Synthesis and antiparasitic activity against Trypanosoma cruzi and Leishmania amazonensis of chlorinated 1,7- and 1,8-naphthyridines

Letters in Drug Design and Discovery

Volumn 4, Issue 2, 2007, Pages 154-159

  Da Silva, Luiz Everson ^a,d   Joussef, Antônio Carlos ^a   Pacheco, Letícia Kramer ^b   Albino, Danielle Bibas Legat ^b   Duarte, Anita Maurício Camilo ^b   Steindel, Mário ^b   Rebelo, Ricardo Andrade ^c  

^a Campus Trindade   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c Campus I   (Brazil)

^d FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

Antiparasitic; Chloronaphthyridines; Trypanocidal and leishmanicidal activities

Indexed keywords

2,2 DIMETHYL 5 [[(2,6 DICHLORO 3 PYRIDYL)AMINO]METHYLENE] 1,3 DIOXANE 4,6 DIONE; 2,6 BIS [(2,2 DIMETHYL 4,6 DIOXO 1,3 DIOXANE 5 YLIDENEMETHYL)AMINO]PYRIDINE; 4,10 DIOXO 1H PYRIMIDO[1,2 A]NAPHTHYRIDINE; 4,5,6,8,9 PENTACHLORO 10 OXO PYRIMIDO[1,2 A]1,8 NAPHTHYRIDINE; 4,6,8 TRICHLORO[1,7]NAPHTHYRIDINE; 5 [(4,6 DIMETHYLPYRIDIN 2 YLAMINO)METHYLENE] 2,2 DIMETHYL[1,3]DIOXANE 4,6 DIONE; 5 CHLORO 2,4 DIMETHYL 1,8 NAPHTHYRIDINE; 5,7 DIMETHYL[1H]NAPHTHYRIDIN 4 ONE; 6,8 DICHLORO[1,7]NAPHTHYRIDIN 4 (1H) ONE; AMPHOTERICIN B; BENZNIDAZOLE; CHLORINATED 1,7 NAPHTHYRIDINE DERIVATIVE; CHLORINATED 1,8 NAPHTHYRIDINE DERIVATIVE; NAPHTHYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; EPIMASTIGOTE; IC 50; LEISHMANIA; NONHUMAN; PARASITE CULTIVATION; PRIORITY JOURNAL; PROMASTIGOTE; TRYPANOSOMA CRUZI; VERO CELL;

EID: 33846287884     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018007779422550     Document Type: Article

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