-
2
-
-
0031911356
-
SMADs: Mediators and regulators of TGF-β responses
-
Kretzschmar M, Massague J. SMADs: mediators and regulators of TGF-β responses. Curr Opin Genet Dev 1998;8:103-11.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 103-111
-
-
Kretzschmar, M.1
Massague, J.2
-
3
-
-
0037204990
-
Signal transduction by the TGF-beta superfamily
-
Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002;296:1646-7.
-
(2002)
Science
, vol.296
, pp. 1646-1647
-
-
Attisano, L.1
Wrana, J.L.2
-
6
-
-
0027136742
-
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-β1
-
Pierce DJ, Johnson MD, Matsui V, Robinson SD, Gold LJ, Purchio AF, et al. Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-β1. Genes Dev 1993;7:2308-17.
-
(1993)
Genes Dev
, vol.7
, pp. 2308-2317
-
-
Pierce, D.J.1
Johnson, M.D.2
Matsui, V.3
Robinson, S.D.4
Gold, L.J.5
Purchio, A.F.6
-
7
-
-
2642614530
-
Transforming growth factor-b1 is a new form of tumor suppressor with true haploid insufficiency
-
Tang B, Bottinger EP, Jakowlew SB, Bagnall KM, Mariano J, Anver MR, et al. Transforming growth factor-b1 is a new form of tumor suppressor with true haploid insufficiency. Nat Med 1998;4:802-7.
-
(1998)
Nat Med
, vol.4
, pp. 802-807
-
-
Tang, B.1
Bottinger, E.P.2
Jakowlew, S.B.3
Bagnall, K.M.4
Mariano, J.5
Anver, M.R.6
-
8
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor B receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
-
Böttinger EP, Jakubczak JL, Haines DC, Bagnall K, Wakefield LM. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor B receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res 1997;57:5564-70.
-
(1997)
Cancer Res
, vol.57
, pp. 5564-5570
-
-
Böttinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
9
-
-
0030793645
-
Transforming growth factor-β in breast cancer: A working hypothesis
-
Reiss M, Barcellos-Hoff MH. Transforming growth factor-β in breast cancer: a working hypothesis. Breast Cancer Res Treat 1997;45:81-95.
-
(1997)
Breast Cancer Res Treat
, vol.45
, pp. 81-95
-
-
Reiss, M.1
Barcellos-Hoff, M.H.2
-
10
-
-
0026520147
-
Transforming growth factor beta 1 in ductal carcinoma in situ and invasive carcinomas of the breast
-
Walker RA, Dearing S. Transforming growth factor beta 1 in ductal carcinoma in situ and invasive carcinomas of the breast. Eur J Cancer 1992;28:641-4.
-
(1992)
Eur J Cancer
, vol.28
, pp. 641-644
-
-
Walker, R.A.1
Dearing, S.2
-
11
-
-
0027053058
-
Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer
-
Gorsch SM, Memoli VA, Stukel TA, Gold LI, Arrick BA. Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer. Cancer Res 1992; 52:6949-52.
-
(1992)
Cancer Res
, vol.52
, pp. 6949-6952
-
-
Gorsch, S.M.1
Memoli, V.A.2
Stukel, T.A.3
Gold, L.I.4
Arrick, B.A.5
-
12
-
-
0029662049
-
TGF-β1 and Ha-Ras collaborate on modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Deli J, Rudar C, Schwartz H, Beug H, Reichman E. TGF-β1 and Ha-Ras collaborate on modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 1996;10:2462-77.
-
(1996)
Genes Dev
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Deli, J.2
Rudar, C.3
Schwartz, H.4
Beug, H.5
Reichman, E.6
-
13
-
-
11944255353
-
Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential
-
Weich DR, Fabra A, Nakaijama M. Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc Natl Acad Sci USA 1990;87:7678-82.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7678-7682
-
-
Weich, D.R.1
Fabra, A.2
Nakaijama, M.3
-
14
-
-
0032918414
-
TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin JJ, Selander K, Chirgwin JM, Dallas M, Grubbs BG, Wieser R, et al. TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 1999;103:197-206.
