Chemotaxis: Signalling modules join hands at front and tail

EMBO Reports

Volumn 5, Issue 1, 2004, Pages 35-40

  Postma, Marten ^a   Bosgraaf, Leonard ^a   Loovers, Harriët M ^a   Van Haastert, Peter J M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Actin; cGMP; Modules; Myosin; Ptdlns(3,4,5)P3

Indexed keywords

ACTIN; CYCLIC GMP; MYOSIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PLECKSTRIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN POLYMERIZATION; ARTICLE; CELL INTERACTION; CHEMOTAXIS; DICTYOSTELIUM; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PSEUDOPODIUM; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL SHAPE; CHEMOTAXIS; CYCLIC GMP; DICTYOSTELIUM; PHOSPHATIDYLINOSITOL PHOSPHATES; PSEUDOPODIA; SIGNAL TRANSDUCTION;

DICTYOSTELIUM; PSEUDOPODA;

EID: 1242298534     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400051     Document Type: Article

References (53)

1. Almeida PFF, Vaz WLC (1995) Lateral Diffusion in Membranes. Elsevier, Amsterdam, the Netherlands
2. Baggiolini M (1998) Chemokines and leukocyte traffic. Nature 392: 565-568
3. Berg HC (1988) A physicist looks at bacterial chemotaxis. Cold Spring Harb Symp Quant Biol 53: 1-9
4. Bosgraaf L, Russcher H, Smith JL, Wessels D, Soll DR, Van Haastert PJM (2002) A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J 21: 4560-4570
5. Bourne HR, Weiner O (2002) A chemical compass. Nature 419: 21
6. Bourret RB, Stock AM (2002) Molecular information processing: lessons from bacterial chemotaxis. J Biol Chem 277: 9625-9628
7. Campbell JJ, Butcher EC (2000) Chemokines in tissue-specific and microenvironment-specific lymphocyte homing, Curr Opin Immunol 12: 336-341
8. Chen C, Nakamura T, Koutalos Y (1999) Cyclic AMP diffusion coefficient in frog olfactory cilia. Biophys 176: 2861-2867
9. 3 accumulation and have unique roles during chemotaxis. Mol Biol Cell 14: 5028-5037
10. Chung CY, Firtel RA (1999) PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J Cell Biol 147: 559-576
11. Chung CY, Funamoto S, Firtel RA (2001a) Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci 26: 557-566
12. Chung CY, Potikyan G, Firtel RA (2001b) Control of cell polarity and chemotaxis by Akt/PKB a nd PI3 kinase through the regulation of PAKa. Mol Cell 7: 937-947
13. Crone SA, Lee KF (2002) The bound leading the bound: target-derived receptors act as guidance cues. Neuron 36: 333-335
14. de la Roche MA, Cote GP (2001) Regulation of Dictyostelium myosin I and II. Bochim Biophys Acta 1525: 245-261
15. 2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci 113: 1287-1298
16. Etienne-Manneville S, Hall A (2002) Rho GTPases in cell biology. Nature 420: 629-635
17. Funamoto S, Meili R, Lee S, Parry L, Firtel RA (2002) Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109: 611-623
18. Goldberg JM, Bosgaaf L, Van Haastert PJM, Smith L (2002) Identification of four candidate cGMP targets in Dictyostelium. Proc Natl Acad Sci USA 99: 6749-6754
19. Haugh JM, Lauffenburger DA (1997) Physical modulation of intracellular signaling processes by locational regulation. Biophys J 72: 2014-2031
20. Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, Wymann MP (2000) Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science 287: 1049-1053
21. 3 to the leading edge of chemotaxing cells. Mol Biol Cell 14: 1913-1922
22. Iijima M, Devreotes P (2002) Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109: 599-610
23. Iijima M, Huang YE, Devreotes P (2002) Temporal and spatial regulation of chemotaxis. Dev Cell 3: 469-78
24. Kriebel PW, Barr VA, Parent CA (2003) Adenylyl cyclase localization regulates streaming during chemotaxis. Cell 112: 549-560
25. Levchenko A, Iglesias PA (2002) Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils. Biophys J 82: 50-63
26. Liang W, Licate L, Warrick H, Spudich J, Egelhoff T (2002) Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration. BMC Cell Biol 3: 19
27. Liu G, Newell PC (1993) Role of cyclic GMP in signal transduction to cytoskeletal myosin. Symp Soc Exp Biol 47: 283-295
