BDNF protection of auditory neurons from cisplatin involves changes in intracellular levels of both reactive oxygen species and glutathione

Molecular Brain Research

Volumn 50, Issue 1-2, 1997, Pages 71-78

  Gabaizadeh, R ^a   Staecker, H ^a   Liu, W ^a   Van De Water, T R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Auditory neuron; Cisplatin neurotoxicity; Glutathione; Reactive oxygen species

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BUTHIONINE SULFOXIMINE; CISPLATIN; GLUTATHIONE; REACTIVE OXYGEN METABOLITE;

ACOUSTIC NERVE FIBER; ANIMAL CELL; ARTICLE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; AUDITORY PATHWAYS; BRAIN-DERIVED NEUROTROPHIC FACTOR; BUTHIONINE SULFOXIMINE; CELL SURVIVAL; CISPLATIN; GLUTATHIONE; MICROSCOPY, CONFOCAL; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPIRAL GANGLION;

ANIMALIA;

EID: 0030669432     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00173-3     Document Type: Article

References (39)

1. M. Anniko, A. Sobin, Cisplatin: evaluation of its ototoxic potential, Am. J. Otolaryngol. 7 (1986) 276-293.
2. M.D. Ard, D.K. Morest, S.H. Hauger, Trophic interactions between the cochleovestibular ganglion of the chick embryo and its symtptic targets in culture, Neuroscience 16 (1985) 151-170.
3. H. Asou, E.G. Brunngraber, I. Jeng, Cellular localization of GM1-ganglioside with biotinylated choleragen and avidin peroxidase in primary cultured cells from rat brain, J. Histochem. Cytochem. 31 (1983) 1375-1379.
4. O. Benard, K.A. Balasubramainian, Effect of oxidant exposure on thiol status in the intestinal mucosa, Biochem. Pharmacol. 45 (1993) 2011-2015.
5. R.C. Burghardt, R. Barhoumi, E.H. Lewis, R.H. Bailey, K.A. Pyle, B.A. Clement, T.O. Phillips, Putulin-induced cellular toxicity: a vital flourescent study, Toxicol. Appl. Pharmacol. 112 (1991) 235-244.
6. L. Carenza, C. Villani, M.L. Framarino de Malatesta, R. Prosperi Porta. M. Millefiorine, G. Antonini, P. Bolasco, G. Bandiera, L. Marzetti, Peripheral neuropathy and ototoxicity of dichlorodiamine-platinum: instrumental evaluation, Gynecol. Oncol. 25 (1986) 244-249.
7. W.O. Carter, P.K. Narayanan, J.P. Robinson, Intracellular hydrogen peroxide and Superoxide union detection in endothelial cells, J. Leukocyte Biol. 55 (1994) 53-258.
8. R. Cathcart, E. Schwiers, B.N. Ames, Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay, Anal. Biochem. 134 (1983) 111-116.
9. W.J. Clerici, K. Hensely, D.L. DiMartino, D.A. Butterfield, Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear expiants, Hearing Res. 98 (1996) 116-124.
10. A. Coates, E. Tripp, Comparison of two fluorochromes for flow cytometry assay of cellular glutathione content in human malignant melanoma, Melanoma Res. 5 (1995) 107-111.
11. P. Ernfors, T.R. Van De Water, J. Loring, R. Jaenisch, Complimentary roles of BDNF and NT-3 in veslibular and auditory development. Neuron 14 (1995) 1153-1164.
12. R.W. Fleischman, S.W. Stadnichi, M.F. Ethier, U. Schaeppi, Ototoxicity of cis-dichlorodiammine platinum(II) in the guinea pig, Toxicol. Appl. Pharmacol. 33 (1975) 320-132.
13. R. Gabaizadeh, H. Staecker, W. Liu, R. Kopke, B. Malgarange, P.P. Lefebvre, T.R. Van De Water, Protection of both auditory hair cells and auditory neurons from cisplatin induced damage, Acta Otolaryngol. (Stockh.) 117 (1997) 232-238.
14. V. Galinovic-Schwartz, D. Peng, F.C Chiu, T.R. Van De Water, Temporal pattern of innervation in the developing mouse inner ear: an immunohistochemical study of a 66-kD subunit of mammalian neurofilaments, J. Neurosci. Res. 30 (1991) 124-133.
15. L.J.S. Greenlund, T.L. Deckwerth, E.M. Johnson Jr., Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed cell death. Neuron 14 (1995) 303-315.
16. C.J. Hartnick, H. Staecker, B. Malgrange, P.P. Lefebvre, W. Liu, G. Moonen, T.R. Van De Water, Neurotrophic effects of BDNF and CNTF, alone and in combination, on postnatal day 5 rat acoustic ganglion neurons, J. Neurobiol. 30 (1996) 246-254.
17. J.L. Hegarty, B.J. Gantz, S.H. Green, Factors preventing apoptosis in isolated spiral ganglion neurons, Assoc. Res. Otolaryngol. Mid-winter Meeting, St. Petersburgh, FL, Abstr. 706 (1995).
