-
1
-
-
4644231469
-
The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR)
-
Burk, O.; Koch, I.; Raucy, J.; Hustert, E.; Eichelbaum, M.; Brockmoller, J.; Zanger, U. M.; Wojnowski, L., 2004: The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR). Journal of Biological Chemistry 279, 38379-38385.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 38379-38385
-
-
Burk, O.1
Koch, I.2
Raucy, J.3
Hustert, E.4
Eichelbaum, M.5
Brockmoller, J.6
Zanger, U.M.7
Wojnowski, L.8
-
2
-
-
14844360679
-
Effect of breed and gender on bovine liver cytochrome P450 3A (CYP3A) expression and inter-species comparison with other domestic ruminants
-
DaCasto, M.; Eeckhoute, C.; Capolongo, F.; Dupuy, J.; Carlett, M.; Calleja, C.; Nebbia, C.; Alviniere, M.; Galtier, P., 2005: Effect of breed and gender on bovine liver cytochrome P450 3A (CYP3A) expression and inter-species comparison with other domestic ruminants. Veterinary Research 36, 179-190.
-
(2005)
Veterinary Research
, vol.36
, pp. 179-190
-
-
DaCasto, M.1
Eeckhoute, C.2
Capolongo, F.3
Dupuy, J.4
Carlett, M.5
Calleja, C.6
Nebbia, C.7
Alviniere, M.8
Galtier, P.9
-
3
-
-
0033382294
-
Cytochrome P450 3A: Ontogeny and drug disposition
-
De Wildt, S. N.; Kearns, G. L.; Leeder, J. S.; van den Anker, J. N., 1999: Cytochrome P450 3A: ontogeny and drug disposition. Clinical Pharmacokinetics 37, 485-505.
-
(1999)
Clinical Pharmacokinetics
, vol.37
, pp. 485-505
-
-
De Wildt, S.N.1
Kearns, G.L.2
Leeder, J.S.3
van den Anker, J.N.4
-
4
-
-
0037016761
-
Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
-
Gerbal-Chaloin, S.; Daujat, M.; Pascussi, J. M.; Pichard-Garcia, L.; Vilarem, M. J.; Maurel, P. 2002: Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. Journal of Biological Chemistry 277, 209-217.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 209-217
-
-
Gerbal-Chaloin, S.1
Daujat, M.2
Pascussi, J.M.3
Pichard-Garcia, L.4
Vilarem, M.J.5
Maurel, P.6
-
5
-
-
33646832418
-
Ontogeny of mRNA abundance of nuclear receptors and nuclear receptor target genes in young cattle
-
in press
-
Greger, D. L.; Philipona, C.; Blum, J. W., 2006: Ontogeny of mRNA abundance of nuclear receptors and nuclear receptor target genes in young cattle. Domestic Animal Endocrinology, (in press).
-
(2006)
Domestic Animal Endocrinology
-
-
Greger, D.L.1
Philipona, C.2
Blum, J.W.3
-
6
-
-
2142661694
-
Dexamethasone and colostrum feeding affect hepatic gluconeogenic enzymes differently in neonatal calves
-
Hammon, M.; Sauter, S. N.; Reist, M.; Zbinden, Y.; Philipona, C.; Morel, C.; Blum, J. W., 2003: Dexamethasone and colostrum feeding affect hepatic gluconeogenic enzymes differently in neonatal calves. Journal of Animal Science 81, 3095-3106.
-
(2003)
Journal of Animal Science
, vol.81
, pp. 3095-3106
-
-
Hammon, M.1
Sauter, S.N.2
Reist, M.3
Zbinden, Y.4
Philipona, C.5
Morel, C.6
Blum, J.W.7
-
7
-
-
0037389946
-
Induction of bilirubin clearance by the constitutive androstane receptor (CAR)
-
Huang, W.; Zhang, J.; Chua, S. S.; Qatanani, M.; Han, Y.; Granata, R.; Moore, D. D., 2003: Induction of bilirubin clearance by the constitutive androstane receptor (CAR). Proceedings of the National Academy of Sciences of the United States of America 100, 4156-4161.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 4156-4161
-
-
Huang, W.1
Zhang, J.2
Chua, S.S.3
Qatanani, M.4
Han, Y.5
Granata, R.6
Moore, D.D.7
-
8
-
-
27644457111
-
Abundances of nuclear receptor and nuclear receptor target gene mRNA in liver and intestine of neonatal calves are differentially influenced by feeding colostrum and vitamin A
-
Krüger, K. A.; Blum, J. W.; Greger, D. L., 2005: Abundances of nuclear receptor and nuclear receptor target gene mRNA in liver and intestine of neonatal calves are differentially influenced by feeding colostrum and vitamin A. Journal of Dairy Science 88, 3971-3981.