-
(1999)
J Clin Invest
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
-
15
-
-
0032547895
-
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
-
Oft M, Heider KH, Beug H. TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis. Cell Biol 1998;8:1243-52.
-
(1998)
Cell Biol
, vol.8
, pp. 1243-1252
-
-
Oft, M.1
Heider, K.H.2
Beug, H.3
-
16
-
-
0034004714
-
Loss of expression of transforming growth factor beta type II receptor correlates with high tumor grade in human breast in situ and invasive carcinomas
-
Gobbi H, Arteaga Cl, Jensen RA, Simpson JF, Dupont WD, Olson ST, et al. Loss of expression of transforming growth factor beta type II receptor correlates with high tumor grade in human breast in situ and invasive carcinomas. Histopathology 2000;36:168-77.
-
(2000)
Histopathology
, vol.36
, pp. 168-177
-
-
Gobbi, H.1
Arteaga, C.2
Jensen, R.A.3
Simpson, J.F.4
Dupont, W.D.5
Olson, S.T.6
-
18
-
-
0034468039
-
Transforming growth factor-β and breast cancer: Tumor promoting effects of transforming growth factor-β
-
Dumont N, Arteaga CL. Transforming growth factor-β and breast cancer: tumor promoting effects of transforming growth factor-β. Breast Cancer Res 2000;2:125-32.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 125-132
-
-
Dumont, N.1
Arteaga, C.L.2
-
19
-
-
0025952663
-
Transforming growth factor-beta 1 upregulates types IV collagenase expression in cultured human keratinocytes
-
Salo T, Lyons JG, Rahemtulla F, Birkedal-Hansen H, Larjava H. Transforming growth factor-beta 1 upregulates types IV collagenase expression in cultured human keratinocytes. J Biol Chem 1991;266:11436-41.
-
(1991)
J Biol Chem
, vol.266
, pp. 11436-11441
-
-
Salo, T.1
Lyons, J.G.2
Rahemtulla, F.3
Birkedal-Hansen, H.4
Larjava, H.5
-
20
-
-
0025866180
-
Transcriptional and post-transcriptional regulation of 72 kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression
-
Overall CM, Wrana JL, Sodek J. Transcriptional and post-transcriptional regulation of 72 kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem 1991;266:14064-71.
-
(1991)
J Biol Chem
, vol.266
, pp. 14064-14071
-
-
Overall, C.M.1
Wrana, J.L.2
Sodek, J.3
-
21
-
-
0039552125
-
Transforming growth factor-β induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen activated protein kinase
-
Ravanti L, Hakkinen L, Larjava H, Saarialho-Kere U, Foschi M, Han J, et al. Transforming growth factor-β induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen activated protein kinase. J Biol Chem 1999;274:37292-300.
-
(1999)
J Biol Chem
, vol.274
, pp. 37292-37300
-
-
Ravanti, L.1
Hakkinen, L.2
Larjava, H.3
Saarialho-Kere, U.4
Foschi, M.5
Han, J.6
-
22
-
-
2242476591
-
Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix Metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways
-
Leivonen SK, Chantry A, Hakkinen L, Han J, Kahari VM. Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix Metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways. J Biol Chem 2002;277:46338-46.
-
(2002)
J Biol Chem
, vol.277
, pp. 46338-46346
-
-
Leivonen, S.K.1
Chantry, A.2
Hakkinen, L.3
Han, J.4
Kahari, V.M.5
-
23
-
-
0035914339
-
Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
-
Yuan W, Varga J. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J Biol Chem 2001;276:38502-10.
