Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells

Biophysical Journal

Volumn 92, Issue 3, 2007, Pages 816-830

  Krishnan, J ^a   Iglesias, P A ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELLULAR DISTRIBUTION; CHEMOTAXIS; DICTYOSTELIUM; EUKARYOTE; MATHEMATICAL ANALYSIS; POLARIZATION;

EUKARYOTA;

EID: 33846815127     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.087353     Document Type: Article

References (53)

1. Haugh, J. M., F. Codazzi, M. Teruel, and T. Meyer. 2000. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151:1269-1280.
2. Servant, G., O. D. Weiner, P. Herzmark, T. Balla, J. W. Sedat, and H. R. Bourne. 2000. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science. 287:1037-1040.
3. Parent, C. A., and P. N. Devreotes. 1999. A cell's sense of direction. Science. 284:765-770.
4. Iglesias, P. A., and A. Levchenko. 2002. Modeling the cell's guidance system. Sci. STKE. 2002:RE12.
5. Devreotes, P., and C. Janetopoulos. 2003. Eukaryotic chemotaxis: distinctions between directional sensing and polarization. J. Biol. Chem. 278:20445-20448.
6. Rappel, W.-J., P. J. Thomas, W. F. Loomis, and H. Levine. 2002. Establishing direction during chemotaxis in eukaryotic cells. Biophys. J. 83:1361-1367.
7. Skupsky, R., W. Losert, and R. J. Nossal. 2005. Distinguishing modes of eukaryotic gradient sensing nematode sperm cells. Biophys. J. 89:2806-2824.
8. Postma, M., and P. J. Van Haastert. 2001. A diffusion-translocation model for gradient sensing by chemotactic cells. Biophys. J. 81:1314-1323.
9. Narang, A., K. K. Subramanian, and D. A. Lauffenburger. 2001. A mathematical model for chemoattractant gradient sensing based on receptor-regulated membrane phospholipid signaling dynamics. Ann. Biomed. Eng. 29:677-691.
10. Subramanian, K. K., and A. Narang. 2004. A mechanistic model for eukaryotic gradient sensing: spontaneous and induced phosphoinositide polarization. J. Theor. Biol. 231:49-67.
11. Parent, C. A., B. J. Blacklock, W. M. Froehlich, D. B. Murphy, and P. N. Devreotes. 1998. G protein signaling events are activated at the leading edge of chemotactic cells. Cell. 95:81-91.
12. Janetopoulos, C., L. Ma, P. N. Devreotes, and P. A. Iglesias. 2004. Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton. Proc. Natl. Acad. Sci. USA. 101:8951-8956.
13. Krishnan, J., and P. A. Iglesias. 2004. A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells. J. Theor. Biol. 229:85-99.
14. 3 response in Dictyostelium cells. Biophys. J. 87:3764-3774.
15. Arrieumerlou, C., and T. Meyer. 2005. A local coupling model and compass parameter for eukaryotic chemotaxis. Dev. Cell. 8:215-227.
16. Lauffenburger, D. A., and A. F. Horwitz. 1996. Cell migration: a physically integrated molecular process. Cell. 84:359-369.
17. Drubin, D. G., editor. 2000. Cell Polarity. Oxford Press, London.
18. Nelson, W. J. 2003. Adaptation of core mechanisms to generate cell polarity. Nature. 422:766-774.
19. Wedlich-Soldner, R., and R. Li. 2003. Spontaneous cell polarization: undermining determinism. Nat. Cell Biol. 5:267-270.
20. Sohrmann, M., and M. Peter. 2003. Polarizing without a c(l)ue. Trends Cell Biol. 13:526-533.
21. Kimmel, A. R., and R. A. Firtel. 2004. Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response. Curr. Opin. Genet. Dev. 14:540-549.
22. Van Haastert, P. J. M., and P. N. Devreotes. 2004. Chemotaxis: signaling the way forward. Nat. Rev. Mol. Cell Biol. 5:626-634.
23. Manahan, C. L., P. A. Iglesias, Y. Long, and P. N. Devreotes. 2004. Chemoattractant signaling in Dictyostelium. Annu. Rev. Cell Dev. Biol. 20:223-253.
24. Servant, G., O. D. Weiner, E. R. Neptune, J. W. Sedat, and H. R. Bourne. 1999. Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. Mol. Biol. Cell. 10:1163-1178.
25. Jin, T., N. Zhang, Y. Long, C. A. Parent, and P. N. Devreotes. 2000. Localization of the G protein bg complex in living cells during chemotaxis. Science. 287:1034-1036.
26. Chung, C. Y., S. Funamoto, and R. A. Firtel. 2001. Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem. Sci. 26:557-566.
