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Volumn 96, Issue 1, 2007, Pages 95-103

Hypoxia-inducible factor-1α expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas

Author keywords

Gastric cancer; Gastro oesophageal junction tumours; HIF 1

Indexed keywords

FORMALDEHYDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 33846189403     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603524     Document Type: Article
Times cited : (95)

References (56)
  • 1
    • 0038751965 scopus 로고    scopus 로고
    • Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression
    • Acs G, Zhang PJ, McGrath CM, Acs P, McBroom J, Mohyeldin A, Liu S, Lu H, Verma A (2003) Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am J Pathol 162: 1789-1806
    • (2003) Am J Pathol , vol.162 , pp. 1789-1806
    • Acs, G.1    Zhang, P.J.2    McGrath, C.M.3    Acs, P.4    McBroom, J.5    Mohyeldin, A.6    Liu, S.7    Lu, H.8    Verma, A.9
  • 2
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha: A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold DM, Burri P, Beer KT, Laissue J, Djonov V, Greiner RH, Semenza GL (2001) Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res 61: 2911-2916
    • (2001) Cancer Res , vol.61 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3    Laissue, J.4    Djonov, V.5    Greiner, R.H.6    Semenza, G.L.7
  • 3
    • 8544271638 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and hypoxic cell death in tumour physiology
    • Bacon AL, Harris AL (2004) Hypoxia-inducible factors and hypoxic cell death in tumour physiology. Ann Med 36: 530-539
    • (2004) Ann Med , vol.36 , pp. 530-539
    • Bacon, A.L.1    Harris, A.L.2
  • 4
    • 0036569941 scopus 로고    scopus 로고
    • Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: Relationship to tumor biology and treatment outcome in surgically resected patients
    • Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, Millard P, Fuggle S, Harris AL (2002) Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res 62: 2493-2497
    • (2002) Cancer Res , vol.62 , pp. 2493-2497
    • Beasley, N.J.1    Leek, R.2    Alam, M.3    Turley, H.4    Cox, G.J.5    Gatter, K.6    Millard, P.7    Fuggle, S.8    Harris, A.L.9
  • 6
    • 0034896068 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
    • Birner P, Schindl M, Obermair A, Breitenecker G, Oberhuber G (2001) Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin Cancer Res 7: 1661-1668
    • (2001) Clin Cancer Res , vol.7 , pp. 1661-1668
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Breitenecker, G.4    Oberhuber, G.5
  • 10
    • 20344384264 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor
    • Chen WT, Huang CJ, Wu MT, Yang SF, Su YC, Chai CY (2005b) Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. Jpn J Clin Oncol 35: 207-213
    • (2005) Jpn J Clin Oncol , vol.35 , pp. 207-213
    • Chen, W.T.1    Huang, C.J.2    Wu, M.T.3    Yang, S.F.4    Su, Y.C.5    Chai, C.Y.6
  • 12
    • 4344704061 scopus 로고    scopus 로고
    • Is gastric cancer preventable?
    • Correa P (2004) Is gastric cancer preventable? Gut 53: 1217-1219
    • (2004) Gut , vol.53 , pp. 1217-1219
    • Correa, P.1
  • 15
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
    • Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Talks K, Pezzella F, Gatter KC, Harris AL (2001) Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. Br J Cancer 85: 881-890
    • (2001) Br J Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Turley, H.4    Talks, K.5    Pezzella, F.6    Gatter, K.C.7    Harris, A.L.8
  • 16
    • 0142120661 scopus 로고    scopus 로고
    • Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin
    • Giatromanolaki A, Sivridis E, Kouskoukis C, Gatter KC, Harris AL, Koukourakis MI (2003) Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin. Melanoma Res 13: 493-501
    • (2003) Melanoma Res , vol.13 , pp. 493-501
    • Giatromanolaki, A.1    Sivridis, E.2    Kouskoukis, C.3    Gatter, K.C.4    Harris, A.L.5    Koukourakis, M.I.6
  • 17
    • 4944246547 scopus 로고    scopus 로고
    • The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
    • Greijer AE, van der Wall E (2004) The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 57: 1009-1014
    • (2004) J Clin Pathol , vol.57 , pp. 1009-1014
    • Greijer, A.E.1    van der Wall, E.2
  • 20
    • 19944429962 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: Correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix
    • Hutchison GJ, Valentine HR, Loncaster JA, Davidson SE, Hunter RD, Roberts SA, Harris AL, Stratford IJ, Price PM, West CM (2004) Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix. Clin Cancer Res 10: 8405-8412
    • (2004) Clin Cancer Res , vol.10 , pp. 8405-8412
    • Hutchison, G.J.1    Valentine, H.R.2    Loncaster, J.A.3    Davidson, S.E.4    Hunter, R.D.5    Roberts, S.A.6    Harris, A.L.7    Stratford, I.J.8    Price, P.M.9    West, C.M.10
  • 23
    • 0037245592 scopus 로고    scopus 로고
    • An improved protocol of biotinylated tyramine-based immunohistochemistry minimizing nonspecific background staining
    • Kim SH, Shin YK, Lee KM, Lee JS, Yun JH, Lee SM (2003) An improved protocol of biotinylated tyramine-based immunohistochemistry minimizing nonspecific background staining. J Histochem Cytochem 51: 129-132
    • (2003) J Histochem Cytochem , vol.51 , pp. 129-132
    • Kim, S.H.1    Shin, Y.K.2    Lee, K.M.3    Lee, J.S.4    Yun, J.H.5    Lee, S.M.6
  • 24
    • 15244344206 scopus 로고    scopus 로고
    • HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression
    • Koshiji M, To KK, Hammer S, Kumamoto K, Harris AL, Modrich P, Huang LE (2005) HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol Cell 17: 793-803
    • (2005) Mol Cell , vol.17 , pp. 793-803
    • Koshiji, M.1    To, K.K.2    Hammer, S.3    Kumamoto, K.4    Harris, A.L.5    Modrich, P.6    Huang, L.E.7
  • 25
    • 0141956303 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage
    • Kurokawa T, Miyamoto M, Kato K, Cho Y, Kawarada Y, Hida Y, Shinohara T, Itoh T, Okushiba S, Kondo S, Katoh H (2003) Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Br J Cancer 89: 1042-1047
    • (2003) Br J Cancer , vol.89 , pp. 1042-1047
    • Kurokawa, T.1    Miyamoto, M.2    Kato, K.3    Cho, Y.4    Kawarada, Y.5    Hida, Y.6    Shinohara, T.7    Itoh, T.8    Okushiba, S.9    Kondo, S.10    Katoh, H.11
  • 26
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification
    • Lauren P (1965) The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification. Acta Pathol Microbiol Scand 64: 31-49
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 27
    • 12944266844 scopus 로고    scopus 로고
    • The expression of hypoxia-inducible factor 1alpha is a favorable independent prognostic factor in renal cell carcinoma
    • Lidgren A, Hedberg Y, Grankvist K, Rasmuson T, Vasko J, Ljungberg B (2005) The expression of hypoxia-inducible factor 1alpha is a favorable independent prognostic factor in renal cell carcinoma. Clin Cancer Res 11: 1129-1135
    • (2005) Clin Cancer Res , vol.11 , pp. 1129-1135
    • Lidgren, A.1    Hedberg, Y.2    Grankvist, K.3    Rasmuson, T.4    Vasko, J.5    Ljungberg, B.6
  • 29
    • 4143118037 scopus 로고    scopus 로고
    • Lack of correlation between expression of HIF-1alpha protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix
    • Mayer A, Wree A, Hockel M, Leo C, Pilch H, Vaupel P (2004) Lack of correlation between expression of HIF-1alpha protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix. Cancer Res 64: 5876-5881
    • (2004) Cancer Res , vol.64 , pp. 5876-5881
    • Mayer, A.1    Wree, A.2    Hockel, M.3    Leo, C.4    Pilch, H.5    Vaupel, P.6
  • 30
    • 0042469448 scopus 로고    scopus 로고
    • Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases
    • Metzen E, Zhou J, Jelkmann W, Fandrey J, Brune B (2003) Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases. Mol Biol Cell 14: 3470-3481
    • (2003) Mol Biol Cell , vol.14 , pp. 3470-3481
    • Metzen, E.1    Zhou, J.2    Jelkmann, W.3    Fandrey, J.4    Brune, B.5
  • 31
    • 33747097563 scopus 로고    scopus 로고
    • Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas
    • Mizokami K, Kakeji Y, Oda S, Irie K, Yonemura T, Konishi F, Maehara Y (2006) Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas. J Surg Oncol 94: 149-154
    • (2006) J Surg Oncol , vol.94 , pp. 149-154
    • Mizokami, K.1    Kakeji, Y.2    Oda, S.3    Irie, K.4    Yonemura, T.5    Konishi, F.6    Maehara, Y.7
  • 32
    • 4043081982 scopus 로고    scopus 로고
    • Review article: Helicobacter pylori and molecular events in precancerous gastric lesions
    • Nardone G, Rocco A, Malfertheiner P (2004) Review article: Helicobacter pylori and molecular events in precancerous gastric lesions. Aliment Pharmacol Ther 20: 261-270
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 261-270
    • Nardone, G.1    Rocco, A.2    Malfertheiner, P.3
  • 33
    • 0034051262 scopus 로고    scopus 로고
    • Helicobacter pylori causes DNA damage in gastric epithelial cells
    • Obst B, Wagner S, Sewing KF, Beil W (2000) Helicobacter pylori causes DNA damage in gastric epithelial cells. Carcinogenesis 21: 1111-1115
    • (2000) Carcinogenesis , vol.21 , pp. 1111-1115
    • Obst, B.1    Wagner, S.2    Sewing, K.F.3    Beil, W.4
  • 35
    • 12244267687 scopus 로고    scopus 로고
    • Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1alpha in gastric cancer cells
    • Park JH, Kim TY, Jong HS, Chun YS, Park JW, Lee CT, Jung HC, Kim NK, Bang YJ (2003) Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1alpha in gastric cancer cells. Clin Cancer Res 9: 433-440
    • (2003) Clin Cancer Res , vol.9 , pp. 433-440
    • Park, J.H.1    Kim, T.Y.2    Jong, H.S.3    Chun, Y.S.4    Park, J.W.5    Lee, C.T.6    Jung, H.C.7    Kim, N.K.8    Bang, Y.J.9
  • 36
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek Jr RM, Blaser MJ (2002) Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2: 28-37
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek Jr, R.M.1    Blaser, M.J.2
  • 39
    • 16644363476 scopus 로고    scopus 로고
    • HIF-1 and p53: Communication of transcription factors under hypoxia
    • Schmid T, Zhou J, Brune B (2004) HIF-1 and p53: communication of transcription factors under hypoxia. J Cell Mol Med 8: 423-431
    • (2004) J Cell Mol Med , vol.8 , pp. 423-431
    • Schmid, T.1    Zhou, J.2    Brune, B.3
  • 40
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 41
    • 0031784518 scopus 로고    scopus 로고
    • Classification of adenocarcinoma of the oesophagogastric junction
    • Siewert JR, Stein HJ (1998) Classification of adenocarcinoma of the oesophagogastric junction. Br J Surg 85: 1457-1459
    • (1998) Br J Surg , vol.85 , pp. 1457-1459
    • Siewert, J.R.1    Stein, H.J.2
  • 42
    • 2942567553 scopus 로고    scopus 로고
    • Pretreatment evaluation of combined HIF-1alpha, p53 and p21 expression is a useful and sensitive indicator of response to radiation and chemotherapy in esophageal cancer
