Infectious delivery and expression of a 135kb human FRDA genomic DNA locus complements friedreich's ataxia deficiency in human cells

Molecular Therapy

Volumn 15, Issue 2, 2007, Pages 248-254

  Gomez Sebastian, Silvia ^a   Gimenez Cassina, Alfredo ^b   Diaz Nido, Javier ^b   Lim, Filip ^b   Wade Martins, Richard ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; GENOMIC DNA; HERPESVIRUS VECTOR;

AMPLICON; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; DNA FLANKING REGION; DRUG MECHANISM; FIBROBLAST; FRIEDREICH ATAXIA; GENE EXPRESSION; GENE LOCUS; GENETIC COMPLEMENTATION; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; INTRON; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHENOTYPE; PROMOTER REGION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WILD TYPE;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; FIBROBLASTS; FRIEDREICH ATAXIA; GENE THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; IRON-BINDING PROTEINS; MICE; MODELS, GENETIC; MOLECULAR WEIGHT; OXIDATIVE STRESS;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 1;

EID: 33846308499     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300021     Document Type: Article

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