-
(2001)
J Biol Chem
, vol.276
, pp. 38502-38510
-
-
Yuan, W.1
Varga, J.2
-
24
-
-
0038532305
-
The comparative role of activator protein-1 and smad factors in the regulation of TIMP-1 and MMP-1 gene expression by transforming growth factor-β1
-
Hall MC, Young DA, Waters JG, Rowan AD, Chantry A, Edwards DR, et al. The comparative role of activator protein-1 and smad factors in the regulation of TIMP-1 and MMP-1 gene expression by transforming growth factor-β1. J Biol Chem 2003;278:10304-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 10304-10313
-
-
Hall, M.C.1
Young, D.A.2
Waters, J.G.3
Rowan, A.D.4
Chantry, A.5
Edwards, D.R.6
-
25
-
-
0642306119
-
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line
-
Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, et al. Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res 2003;5:R187-98.
-
(2003)
Breast Cancer Res
, vol.5
-
-
Xie, L.1
Law, B.K.2
Aakre, M.E.3
Edgerton, M.4
Shyr, Y.5
Bhowmick, N.A.6
-
26
-
-
0033373288
-
Reduced cadherin/ catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation
-
Perry I, Tselepis C, Hoyland J, Iqbal TH, Scott D, Sanders SA, et al. Reduced cadherin/ catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation. Lab Invest 1999;79:1489-99.
-
(1999)
Lab Invest
, vol.79
, pp. 1489-1499
-
-
Perry, I.1
Tselepis, C.2
Hoyland, J.3
Iqbal, T.H.4
Scott, D.5
Sanders, S.A.6
-
27
-
-
0032882539
-
Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype
-
Janji B, Melchior C, Gouon V, Vallar L, Kieffer N. Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype. Int J Cancer 1999;83:255-62.
-
(1999)
Int J Cancer
, vol.83
, pp. 255-262
-
-
Janji, B.1
Melchior, C.2
Gouon, V.3
Vallar, L.4
Kieffer, N.5
-
28
-
-
17644415807
-
Pathology and Genetics. Tumors of the Breast and Female Genital Organs
-
Tavassoéli FA, Devilee P. Pathology and Genetics. Tumors of the Breast and Female Genital Organs. IARC WHO Classification of Tumors, No. 4, 2003.
-
(2003)
IARC WHO Classification of Tumors
, Issue.4
-
-
Tavassoéli, F.A.1
Devilee, P.2
-
29
-
-
0029145870
-
Histological grading of breast carcinomas: A study of interobserved agreement
-
Robins P, Pinder S, de Klerk N. Histological grading of breast carcinomas: a study of interobserved agreement. Hum Pathol 1995;28:873-9.
-
(1995)
Hum Pathol
, vol.28
, pp. 873-879
-
-
Robins, P.1
Pinder, S.2
de Klerk, N.3
-
30
-
-
0026033066
-
Staging and follow-up of breast cancer patients
-
Kinne DW. Staging and follow-up of breast cancer patients. Cancer 1991;67:1196-8.
-
(1991)
Cancer
, vol.67
, pp. 1196-1198
-
-
Kinne, D.W.1
-
31
-
-
0034486459
-
DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer
-
Nakopoulou L, Lazaris AC, Kavantzas N, Alexandrou P, Athanassiadou P, Keramopoulos A, et al. DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer. Pathobiology 2000;68:137-43.
-
(2000)
Pathobiology
, vol.68
, pp. 137-143
-
-
Nakopoulou, L.1
Lazaris, A.C.2
Kavantzas, N.3
Alexandrou, P.4
Athanassiadou, P.5
Keramopoulos, A.6
-
32
-
-
0036144623
-
Correlation of tissue inhibitor of metalloproteinase-2 with proliferative activity and patients' survival in breast cancer
-
Nakopoulou S, Katsarou S, Giannopoulou I, Alexandrou P, Tsirmpa I, Panayotopoulou E, et al. Correlation of tissue inhibitor of metalloproteinase-2 with proliferative activity and patients' survival in breast cancer. Mod Pathol 2002;15:26-34.
