Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS

Molecular Therapy

Volumn 15, Issue 2, 2007, Pages 242-247

  Liu, Gumei ^a   Chen, Yong Hong ^a   He, Xiaohua ^a   Martins, Inês ^a   Heth, Jason A ^b   Chiorini, John A ^c   Davidson, Beverly L ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; BETA GLUCURONIDASE; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PARVOVIRUS VECTOR; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG EFFICACY; DRUG MECHANISM; GENE EXPRESSION; LEARNING DISORDER; MEMORY DISORDER; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; SPATIAL MEMORY; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BLOTTING, WESTERN; BRAIN; CENTRAL NERVOUS SYSTEM; GENE THERAPY; GENETIC VECTORS; GLUCURONIDASE; HIPPOCAMPUS; LEARNING DISORDERS; MEMORY; MICE; MUCOPOLYSACCHARIDOSIS VII; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE;

ADENO-ASSOCIATED VIRUS; MURINAE; MUS;

EID: 33846312858     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300016     Document Type: Article

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