Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas

Journal of Pathology

Volumn 202, Issue 4, 2004, Pages 412-420

  Reinacher Schick, Anke ^a   Baldus, Stephan E ^b   Romdhana, Bashra ^a   Landsberg, Stephanie ^b   Zapatka, Mark ^a   Mönig, Stefan P ^b   Hölscher, Arnulf H ^b   Dienes, Hans P ^b   Schmiegel, Wolff ^a   Schwarte Waldhoff, Irmgard ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

E cadherin; Intercellular adhesion; P cadherin; Regulator of invasion; Smad4; TGF ; Tumour suppressor gene

Indexed keywords

CADHERIN; CATENIN; RNA; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN; UVOMORULIN;

ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CARCINOGENESIS; CELL ADHESION; CELL STRUCTURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; CORRELATION ANALYSIS; EPITHELIOID CELL; GENE LOSS; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MEDICAL ASSESSMENT; METASTASIS POTENTIAL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

BETA CATENIN; CADHERINS; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; SMAD4 PROTEIN; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 11144358223     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1516     Document Type: Article

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