3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE

Journal of Autoimmunity

Volumn 27, Issue 4, 2006, Pages 251-265

  Mix, Eilhard ^a   Ibrahim, Saleh M ^a   Pahnke, Jens ^a   Glass, Änne ^a   Mazón Peláez, Ignacio ^a   Lemcke, Susanne ^a   Koczan, Dirk ^a   Gimsa, Ulrike ^a   Bansemer, Sven ^a   Scheel, Thomas ^a   Karopka, Thomas ^a   Böttcher, Tobias ^a   Müller, Jana ^a   Dazert, Eike ^b   Antipova, Veronica ^a   Hoffrogge, Raimund ^a   Wree, Andreas ^a   Zschiesche, Marlies ^a   Strauß, Ulf ^a   Kundt, Günther ^a   Warzok, Rolf ^b   Gierl, Lothar ^a   Rolfs, Arndt ^a   more..

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Experimental autoimmune encephalomyelitis (EAE); Immunohistochemistry; Leukocyte subpopulations; Lymph nodes; Oligonucleotide microarray; Spinal cord; Statin; Western blot

Indexed keywords

ATORVASTATIN; CD86 ANTIGEN; CYCLOOXYGENASE 1; FREUND ADJUVANT; HEAT SHOCK PROTEIN 105; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; PROTEOLIPID PROTEIN; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL ACTIVATION; CELL FUNCTION; CELL INTERACTION; CONTROLLED STUDY; DISEASE COURSE; DNA MICROARRAY; DRUG EFFECT; DRUG RESPONSE; FLOW CYTOMETRY; GENE EXPRESSION; HELPER CELL; IMMUNIZATION; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPH NODE CELL; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MALE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REMISSION; SPINAL CORD; SWISS JAMES LAMBERT MOUSE; TARGET CELL; WESTERN BLOTTING;

ANIMALS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; GENE EXPRESSION; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUKOCYTES; LYMPH NODES; MALE; MICE; MULTIPLE SCLEROSIS; MYELIN PROTEOLIPID PROTEIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; PYRROLES; SPINAL CORD;

EID: 33846703735     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2006.09.006     Document Type: Article

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