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Volumn 42, Issue 1, 2005, Pages 9-17

In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3- methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate

Author keywords

gpt delta rats; Hepatocarcinogens; In vivo mutation assay

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; CARCINOGEN; DNA; GLUTATHIONE S TRANSFERASE PLACENTAL FORM; GLUTATHIONE TRANSFERASE; N NITROSOPYRROLIDINE; PARACETAMOL; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; UNCLASSIFIED DRUG;

EID: 11144322896     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.20061     Document Type: Article
Times cited : (49)

References (50)
  • 1
    • 0023072988 scopus 로고
    • Carcinogenicity and mutagenicity of N-nitroso compounds
    • Lijinsky W. Carcinogenicity and mutagenicity of N-nitroso compounds. Mol Toxicol 1987;1:107-119.
    • (1987) Mol Toxicol , vol.1 , pp. 107-119
    • Lijinsky, W.1
  • 2
    • 0026317526 scopus 로고
    • Evidence that toxic injury is not always associated with induction of chemical carcinogenesis
    • Tennant RW, Elwell MR, Spalding JW, Griesemer RA. Evidence that toxic injury is not always associated with induction of chemical carcinogenesis. MoI Carcinog 1991;4: 420-440.
    • (1991) MoI Carcinog , vol.4 , pp. 420-440
    • Tennant, R.W.1    Elwell, M.R.2    Spalding, J.W.3    Griesemer, R.A.4
  • 4
    • 0032774222 scopus 로고    scopus 로고
    • Comparative in vitro and in vivo assessment of genotoxic effects of etoposide and chlorothalonil by the comet assay
    • Godard T, Fessard V, Huet S, et al. Comparative in vitro and in vivo assessment of genotoxic effects of etoposide and chlorothalonil by the comet assay. Mutat Res 1999;444: 103-116.
    • (1999) Mutat Res , vol.444 , pp. 103-116
    • Godard, T.1    Fessard, V.2    Huet, S.3
  • 5
    • 0034693862 scopus 로고    scopus 로고
    • Recent advances in the protocols of transgenic mouse mutation assays
    • Nohmi T, Suzuki T, Masumura K. Recent advances in the protocols of transgenic mouse mutation assays. Mutat Res 2000;455:191-215.
    • (2000) Mutat Res , vol.455 , pp. 191-215
    • Nohmi, T.1    Suzuki, T.2    Masumura, K.3
  • 8
    • 0017112238 scopus 로고
    • The effect of substituents on the carcinogenicity of N-nitrosopyrrolidine in Sprague-Dawley Rats
    • Lijinsky W, Taylor HW. The effect of substituents on the carcinogenicity of N-nitrosopyrrolidine in Sprague-Dawley Rats. Cancer Res 1976;36:1988-1990.
    • (1976) Cancer Res , vol.36 , pp. 1988-1990
    • Lijinsky, W.1    Taylor, H.W.2
  • 9
    • 33746530663 scopus 로고
    • Evaluation of the carcinogenic risk of chemicals to humans: Some N-nitroso compounds
    • Bartsch H, O'Neill IK, Castegnaro M, Okada M. Evaluation of the carcinogenic risk of chemicals to humans: Some N-nitroso compounds. IARC Sci Publ 1978;39:313-326.
    • (1978) IARC Sci Publ , vol.39 , pp. 313-326
    • Bartsch, H.1    O'Neill, I.K.2    Castegnaro, M.3    Okada, M.4
  • 10
    • 0034770816 scopus 로고    scopus 로고
    • Reactions of alpha-acetoxy-N-nitrosopyrrolidine with deoxyguanosine and DNA
    • Wang M, MacIntee EJ, Shi Y, et al. Reactions of alpha-acetoxy-N- nitrosopyrrolidine with deoxyguanosine and DNA. Chem Res Toxicol 2001;14:1435-1445.
    • (2001) Chem Res Toxicol , vol.14 , pp. 1435-1445
    • Wang, M.1    MacIntee, E.J.2    Shi, Y.3
  • 11
    • 0023263169 scopus 로고
    • N-nitrosamines: Bacterial mutagenesis and in vitro metabolism
    • Guttenplan JB. N-nitrosamines: Bacterial mutagenesis and in vitro metabolism. Mutat Res 1987;186:81-134.
