메뉴 건너뛰기




Volumn 258, Issue 2, 2000, Pages 374-383

Modulation of endogenous Smad expression in normal skin fibroblasts by transforming growth factor-β

Author keywords

Skin fibroblasts; Smad signaling; Smad3; Smad7; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 0034255634     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2000.4930     Document Type: Article
Times cited : (101)

References (54)
  • 1
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley D. M. The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8:1994;133-146.
    • (1994) Genes Dev. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 2
    • 0026560454 scopus 로고
    • TGF-beta: Regulation of extracellular matrix
    • Roberts A. B., McCune B. K., Sporn M. B. TGF-beta: Regulation of extracellular matrix. Kidney Int. 41:1992;557-559.
    • (1992) Kidney Int. , vol.41 , pp. 557-559
    • Roberts, A.B.1    McCune, B.K.2    Sporn, M.B.3
  • 3
    • 0028176086 scopus 로고
    • Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site
    • Inagaki Y., Truter S., Ramirez F. Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site. J. Biol. Chem. 269:1994;14828-14834.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14828-14834
    • Inagaki, Y.1    Truter, S.2    Ramirez, F.3
  • 4
    • 0028904803 scopus 로고
    • Requirements for transforming growth factor-β regulation of the pro-α2(I) collagen and plasminogen activator inhibitor-1 promoters
    • Chang E., Goldberg H. Requirements for transforming growth factor-β regulation of the pro-α2(I) collagen and plasminogen activator inhibitor-1 promoters. J. Biol. Chem. 270:1995;4473-4477.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4473-4477
    • Chang, E.1    Goldberg, H.2
  • 5
    • 0030047646 scopus 로고    scopus 로고
    • An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL1A2) promoter activity by transforming growth factor-β
    • Chung K. Y., Agarwal A., Uitto J., Mauviel A. An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL1A2) promoter activity by transforming growth factor-β J. Biol. Chem. 27:1996;3272-3278.
    • (1996) J. Biol. Chem. , vol.27 , pp. 3272-3278
    • Chung, K.Y.1    Agarwal, A.2    Uitto, J.3    Mauviel, A.4
  • 6
    • 0034011221 scopus 로고    scopus 로고
    • Interaction of Smad3 with a proximal Smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β
    • Chen S. J., Yuan W., Lo S., Trojanowska M., Varga J. Interaction of Smad3 with a proximal Smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β J. Cell. Physiol. 183:2000;381-392.
    • (2000) J. Cell. Physiol. , vol.183 , pp. 381-392
    • Chen, S.J.1    Yuan, W.2    Lo, S.3    Trojanowska, M.4    Varga, J.5
  • 7
    • 0028109801 scopus 로고
    • Transforming growth factor β in tissue fibrosis
    • Border W. A., Noble N. A. Transforming growth factor β in tissue fibrosis. N. Engl. J. Med. 331:1994;1286-1292.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 9
    • 0030846610 scopus 로고    scopus 로고
    • TGF-beta isoforms differentially attenuate EGF mitogenicity and receptor activity in fetal lung mesenchymal cells
    • Lee M., Hwang C., Lee J., Slavkin H., Warburton D. TGF-beta isoforms differentially attenuate EGF mitogenicity and receptor activity in fetal lung mesenchymal cells. Am. J. Physiol. 273:1997;L374-378.
    • (1997) Am. J. Physiol. , vol.273 , pp. 374-378
    • Lee, M.1    Hwang, C.2    Lee, J.3    Slavkin, H.4    Warburton, D.5
  • 10
    • 0030614553 scopus 로고    scopus 로고
    • TGF-beta3 stimulates and regulates collagen synthesis through TGF-beta1-dependent and independent mechanisms
    • Murata H., Zhou L., Ochoa S., Hasan A., Badiavas E., Falanga V. TGF-beta3 stimulates and regulates collagen synthesis through TGF-beta1-dependent and independent mechanisms. J. Invest. Dermatol. 108:1997;258-262.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 258-262
    • Murata, H.1    Zhou, L.2    Ochoa, S.3    Hasan, A.4    Badiavas, E.5    Falanga, V.6
  • 12
    • 0033573974 scopus 로고    scopus 로고
    • Smad6 suppresses TGF-β induced growth inhibition in COLO-357 pancreatic cancer cells and in overexpressed in pancreatic cancer
    • Kleeff J., Maruyama H., Friess H., Buchler M. W., Falb D., Korc M. Smad6 suppresses TGF-β induced growth inhibition in COLO-357 pancreatic cancer cells and in overexpressed in pancreatic cancer. Biochem. Biophys. Res. Commun. 255:1999;268-273.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 268-273
    • Kleeff, J.1    Maruyama, H.2    Friess, H.3    Buchler, M.W.4    Falb, D.5    Korc, M.6
  • 13
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signaling from cell membrane to nucleus through SMAD proteins
    • Heldin C.-H., Miyazono K., ten Dijke P. TGF-β signaling from cell membrane to nucleus through SMAD proteins. Nature. 390:1997;465-472.
