메뉴 건너뛰기




Volumn 1135, Issue 1, 2007, Pages 92-101

NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice

Author keywords

Dorsal horn neuron; Neuropathic pain; NMDA receptor; NR2B subunit; Single cell RT PCR; Spinal cord

Indexed keywords

IFENPRODIL; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

EID: 33846616938     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.12.014     Document Type: Article
Times cited : (57)

References (42)
  • 1
    • 0033962090 scopus 로고    scopus 로고
    • Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord
    • Baba H., Doubell T.P., Moore K.A., and Woolf C.J. Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord. J. Neurophysiol. 83 (2000) 955-962
    • (2000) J. Neurophysiol. , vol.83 , pp. 955-962
    • Baba, H.1    Doubell, T.P.2    Moore, K.A.3    Woolf, C.J.4
  • 2
    • 0032529597 scopus 로고    scopus 로고
    • NMDA EPSCs at glutamatergic synapses in the spinal cord dorsal horn of the postnatal rat
    • Bardoni R., Magherini P.C., and DacDermott A.B. NMDA EPSCs at glutamatergic synapses in the spinal cord dorsal horn of the postnatal rat. J. Neurosci. 18 (1998) 6558-6567
    • (1998) J. Neurosci. , vol.18 , pp. 6558-6567
    • Bardoni, R.1    Magherini, P.C.2    DacDermott, A.B.3
  • 3
    • 0034678026 scopus 로고    scopus 로고
    • Intrathecal administration of an NMDA and non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury
    • Bennett A.D., Everhart A.W., and Hulsebosch C.E. Intrathecal administration of an NMDA and non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain Res. 859 (2000) 72-82
    • (2000) Brain Res. , vol.859 , pp. 72-82
    • Bennett, A.D.1    Everhart, A.W.2    Hulsebosch, C.E.3
  • 4
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S., Wyatt A., Webb J.K., O'Donnell R., Mason G., Rigby M., Sirinathsinghji D., Hill R.G., and Rupniak N.M.J. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 38 (1999) 611-623
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3    O'Donnell, R.4    Mason, G.5    Rigby, M.6    Sirinathsinghji, D.7    Hill, R.G.8    Rupniak, N.M.J.9
  • 5
    • 0034663159 scopus 로고    scopus 로고
    • Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses
    • Cathala L., Misra C., and Cull-Candy S.G. Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses. J. Neurosci. 20 (2000) 5899-5905
    • (2000) J. Neurosci. , vol.20 , pp. 5899-5905
    • Cathala, L.1    Misra, C.2    Cull-Candy, S.G.3
  • 6
    • 0035218071 scopus 로고    scopus 로고
    • Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil
    • Chizh B.A., Reissmueller E., Schluetz H., Scheede M., Haase G., and Englberger W. Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil. Neuropharmacology 40 (2001) 212-220
    • (2001) Neuropharmacology , vol.40 , pp. 212-220
    • Chizh, B.A.1    Reissmueller, E.2    Schluetz, H.3    Scheede, M.4    Haase, G.5    Englberger, W.6
  • 7
    • 16544376850 scopus 로고    scopus 로고
    • Role of distinct NMDA receptor subtypes at central synapses
    • Cull-Candy S.G., and Leszkiewicz D.N. Role of distinct NMDA receptor subtypes at central synapses. Science STKE 255 (2004) re16
    • (2004) Science STKE , vol.255
    • Cull-Candy, S.G.1    Leszkiewicz, D.N.2
  • 9
    • 0026500432 scopus 로고
    • Activity dependent neuronal plasticity following tissue injury and inflammation
    • Dubner R., and Ruda M.A. Activity dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15 (1992) 96-103
    • (1992) Trends Neurosci. , vol.15 , pp. 96-103
    • Dubner, R.1    Ruda, M.A.2
  • 10
    • 0037374587 scopus 로고    scopus 로고
    • Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