    • (1987) Mutat Res , vol.186 , pp. 81-134
    • Guttenplan, J.B.1
  • 12
    • 0025329099 scopus 로고
    • Mutational specificities of environmental carcinogens in the lacl gene of Escherichia coli. III: The cyclic nitrosamine N-nitrosopyrrolidine is a complex mutagen
    • Ziellenska M, Ahmed A, Glickman BW. Mutational specificities of environmental carcinogens in the lacl gene of Escherichia coli. III: The cyclic nitrosamine N-nitrosopyrrolidine is a complex mutagen. Mol Carcinog 1990;3:122-125.
    • (1990) Mol Carcinog , vol.3 , pp. 122-125
    • Ziellenska, M.1    Ahmed, A.2    Glickman, B.W.3
  • 13
    • 0033645710 scopus 로고    scopus 로고
    • Oxidative damage and induced mutations in m13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation
    • Arimoto KS, Anma N, Yoshinaga Y, Douki T, Cadet J, Hayatsu H. Oxidative damage and induced mutations in m13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation. Mutagenesis 2000;15:473-477.
    • (2000) Mutagenesis , vol.15 , pp. 473-477
    • Arimoto, K.S.1    Anma, N.2    Yoshinaga, Y.3    Douki, T.4    Cadet, J.5    Hayatsu, H.6
  • 15
    • 0018141578 scopus 로고
    • Carcinogenicity of N-nitroso compounds and their possible role in the development of human cancer
    • Griciute L. Carcinogenicity of N-nitroso compounds and their possible role in the development of human cancer. IARC Sci Publ 1978;18:3-9.
    • (1978) IARC Sci Publ , vol.18 , pp. 3-9
    • Griciute, L.1
  • 16
    • 0022506196 scopus 로고
    • Detection of 2-amino-3-methylimidazo[4,5-f]quinoline in cigarette smoke condensate
    • Yamashita M, Wakabayashi K, Nagao M, et al. Detection of 2-amino-3-methylimidazo[4,5-f]quinoline in cigarette smoke condensate. Jpn J Cancer Res (Gann) 1986;77:419-422.
    • (1986) Jpn J Cancer Res (Gann) , vol.77 , pp. 419-422
    • Yamashita, M.1    Wakabayashi, K.2    Nagao, M.3
  • 17
    • 0022556813 scopus 로고
    • Carcinogenicity in mice and rats of heterocyclic amines in cooked foods
    • Ohgaki H, Hasegawa H, Kato T, et al. Carcinogenicity in mice and rats of heterocyclic amines in cooked foods. Environ Health Perspect 1986;67:129-134.
    • (1986) Environ Health Perspect , vol.67 , pp. 129-134
    • Ohgaki, H.1    Hasegawa, H.2    Kato, T.3
  • 18
    • 0025037603 scopus 로고
    • Carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in non-human primates: Induction of tumors in three macaques
    • Adamson RH, Thorgeirsson UP, Snyderwine EG, et al. Carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in non-human primates: Induction of tumors in three macaques. Jpn J Cancer Res 1990;81:10-14.
    • (1990) Jpn J Cancer Res , vol.81 , pp. 10-14
    • Adamson, R.H.1    Thorgeirsson, U.P.2    Snyderwine, E.G.3
  • 19
    • 0033034183 scopus 로고    scopus 로고
    • DNA adducts of heterocyclic amine food mutagens: Implications for mutagenesis and carcinogenesis
    • Schut HAJ, Snyderwine EG. DNA adducts of heterocyclic amine food mutagens: Implications for mutagenesis and carcinogenesis. Carcinogenesis 1999;20:353-368.
    • (1999) Carcinogenesis , vol.20 , pp. 353-368
    • Schut, H.A.J.1    Snyderwine, E.G.2
  • 20
    • 0033977633 scopus 로고    scopus 로고
    • Mutational analysis of the liver, colon, and kidney of BigBlue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline
    • Bol SA, Horlbeck J, Markovic J, de Boer JG, Turesky RJ, Constable A. Mutational analysis of the liver, colon, and kidney of BigBlue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline. Carcinogenesis 2000;21:1-6.
    • (2000) Carcinogenesis , vol.21 , pp. 1-6
    • Bol, S.A.1    Horlbeck, J.2    Markovic, J.3    De Boer, J.G.4    Turesky, R.J.5    Constable, A.6
  • 21
    • 0020334761 scopus 로고
    • Carcinogenicity testing of phthalate esters and related compounds by the National Toxicology Program and the National Cancer Institute
    • Kluwe WM, McConnell EE, Huff JE, Haseman JK, Douglas JF, Hartwell WV. Carcinogenicity testing of phthalate esters and related compounds by the National Toxicology Program and the National Cancer Institute. Environ Health Perspect 1982; 45:129-133.
