Fatty liver - An additional and treatable feature of the insulin resistance syndrome

QJM: An International Journal of Medicine

Volumn 92, Issue 2, 1999, Pages 73-79

  Knobler, H ^a   Schattner, A ^a   Zhornicki, T ^a   Malnick, S D H ^a   Keter, D ^a   Sokolovskaya, N ^a,b   Lurie, Y ^a   Bass, D D ^a  

^a KAPLAN MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIVER ENZYME; TRIACYLGLYCEROL;

ADULT; AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY FAT; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; DIABETES MELLITUS; DIET THERAPY; ECHOGRAPHY; ENZYME BLOOD LEVEL; FATTY LIVER; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; HYPERTRIGLYCERIDEMIA; HYPOTHESIS; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPID BLOOD LEVEL; LIVER BIOPSY; MALE; OBESITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

EID: 0033055916     PISSN: 00335622     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Ludwig J, Viggiano TR, McGill DB, Ott BJ. Nonalcoholic steatohepatitis: Mayo Clinic Experience with a hitherto unnamed disease. Mayo Clin Proc 1980; 55:434-8.
2. Sheth SG, Gordon FD, Chopra S. Nonalcoholic steatohepatitis. Ann Intern Med 1997; 126:137-45.
3. Ludwig J, McGill DB, Lindor KD. Review: nonalcoholic steatohepatitis. Gastroenterol Hepatol 1997; 12:398-403.
4. Saverymuttu SH, Joseph AEA, Maxwell JD. Ultrasound scanning in the detection of hepatic fibrosis and steatosis. Br Med J 1986; 292:13-15.
5. Powell EE, Cooksley WGE, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: Follow-up study of forty-two patients for up to 21 years. Hepatology 1990; 11:74-80.
6. Itoh S, Youngel T, Kawagoe K. Comparison between nonalcoholic teatohepatitis and alcoholic hepatitis. Am J Gastroenterol 1987; 82:650-4.
7. Lee RG. Nonalcoholic steatohepatitis: A study of 49 patients. Hum Pathol 1989; 20:594-8.
8. Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: Autopsy study with analysis of risk factors. Hepatology 1990; 12:1106-10.
9. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri BA. Nonalcoholic steatohepatitis: An expanded clinical entity. Gastroenterology 1994; 107:1103-9.
10. Teli MR, James OFW, Burt AD, Bennet MK, Day CP. The natural history of nonalcoholic fatty liver: A follow-up study. Hepatology 1995; 22:1714-9.
11. Abdelmalek M, Ludwig J, Lindor KD. Two cases from the spectrum of nonalcoholic steatohepatitis. J Clin Gastroenterol. 1995; 20:127-30.
12. Okolo III P, Diehl AM. Nonalcoholic steatohepatitis and focal fatty liver. In: Feldman M, Scharschmidt BF, Sleisenger MH, eds. Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. Philadelphia, WB Saunders, 1998:1215-20.
13. Quinn SF, Gosink BB. Characteristic sonographic signs of hepatic fatty infiltration. Am J Roentgenol 1985; 145:753-5.
14. Lean MEJ, Han TS, Morrison CE. Waist circumference as a measure for indicating need for weight management. Br Med J 1995; 311:158-61.
15. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20:1183-97.
16. Meigs JB, D'Agostino RB, Wilson PWF, Cupples LA, Nathan DM, Singer DE. Risk variable clustering in the insulin resistance syndrome: the Framingham Offspring Study. Diabetes 1997; 46:1594-600.
17. Heiss G, Tamir I, Davis CE, Tyroler HA, Rifkind BM, Schonfeld G, et al. Lipoprotein-cholesterol distributions in selected North American populations: The Lipid Research Clinics Program Prevalence Study. Circulation 1980; 61:302-15.
18. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19:1513-20.
19. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection Evaluation, and Treatment of High Blood Cholesterol in Adults. JAMA 1993; 269:3015-23.
20. Daly PA, Solomon CG, Manson JE. Risk modification in the obese patient. In: Manson JE, Ridker PM, Gaziano MJ, Hennekens Ch, eds. Prevention of myocardial infarction. New York, Oxford University Press, 1996.
21. Hultcrantz R, Gabrielsson N. Patients with persistent elevation of aminotransferases: investigation with ultrasonography, radionuclide imaging and liver biopsy. J Intern Med 1993; 223:7-12.
22. Reaver GM. Role of insulin resistance in human disease. Diabetes 1988; 37:1595-607.
23. DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991; 14:173-94.
24. Pounder D, Carson D, Davison M, Orihara Y. Evaluation of indices of obesity in men: descriptive study. Br Med J 1998; 316:1428-9.
25. Macor C, Ruggeri A, Mazzonetto P, Federspil G, Cobelli C, Vettor R. Visceral adipose tissue impairs insulin secretion and insulin sensitivity but not energy expenditure in obesity. Metabolism 1997; 46:123-9.
26. Matsuzawa Y, Shiml, Nakamura T, Keno Y, Tokunaga K. Pathophysiology and pathogenesis of visceral fat obesity. Diabetes Res Clin Pract 1994; 24:S111-16.
27. Akpunonu BE, Federman DJ. Nonalcoholic steatohepatit. Ann Intern Med 1997; 127:410.
28. Howard BV. Lipoprotein metabolism in diabetes mellitus. J Lipid Res 1987; 28:613-28.
29. Walker M, Berrish TS, Stewart MW, Humphriss DB, Barriocanal L, Alberti KG. Metabolic heterogeneity in impaired glucose tolerance. Metabolism 1997; 46:914-7.
30. Lewis GF, Steiner G. Acute effects of insulin in the control of VLDL production in humans: Implications for the insulin-resistant states. Diabetes Care 1996; 19:390-3.
31. Caprio S, Boulware S, Diamond M, Sherwin RS, Carpenter TO, Rubin K, et al. Insulin resistance: an early metabolic effect of Turner's syndrome. J Clin Endocrinol Metab 1991; 72:832-6.
32. Oehler G, Bleyl H, Matthes KJ. Hyperinsulinemia in hepatic steatosis. Int J Obes 1982; 6(Suppl 1):137-44.
33. Kawasaki T, Hashimoto N, Kikuchi T, Takahashi H, Uchiyama M. The relationship between fatty liver and hyperinsulinemia in obese Japanese children. J Ped Gastroenterol 1997; 24:317-21.
34. Day CP, James OFW. Steatohepatitis: A tale of two 'hits'? Gastroenterology 1998; 114:842-5.
35. Palmer M, Schaffner F. Effect of weight reduction on hepatic abnormalities in overweight patients. G 19??; 99:1408-13.
36. Drenick EJ, Simmons F, Murphy JF. Effect on hepatic morphology of treatment of obesity fasting, reducing diets and small-bowel bypass. N Engl J Med 1970; 282:829-34.