    • Ehlers M. Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat. Neurosci. 6 (2003) 231-242
    • (2003) Nat. Neurosci. , vol.6 , pp. 231-242
    • Ehlers, M.1
  • 11
    • 0030909728 scopus 로고    scopus 로고
    • NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex
    • Flint A.C., Maisch U.S., Weishaupt J.H., Kriegstein A.R., and Monyer H. NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex. J. Neurosci. 17 (1997) 2469-2476
    • (1997) J. Neurosci. , vol.17 , pp. 2469-2476
    • Flint, A.C.1    Maisch, U.S.2    Weishaupt, J.H.3    Kriegstein, A.R.4    Monyer, H.5
  • 12
    • 27844600582 scopus 로고    scopus 로고
    • Differential expression of NMDA receptor subunits between neurons containing and not containing enkephalin in the mouse embryo spinal cord
    • Fukushima T., Tomitori H., Iwata H., Maekawa M., and Hori Y. Differential expression of NMDA receptor subunits between neurons containing and not containing enkephalin in the mouse embryo spinal cord. Neurosci. Lett. 391 (2005) 11-16
    • (2005) Neurosci. Lett. , vol.391 , pp. 11-16
    • Fukushima, T.1    Tomitori, H.2    Iwata, H.3    Maekawa, M.4    Hori, Y.5
  • 13
    • 20444459753 scopus 로고    scopus 로고
    • Enhancement of NMDA receptor phosphorylation of the spinal dorsal horn and nucleus gracilis neurons in neuropathic rats
    • Gao X., Kim H.K., Chung J.M., and Chung K. Enhancement of NMDA receptor phosphorylation of the spinal dorsal horn and nucleus gracilis neurons in neuropathic rats. Pain 116 (2005) 62-72
    • (2005) Pain , vol.116 , pp. 62-72
    • Gao, X.1    Kim, H.K.2    Chung, J.M.3    Chung, K.4
  • 14
    • 0036389402 scopus 로고    scopus 로고
    • Formalin-induced changes of NMDA receptor subunit expression in the spinal cord of the rat
    • Gaunitz C., Schuttler A., Gillen C., and Allgaier C. Formalin-induced changes of NMDA receptor subunit expression in the spinal cord of the rat. Amino Acids 23 (2002) 177-182
    • (2002) Amino Acids , vol.23 , pp. 177-182
    • Gaunitz, C.1    Schuttler, A.2    Gillen, C.3    Allgaier, C.4
  • 15
    • 0035890288 scopus 로고    scopus 로고
    • Alteration in the voltage dependence of NMDA receptor channels in rat dorsal horn neurones following peripheral inflammation
    • Guo H., and Huang L.-Y.M. Alteration in the voltage dependence of NMDA receptor channels in rat dorsal horn neurones following peripheral inflammation. J. Physiol. 537 (2001) 115-123
    • (2001) J. Physiol. , vol.537 , pp. 115-123
    • Guo, H.1    Huang, L.-Y.M.2
  • 16
    • 0037101627 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia
    • Guo W., Zou S., Guan Y., Ikeda T., Tal M., Dubner R., and Ren K. Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. J. Neurosci. 22 (2002) 6208-6217
    • (2002) J. Neurosci. , vol.22 , pp. 6208-6217
    • Guo, W.1    Zou, S.2    Guan, Y.3    Ikeda, T.4    Tal, M.5    Dubner, R.6    Ren, K.7
  • 17
    • 0018956018 scopus 로고
    • Intrathecal morphine in mice: a new technique
    • Hylden J.L.K., and Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 67 (1980) 313-316
    • (1980) Eur. J. Pharmacol. , vol.67 , pp. 313-316
    • Hylden, J.L.K.1    Wilcox, G.L.2
  • 18
    • 0034521340 scopus 로고    scopus 로고
    • Facilitation of NMDA-induced currents and Ca2+ transients in the rat substantia gelatinosa neurons after ligation of L5-L6 spinal nerves
    • Isaev D., Gerber G., Park S.K., Chung J.M., and Randic M. Facilitation of NMDA-induced currents and Ca2+ transients in the rat substantia gelatinosa neurons after ligation of L5-L6 spinal nerves. NeuroReport 11 (2000) 4055-4061
    • (2000) NeuroReport , vol.11 , pp. 4055-4061