-
(2002)
Mod Pathol
, vol.15
, pp. 26-34
-
-
Nakopoulou, S.1
Katsarou, S.2
Giannopoulou, I.3
Alexandrou, P.4
Tsirmpa, I.5
Panayotopoulou, E.6
-
33
-
-
0036278085
-
Abnormal a-catenin expression in invasive breast cancer correlates with poor patient survival
-
Nakopoulou L, Gakiopoulou-Givalou H, Karayiannakis AJ, Giannopoulou I, Keramopoulos A, Davaris P, et al. Abnormal a-catenin expression in invasive breast cancer correlates with poor patient survival. Histopathology 2002;40:536-46.
-
(2002)
Histopathology
, vol.40
, pp. 536-546
-
-
Nakopoulou, L.1
Gakiopoulou-Givalou, H.2
Karayiannakis, A.J.3
Giannopoulou, I.4
Keramopoulos, A.5
Davaris, P.6
-
34
-
-
28844443277
-
Effects of different ERK2 protein localizations on prognosis of patients with invasive breast carcinoma
-
Nakopoulou L, Mylona E, Rafailidis P, Alexandrou P, Giannopoulou I, Keramopoulos A. Effects of different ERK2 protein localizations on prognosis of patients with invasive breast carcinoma. APMIS 2005;113:693-701.
-
(2005)
APMIS
, vol.113
, pp. 693-701
-
-
Nakopoulou, L.1
Mylona, E.2
Rafailidis, P.3
Alexandrou, P.4
Giannopoulou, I.5
Keramopoulos, A.6
-
35
-
-
0025878274
-
A multicentre study into the reliability of steroid receptor immunocytochemical assay quantification
-
McClelland RA, Wilson D, Leake R, Finlay P, Nicholson RI. A multicentre study into the reliability of steroid receptor immunocytochemical assay quantification. Eur J Cancer 1991;27:711-6.
-
(1991)
Eur J Cancer
, vol.27
, pp. 711-716
-
-
McClelland, R.A.1
Wilson, D.2
Leake, R.3
Finlay, P.4
Nicholson, R.I.5
-
36
-
-
12244293337
-
The tumor microenvironment: A potential arbitrator of the tumor suppressive and promoting actions of TGFβ
-
Dumont N, Artega CL. The tumor microenvironment: a potential arbitrator of the tumor suppressive and promoting actions of TGFβ. Differentiation 2002;70:574-82.
-
(2002)
Differentiation
, vol.70
, pp. 574-582
-
-
Dumont, N.1
Artega, C.L.2
-
37
-
-
0037081179
-
Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: A tissue microarray study
-
Xie W, Martens JC, Reiss DJ, Rimm DL, Camp RL, Haffty BG, et al. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. Cancer Res 2002;62:497-505.
-
(2002)
Cancer Res
, vol.62
, pp. 497-505
-
-
Xie, W.1
Martens, J.C.2
Reiss, D.J.3
Rimm, D.L.4
Camp, R.L.5
Haffty, B.G.6
-
38
-
-
0024420188
-
Effects of transforming growth factor β on growth of human mammary epithelial cells in culture
-
Hosobuchi M, Stampfer MR. Effects of transforming growth factor β on growth of human mammary epithelial cells in culture. In Vitro Cell Dev Biol 1989;25:705-13.
-
(1989)
In Vitro Cell Dev Biol
, vol.25
, pp. 705-713
-
-
Hosobuchi, M.1
Stampfer, M.R.2
-
39
-
-
0024366047
-
TGF-b1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization
-
Daniel CW, Silberstein GB, Van Horn K, Strickland P, Robinson S. TGF-b1-induced inhibition of mouse mammary ductal growth: developmental specificity and characterization. Dev Biol 1989;135:20-30.