    • (1997) Nature , vol.390 , pp. 465-472
    • Heldin, C.-H.1    Miyazono, K.2    Ten Dijke, P.3
  • 14
    • 0032442852 scopus 로고    scopus 로고
    • Smads: Transcriptional activators of TGF-β responses
    • Derynck R., Zhang Y., Feng X.-H. Smads: Transcriptional activators of TGF-β responses. Cell. 95:1998;737-740.
    • (1998) Cell , vol.95 , pp. 737-740
    • Derynck, R.1    Zhang, Y.2    Feng, X.-H.3
  • 15
    • 0030964105 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Signals, mechanisms and regulation
    • Nigg E. A. Nucleocytoplasmic transport: Signals, mechanisms and regulation. Nature. 386:1997;779-787.
    • (1997) Nature , vol.386 , pp. 779-787
    • Nigg, E.A.1
  • 16
    • 0033257926 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of TGF-β-activated Smad2
    • Lo R. S., Massague J. Ubiquitin-dependent degradation of TGF-β-activated Smad2. Nat. Cell Biol. 1:1999;472-478.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 472-478
    • Lo, R.S.1    Massague, J.2
  • 23
    • 0033527741 scopus 로고    scopus 로고
    • Smad7 differentially regulates transforming growth factor β-mediated signaling pathways
    • Zhu H.-J., Iaria J., Sizeland A. M. Smad7 differentially regulates transforming growth factor β-mediated signaling pathways. J. Biol. Chem. 274:1999;32258-32264.
    • (1999) J. Biol. Chem. , vol.274 , pp. 32258-32264
    • Zhu, H.-J.1    Iaria, J.2    Sizeland, A.M.3
  • 25
    • 0023631004 scopus 로고
    • Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts
    • Varga J., Rosenbloom J., Jimenez S. A. Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochem J. 247:1987;597-604.
    • (1987) Biochem J. , vol.247 , pp. 597-604
    • Varga, J.1    Rosenbloom, J.2    Jimenez, S.A.3
  • 26
    • 0030963943 scopus 로고    scopus 로고
    • DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells
    • de Winter J. P., Roelen B. A., ten Dijke P., van der Burg B., van den Eijnden-van Raaij A. J. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells. Oncogene. 14:1997;1891-1899.
    • (1997) Oncogene , vol.14 , pp. 1891-1899
    • De Winter, J.P.1    Roelen, B.A.2    Ten Dijke, P.3    Van Der Burg, B.4    Van Den Eijnden-Van Raaij, A.J.5
  • 27
    • 0022423245 scopus 로고
    • Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
    • Tso J. Y., Sun X. H., Kao T. H., Reece K. S., Wu R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13:1985;2485-2502.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 2485-2502
    • Tso, J.Y.1    Sun, X.H.2    Kao, T.H.3    Reece, K.S.4    Wu, R.5
  • 28
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-β response
    • Zhang Y., Feng X.-H., Wu R.-Y., Derynck R. Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature. 383:1996;168-171.
    • (1996) Nature , vol.383 , pp. 168-171
    • Zhang, Y.1    Feng, X.-H.2    Wu, R.-Y.3    Derynck, R.4
  • 31
    • 0007600705 scopus 로고
    • Isolation and characterization of cDNA clones for human and bovine fibronectin
    • Kornblihtt A. R., Vibe-Petersen K., Baralle F. E. Isolation and characterization of cDNA clones for human and bovine fibronectin. Proc. Natl. Acad. Sci. USA. 80:1983;3128-3222.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 3128-3222
    • Kornblihtt, A.R.1    Vibe-Petersen, K.2    Baralle, F.E.3
  • 32
    • 0028986030 scopus 로고
    • Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring
    • Shah M., Foreman D. M., Ferguson M. W. Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J. Cell Sci. 108:1995;985-1002.
    • (1995) J. Cell Sci. , vol.108 , pp. 985-1002
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.3
  • 34
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-beta/SMAD signaling by the interferon-gamma/STAT pathway
    • Ulloa L., Doody J., Massague J. Inhibition of transforming growth factor-beta/SMAD signaling by the interferon-gamma/STAT pathway. Nature. 397:1999;710-713.
