Improved behavior and neuropathology in the mouse model of sanfilippo type IIIB disease after adeno-associated virus-mediated gene transfer in the striatum

Journal of Neuroscience

Volumn 24, Issue 45, 2004, Pages 10229-10239

  Cressant, Arnaud ^a   Desmaris, Nathalie ^a   Verot, Lucie ^b   Bréjot, Thomas ^a   Froissart, Roseline ^c   Vanier, Marie T ^b   Maire, Irène ^c   Heard, Jean Michel ^a  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c HÔPITAL DEBROUSSE   (France)

Author keywords

N acetylglucosaminidase; Adeno associated virus vectors; Elevated plus maze; Gangliosides; Hyperactivity; Lysosomal storage disease

Indexed keywords

ALPHA N ACETYLGLUCOSAMINIDASE; GANGLIOSIDE GM2; GANGLIOSIDE GM3; HEPARAN SULFATE; LYSOSOME ENZYME; PARVOVIRUS VECTOR;

AGGRESSIVENESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; CELL ORGANELLE; CONTROLLED STUDY; CORPUS STRIATUM; DEVELOPMENTAL DISORDER; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME REPLACEMENT; GENE THERAPY; GENE TRANSFER; HYPERACTIVITY; IMMUNOREACTIVITY; LYSOSOME; MOUSE; NERVE CELL; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUTAMEN; SANFILIPPO SYNDROME; SEROTYPING;

ACETYLGLUCOSAMINIDASE; ANIMALS; BRAIN; CORPUS STRIATUM; DEPENDOVIRUS; EXPLORATORY BEHAVIOR; G(M2) GANGLIOSIDE; G(M3) GANGLIOSIDE; GENE THERAPY; GENETIC VECTORS; INJECTIONS; LYSOSOMES; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSIS III; NEURONS; PUTAMEN;

EID: 8544258806     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3558-04.2004     Document Type: Article

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