고    scopus 로고
    • Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study
    • Capanni M., Calella F., Biagini M.R., Genise S., Raimondi L., Bedogni G., et al. Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study. Aliment Pharmacol Ther 23 8 (2006) 1143-1151
    • (2006) Aliment Pharmacol Ther , vol.23 , Issue.8 , pp. 1143-1151
    • Capanni, M.1    Calella, F.2    Biagini, M.R.3    Genise, S.4    Raimondi, L.5    Bedogni, G.6
  • 88
    • 11144257762 scopus 로고    scopus 로고
    • Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States
    • Ruhl C.E., and Everhart J.E. Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States. Gastroenterology 128 1 (2005) 24-32
    • (2005) Gastroenterology , vol.128 , Issue.1 , pp. 24-32
    • Ruhl, C.E.1    Everhart, J.E.2
  • 89
    • 0034126755 scopus 로고    scopus 로고
    • Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study
    • Lavine J.E. Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr 136 (2000) 734-738
    • (2000) J Pediatr , vol.136 , pp. 734-738
    • Lavine, J.E.1
  • 91
    • 0034799895 scopus 로고    scopus 로고
    • Plasma transforming growth factor β1 level and efficacy of α-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study
    • Hasegawa T., Yoneda M., Nakamura K., Makino I., and Terano A. Plasma transforming growth factor β1 level and efficacy of α-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther 15 (2001) 1667-1672
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1667-1672
    • Hasegawa, T.1    Yoneda, M.2    Nakamura, K.3    Makino, I.4    Terano, A.5
  • 92
    • 14944359845 scopus 로고    scopus 로고
    • A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis
    • Sanyal A.J., Mofrad P.S., Contos M.J., Sargeant C., Luketic V.A., Sterling R.K., et al. A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol 2 (2004) 1107-1115
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 1107-1115
    • Sanyal, A.J.1    Mofrad, P.S.2    Contos, M.J.3    Sargeant, C.4    Luketic, V.A.5    Sterling, R.K.6
  • 94
    • 0036024264 scopus 로고    scopus 로고
    • S-adenosylmethionine, cytokines and alcoholic liver disease
    • McClain C.J., Hill D.B., Song Z., Chawla R., Watson W., Chen T., et al. S-adenosylmethionine, cytokines and alcoholic liver disease. Alcohol 27 3 (2002) 185-192
    • (2002) Alcohol , vol.27 , Issue.3 , pp. 185-192
    • McClain, C.J.1    Hill, D.B.2    Song, Z.3    Chawla, R.4    Watson, W.5    Chen, T.6
  • 95
    • 0141957302 scopus 로고    scopus 로고
    • S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice small star, filled
    • Song Z., Zhou Z., Chen T., Hill D., Kang J., Barve S., et al. S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice small star, filled. J Nutr Biochem 14 10 (2003) 591-597
    • (2003) J Nutr Biochem , vol.14 , Issue.10 , pp. 591-597
    • Song, Z.1    Zhou, Z.2    Chen, T.3    Hill, D.4    Kang, J.5    Barve, S.6
  • 96
    • 0038586297 scopus 로고    scopus 로고
    • S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes
    • Song Z., Barve S., Chen T., Nelson W., Uriarte S., Hill D., et al. S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes. Am J Physiol Gastrointest Liver Physiol 284 6 (2003) G949-G955
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , Issue.6
    • Song, Z.1    Barve, S.2    Chen, T.3    Nelson, W.4    Uriarte, S.5    Hill, D.6
  • 97
    • 0344867846 scopus 로고    scopus 로고
    • S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial
    • Mato J.M., Camara J., Fernandez de Paz J., Caballeria L., Coll S., Caballero A., et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol 30 6 (1999) 1081-1089
    • (1999) J Hepatol , vol.30 , Issue.6 , pp. 1081-1089
    • Mato, J.M.1    Camara, J.2    Fernandez de Paz, J.3    Caballeria, L.4    Coll, S.5    Caballero, A.6
  • 98
    • 4544358286 scopus 로고    scopus 로고
    • Betaine in human nutrition
    • Craig S.A. Betaine in human nutrition. Am J Clin Nutr 80 3 (2004) 539-549
    • (2004) Am J Clin Nutr , vol.80 , Issue.3 , pp. 539-549
    • Craig, S.A.1
  • 99
    • 0042920699 scopus 로고    scopus 로고
    • Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats
    • Barak A.J., Beckenhauer H.C., Mailliard M.E., Kharbanda K.K., and Tuma D.J. Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats. J Nutr 133 9 (2003) 2845-2848
    • (2003) J Nutr , vol.133 , Issue.9 , pp. 2845-2848
    • Barak, A.J.1    Beckenhauer, H.C.2    Mailliard, M.E.3    Kharbanda, K.K.4    Tuma, D.J.5
  • 100
    • 0034834208 scopus 로고    scopus 로고
    • Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
    • Abdelmalek M.F., Angulo P., Jorgensen R.A., Sylvestre P.B., and Lindor K.D. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 96 9 (2001) 2534-2536
    • (2001) Am J Gastroenterol , vol.96 , Issue.9 , pp. 2534-2536
    • Abdelmalek, M.F.1    Angulo, P.2    Jorgensen, R.A.3    Sylvestre, P.B.4    Lindor, K.D.5
  • 103
    • 24044547078 scopus 로고    scopus 로고
    • Zinc prevention and treatment of alcoholic liver disease
    • Kang Y.J., and Zhou Z. Zinc prevention and treatment of alcoholic liver disease. Mol Aspects Med 26 (2005) 391-404
    • (2005) Mol Aspects Med , vol.26 , pp. 391-404
    • Kang, Y.J.1    Zhou, Z.2
  • 105
    • 0041422646 scopus 로고    scopus 로고
    • A critical involvement of oxidative stress in acute alcohol-induced hepatic TNF-alpha production
    • Zhou Z., Wang L., Song Z., Lambert J.C., McClain C.J., and Kang Y.J. A critical involvement of oxidative stress in acute alcohol-induced hepatic TNF-alpha production. Am J Pathol 163 (2003) 1137-1146
    • (2003) Am J Pathol , vol.163 , pp. 1137-1146
    • Zhou, Z.1    Wang, L.2    Song, Z.3    Lambert, J.C.4    McClain, C.J.5    Kang, Y.J.6
  • 106
    • 0038814267 scopus 로고    scopus 로고
    • Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice
    • Lambert J.C., Zhou Z., Wang L., Song Z., McClain C.J., and Kang Y.J. Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice. J Pharmacol Exp Ther 305 (2003) 880-886
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 880-886
    • Lambert, J.C.1    Zhou, Z.2    Wang, L.3    Song, Z.4    McClain, C.J.5    Kang, Y.J.6


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