28. Loovers H, Veenstra K, Snippe H, Pesesse X, Erneux C, Van Haastert PJM (2002) A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum. J Biol Chem 278: 5652-5658
29. Mato JM, Losada A, Nanjundiah V, Konijn TM (1975) Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci USA 72: 4991-4993
30. Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, Firtel RA (1999) Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J 18: 2092-2105
31. Meinhardt H, Gierer A (2000) Pattern formation by local self-activation and lateral inhibition. BioEssays 22: 753-760
32. Parent CA, Devreotes PN (1999) A cell's sense of direction. Science 284: 765-770
33. Parent CA, Blacklock BJ, Froehlich WM, Murphy DB, Devreotes PN (1998) G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95: 81-91
34. Pollard TD, Borisy GG (2003) Cellular motility driven by assembly and disassembly of actin filaments. Cell 112: 453-465
35. Postma M, Van Haastert PJM (2001) A diffusion-translocation model for gradient sensing by chemotactic cells. Biophys J 81: 1314-1323
36. Postma M, Roelofs J, Goedhart J, Gadella TWJ, Visser AJWG, Van Haastert PJM (2003) Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia. Mol Biol Cell 14: 5019-5027
37. Potma EO, de Boeij WP, Bosgraaf L, Roelofs J, Van Haastert PJM, Wiersma DA (2001) Reduced protein diffusion rate by cytoskeleton in vegetative and polarized Dictyostelium cells. Biophys J 81: 2010-2019
38. Roelofs J, Smith JL, Van Haastert PJM (2002) cGMP signalling: different ways to create a pathway. Trends Genet 19: 132-134
39. Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Bourne HR (2000) Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 287: 1037-1040
40. 3 and polarity during neutrophil chemotaxis. J Cell Biol 160: 375-385
41. Steimle PA, Licate L, Cote GP, Egelhoff TT (2002) Lamellipodial localization of Dictyostelium myosin heavy chain kinase A is mediated via F-actin binding by the coiled-coil domain. FEBS Lett 516: 58-62
42. Stites J, Wessels D, Uhl A, Egelhoff T, Shutl D, Soll DR (1998) Phosphorylation of the Dictyostelium myosin II heavy chain is necessary for maintaining cellular polarity and suppressing turning during chemotaxis. Cell Motil Cytoskel 39: 31-51
43. Swanson JA, Taylor DL (1982) Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis. Cell 28: 225-232
44. Traynor-Kaplan AE, Thompson BL, Harris AL, Taylor P, Omann GM, Sklar LA (1989) Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils. J Biol Chem 264: 15668-15673
45. Ueda M, Sako Y, Tanaka T, Devreotes P, Yanagida T (2001) Single-molecule analysis of chemotactic signaling in Dictyostelium cells. Science 294: 864-867
46. Valkema R, Van Haastert PJM (1994) A model for cAMP-mediated cGMP response in Dictyostelium discoideum. Mol Biol Cell 5: 575-585
47. Van Haastert PJM, Van der Heijden PR (1983) Excitation, adaptation, and deadaptation of the cAMP-mediated cGMP response in Dictyostelium discoideum. J Cell Biol 96: 347-353
48. Van Haastert PJM, de Wit RJ, Janssens PM, Kesbeke F, DeGoede J (1986) G-protein-mediated interconversions of cell-surface cAMP receptors and their involvement in excitation and desensitization of guanylate cyclase in Dictyostelium discoideum. J Biol Chem 261: 6904-6911
49. Wang F, Herzmark P, Weiner OD, Srinivasan S, Servant G, Bourne HR (2002) Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nature Cell Biol 4: 513-518
50. Wessels D, Soll DR, Knecht D, Loomis WF, De Lozanne A, Spudich J (1988) Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Dev Biol 128: 164-177
51. Xu J, Wang F, Van Keymeulen A, Herzmark P, Straight A, Kelly K, Takuwa Y, Sugimoto N, Mitchison T, Bourne HR (2003) Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114: 201-214
52. Zhou K, Takegawa K, Emr SD, Firtel RA (1995) A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol Cell Biol 15: 5645-5656
53. Zigmond SH (1977) Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors. J Cell Biol 75: 606-616