Synthesis and antileishmanial activity of (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives

European Journal of Medicinal Chemistry

Volumn 39, Issue 8, 2004, Pages 685-690

  Delmas, Florence ^a   Avellaneda, Antonio ^a   Di Giorgio, Carole ^a   Robin, Maxime ^a   De Clercq, Erik ^b   Timon David, Pierre ^a   Galy, Jean Pierre ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Acridinones; Anti amastigote activity; Antileishmanial activity

Indexed keywords

1 (6 AMINOBENZOTHIAZOL 2 YLAMINO) 10H ACRIDIN 9 ONE; 4 (6 NITROBENZOTHIAZOL 2 YLAMINO) 10H ACRIDIN 9 ONE; 6 AMINOBENZOTHIAZOLE; 6 NITROBENZOTHIAZOLE; ACRIDINE DERIVATIVE; AMINO 9(10H) ACRIDINONE; AMINO ACID; ANTILEISHMANIAL AGENT; BENZOTHIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANTIPROTOZOAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; SYNTHESIS;

EID: 3242778619     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.04.006     Document Type: Article

References (21)

1. Alberti P., Ren J., Teulade-Fichou M.P., Guittat L., Riou J.F., Chaires J., Helene C., Vigneron J.P., Lehn J.M., Mergny J.L. J. Biomol. Struct. Dyn. 19:2001;505-513
2. Ferguson L.R., Denny W.A. Mutat. Res. 258:1991;123-160
3. Wainwright M. J. Antimicrob. Chemother. 47:2001;1-13
4. Demeunynck M., Charmantray F., Martelli A. Curr. Pharm. Des. 7:2001;1703-1724
5. Antonini I., Polucci P., Magnano A., Sante M. J. Med. Chem. 56:2001;3329-3333
6. Girault S., Grellier P., Berecibar A., Maes L., Mouray E., Lemiere P., Debreu M.A., Davioud-Charvet E., Sergheraert C. J. Med. Chem. 43:2000;2646-2654
7. Girault S., Delarue S., Grellier P., Berecibar A., Maes L., Quirijnen L., Lemiere P., Debreu-Fontaine M.A., Sergheraert C. J. Pharm. Pharmacol. 53:2001;935-938
8. Gamage S.A., Figgit D.P., Wojcik S.J., Ralph R.K., Ransijn A., Mauel J., Yardley V., Snowdon D., Croft S.L., Denny W. J. Med. Chem. 40:1997;2634-2642
9. Werbovetz K.A., Spoors P.G., Pearson R.D., Macdonald T.L. Mol. Biochem. Parasitol. 65:1994;1-10
10. Mesa-Valle C.M., Castilla-Calvente J., Sanchez-Moreno M., Moraleda-Lindez V., Barbe J., Osuna A. Antimicrob. Agents Chemother. 40:1996;684-690
11. Lowden C.T., Bastow K.F. Antiviral Res. 59:2003;143-154
12. Di Giorgio C., Delmas F., Filloux N., Robin M., Seferian L., Azas N., Gasquet M., Timon-David P., Galy J.P. Antimicrob. Agents Chemother. 47:2003;174-180
13. Delmas F., Di Giorgio C., Robin M., Azas N., Gasquet M., Detang C., Costa M., Timon-David P., Galy J.P. Antimicrob. Agents Chemother. 46:2002;2588-2594
14. Bsiri N., Johnson C., Kayirere M., Galy A.M., Galy J.P., Barbe J., Osuna A., Mesa-Valle M.C., Castilla-Calvente J.J., Rodriguez-Cabezas M.N. Ann. Pharm. 54:1996;27-33
15. Hanoun J.P., Galy J.P., Tenaglia A. Synth. Commun. 25:1995;2443-2448
16. Katz L. J. Chem. Soc. 75:1953;712-714
17. Bouchet P., Coquelet C., Joncheray G., Elguero J. Synth. Commun. 4:1974;57
18. Avellaneda A., Robin M., Faure R., Périchaud A., Galy J.P. Magn. Reson. Chem. 40:2002;545-548
19. Ogunkolade B.W., Colomb-Valet I., Monjour L., Rhodes-Feuillette A., Abita J.P., Frommel D. Acta Trop. 47:1990;171-176
20. Popovic M., Sarngadharan M.G., Read E., Gallo R.C. Science. 224:1984;497
21. Pauwels R., Balzarini J., Baba M., Snoeck R., Schols D., Pherdewijn J., Desmyter J., De Clercq E. J. Virol. Methods. 20:1988;309