-
(2005)
Journal of Dairy Science
, vol.88
, pp. 3971-3981
-
-
Krüger, K.A.1
Blum, J.W.2
Greger, D.L.3
-
9
-
-
0242606900
-
Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants
-
Machala, M.; Soucek, P.; Neca, J.; Ulrich, R.; Lamka, J.; Szotakova, B.; Skalova, L., 2003: Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants. Archives of Toxicology 77, 555-560.
-
(2003)
Archives of Toxicology
, vol.77
, pp. 555-560
-
-
Machala, M.1
Soucek, P.2
Neca, J.3
Ulrich, R.4
Lamka, J.5
Szotakova, B.6
Skalova, L.7
-
10
-
-
0036765785
-
Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich, J. M.; Stoltz, C. M.; Goodwin, B.; Hawkins-Brown, D.; Moore, J. T.; Kliewer, S. A., 2002: Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Molecular Pharmacology 62, 638-646.
-
(2002)
Molecular Pharmacology
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
11
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
Maglich, J. M.; Parks, D. J.; Moore, L. B.; Collins, J. L.; Goodwin, B.; Billin, A. N.; Stoltz, C. A.; Kliewer, S. A.; Lambert, M. H.; Willson, T. M.; Moore, J. T., 2003: Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. Journal of Biological Chemistry 278, 17277-17283.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
Stoltz, C.A.7
Kliewer, S.A.8
Lambert, M.H.9
Willson, T.M.10
Moore, J.T.11
-
12
-
-
2442485772
-
The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction
-
Maglich, J. M.; Watson, J.; McMillen, P. J.; Goodwin, B.; Willson, T. M.; Moore, J. T., 2004: The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction. Journal of Biological Chemistry 279, 19832-19838.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 19832-19838
-
-
Maglich, J.M.1
Watson, J.2
McMillen, P.J.3
Goodwin, B.4
Willson, T.M.5
Moore, J.T.6
-
13
-
-
0034685779
-
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
-
Moore, L. B.; Parks, D. J.; Jones, S. A.; Bledsoe, R. K.; Consler, T. G.; Stimmel, J. B.; Goodwin, B.; Liddle, C.; Blanchard, S. G.; Willson, T. M.; Collins, J. L.; Kliewer, S. A., 2000: Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. Journal of Biological Chemistry 275, 15122-15127.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 15122-15127
-
-
Moore, L.B.1
Parks, D.J.2
Jones, S.A.3
Bledsoe, R.K.4
Consler, T.G.5
Stimmel, J.B.6
Goodwin, B.7
Liddle, C.8
Blanchard, S.G.9
Willson, T.M.10
Collins, J.L.11
Kliewer, S.A.12
-
14
-
-
0033931266
-
Dexamethasone induces pregnane X receptor and retinoid X receptor-alphaexpression in human hepatocytes: Synergistic increase of CYP3A4 induction by pregnane X receptor activators
-
Pascussi, J. M.; Drocourt, L.; Fabre, J. M.; Maurel, P.; Vilarem, M. J., 2000a: Dexamethasone induces pregnane X receptor and retinoid X receptor-alphaexpression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators. Molecular Pharmacology 58, 361-372.
-
(2000)
Molecular Pharmacology
, vol.58
, pp. 361-372
-
-
Pascussi, J.M.1
Drocourt, L.2
Fabre, J.M.3
Maurel, P.4
Vilarem, M.J.5
-
15
-
-
0033664347
-
Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation
-
Pascussi, J. M.; Gerbal-Chaloin, S.; Fabre, J. M.; Maurel, P.; Vilarem, M. J., 2000b: Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation. Molecular Pharmacology 58, 1441-1450.
-
(2000)
Molecular Pharmacology
, vol.58
, pp. 1441-1450
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Fabre, J.M.3
Maurel, P.4
Vilarem, M.J.5
-
16
-
-
0035659943
-
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
-
Pascussi, J. M.; Drocourt, L.; Gerbal-Chaloin, S.; Fabre, J. M.; Maurel, P.; Vilarem, M. J., 2001: Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor. European Journal of Biochemistry 268, 6346-6358.
-
(2001)
European Journal of Biochemistry
, vol.268
, pp. 6346-6358
-
-
Pascussi, J.M.1
Drocourt, L.2
Gerbal-Chaloin, S.3
Fabre, J.M.4
Maurel, P.5
Vilarem, M.J.6
-
17
-
-
12244277409
-
Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: Identification of a distal glucocorticoid response element
-
Pascussi, J. M.; Busson-Le Coniat, M.; Maurel, P.; Vilarem, M. J., 2003: Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: identification of a distal glucocorticoid response element. Molecular Endocrinology 17, 42-55.
-
(2003)
Molecular Endocrinology
, vol.17
, pp. 42-55
-
-
Pascussi, J.M.1
Busson-Le Coniat, M.2
Maurel, P.3
Vilarem, M.J.4
-
18
-
-
0037972688
-
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor
-
Rosenfeld, J. M.; Vargas, R. Jr.; Xie, W.; Evans, R. M., 2003: Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Molecular Endocrinology 17, 1268-1282.