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massague, J.3
  • 35
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S., Itoh S., Vivien D., ten Dijke P., Huet S., Gauthier J.-M. Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:1998;3091-3100.
    • (1998) EMBO J. , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.-M.6
  • 36
    • 0032742092 scopus 로고    scopus 로고
    • Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3
    • Song C. Z., Tian X., Gelehrter T. D. Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3. Proc. Natl. Acad. Sci. USA. 96:1999;11776-11781.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11776-11781
    • Song, C.Z.1    Tian, X.2    Gelehrter, T.D.3
  • 37
    • 0032437595 scopus 로고    scopus 로고
    • SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta
    • Vindevoghel L., Lechleider R. J., Kon A., de Caestecker M. P., Uitto J., Roberts A. B., Mauviel A. SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta. Proc. Natl. Acad. Sci. USA. 95:1998;14769-14774.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14769-14774
    • Vindevoghel, L.1    Lechleider, R.J.2    Kon, A.3    De Caestecker, M.P.4    Uitto, J.5    Roberts, A.B.6    Mauviel, A.7
  • 38
    • 0032824798 scopus 로고    scopus 로고
    • The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells
    • Poncelet A. C., De Caestecker M. P., Schnaper H. W. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells. Kidney Int. 56:1999;1354-1365.
    • (1999) Kidney Int. , vol.56 , pp. 1354-1365
    • Poncelet, A.C.1    De Caestecker, M.P.2    Schnaper, H.W.3
  • 39
    • 0032192236 scopus 로고    scopus 로고
    • Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-β In human normal lung epithelial cells
    • Yanagasawa K., Osada H., Masuda A., Kondo M., Saito T., Yatabe Y., Takagi K., Takahashi T., Takahashi T. Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-β in human normal lung epithelial cells. Oncogene. 17:1998;1743-1747.
    • (1998) Oncogene , vol.17 , pp. 1743-1747
    • Yanagasawa, K.1    Osada, H.2    Masuda, A.3    Kondo, M.4    Saito, T.5    Yatabe, Y.6    Takagi, K.7    Takahashi, T.8    Takahashi, T.9
  • 40
    • 2442724379 scopus 로고
    • Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
    • Edwards D. R., Murphy G., Reynolds J. J., Whitheam S. E., Docherty A. J. P., Angel P., Heath J. K. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 6:1987;1899-1904.
    • (1987) EMBO J. , vol.6 , pp. 1899-1904
    • Edwards, D.R.1    Murphy, G.2    Reynolds, J.J.3    Whitheam, S.E.4    Docherty, A.J.P.5    Angel, P.6    Heath, J.K.7
  • 41
    • 0031049923 scopus 로고    scopus 로고
    • Transforming growth factor β1 inhibits collagenase 3 expression by transcriptional and post-transcriptional mechanisms in osteoblast cultures
    • Rydziel S., Varghese S., Canalis E. Transforming growth factor β1 inhibits collagenase 3 expression by transcriptional and post-transcriptional mechanisms in osteoblast cultures. J. Cell. Physiol. 170:1997;145-152.
    • (1997) J. Cell. Physiol. , vol.170 , pp. 145-152
    • Rydziel, S.1    Varghese, S.2    Canalis, E.3
  • 42
    • 0031065145 scopus 로고    scopus 로고
    • TGF-beta attenuates the class II transactivator and reveals accessory pathway of IFN-gamma action
    • Nandan D., Reiner N. E. TGF-beta attenuates the class II transactivator and reveals accessory pathway of IFN-gamma action. J. Immunol. 158:1997;1095-10101.
    • (1997) J. Immunol. , vol.158 , pp. 1095-10101
    • Nandan, D.1    Reiner, N.E.2
  • 43
    • 0030772028 scopus 로고    scopus 로고
    • Down-regulation of the cyclin A promoter by transforming growth factor-β1 is associated with a reduction in phosphorylated activating transcription factor-1 and cyclic AMP-responsive element-binding protein
    • Yoshizumi M., Wang H., Hsieh C.-M., Sibinga E. S., Perrella M. A., Lee M.-E. Down-regulation of the cyclin A promoter by transforming growth factor-β1 is associated with a reduction in phosphorylated activating transcription factor-1 and cyclic AMP-responsive element-binding protein. J. Biol. Chem. 272:1997;22259-22264.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22259-22264
    • Yoshizumi, M.1    Wang, H.2    Hsieh, C.-M.3    Sibinga, E.S.4    Perrella, M.A.5    Lee, M.-E.6
  • 44
    • 8944222110 scopus 로고    scopus 로고
    • Stimulus-specific inhibition of intercellular adhesion molecule-1 gene expression by TGF-β1
    • Shirkant P., Lee S. J., Kalvakolanu I., Ransohoff R. M., Benveniste E. N. Stimulus-specific inhibition of intercellular adhesion molecule-1 gene expression by TGF-β1. J. Immunol. 157:1996;892-900.