    • (1982) Environ Health Perspect , vol.45 , pp. 129-133
    • Kluwe, W.M.1    McConnell, E.E.2    Huff, J.E.3    Haseman, J.K.4    Douglas, J.F.5    Hartwell, W.V.6
  • 22
    • 0021091385 scopus 로고
    • Evaluation of di-(2-ethylhexyl)phthalate and its major metabolites in the Ames test and L5178Y mouse lymphoma mutagenicity assay
    • Kirby PE, Pizzarello RF, Lawlor TE, Haworth SR, Hodgson JR. Evaluation of di-(2-ethylhexyl)phthalate and its major metabolites in the Ames test and L5178Y mouse lymphoma mutagenicity assay. Environ Mutagen 1983;5: 657-663.
    • (1983) Environ Mutagen , vol.5 , pp. 657-663
    • Kirby, P.E.1    Pizzarello, R.F.2    Lawlor, T.E.3    Haworth, S.R.4    Hodgson, J.R.5
  • 23
    • 0022390108 scopus 로고
    • Mutagenicity testing of di(2-ethylhexyl)phthalate and related chemicals in Salmonella
    • Zeiger E, Haworth S, Mortelmans K, Speck W. Mutagenicity testing of di(2-ethylhexyl)phthalate and related chemicals in Salmonella. Environ Mutagen 1985;7:213-232.
    • (1985) Environ Mutagen , vol.7 , pp. 213-232
    • Zeiger, E.1    Haworth, S.2    Mortelmans, K.3    Speck, W.4
  • 24
    • 0017107292 scopus 로고
    • Teratogenicity and mutagenicity of a phthalate ester
    • Yagi YK, Shimoi N. Teratogenicity and mutagenicity of a phthalate ester. Teratology 1976;14:259-260.
    • (1976) Teratology , vol.14 , pp. 259-260
    • Yagi, Y.K.1    Shimoi, N.2
  • 26
    • 0025259590 scopus 로고
    • Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di-(2-ethylhexyl)phthalate and di-(2-ethylhexyl)adipate
    • Takagi A, Sai K, Umemura T, Hasegawa R, Kurokawa Y. Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di-(2-ethylhexyl)phthalate and di-(2-ethylhexyl)adipate. Jpn J Cancer Res 1990;81:213-215.
    • (1990) Jpn J Cancer Res , vol.81 , pp. 213-215
    • Takagi, A.1    Sai, K.2    Umemura, T.3    Hasegawa, R.4    Kurokawa, Y.5
  • 27
    • 0242494348 scopus 로고    scopus 로고
    • Comparison of oxidative stress and changes of xonobiotic metabolizing enzymes induced by phthalates in rats
    • Seo KW, Kim KB, Kim YJ, Choi JY, Lee KT, Choi KS. Comparison of oxidative stress and changes of xonobiotic metabolizing enzymes induced by phthalates in rats. Food Chem Toxicol 2004;42:107-114.
    • (2004) Food Chem Toxicol , vol.42 , pp. 107-114
    • Seo, K.W.1    Kim, K.B.2    Kim, Y.J.3    Choi, J.Y.4    Lee, K.T.5    Choi, K.S.6
  • 28
    • 0029061266 scopus 로고
    • Overview of mutation assays in transgenic mice for routine testing
    • Gorelick NJ. Overview of mutation assays in transgenic mice for routine testing. Environ Mol Mutagen 1995;25: 218-230.
    • (1995) Environ Mol Mutagen , vol.25 , pp. 218-230
    • Gorelick, N.J.1
  • 30
    • 0035169076 scopus 로고    scopus 로고
    • Protection by dietary compounds against mutation in a transgenic rodent
    • de Boer JG. Protection by dietary compounds against mutation in a transgenic rodent. J Nutr 2001;131:3082S-3086S.
    • (2001) J Nutr , vol.131
    • De Boer, J.G.1
  • 31
    • 0035025269 scopus 로고    scopus 로고
    • Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis
    • Nishikawa A, Suzuki T, Masumura K, et al. Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis. J Exp Clin Cancer Res 2001;20:111-115.
    • (2001) J Exp Clin Cancer Res , vol.20 , pp. 111-115
    • Nishikawa, A.1    Suzuki, T.2    Masumura, K.3
  • 32
    • 15444351785 scopus 로고    scopus 로고
    • Medium-term rat liver bioassay for rapid detection of hepatocarcinogenic substances
    • Ito N, Hasegawa R, Imaida K, et al. Medium-term rat liver bioassay for rapid detection of hepatocarcinogenic substances. J Toxicol Pathol 1997;10:1-11.