18. D.W. Huffman, K.L. Jones-King, C.A. Whitworth, L.P. Rybak, Potentiaiton of ototoxicity by glutathione depletion, Ann. Otol. Rhinol. Laryngol. 97 (1988) 36-41.
19. G.R. Jackson, L. Apfel, K. Werrbach-Perez, J.R. Perez Polo, Role of Nerve Growth Factor in oxidant-antioxidant balance and neuronal injury I. Stimulation of hydrogen peroxide resistance. J. Neurosci. Res. 25 (1990) 360-368.
20. G.R. Jackson, K. Werrbach-Perez, J.R. Perez-Polo, Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury II. A conditioning lesion paradigm, J. Neurosci. Res. 25 (1990) 369-374.
21. A. Jain, J. Martensson, E. Stole, P.A. Auld, A. Meister, Glutathione deficiency leads to mitochondrial damage in brain, Proc. Natl. Acad. Sci. USA 88 (1991) 913-1917.
22. R.D. Kopke, W. Liu, R. Gabaizadeh, J. Feghali, D. Spray, H. Steinman, B. Malgrange, R.J. Ruben, L. Ryback, T.R. Van De Water, The use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin induced damage of auditory hair cells, Am. J Otol., (1997) in press.
23. C.P. LeBel, H. Ischiropoulos, S.C. Bondy, Evaluation of the probe 2′,7′ dichlorofluorescin as and indicator of reactive oxygen species formation and oxidative stress, Chem. Res. Toxicol. 5 (1992) 27-231.
24. P.P. Lefebvre, B. Malgrange, H. Staecker, T.R. Van De Water, G. Moonen, Neurotrophins increase survival and neuritogenesis of adult rat auditory neurons in culture, NeuroReport 5 (1994) 865-868.
25. A. Meister, Glutathione deficiency produced by inhibition of its synthesis, and its reversal: applications in research and therapy, Pharmacol. Ther. 51 (1991) 155-194
26. A. Naganuma, M.E. Anderson, A. Meister, Cellular glutathione as a determinant of sensitivity to mercuric chloride toxicity, Biochem. Pharmacol. 40 (1990) 693-697.
27. Z. Pan, R. Perez-Polo, Role of nerve growth factor in oxidant homeostasis glutathione metabolism. J Neurosci. 61 (1993) 1713-1721.
28. M. Poot, T.J. Kavanagh, H.C. Kang, R.P. Haugland, P.S. Rabinovitch, Flow cytometric analysis of cell cycle-dependent changes in cell thiol level by combining a new laser dye with Hoechst 33342, Cytometry 12 (1991) 184-187.
29. R. Ravi, S.M. Somani, L.P. Rybak, Mechanisms of cisplatin ototoxi-city: antioxidant system, Pharmacol. Toxicol. 76 (1995) 386-394.
30. L. Rybak, R. Ravi, S.M. Somani, Mechanism of protection by diethyldithiocarbamate against cisplatin ototoxicity: antioxidant system. Fund. Appl. Toxicol. 26 (1995) 293-300.
31. 2 in cultured endothelial cells, Arch. Biochem. Biophys. 302 (1993) 348-355.
32. D. Sampath, G.R. Jackson, K. Werrbach-Perez, R. Perez-Polo, Effects of nerve growth factor on glutathione peroxidase and catalase in PC12 cells. J. Neurochem. 62 (1994) 2476-2479.
33. M.B. Spina, S.P. Squinto, J. Miller, R.M. Lindsay, C. Hyman, Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and M-methyl-4 phenylpyridinium ion toxicity: involvement of the glutathione system. J. Neurochem. 59 (1992) 99-106.
34. T.R. Van De Water, R.J. Ruben, A possible embryonic mechanism for the establishment of innervation of inner ear sensory structures, Acta Otolaryngol. (Stockh.) 95 (1983) 470-479.
35. S.D. Williams, R. Birch, L.H. Einhorn, L. Irwin, F. Greco, P.J. Loehrer, Treatment of disseminated germ-cell tumors with cisplatin, bleomycin and either vinblastine or etoposide, N. Engl. J. Med. 316 (1987) 1435-1440
36. J. Ylikoski, U. Pirvola, M. Moshnyakov, J. Palgi, U. Arumate, M. Saarma, Expression patterns of neurotrophins and their receptor mRNAs in the rat inner ear, Hearing Res. 65 (1993) 69-78.
37. X.-N. Zhou, T.R. Van De Water, The effect of target tissues on survival and differentiation of mammalian stutoucoustic ganglion neurons in organ culture, Acta Otolaryngol. (Stockh.) 104 (1987) 90-98.
38. J.L. Zheng, R.R. Stewart, W.Q. Gao, Neurotrophin-4/5 enhances survival of cultured spiral ganglion neurons and protects them from cisplatin neurotoxicity, J. Neurosci. 15 (1995) 5079-5087.
39. J.L. Zheng, R.R. Stewart, W.Q. Gao, Neurotrophin-4/5, brain derived neurotrophic factor, and neurotrophin-3 promote survival of cultured vestibulur ganglion neurons and protect them against neurotoxicity of ototoxins, J. Neurobiol. 28 (1995) 330-340.