-
(2003)
Molecular Endocrinology
, vol.17
, pp. 1268-1282
-
-
Rosenfeld, J.M.1
Vargas Jr., R.2
Xie, W.3
Evans, R.M.4
-
19
-
-
0042804816
-
Effects of dexamethasone and colostrum intake on the somatotropic axis in neonatal calves
-
Sauter, S. N.; Ontsouka, E.; Roffler, B.; Zbinden, Y.; Philipona, C.; Pfaffl, M.; Breier, B. H.; Blum, J. W.; Hammon, H. M., 2003: Effects of dexamethasone and colostrum intake on the somatotropic axis in neonatal calves. American Journal of Physiology 285, E252-E261.
-
(2003)
American Journal of Physiology
, vol.285
-
-
Sauter, S.N.1
Ontsouka, E.2
Roffler, B.3
Zbinden, Y.4
Philipona, C.5
Pfaffl, M.6
Breier, B.H.7
Blum, J.W.8
Hammon, H.M.9
-
20
-
-
33846070557
-
Effects of colostrum feeding and glucocorticoid administration on insulin-dependent glucose metabolism in neonatal calves
-
in press
-
Scheuer, B. H.; Zbinden, Y.; Schneiter, P.; Tappy, L.; Blum, J. W.; Hammon, H. M., 2005: Effects of colostrum feeding and glucocorticoid administration on insulin-dependent glucose metabolism in neonatal calves. Domestic Animal Endocrinology, (in press).
-
(2005)
Domestic Animal Endocrinology
-
-
Scheuer, B.H.1
Zbinden, Y.2
Schneiter, P.3
Tappy, L.4
Blum, J.W.5
Hammon, H.M.6
-
21
-
-
8344219885
-
Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver
-
Squires, E. J.; Sueyoshi, T.; Negishi, M., 2004: Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver. Journal of Biological Chemistry 279, 49307-49314.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 49307-49314
-
-
Squires, E.J.1
Sueyoshi, T.2
Negishi, M.3
-
22
-
-
14944341677
-
Transcriptional regulation of human UGT1A1 gene expression activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor mediated UDP-glucuronosyltransfersase 1A1 regulation with glucocorticoid receptor-interacting protein 1
-
Sugatani, J.; Nishitani, S.; Yamakawa, K.; Yoshinari, K.; Sueyoshi, T.; Negishi, M.; Miwa, M., 2005: Transcriptional regulation of human UGT1A1 gene expression activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor mediated UDP-glucuronosyltransfersase 1A1 regulation with glucocorticoid receptor-interacting protein 1. Molecular Pharmacology 67, 845-855.
-
(2005)
Molecular Pharmacology
, vol.67
, pp. 845-855
-
-
Sugatani, J.1
Nishitani, S.2
Yamakawa, K.3
Yoshinari, K.4
Sueyoshi, T.5
Negishi, M.6
Miwa, M.7
-
23
-
-
23044436687
-
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
-
Wagner, M.; Halilbasic, E.; Marschall, H. U.; Zollner, G.; Fickert, P.; Langner, C.; Zatloukal, K.; Denk, H.; Trauner, M., 2005: CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Hepatology 42, 420-430.
-
(2005)
Hepatology
, vol.42
, pp. 420-430
-
-
Wagner, M.1
Halilbasic, E.2
Marschall, H.U.3
Zollner, G.4
Fickert, P.5
Langner, C.6
Zatloukal, K.7
Denk, H.8
Trauner, M.9
-
24
-
-
0346099111
-
Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes
-
Wang, H.; LeCluyse, E. L., 2003: Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes. Clinical Pharmacokinetics 42, 1331-1357.
-
(2003)
Clinical Pharmacokinetics
, vol.42
, pp. 1331-1357
-
-
Wang, H.1
LeCluyse, E.L.2
-
25
-
-
0034687397
-
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
-
Wei, P.; Zhang, J.; Egan-Hafley, M.; Liang, S.; Moore, D. D., 2000: The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407, 920-923.
-
(2000)
Nature
, vol.407
, pp. 920-923
-
-
Wei, P.1
Zhang, J.2
Egan-Hafley, M.3
Liang, S.4
Moore, D.D.5
-
26
-
-
0036367792
-
Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response
-
Wei, P.; Zhang, J.; Dowhan, D. H.; Han, Y.; Moore, D. D., 2002: Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response. Pharmacogenomics Journal 2, 117-126.
-
(2002)
Pharmacogenomics Journal
, vol.2
, pp. 117-126
-
-
Wei, P.1
Zhang, J.2
Dowhan, D.H.3
Han, Y.4
Moore, D.D.5
-
27
-
-
0037223832
-
The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity
-
Yamamoto, Y.; Kawamoto, T.; Negishi, M., 2003: The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity. Archives of Biochemistry and Biophysics 409, 207-211.
-
(2003)
Archives of Biochemistry and Biophysics
, vol.409
, pp. 207-211
-
-
Yamamoto, Y.1
Kawamoto, T.2
Negishi, M.3
|