    • Isaev, D.1    Gerber, G.2    Park, S.K.3    Chung, J.M.4    Randic, M.5
  • 19
    • 0037135250 scopus 로고    scopus 로고
    • Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn-effects of peripheral nerve lesion and inflammation
    • Karlsson U., Sjoedin J., Moeller A., Johansson S., Wikstroem L., and Naesstroem J. Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn-effects of peripheral nerve lesion and inflammation. Neuroscience 112 (2002) 861-868
    • (2002) Neuroscience , vol.112 , pp. 861-868
    • Karlsson, U.1    Sjoedin, J.2    Moeller, A.3    Johansson, S.4    Wikstroem, L.5    Naesstroem, J.6
  • 20
    • 0030450983 scopus 로고    scopus 로고
    • A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones
    • Kew J.N.C., Trube G., and Kemp J.A. A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones. J. Physiol. 497 (1996) 761-772
    • (1996) J. Physiol. , vol.497 , pp. 761-772
    • Kew, J.N.C.1    Trube, G.2    Kemp, J.A.3
  • 21
    • 1342308188 scopus 로고    scopus 로고
    • Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity
    • Kiyosue K., Hiyama T.Y., Nakayama K., Kasai M., and Taguchi T. Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity. Int. J. Dev. Neurosci. 22 (2004) 59-65
    • (2004) Int. J. Dev. Neurosci. , vol.22 , pp. 59-65
    • Kiyosue, K.1    Hiyama, T.Y.2    Nakayama, K.3    Kasai, M.4    Taguchi, T.5
  • 22
    • 0034177708 scopus 로고    scopus 로고
    • Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum
    • Misra C., G. B.S., Farrant M., and Cull-Candy S.G. Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum. J. Physiol. 524 (2000) 147-162
    • (2000) J. Physiol. , vol.524 , pp. 147-162
    • Misra, C.1    G., B.S.2    Farrant, M.3    Cull-Candy, S.G.4
  • 23
    • 0034653985 scopus 로고    scopus 로고
    • Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord
    • Momiyama A. Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord. J. Physiol. 523 (2000) 621-628
    • (2000) J. Physiol. , vol.523 , pp. 621-628
    • Momiyama, A.1
  • 25
    • 10944258479 scopus 로고    scopus 로고
    • Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-d-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking technique
    • Nagy G.G., Watanabe M., Fukaya M., and Todd A.J. Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-d-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking technique. Eur. J. Neurosci. 20 (2004) 3301-3312
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 3301-3312
    • Nagy, G.G.1    Watanabe, M.2    Fukaya, M.3    Todd, A.J.4
  • 27
    • 0027234701 scopus 로고
    • The molecular biology of mammalian glutamate receptor channels
    • Seeburg P.H. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 16 (1993) 359-365
    • (1993) Trends Neurosci. , vol.16 , pp. 359-365
    • Seeburg, P.H.1
  • 28
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders, produce din rats by partial sciatic nerve injury
    • Seltzer Z., Dubner R., and Shir Y. A novel behavioral model of neuropathic pain disorders, produce din rats by partial sciatic nerve injury. Pain 43 (1990) 205-218
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 29
    • 0035958681 scopus 로고    scopus 로고
    • Developmental regulation of N-methyl-d-aspartate - and kainate-type glutamate receptor expression in the spinal cord
    • Stegena S.L., and Kalb R.G. Developmental regulation of N-methyl-d-aspartate - and kainate-type glutamate receptor expression in the spinal cord. Neuroscience 105 (2001) 499-507
    • (2001) Neuroscience , vol.105 , pp. 499-507
    • Stegena, S.L.1    Kalb, R.G.2
  • 30
    • 11844283922 scopus 로고    scopus 로고
    • Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat
    • Tan P.-H., Yang L.-C., Shih H.-C., Lan K.-C., and Cheng J.-T. Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat. Gene Ther. 12 (2005) 59-66
    • (2005) Gene Ther. , vol.12 , pp. 59-66
    • Tan, P.-H.1    Yang, L.-C.2    Shih, H.-C.3    Lan, K.-C.4    Cheng, J.-T.5
  • 33
    • 0033539007 scopus 로고    scopus 로고
    • Enkephalinergic neurons express 5-HT3 receptors in the spinal cord dorsal horn: single cell RT-PCR analysis
    • Tsuchiya M., Yamazaki H., and Hori Y. Enkephalinergic neurons express 5-HT3 receptors in the spinal cord dorsal horn: single cell RT-PCR analysis. NeuroReport 10 (1999) 2749-2753
    • (1999) NeuroReport , vol.10 , pp. 2749-2753
    • Tsuchiya, M.1    Yamazaki, H.2    Hori, Y.3
  • 35
    • 0035808617 scopus 로고    scopus 로고
    • Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-d-aspartate receptor-mediated transmission in mutant mice lacking d-amino-acid oxidase
    • Wake K., Yamazaki H., Hanzawa S., Konno R., Sakio H., Niwa A., and Hori Y. Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-d-aspartate receptor-mediated transmission in mutant mice lacking d-amino-acid oxidase. Neurosci. Lett. 297 (2001) 25-28
    • (2001) Neurosci. Lett. , vol.297 , pp. 25-28
    • Wake, K.1    Yamazaki, H.2    Hanzawa, S.3    Konno, R.4    Sakio, H.5    Niwa, A.6    Hori, Y.7
  • 36
    • 0027092373 scopus 로고
    • Developmental changes in distribution of NMDA receptor channel subunit mRNAs
    • Watanabe M., Inoue Y., Sakimura K., and Mishina M. Developmental changes in distribution of NMDA receptor channel subunit mRNAs. NeuroReport 3 (1992) 1138-1140
    • (1992) NeuroReport , vol.3 , pp. 1138-1140
    • Watanabe, M.1    Inoue, Y.2    Sakimura, K.3    Mishina, M.4
  • 37
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states
    • Woolf C.J., and Thompson S.W. The induction and maintenance of central sensitization is dependent on N-methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 44 (1991) 293-299
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 38
    • 0001823013 scopus 로고    scopus 로고
    • Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
    • Wyllie D.J., Behe P., and Colquhoun D. Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. J. Physiol. 510 (1998) 1-18
    • (1998) J. Physiol. , vol.510 , pp. 1-18
    • Wyllie, D.J.1    Behe, P.2    Colquhoun, D.3
  • 39
    • 0025948539 scopus 로고
    • Suppression of neuropathic pain behavior in rats by a non-psychotropic synthetic cannabinoid with NMDA receptor-blocking properties
    • Zeltser R., Seltzer Z., Eisen A., Feigenbaum J.J., and Mechoulam R. Suppression of neuropathic pain behavior in rats by a non-psychotropic synthetic cannabinoid with NMDA receptor-blocking properties. Pain 47 (1991) 95-103
    • (1991) Pain , vol.47 , pp. 95-103
    • Zeltser, R.1    Seltzer, Z.2    Eisen, A.3    Feigenbaum, J.J.4    Mechoulam, R.5
  • 40
    • 0034041935 scopus 로고    scopus 로고
    • Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil
    • Zhang X.-X., Bunney B.S., and Shi W.-X. Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil. Synapse 37 (2000) 56-63
    • (2000) Synapse , vol.37 , pp. 56-63
    • Zhang, X.-X.1    Bunney, B.S.2    Shi, W.-X.3
  • 41
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1
  • 42
    • 0037049239 scopus 로고    scopus 로고
    • Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rat
    • Zou X., Lin Q., and Willis W.D. Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rat. Neuroscience 115 (2002) 775-786
    • (2002) Neuroscience , vol.115 , pp. 775-786
    • Zou, X.1    Lin, Q.2    Willis, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.