    • Sohda M, Ishikawa H, Masuda N, Kato H, Miyazaki T, Nakajima M, Fukuchi M, Manda R, Fukai Y, Sakurai H, Kuwano H (2004) Pretreatment evaluation of combined HIF-1alpha, p53 and p21 expression is a useful and sensitive indicator of response to radiation and chemotherapy in esophageal cancer. Int J Cancer 110: 838-844
    • (2004) Int J Cancer , vol.110 , pp. 838-844
    • Sohda, M.1    Ishikawa, H.2    Masuda, N.3    Kato, H.4    Miyazaki, T.5    Nakajima, M.6    Fukuchi, M.7    Manda, R.8    Fukai, Y.9    Sakurai, H.10    Kuwano, H.11
  • 44
    • 33749016506 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1{alpha} and p53 is a marker for an unfavorable prognosis in gastric cancer
    • Sumiyoshi Y, Kakeji Y, Egashira A, Mizokami K, Orita H, Maehara Y (2006) Overexpression of hypoxia-inducible factor 1{alpha} and p53 is a marker for an unfavorable prognosis in gastric cancer. Clin Cancer Res 12: 5112-5117
    • (2006) Clin Cancer Res , vol.12 , pp. 5112-5117
    • Sumiyoshi, Y.1    Kakeji, Y.2    Egashira, A.3    Mizokami, K.4    Orita, H.5    Maehara, Y.6
  • 45
    • 0035855668 scopus 로고    scopus 로고
    • Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
    • Suzuki H, Tomida A, Tsuruo T (2001) Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene 20: 5779-5788
    • (2001) Oncogene , vol.20 , pp. 5779-5788
    • Suzuki, H.1    Tomida, A.2    Tsuruo, T.3
  • 46
    • 0142175222 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach
    • Takahashi R, Tanaka S, Hiyama T, Ito M, Kitadai Y, Sumii M, Haruma K, Chayama K (2003) Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach. Oncol Rep 10: 797-802
    • (2003) Oncol Rep , vol.10 , pp. 797-802
    • Takahashi, R.1    Tanaka, S.2    Hiyama, T.3    Ito, M.4    Kitadai, Y.5    Sumii, M.6    Haruma, K.7    Chayama, K.8
  • 50
    • 0342433777 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer
    • Volm M, Koomagi R (2000) Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer Res 20: 1527-1533
    • (2000) Anticancer Res , vol.20 , pp. 1527-1533
    • Volm, M.1    Koomagi, R.2
  • 51
    • 17144416530 scopus 로고    scopus 로고
    • Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells
    • Wang V, Davis DA, Haque M, Huang LE, Yarchoan R (2005) Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells. Cancer Res 65: 3299-3306
    • (2005) Cancer Res , vol.65 , pp. 3299-3306
    • Wang, V.1    Davis, D.A.2    Haque, M.3    Huang, L.E.4    Yarchoan, R.5
  • 53
    • 11144222884 scopus 로고    scopus 로고
    • Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: Correlation with tumor angiogenesis and cyclooxygenase-2 expression
    • Yoshimura H, Dhar DK, Kohno H, Kubota H, Fujii T, Ueda S, Kinugasa S, Tachibana M, Nagasue N (2004) Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res 10: 8554-8560
    • (2004) Clin Cancer Res , vol.10 , pp. 8554-8560
    • Yoshimura, H.1    Dhar, D.K.2    Kohno, H.3    Kubota, H.4    Fujii, T.5    Ueda, S.6    Kinugasa, S.7    Tachibana, M.8    Nagasue, N.9
  • 54
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1alpha in brain tumors: Association with angiogenesis, invasion, and progression
    • Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL (2000) Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88: 2606-2618
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3    Laughner, E.4    Simons, J.W.5    Semenza, G.L.6
  • 56
    • 1842426907 scopus 로고    scopus 로고
    • Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis
    • Zhong H, Semenza GL, Simons JW, De Marzo AM (2004) Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis. Cancer Detect Prev 28: 88-93
    • (2004) Cancer Detect Prev , vol.28 , pp. 88-93
    • Zhong, H.1    Semenza, G.L.2    Simons, J.W.3    De Marzo, A.M.4


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