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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 9, 2002, Pages 6216-6221

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors

(10) Brooks, Andrew I b Stein, Colleen S a Hughes, Stephanie M a Heth, Jason a McCray Jr , Paul M a Sauter, Sybille L c Johnston, Julie C c Cory Slechta, Deborah A b Federoff, Howard J b Davidson, Beverly L a

a UNIVERSITY OF IOWA (United States)

b UNIVERSITY OF ROCHESTER MEDICAL CENTER (United States)

c NOVARTIS PHARMA AG (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCURONIDASE; VIRUS VECTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; CYTOPATHOLOGY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FELINE IMMUNODEFICIENCY VIRUS; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; INJECTION; LEARNING; LYSOSOME; LYSOSOME STORAGE DISEASE; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASES; COGNITION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLUCURONIDASE; IMMUNODEFICIENCY VIRUS, FELINE; LEARNING; LYSOSOMAL STORAGE DISEASES; MEMORY; MICE; MICE, INBRED C57BL; MODELS, GENETIC; MUCOPOLYSACCHARIDOSIS VII; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMERASE CHAIN REACTION; TRANSGENES;

ANIMALIA; FELIDAE; FELINE IMMUNODEFICIENCY VIRUS; GOES;

EID: 18344368012 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.082011999 Document Type: Article

Times cited : (143)

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