The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity

EMBO Journal

Volumn 26, Issue 1, 2007, Pages 90-101

  Poyurovsky, Masha V ^a   Priest, Christina ^a   Kentsis, Alex ^b   Borden, Katherine L B ^b   Pan, Zhen Qiang ^b   Pavletich, Nikola ^c   Prives, Carol ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

E3; Mdm2; Oligomerization; p53; Ubiquitin

Indexed keywords

AMINO ACID; OLIGOMER; PHENYLALANINE; PROTEIN MDM2; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; ELECTRON MICROSCOPY; ENZYME ACTIVITY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SUPRAMOLECULAR CHEMISTRY;

ADENOSINE TRIPHOSPHATE; CELL LINE, TUMOR; ESCHERICHIA COLI; HUMANS; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 33846239416     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601465     Document Type: Article

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