-
1
-
-
0029114427
-
Copolymer 1: A most reasonable alternative therapy for early relapsing-remitting multiple sclerosis with mild disability
-
(1995)
Neurology
, vol.45
, pp. 1245-1247
-
-
Wolinsky, J.S.1
-
2
-
-
0033600078
-
Progress in determining the causes and treatment of multiple sclerosis
-
(1999)
Nature
, vol.399
, Issue.SUPPL.
-
-
Noseworthy, J.H.1
-
3
-
-
0032893142
-
Glatiramer acetate or interferon-β for multiple sclerosis? A guide to drug choice
-
(1999)
CNS Drugs
, vol.11
, pp. 289-306
-
-
Milo, R.1
Panitch, H.2
-
4
-
-
0001925434
-
Glatiramer acetate
-
Hawkins CP, Wolinsky JS, eds. Principles of treatments in multiple sclerosis. Oxford, Woburn: Butterworth-Heinemann
-
(2000)
, pp. 71-94
-
-
Wolinsky, J.S.1
-
5
-
-
0029936443
-
New insights into the mechanism of action of copolymer 1 in experimental allergic encephalomyelitis and multiple sclerosis
-
(1996)
J Neurol
, vol.243
, Issue.SUPPL. 1
-
-
Arnon, R.1
Sela, M.2
Teitelbaum, D.3
-
6
-
-
0030013545
-
The development of Cop-1 (Copaxone®), an innovative drug for the treatment of multiple sclerosis: Personal reflections
-
(1996)
Immunol Lett
, vol.50
, pp. 1-15
-
-
Arnon, R.1
-
13
-
-
0029986881
-
The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: Effect of copolymer 1 on MOG-induced disease
-
(1996)
J Neurol
, vol.243
, Issue.SUPPL. 1
-
-
Ben-Nun, A.1
Mendel, I.2
Bakimer, R.3
-
14
-
-
0029978508
-
A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5061-5066
-
-
Schlegel, P.G.1
Aharoni, R.2
Chen, Y.3
-
20
-
-
0029082566
-
Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis. Results of a phase III multicenter, double-blind, placebo-controlled trial
-
(1995)
Neurology
, vol.45
, pp. 1268-1276
-
-
Johnson, K.P.1
Brooks, B.R.2
Cohen, J.A.3
-
21
-
-
6844254570
-
Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability
-
(1998)
Neurology
, vol.50
, pp. 701-708
-
-
Johnson, K.P.1
Brooks, B.R.2
Cohen, J.A.3
-
22
-
-
0000093080
-
The effect of glatiramer acetate (Copaxone®) on disease activity as measured by cerebral MRI in patients with relapsing-remitting multiple sclerosis (RRMS): A multi-center, randomized, double blind, placebo-controlled study extended by open-label treatment
-
Abstract
-
(1999)
Neurology
, vol.52
, Issue.SUPPL. 2
-
-
Comi, G.1
Filippi, M.2
-
25
-
-
0032111406
-
Probing into the realm of proteins and immunity
-
(1998)
Protein Sci
, vol.7
, pp. 1653-1659
-
-
Sela, M.1
-
33
-
-
0027397577
-
T suppressor hybridomas and interleukin-2 dependent lines induced by copolymer 1 or by spinal cord homogenate down-regulate experimental allergic encephalomyelitis
-
(1993)
Eur J Immunol
, vol.23
, pp. 17-25
-
-
Aharoni, R.1
Teitelbaum, D.2
Arnon, R.3
-
45
-
-
0000316952
-
The lymphocyte proliferative response to glatiramer acetate in normal humans is dependent on both major histocompatibility complex (MHC)
-
Abstract
-
(2000)
J Neurol
, vol.247
, Issue.SUPPL. 3
-
-
Ragheb, S.1
Lisak, R.P.2
-
47
-
-
0005628335
-
Effect of treatment of patients with glatiramer acetate (copolymer-1) on the proliferative response of peripheral blood mononuclear cells to glatiramer acetate in vitro
-
Abstract
-
(1999)
Ann Neurol
, vol.46
, pp. 457
-
-
Ragheb, S.1
Abramczk, S.2
Lisak, R.P.3
-
56
-
-
0343006716
-
Glatiramer acetate (Copolymer-1)-specific, human T cell lines: Cytokine profile and suppression of T cell lines reactive against myelin basic protein (MBP)
-
(2000)
Neurosci Lett
, vol.289
, pp. 205-208
-
-
Dabbert, D.1
Rösner, S.2
Krämer, M.3
-
65
-
-
0034678450
-
Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
-
(2000)
J Exp Med
, vol.191
, pp. 1395-1412
-
-
Krogsgaard, M.1
Wucherpfennig, K.W.2
Canella, B.3
-
66
-
-
0033152935
-
Clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors
-
(1999)
J Immunol
, vol.162
, pp. 6303-6306
-
-
Besser, M.1
Wank, R.2
-
67
-
-
0030847054
-
Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
-
(1997)
Immunol Today
, vol.19
, pp. 335-343
-
-
Weiner, H.L.1
-
68
-
-
0030989875
-
Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
-
(1997)
Brain
, vol.120
, pp. 865-916
-
-
Hohlfeld, R.1
-
69
-
-
0028926223
-
Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
-
(1995)
Cell
, vol.80
, pp. 695-705
-
-
Wucherpfennig, K.W.1
Strominger, J.L.2
-
77
-
-
0028842529
-
Interferon (IFN) β acts downstream of IFN-γ-induced class II transactivator messenger RNA accumulation to block histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-γ
-
(1995)
J Exp Med
, vol.182
, pp. 1517-1525
-
-
Lu, H.T.1
Riley, J.L.2
Babcock, G.T.3
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