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Volumn 5, Issue 12, 2006, Pages 3153-3161

Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXYMETHYLACYLFULVENE; ATM PROTEIN; ATR PROTEIN; DOUBLE STRANDED DNA; FANCONI ANEMIA GROUP D2 PROTEIN;

EID: 33846211831     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0427     Document Type: Article
Times cited : (20)

References (59)
  • 1
    • 1942502234 scopus 로고    scopus 로고
    • Tracing the network connecting BRCA and Fanconi anaemia proteins
    • Venkitaraman AR. Tracing the network connecting BRCA and Fanconi anaemia proteins. Nat Rev Cancer 2004;4:266-76.
    • (2004) Nat Rev Cancer , vol.4 , pp. 266-276
    • Venkitaraman, A.R.1
  • 2
    • 0037268338 scopus 로고    scopus 로고
    • The Fanconi anaemia/BRCA pathway
    • D'Andrea AD, Grompe M. The Fanconi anaemia/BRCA pathway. Nat Rev Cancer 2003;3:23-34.
    • (2003) Nat Rev Cancer , vol.3 , pp. 23-34
    • D'Andrea, A.D.1    Grompe, M.2
  • 3
    • 17744394476 scopus 로고    scopus 로고
    • Positional cloning of a novel Fanconi anemia gene, FANCD2
    • Timmers C, Taniguchi T, Hejna J, et al. Positional cloning of a novel Fanconi anemia gene, FANCD2. Mol Cell 2001;7:241-8.
    • (2001) Mol Cell , vol.7 , pp. 241-248
    • Timmers, C.1    Taniguchi, T.2    Hejna, J.3
  • 4
    • 0035105291 scopus 로고    scopus 로고
    • Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
    • Garcia-Higuera I, Taniguchi T, Ganesan S, et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 2001;7:249-62.
    • (2001) Mol Cell , vol.7 , pp. 249-262
    • Garcia-Higuera, I.1    Taniguchi, T.2    Ganesan, S.3
  • 5
    • 2942664480 scopus 로고    scopus 로고
    • FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination
    • Meetei AR, Yen Z, Wang W. FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination. Cell Cycle 2004;3:179-81.
    • (2004) Cell Cycle , vol.3 , pp. 179-181
    • Meetei, A.R.1    Yen, Z.2    Wang, W.3
  • 6
    • 25144492769 scopus 로고    scopus 로고
    • Unraveling the Fanconi anemia-DNA repair connection
    • Thompson LH. Unraveling the Fanconi anemia-DNA repair connection. Nat Genet 2005;37:921-2.
    • (2005) Nat Genet , vol.37 , pp. 921-922
    • Thompson, L.H.1
  • 7
    • 26944499485 scopus 로고    scopus 로고
    • The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway
    • Mosedale G, Niedzwiedz W, Alpi A, et al. The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nat Struct Mol Biol 2005;12:763-71.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 763-771
    • Mosedale, G.1    Niedzwiedz, W.2    Alpi, A.3
  • 8
    • 24944575242 scopus 로고    scopus 로고
    • BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ
    • Litman R, Peng M, Jin Z, et al. BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ. Cancer Cell 2005;8:255-65.
    • (2005) Cancer Cell , vol.8 , pp. 255-265
    • Litman, R.1    Peng, M.2    Jin, Z.3
  • 9
    • 0035864856 scopus 로고    scopus 로고
    • Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway
    • Medhurst AL, Huber PA, Waisfisz Q, de Winter JP, Mathew CG. Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. Hum Mol Genet 2001;10:423-9.
    • (2001) Hum Mol Genet , vol.10 , pp. 423-429
    • Medhurst, A.L.1    Huber, P.A.2    Waisfisz, Q.3    de Winter, J.P.4    Mathew, C.G.5
  • 10
    • 0038642027 scopus 로고    scopus 로고
    • A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome
    • Meetei AR, Sechi S, Wallisch M, et al. A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol Cell Biol 2003;23: 3417-26.