-
(1989)
Dev Biol
, vol.135
, pp. 20-30
-
-
Daniel, C.W.1
Silberstein, G.B.2
Van Horn, K.3
Strickland, P.4
Robinson, S.5
-
40
-
-
0032828502
-
Transforming growth factor-β responsiveness in DPC4/SMAD4-null cancer cells
-
Dai JL, Schutte M, Bansal RK, Wilentz RE, Sugar AY, Kern SE. Transforming growth factor-β responsiveness in DPC4/SMAD4-null cancer cells. Mol Carcinog 1999;26:37-43.
-
(1999)
Mol Carcinog
, vol.26
, pp. 37-43
-
-
Dai, J.L.1
Schutte, M.2
Bansal, R.K.3
Wilentz, R.E.4
Sugar, A.Y.5
Kern, S.E.6
-
41
-
-
0034710157
-
The evolution of cell adhesion
-
Hynes RO, Zhao Q. The evolution of cell adhesion. J Cell Biol 2000;150:F89-F95.
-
(2000)
J Cell Biol
, vol.150
-
-
Hynes, R.O.1
Zhao, Q.2
-
42
-
-
0036992767
-
Altered expression of the catenin p 120 in human cancer: Implications for tumor progression
-
Thoreson MA, Reynolds AB. Altered expression of the catenin p 120 in human cancer: implications for tumor progression. Differentiation 2002;70:583-9.
-
(2002)
Differentiation
, vol.70
, pp. 583-589
-
-
Thoreson, M.A.1
Reynolds, A.B.2
-
43
-
-
12344252369
-
Differential gene expression of TGFβ inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue
-
Reinholz MM, An MW, Johnsen SA, Subramaniam M, Suman VJ, Ingle JN, et al. Differential gene expression of TGFβ inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue. Breast Cancer Res Treat 2004;166:1-14.
-
(2004)
Breast Cancer Res Treat
, vol.166
, pp. 1-14
-
-
Reinholz, M.M.1
An, M.W.2
Johnsen, S.A.3
Subramaniam, M.4
Suman, V.J.5
Ingle, J.N.6
-
44
-
-
0036995757
-
Matrix metalloproteinases in tumor-host cell communication
-
Lynch CC, Matrisian LM. Matrix metalloproteinases in tumor-host cell communication. Differentiation 2002;70:561-73.
-
(2002)
Differentiation
, vol.70
, pp. 561-573
-
-
Lynch, C.C.1
Matrisian, L.M.2
-
46
-
-
0037426578
-
Membrane-type 1 matrix metalloproteinase: A key enzyme for tumor invasion
-
Seiki M. Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. Cancer Lett 2003;194:1-11.
-
(2003)
Cancer Lett
, vol.194
, pp. 1-11
-
-
Seiki, M.1
-
47
-
-
0037358503
-
Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis
-
Sounni NE, Janssen M, Foidart JM, Noel A. Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis. Matrix Biol 2003;22:55-61.
-
(2003)
Matrix Biol
, vol.22
, pp. 55-61
-
-
Sounni, N.E.1
Janssen, M.2
Foidart, J.M.3
Noel, A.4
-
48
-
-
0037192933
-
The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
-
Mu D, Cambier S, Fjellbirkeland L, Baron JL, Munger JS, Kawakatsu H, et al. The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1. J Cell Biol 2002;157:493-507.
-
(2002)
J Cell Biol
, vol.157
, pp. 493-507
-
-
Mu, D.1
Cambier, S.2
Fjellbirkeland, L.3
Baron, J.L.4
Munger, J.S.5
Kawakatsu, H.6
-
49
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson G, Robinson F, Gibson TB, Xu BE, Karandikar M, Berman K, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 2001;22:153-83.
-
(2001)
Endocr Rev
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.B.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
-
50
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker MP, Parks WT, Frank CJ, Castagnino P, Bottaro DP, Roberts AB, et al. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 1998;12:1587-92.
-
(1998)
Genes Dev
, vol.12
, pp. 1587-1592
-
-
de Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
|