    • (1997) J Toxicol Pathol , vol.10 , pp. 1-11
    • Ito, N.1    Hasegawa, R.2    Imaida, K.3
  • 33
    • 0026683481 scopus 로고
    • Hepatomegaly is an early biomarker for hepatocarcinogenesis induced by peroxisome proliferators
    • Takagi A, Sai K, Umemura T, Hasegawa R, Kurokawa Y. Hepatomegaly is an early biomarker for hepatocarcinogenesis induced by peroxisome proliferators. J Environ Pathol Toxicol Oncol 1992;11:145-149.
    • (1992) J Environ Pathol Toxicol Oncol , vol.11 , pp. 145-149
    • Takagi, A.1    Sai, K.2    Umemura, T.3    Hasegawa, R.4    Kurokawa, Y.5
  • 34
    • 0028556580 scopus 로고
    • Tissue-specific mutational spectra of 2-amino-3,4-dimethylimidazo[4,5-f] quinoline in the liver and bone marrow of lacl transgenic mice
    • Ushijima T, Hosoya Y, Ochiai M, et al. Tissue-specific mutational spectra of 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in the liver and bone marrow of lacl transgenic mice. Carcinogenesis 1994;15:2805-2809.
    • (1994) Carcinogenesis , vol.15 , pp. 2805-2809
    • Ushijima, T.1    Hosoya, Y.2    Ochiai, M.3
  • 35
    • 0030599151 scopus 로고    scopus 로고
    • In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice
    • Davis CD, Dacquel HAJ, Schut SS, Thorgeirsson SS, Snyderwine EG. In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice. Mutat Res 1996;356:287-296.
    • (1996) Mutat Res , vol.356 , pp. 287-296
    • Davis, C.D.1    Dacquel, H.A.J.2    Schut, S.S.3    Thorgeirsson, S.S.4    Snyderwine, E.G.5
  • 36
    • 0029875810 scopus 로고    scopus 로고
    • DNA adduct formation of the food-derived mutagen 2-amino-3,4- dimethylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay
    • Turesky RJ, Gremaud E, Markovic J, Snyderwine EG. DNA adduct formation of the food-derived mutagen 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay. Chem Res Toxicol 1996;9: 403-408.
    • (1996) Chem Res Toxicol , vol.9 , pp. 403-408
    • Turesky, R.J.1    Gremaud, E.2    Markovic, J.3    Snyderwine, E.G.4
  • 37
    • 0033564662 scopus 로고    scopus 로고
    • Nonenzymatic reduction of nitro derivative of a heterocyclic amine IQ by NADH and Cu(II) leads to oxidative DNA damage
    • Murata M, Kobayashi M, Kawanishi S. Nonenzymatic reduction of nitro derivative of a heterocyclic amine IQ by NADH and Cu(II) leads to oxidative DNA damage. Biochemistry 1999;38:7624-7629.
    • (1999) Biochemistry , vol.38 , pp. 7624-7629
    • Murata, M.1    Kobayashi, M.2    Kawanishi, S.3
  • 38
    • 18144442577 scopus 로고    scopus 로고
    • Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of BigBlue rats: Role of DNA adducts, strand breaks, DNA repair, and oxidative stress
    • Moller P, Wallin H, Vogel U, et al. Mutagenicity of 2-amino-3- methylimidazo[4,5-f]quinoline in colon and liver of BigBlue rats: Role of DNA adducts, strand breaks, DNA repair, and oxidative stress. Carcinogenesis 2002;23:1379-1385.
    • (2002) Carcinogenesis , vol.23 , pp. 1379-1385
    • Moller, P.1    Wallin, H.2    Vogel, U.3
  • 39
    • 0027468463 scopus 로고
    • Can nongenotoxic carcinogens be detected with the lacl transgenic mouse mutation assay?
    • Gunz D, Shephard SE, Lutz WK. Can nongenotoxic carcinogens be detected with the lacl transgenic mouse mutation assay? Environ Mol Mutagen 1993;21:209-211.