27. Iijima, M., and P. Devreotes. 2002. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell. 109:599-610.
28. Funamoto, S., R. Meili, S. Lee, L. Parry, and R. A. Firtel. 2002. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109:611-623.
29. Krishnan, J., and P. A. Iglesias. 2005. A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells. II: Input-output analysis. J. Theor. Biol. 235:504-520.
30. Levchenko, A., and P. A. Iglesias. 2002. Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils. Biophys. J. 82:50-63.
31. Wolpert, L. 2002. Principles of Development. Oxford Press, London.
32. Narang, A. 2006. Spontaneous polarization in eukaryotic gradient sensing: a mathematical model based on mutual inhibition of frontness and backness pathways. J. Theor. Biol. 240:538-553.
33. Gamba, A., A. de Candia, S. Di Talia, A. Coniglio, F. Bussolino, and G. Serini. 2005. Diffusion-limited phase separation in eukaryotic chemotaxis. Proc. Natl. Acad. Sci. USA. 102:16927-16932.
34. Levine, H., and W.-J. Rappel. 2005. Membrane-bound Turing patterns. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 72:061912.
35. Maree, A., A. Jilkine, A. Dawes, V. Grieneisen, and L. Edelstein-Keshet. 2006. Polarization and movement of keratocytes: a multiscale modeling approach. Bull. Math. Biol. 68:1169-1211.
36. 3 accumulation and have unique roles during chemotaxis. Mol. Biol. Cell. 14:5028-5037.
37. Albrecht, E., and H. R. Petty. 1998. Cellular memory: neutrophil orientation reverses during temporally decreasing chemoattractant concentrations. Proc. Natl. Acad. Sci. USA. 95:5039-5044.
38. Devreotes, P. N., and S. H. Zigmond. 1988. Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium. Annu. Rev. Cell Biol. 4:649-686.
39. Krishnan, J., and P. A. Iglesias. 2003. Analysis of the signal transduction properties of a module of spatial sensing in eukaryotic chemotaxis. Bull. Math. Biol. 65:95-128.
40. Wang, F., P. Herzmark, O. D. Weiner, S. Srinivasan, G. Servant, and H. R. Bourne. 2002. Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4:513-518.
41. Pirone, D. M., and C. S. Chen. 2004. Strategies for engineering the adhesive microenvironment. J. Mammary Gland Biol. Neoplasia. 9:405-417.
42. Xu, J., F. Wang, A. Van Keymeulen, P. Herzmark, A. Straight, K. Kelly, Y. Takuwa, N. Sugimoto, T. Mitchison, and H. R. Bourne. 2003. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell. 114:201-214.
43. Postma, M., L. Bosgraaf, H. M. Loovers, and P. J. Van Haastert. 2004. Chemotaxis: signaling modules join hands at front and tail. EMBO Rep. 5:35-40.
44. Ridley, A., M. Schwartz, K. Burridge, R. Firtel, M. Ginsberg, G. Borisy, J. Parsons, and A. Horwitz. 2003. Cell migration: integrating signals from front to back. Science. 302:1704-1709.
45. Williams, H. P., and A. J. Harwood. 2003. Cell polarity and Dictyostelium development. Curr. Opin. Microbiol. 6:621-627.
46. Gracheva, M. E., and H. G. Othmer. 2004. A continuum model of motility in amoeboid cells. Bull. Math. Biol. 66:167-193.
47. Mogilner, A., and D. Verzi. 2003. A simple 1-D physical model for the crawling of nematode sperm cells. J. Stat. Phys. 110:1169-1189.
48. Li Jeon, N., H. Baskaran, S. K. W. Dertinger, G. M. Whitesides, L. Van de Water, and M. Toner. 2002. Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat. Biotechnol. 20:826-830.
49. Song, L., S. M. Nadkarni, H. U. Bodeker, C. Beta, A. Bae, C. Franck, W. J. Rappel, W. F. Loomis, and E. Bodenschatz. 2006. Dictyostelium discoideum chemotaxis: threshold for directed motion. Eur. J. Cell Biol. In press.
50. Vicker, M. G. 2002. Eukaryotic cell locomotion depends on the propagation of self-organized reaction-diffusion waves and oscillations of actin filament assembly. Exp. Cell Res. 275:54-66.
51. Postma, M., J. Roelofs, J. Goedhart, T. W. J. Gadella, A. J. W. G. Visser, and P. J. M. Van Haastert. 2003. Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia. Mol. Biol. Cell. 14:5019-5027.
52. Mikhailov, A. S. 1996. Foundations of Synergetics. Springer, Berlin.
53. 3) is an activator of human neutrophil migration. FEBS Lett. 473:217-221.