Effects of antioxidants on auditory nerve function and survival in deafened guinea pigs

Neurobiology of Disease

Volumn 25, Issue 2, 2007, Pages 309-318

  Maruyama, Jun ^a,b   Yamagata, Takahiko ^a,b   Ulfendahl, Mats ^a   Bredberg, Göran ^c   Altschuler, Richard A ^d   Miller, Josef M ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Ascorbic acid; Deafferentation; Electrical auditory brainstem response; Spiral ganglion cell; Trolox; Vitamin C; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; NEUROTROPHIC FACTOR; TROLOX C; WATER;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY RESPONSE; CELL DESTRUCTION; CELL SURVIVAL; COCHLEAR NERVE; CONTROLLED STUDY; DEAFFERENTATION; DRUG ADMINISTRATION ROUTE; DRUG MEGADOSE; EVOKED BRAIN STEM AUDITORY RESPONSE; GUINEA PIG; HEARING IMPAIRMENT; IN VITRO STUDY; IN VIVO STUDY; INTRACOCHLEAR DRUG ADMINISTRATION; MALE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NERVE FUNCTION; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPIRAL GANGLION;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; AUDITORY THRESHOLD; CELL SURVIVAL; CHROMANS; COCHLEAR NERVE; DEAFNESS; DENERVATION; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GUINEA PIGS; HAIR CELLS; HEARING LOSS, SENSORINEURAL; MALE; NEURONS, AFFERENT; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; SPIRAL GANGLION; TREATMENT OUTCOME;

EID: 33846318936     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.09.012     Document Type: Article

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