Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice

Archives of Toxicology

Volumn 81, Issue 1, 2007, Pages 63-69

  Kuroiwa, Yuichi ^a   Umemura, Takashi ^a   Nishikawa, Akiyoshi ^a   Kanki, Keita ^a   Ishii, Yuji ^a   Kodama, Yukio ^a   Masumura, Ken Ichi ^a   Nohmi, Takehiko ^a   Hirose, Masao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Cell proliferation; Flumequine; gpt delta mouse; In vivo mutagenicity; Oxidative DNA damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALANINE AMINOTRANSFERASE; BROXURIDINE; FLUMEQUINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL VACUOLE; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENE DELETION; GENE MUTATION; HISTOPATHOLOGY; LIVER; LIVER INJURY; MALE; MOUSE; MOUSE STRAIN; MUTAGENICITY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTI-INFECTIVE AGENTS; BROMODEOXYURIDINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA DAMAGE; EATING; ESCHERICHIA COLI PROTEINS; FEMALE; FLUOROQUINOLONES; HEPATOCYTES; IMMUNOCHEMISTRY; LIVER; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTATION; ORGAN SIZE; PENTOSYLTRANSFERASES; WEIGHT LOSS;

BACTERIA (MICROORGANISMS); MUS;

EID: 33846299897     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0126-9     Document Type: Article

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