    • (2003) Mol Cell Biol , vol.23 , pp. 3417-3426
    • Meetei, A.R.1    Sechi, S.2    Wallisch, M.3
  • 11
    • 0141484612 scopus 로고    scopus 로고
    • A novel ubiquitin ligase is deficient in Fanconi anemia
    • Meetei AR, de Winter JP, Medhurst AL, et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 2003;35:165-70.
    • (2003) Nat Genet , vol.35 , pp. 165-170
    • Meetei, A.R.1    de Winter, J.P.2    Medhurst, A.L.3
  • 12
    • 10944239213 scopus 로고    scopus 로고
    • X-linked inheritance of Fanconi anemia complementation group B
    • Meetei AR, Levitus M, Xue Y, et al. X-linked inheritance of Fanconi anemia complementation group B. Nat Genet 2004;36:1219-24.
    • (2004) Nat Genet , vol.36 , pp. 1219-1224
    • Meetei, A.R.1    Levitus, M.2    Xue, Y.3
  • 13
    • 25144449181 scopus 로고    scopus 로고
    • A human orthologi of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
    • Meetei AR, Medhurst AL, Ling C, et al. A human orthologi of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet 2005;37:958-63.
    • (2005) Nat Genet , vol.37 , pp. 958-963
    • Meetei, A.R.1    Medhurst, A.L.2    Ling, C.3
  • 14
    • 13244291457 scopus 로고    scopus 로고
    • The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
    • Nijman SM, Huang TT, Dirac AM, et al. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell 2005;17:331-9.
    • (2005) Mol Cell , vol.17 , pp. 331-339
    • Nijman, S.M.1    Huang, T.T.2    Dirac, A.M.3
  • 15
    • 18444362122 scopus 로고    scopus 로고
    • Biallelic inactivation of BRCA2 in Fanconi anemia
    • Howlett NG, Taniguchi T, Olson S, et al. Biallelic inactivation of BRCA2 in Fanconi anemia. Science 2002;297:606-9.
    • (2002) Science , vol.297 , pp. 606-609
    • Howlett, N.G.1    Taniguchi, T.2    Olson, S.3
  • 16
    • 2942705849 scopus 로고    scopus 로고
    • Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
    • Wang X, Andreassen PR, D'Andrea AD. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol 2004;24:5850-62.
    • (2004) Mol Cell Biol , vol.24 , pp. 5850-5862
    • Wang, X.1    Andreassen, P.R.2    D'Andrea, A.D.3
  • 17
    • 3042858785 scopus 로고    scopus 로고
    • Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
    • Hussain S, Wilson JB, Medhurst AL, et al. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum Mol Genet 2004;13:1241-8.
    • (2004) Hum Mol Genet , vol.13 , pp. 1241-1248
    • Hussain, S.1    Wilson, J.B.2    Medhurst, A.L.3
  • 18
    • 0042671242 scopus 로고    scopus 로고
    • BRCA1-independent ubiquitination of FANCD2
    • Vandenberg CJ, Gergely F, Ong CY, et al. BRCA1-independent ubiquitination of FANCD2. Mol Cell 2003;12:247-54.
    • (2003) Mol Cell , vol.12 , pp. 247-254
    • Vandenberg, C.J.1    Gergely, F.2    Ong, C.Y.3
  • 19
    • 4944229642 scopus 로고    scopus 로고
    • Hallmarks of 'BRCAness' in sporadic cancers
    • Turner N, Tutt A, Ashworth A. Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 2004;4:814-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 814-819
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 20
    • 4544374528 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: 1994 and beyond
    • Narod SA, Foulkes WD. BRCA1 and BRCA2: 1994 and beyond. Nat Rev Cancer 2004;4:665-76.
    • (2004) Nat Rev Cancer , vol.4 , pp. 665-676
    • Narod, S.A.1    Foulkes, W.D.2
  • 21
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002;108:171-82.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 22
  • 24
    • 19944414645 scopus 로고    scopus 로고
    • Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer
    • Martin ST, Matsubayashi H, Rogers CD, et al. Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer. Oncogene 2005;24:3652-6.