    • (1996) J. Immunol. , vol.157 , pp. 892-900
    • Shirkant, P.1    Lee, S.J.2    Kalvakolanu, I.3    Ransohoff, R.M.4    Benveniste, E.N.5
  • 45
    • 17544372403 scopus 로고    scopus 로고
    • Transforming growth factor β1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells
    • Mandriota S. J., Menoud P.-A., Pepper M. S. Transforming growth factor β1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells. J. Biol. Chem. 271:1996;11500-11505.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11500-11505
    • Mandriota, S.J.1    Menoud, P.-A.2    Pepper, M.S.3
  • 46
    • 0032803878 scopus 로고    scopus 로고
    • Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway
    • Warner B. J., Blain S. W., Seoane J., Massague J. Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway. Mol. Cell. Biol. 19:1999;5913-5922.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5913-5922
    • Warner, B.J.1    Blain, S.W.2    Seoane, J.3    Massague, J.4
  • 47
    • 0033104505 scopus 로고    scopus 로고
    • TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
    • Hocever B. A., Brown T. L., Howe P. H. TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 18:1999;1345-1356.
    • (1999) EMBO J. , vol.18 , pp. 1345-1356
    • Hocever, B.A.1    Brown, T.L.2    Howe, P.H.3
  • 48
    • 0033584854 scopus 로고    scopus 로고
    • Regulation of Smad7 promoter by direct association with Smad3 and Smad4
    • Nagarajan R. P., Zhang J., Li W., Chen Y. Regulation of Smad7 promoter by direct association with Smad3 and Smad4. J. Biol. Chem. 274:1999;33412-33418.
    • (1999) J. Biol. Chem. , vol.274 , pp. 33412-33418
    • Nagarajan, R.P.1    Zhang, J.2    Li, W.3    Chen, Y.4
  • 50
    • 0032587028 scopus 로고    scopus 로고
    • Negative modulation of α1(I) procollagen gene expression in human skin fibroblasts: Transcriptional inhibition by interferon-gamma
    • Yuan W., Yufit T., Li L., Mori Y., Chen S. J., Varga J. Negative modulation of α1(I) procollagen gene expression in human skin fibroblasts: Transcriptional inhibition by interferon-gamma. J. Cell. Physiol. 179:1999;97-108.
    • (1999) J. Cell. Physiol. , vol.179 , pp. 97-108
    • Yuan, W.1    Yufit, T.2    Li, L.3    Mori, Y.4    Chen, S.J.5    Varga, J.6
  • 52
    • 0032909167 scopus 로고    scopus 로고
    • FAST-2 is a mammalian winged-helix protein which mediated transforming growth factor beta signals
    • Liu B., Dou C. L., Prabhu L., Lai E. FAST-2 is a mammalian winged-helix protein which mediated transforming growth factor beta signals. Mol. Cell. Biol. 19:1999;424-430.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 424-430
    • Liu, B.1    Dou, C.L.2    Prabhu, L.3    Lai, E.4
  • 53
    • 0032191407 scopus 로고    scopus 로고
    • Synergistic cooperation of TFE3 and smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene
    • Hua X., Liu X., Ansari D. O., Lodish H. F. Synergistic cooperation of TFE3 and smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene. Genes Dev. 12:1998;3084-3095.
    • (1998) Genes Dev. , vol.12 , pp. 3084-3095
    • Hua, X.1    Liu, X.2    Ansari, D.O.3    Lodish, H.F.4
  • 54
    • 0032527756 scopus 로고    scopus 로고
    • TGF-beta-stimulated cooperation of Smad proteins with the coactivators CBP/p300
    • Janknecht R., Wells N. J., Hunter T. TGF-beta-stimulated cooperation of Smad proteins with the coactivators CBP/p300. Genes Dev. 12:1998;2114-2119.
    • (1998) Genes Dev. , vol.12 , pp. 2114-2119
    • Janknecht, R.1    Wells, N.J.2    Hunter, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.