Structural understanding of efflux-mediated drug resistance: Potential routes to efflux inhibition

Current Opinion in Pharmacology

Volumn 4, Issue 5, 2004, Pages 479-486

  McKeegan, Kenneth S ^a   Borges Walmsley, M Ines ^a   Walmsley, Adrian R ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTHRACYCLINE; CYANOCOBALAMIN; CYCLOSPORIN A; CYTOTOXIC AGENT; DAUNORUBICIN; DOXORUBICIN; EPIGALLOCATECHIN GALLATE; GLYCEROPHOSPHATE; GLYCOPROTEIN P; GREEN TEA EXTRACT; LACTOSE; LEVOFLOXACIN; MACROLIDE; MC 02595; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PHENYLALANYLARGININE 2 NAPHTHYLAMIDE; PYRROLE DERIVATIVE; QUINIDINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RESERPINE; SODIUM PROTON EXCHANGE PROTEIN; STIBOGLUCONATE SODIUM; TAMOXIFEN; TOBRAMYCIN; TOREMIFENE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; YOHIMBINE; ANTIPORTER;

ARTICLE; BACTERIAL INFECTION; BINDING SITE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG TRANSPORT; EUKARYOTIC CELL; HUMAN; HYPERTENSION; MALIGNANT NEOPLASTIC DISEASE; MULTIDRUG RESISTANCE; MYCOSIS; PRIORITY JOURNAL; PROKARYOTIC CELL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTOZOAL INFECTION; PUMP; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; PHYSIOLOGY; REVIEW; X RAY CRYSTALLOGRAPHY;

ANTIPORTERS; ATP-BINDING CASSETTE TRANSPORTERS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, MULTIPLE; HUMANS; MODELS, MOLECULAR; P-GLYCOPROTEIN; SODIUM-HYDROGEN ANTIPORTER;

EID: 9644305640     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2004.07.002     Document Type: Review

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