    • (2005) Oncogene , vol.24 , pp. 3652-3656
    • Martin, S.T.1    Matsubayashi, H.2    Rogers, C.D.3
  • 25
    • 28744457912 scopus 로고    scopus 로고
    • Genetics of the FANCA gene in familial pancreatic cancer
    • Rogers CD, Couch FJ, Brune K, et al. Genetics of the FANCA gene in familial pancreatic cancer. J Med Genet 2004;41:e126.
    • (2004) J Med Genet , vol.41
    • Rogers, C.D.1    Couch, F.J.2    Brune, K.3
  • 26
    • 0033842724 scopus 로고    scopus 로고
    • BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: Evidence and implications
    • Goggins M, Hruban RH, Kern SE. BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications. Am J Pathol 2000;156:1767-71.
    • (2000) Am J Pathol , vol.156 , pp. 1767-1771
    • Goggins, M.1    Hruban, R.H.2    Kern, S.E.3
  • 27
    • 85012433689 scopus 로고    scopus 로고
    • BRCA2 and predisposition to pancreatic and other cancers
    • Arnold MA, Goggins M. BRCA2 and predisposition to pancreatic and other cancers. Expert Rev Mol Med 2001;2001:1-10.
    • (2001) Expert Rev Mol Med , vol.2001 , pp. 1-10
    • Arnold, M.A.1    Goggins, M.2
  • 28
    • 10744233204 scopus 로고    scopus 로고
    • EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
    • Hughes-Davies L, Huntsman D, Ruas M, et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003;115:523-35.
    • (2003) Cell , vol.115 , pp. 523-535
    • Hughes-Davies, L.1    Huntsman, D.2    Ruas, M.3
  • 29
    • 2342633174 scopus 로고    scopus 로고
    • Promoter hypermethylation of FANCF: Disruption of Fanconi anemia-BRCA pathway in cervical cancer
    • Narayan G, Arias-Pulido H, Nandula SV, et al. Promoter hypermethylation of FANCF: disruption of Fanconi anemia-BRCA pathway in cervical cancer. Cancer Res 2004;64:2994-7.
    • (2004) Cancer Res , vol.64 , pp. 2994-2997
    • Narayan, G.1    Arias-Pulido, H.2    Nandula, S.V.3
  • 30
    • 1342301467 scopus 로고    scopus 로고
    • Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: Implications for treatment and survival
    • Marsit CJ, Liu M, Nelson HH, Posner M, Suzuki M, Kelsey KT. Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene 2004;23: 1000-4.
    • (2004) Oncogene , vol.23 , pp. 1000-1004
    • Marsit, C.J.1    Liu, M.2    Nelson, H.H.3    Posner, M.4    Suzuki, M.5    Kelsey, K.T.6
  • 31
    • 0038075462 scopus 로고    scopus 로고
    • Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
    • Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003;9:568-74.
    • (2003) Nat Med , vol.9 , pp. 568-574
    • Taniguchi, T.1    Tischkowitz, M.2    Ameziane, N.3
  • 32
    • 0031031009 scopus 로고    scopus 로고
    • Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S Cancer Res
    • MacDonald JR, Muscoplat CC, Dexter DL, et al. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S. Cancer Res 1997;57:279-83.
    • 1997 , vol.57 , pp. 279-283
    • MacDonald, J.R.1    Muscoplat, C.C.2    Dexter, D.L.3
  • 33
    • 0034961022 scopus 로고    scopus 로고
    • In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours
    • Sato Y, Kashimoto S, MacDonald JR, Nakano K. In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours. Eur J Cancer 2001;37:1419-28.
    • (2001) Eur J Cancer , vol.37 , pp. 1419-1428
    • Sato, Y.1    Kashimoto, S.2    MacDonald, J.R.3    Nakano, K.4
  • 34
    • 0034754269 scopus 로고    scopus 로고
    • Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice
    • Friedman HS, Keir ST, Houghton PJ, Lawless AA, Bigner DD, Waters SJ. Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice. Cancer Chemother Pharmacol 2001;48:413-6.