    • (1993) Environ Mol Mutagen , vol.21 , pp. 209-211
    • Gunz, D.1    Shephard, S.E.2    Lutz, W.K.3
  • 40
    • 0027399969 scopus 로고
    • Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G:C-T:A transversions in simian kidney cells
    • Moriya M. Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G:C-T:A transversions in simian kidney cells. Proc Natl Acad Sci USA 1993;90:1122-1126.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1122-1126
    • Moriya, M.1
  • 41
    • 0023925366 scopus 로고
    • Identification of crotonaldehyde as a hepatic microsomal metabolite formed by alpha-hydroxylation of the carcinogen N-nitrosopyrrolidine
    • Wang M, Chung FL, Hecht SS. Identification of crotonaldehyde as a hepatic microsomal metabolite formed by alpha-hydroxylation of the carcinogen N-nitrosopyrrolidine. Chem Res Toxicol 1988;1:28-31.
    • (1988) Chem Res Toxicol , vol.1 , pp. 28-31
    • Wang, M.1    Chung, F.L.2    Hecht, S.S.3
  • 42
    • 0024797864 scopus 로고
    • Formation of acyclic and cyclic guanine adducts in DNA reacted with α-acetoxy-N-nitroso-pyrrolidine
    • Wang M, Chung FL, Hecht SS. Formation of acyclic and cyclic guanine adducts in DNA reacted with α-acetoxy-N-nitroso-pyrrolidine. Chem Res Toxicol 1989;2:423-428.
    • (1989) Chem Res Toxicol , vol.2 , pp. 423-428
    • Wang, M.1    Chung, F.L.2    Hecht, S.S.3
  • 43
    • 0025904427 scopus 로고
    • Formation and persistence of a DNA adduct in rodents treated with N-nitrosopyrrolidine
    • Hunt EJ, Shank RC. Formation and persistence of a DNA adduct in rodents treated with N-nitrosopyrrolidine. Carcinogenesis 1991;12:571-575.
    • (1991) Carcinogenesis , vol.12 , pp. 571-575
    • Hunt, E.J.1    Shank, R.C.2
  • 44
    • 0024389936 scopus 로고
    • 2-propanodeoxyguanosine adducts in DNA of rats treated with N-nitrosopyrrolidine and mice treated with crotonaldehyde
    • 2- propanodeoxyguanosine adducts in DNA of rats treated with N-nitrosopyrrolidine and mice treated with crotonaldehyde. Carcinogenesis 1989;10:1291-1297.
    • (1989) Carcinogenesis , vol.10 , pp. 1291-1297
    • Chung, F.L.1    Young, R.2    Hecht, S.S.3
  • 45
    • 0028117699 scopus 로고
    • Formation of etheno adducts in reactions of enals via autoxidation
    • Chen HJ, Chung FL. Formation of etheno adducts in reactions of enals via autoxidation. Chem Res Toxicol 1994; 7:857-860.
    • (1994) Chem Res Toxicol , vol.7 , pp. 857-860
    • Chen, H.J.1    Chung, F.L.2
  • 47
    • 0029741323 scopus 로고    scopus 로고
    • Formation and accumulation of DNA ethenobases in adult Sprague-Dawley rats exposed to vinyl chloride
    • Guichard Y, el Ghissassi F, Nair J, Bartsch H, Barbin A. Formation and accumulation of DNA ethenobases in adult Sprague-Dawley rats exposed to vinyl chloride. Carcinogenesis 1996;17:1553-1559.
    • (1996) Carcinogenesis , vol.17 , pp. 1553-1559
    • Guichard, Y.1    El Ghissassi, F.2    Nair, J.3    Bartsch, H.4    Barbin, A.5
  • 48
    • 0035500819 scopus 로고    scopus 로고
    • Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on administration via the portal vein
    • Satoh K, Hayakari M, Ookawa K, et al. Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on administration via the portal vein. Mutat Res 2001;483: 65-72.
    • (2001) Mutat Res , vol.483 , pp. 65-72
    • Satoh, K.1    Hayakari, M.2    Ookawa, K.3
  • 49
    • 0029665327 scopus 로고    scopus 로고
    • 6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells
    • 6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells. Biochemistry 1996;35:11487-11492.
    • (1996) Biochemistry , vol.35 , pp. 11487-11492
    • Pandya, G.A.1    Moriya, M.2
  • 50
    • 0030916130 scopus 로고    scopus 로고
    • p53 gene mutation pattern in rat liver tumor induced by vinyl chloride
    • Barbin A, Froment O, Boibin S, et al. p53 Gene mutation pattern in rat liver tumor induced by vinyl chloride. Cancer Res 1997;57:1695-1698.
    • (1997) Cancer Res , vol.57 , pp. 1695-1698
    • Barbin, A.1    Froment, O.2    Boibin, S.3


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