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 413-416
    • Friedman, H.S.1    Keir, S.T.2    Houghton, P.J.3    Lawless, A.A.4    Bigner, D.D.5    Waters, S.J.6
  • 35
    • 0033429321 scopus 로고    scopus 로고
    • Antitumor activity of MGI 114 (6-hydroxymethylacylfulvene, HMAF), a semisynthetic derivative of illudin S, against adult and pediatric human tumor colony-forming units
    • Hidalgo M, Izbicka E, Eckhardt SG, et al. Antitumor activity of MGI 114 (6-hydroxymethylacylfulvene, HMAF), a semisynthetic derivative of illudin S, against adult and pediatric human tumor colony-forming units. Anticancer Drugs 1999;10:837-44.
    • (1999) Anticancer Drugs , vol.10 , pp. 837-844
    • Hidalgo, M.1    Izbicka, E.2    Eckhardt, S.G.3
  • 36
    • 0033106003 scopus 로고    scopus 로고
    • Enhanced antitumor activity of 6-hydroxymethylacylfulvene in combination with irinotecan and 5-fluorouracil in the HT29 human colon tumor xenograft model
    • Britten CD, Hilsenbeck SG, Eckhardt SG, et al. Enhanced antitumor activity of 6-hydroxymethylacylfulvene in combination with irinotecan and 5-fluorouracil in the HT29 human colon tumor xenograft model. Cancer Res 1999;59:1049-53.
    • (1999) Cancer Res , vol.59 , pp. 1049-1053
    • Britten, C.D.1    Hilsenbeck, S.G.2    Eckhardt, S.G.3
  • 38
    • 0036021223 scopus 로고    scopus 로고
    • Enhanced antitumor activity of irofulven in combination with antimitotic agents
    • Kelner MJ, McMorris TC, Rojas RJ, et al. Enhanced antitumor activity of irofulven in combination with antimitotic agents. Invest New Drugs 2002;20:271-9.
    • (2002) Invest New Drugs , vol.20 , pp. 271-279
    • Kelner, M.J.1    McMorris, T.C.2    Rojas, R.J.3
  • 39
    • 13444303832 scopus 로고    scopus 로고
    • Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial
    • Senzer N, Arsenau J, Richards D, Berman B, MacDonald JR, Smith S. Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial. Am J Clin Oncol 2005;28:36-42.
    • (2005) Am J Clin Oncol , vol.28 , pp. 36-42
    • Senzer, N.1    Arsenau, J.2    Richards, D.3    Berman, B.4    MacDonald, J.R.5    Smith, S.6
  • 40
  • 41
    • 0028168639 scopus 로고
    • Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents
    • Kelner MJ, McMorris TC, Estes L, et al. Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents. Biochem Pharmacol 1994;48:403-9.
    • (1994) Biochem Pharmacol , vol.48 , pp. 403-409
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3
  • 42
    • 0028883899 scopus 로고
    • Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: Retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells
    • Kelner MJ, McMorris TC, Estes L, et al. Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells. Cancer Res 1995; 55:4936-40.
    • (1995) Cancer Res , vol.55 , pp. 4936-4940
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3
  • 43
    • 0037027835 scopus 로고    scopus 로고
    • Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways
    • Jaspers NG, Raams A, Kelner MJ, et al. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA Repair (Amst) 2002;1:1027-38.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 1027-1038
    • Jaspers, N.G.1    Raams, A.2    Kelner, M.J.3
  • 44
    • 4544222069 scopus 로고    scopus 로고
    • ATM-dependent CHK2 activation induced by anticancer agent, irofulven
    • Wang J, Wiltshire T, Wang Y, et al. ATM-dependent CHK2 activation induced by anticancer agent, irofulven. J Biol Chem 2004; 279:39584-92.
    • (2004) J Biol Chem , vol.279 , pp. 39584-39592
    • Wang, J.1    Wiltshire, T.2    Wang, Y.3
  • 45
    • 14244269334 scopus 로고    scopus 로고
    • Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks
    • Ismail IH, Nystrom S, Nygren J, Hammarsten O. Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks. J Biol Chem 2005; 280:4649-55.
    • (2005) J Biol Chem , vol.280 , pp. 4649-4655
    • Ismail, I.H.1    Nystrom, S.2    Nygren, J.3    Hammarsten, O.4
  • 46
    • 7044260304 scopus 로고    scopus 로고
    • Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks
    • Buscemi G, Perego P, Carenini N, et al. Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks. Oncogene 2004; 23:7691-700.
    • (2004) Oncogene , vol.23 , pp. 7691-7700
    • Buscemi, G.1    Perego, P.2    Carenini, N.3
  • 47
    • 0030797708 scopus 로고    scopus 로고
    • Recombinant ATM protein complements the cellular A-T phenotype
    • Ziv Y, Bar-Shira A, Pecker I, et al. Recombinant ATM protein complements the cellular A-T phenotype. Oncogene 1997;15:159-67.
    • (1997) Oncogene , vol.15 , pp. 159-167
    • Ziv, Y.1    Bar-Shira, A.2    Pecker, I.3
  • 48
    • 0032472330 scopus 로고    scopus 로고
    • Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
    • Cliby WA, Roberts CJ, Cimprich KA, et al. Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J 1998;17:159-69.
    • (1998) EMBO J , vol.17 , pp. 159-169
    • Cliby, W.A.1    Roberts, C.J.2    Cimprich, K.A.3
  • 51
    • 0032521537 scopus 로고    scopus 로고
    • BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II)
    • Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II). Cancer Res 1998;58:1120-3.
    • (1998) Cancer Res , vol.58 , pp. 1120-1123
    • Husain, A.1    He, G.2    Venkatraman, E.S.3    Spriggs, D.R.4
  • 52
    • 0037123768 scopus 로고    scopus 로고
    • Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways
    • Taniguchi T, Garcia-Higuera I, Xu B, et al. Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways. Cell 2002;109: 459-72.
    • (2002) Cell , vol.109 , pp. 459-472
    • Taniguchi, T.1    Garcia-Higuera, I.2    Xu, B.3
  • 53
    • 1842576658 scopus 로고    scopus 로고
    • The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-2 pathways
    • Pichierri P, Rosselli F. The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-2 pathways. EMBO J 2004;23: 1178-87.
    • (2004) EMBO J , vol.23 , pp. 1178-1187
    • Pichierri, P.1    Rosselli, F.2
  • 54
    • 4043133287 scopus 로고    scopus 로고
    • ATR couples FANCD2 monoubiquitination to the DNA-damage response
    • Andreassen PR, D'Andrea AD, Taniguchi T. ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev 2004;18: 1958-63.
    • (2004) Genes Dev , vol.18 , pp. 1958-1963
    • Andreassen, P.R.1    D'Andrea, A.D.2    Taniguchi, T.3
  • 55
    • 12844286052 scopus 로고    scopus 로고
    • Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair
    • Nakanishi K, Yang YG, Pierce AJ, et al. Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A 2005;102:1110-5.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1110-1115
    • Nakanishi, K.1    Yang, Y.G.2    Pierce, A.J.3
  • 57
    • 14644391577 scopus 로고    scopus 로고
    • The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability
    • Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Hum Mol Genet 2005;14:693-701.
    • (2005) Hum Mol Genet , vol.14 , pp. 693-701
    • Howlett, N.G.1    Taniguchi, T.2    Durkin, S.G.3    D'Andrea, A.D.4    Glover, T.W.5
  • 58
    • 0347624597 scopus 로고    scopus 로고
    • Repair kinetics of genomic interstrand DNA cross-links: Evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway
    • Rothfuss A, Grompe M. Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol 2004; 24:123-34.
    • (2004) Mol Cell Biol , vol.24 , pp. 123-134
    • Rothfuss, A.1    Grompe, M.2
  • 59
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003;3:155-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.