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Volumn 66, Issue 1, 2007, Pages 86-97

Upregulation of hypoxia-inducible factor (HIF)-1α and HIF-2α in leptomeningeal vascular malformations of Sturge-Weber Syndrome

Author keywords

Angiogenesis; Cerebral ischemia; Hypoxia inducible factor (HIF); Sturge Weber Syndrome; Vascular endothelial growth factor (VEGF); Vascular malformation

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; NEUROPILIN 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 33846078395     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/nen.0b013e31802d9011     Document Type: Article
Times cited : (43)

References (54)
  • 1
    • 0041382226 scopus 로고    scopus 로고
    • Pathophysiology of Sturge-Weber syndrome
    • Comi AM. Pathophysiology of Sturge-Weber syndrome. J Child Neurol 2003;18:509-16
    • (2003) J Child Neurol , vol.18 , pp. 509-516
    • Comi, A.M.1
  • 2
    • 0036556248 scopus 로고    scopus 로고
    • A locus for hereditary capillary malformations mapped on chromosome 5q
    • Breugem CC, Alders M, Salieb-Beugelaar GB, et al. A locus for hereditary capillary malformations mapped on chromosome 5q. Hum Genet 2002;110:343-47
    • (2002) Hum Genet , vol.110 , pp. 343-347
    • Breugem, C.C.1    Alders, M.2    Salieb-Beugelaar, G.B.3
  • 4
    • 0029008863 scopus 로고
    • Regional cerebral blood flow and metabolism in Sturge-Weber disease
    • Duncan DB, Herholz K, Pietrzyk U, et al. Regional cerebral blood flow and metabolism in Sturge-Weber disease. Clin Nucl Med 1995;20:522-523
    • (1995) Clin Nucl Med , vol.20 , pp. 522-523
    • Duncan, D.B.1    Herholz, K.2    Pietrzyk, U.3
  • 5
    • 0035943004 scopus 로고    scopus 로고
    • Sturge-Weber syndrome: Correlation between clinical course and FDG PET findings
    • Lee JS, Asano E, Muzik O, et al. Sturge-Weber syndrome: Correlation between clinical course and FDG PET findings. Neurology 2001;57:189-95
    • (2001) Neurology , vol.57 , pp. 189-195
    • Lee, J.S.1    Asano, E.2    Muzik, O.3
  • 6
    • 0034648793 scopus 로고    scopus 로고
    • Vascular-specific growth factors and blood vessel formation
    • Yancopoulos GD, Davis S, Gale NW, et al. Vascular-specific growth factors and blood vessel formation. Nature 2000;407:242-48
    • (2000) Nature , vol.407 , pp. 242-248
    • Yancopoulos, G.D.1    Davis, S.2    Gale, N.W.3
  • 7
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996;380:439-42
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 8
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-39
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3
  • 9
    • 0029006696 scopus 로고
    • Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
    • Shalaby F, Rossant J, Yamaguchi TP, et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 1995;376:62-66
    • (1995) Nature , vol.376 , pp. 62-66
    • Shalaby, F.1    Rossant, J.2    Yamaguchi, T.P.3
  • 10
    • 0032707249 scopus 로고    scopus 로고
    • A requirement for neuropilin-1 in embryonic vessel formation
    • Kawasaki T, Kitsukawa T, Bekku Y, et al. A requirement for neuropilin-1 in embryonic vessel formation. Development 1999;126:4895-902
    • (1999) Development , vol.126 , pp. 4895-4902
    • Kawasaki, T.1    Kitsukawa, T.2    Bekku, Y.3
  • 11
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S, Takashima S, Miao HQ, et al. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998;92:735-45
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3
  • 12
    • 0029001244 scopus 로고
    • Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
    • Sato TN, Tozawa Y, Deutsch U, et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995;376:70-74
    • (1995) Nature , vol.376 , pp. 70-74
    • Sato, T.N.1    Tozawa, Y.2    Deutsch, U.3
  • 14
    • 0036380377 scopus 로고    scopus 로고
    • A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
    • Acker T, Plate KH. A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology. J Mol Med 2002;80:562-75
    • (2002) J Mol Med , vol.80 , pp. 562-575
    • Acker, T.1    Plate, K.H.2
  • 15
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • Ryan HE, Lo J, Johnson RS. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J 1998;17:3005-15
    • (1998) EMBO J , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 16
    • 15444342958 scopus 로고    scopus 로고
    • Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
    • Iyer NV, Kotch LE, Agani F, et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998;12:149-62
    • (1998) Genes Dev , vol.12 , pp. 149-162
    • Iyer, N.V.1    Kotch, L.E.2    Agani, F.3
  • 17
    • 0030943461 scopus 로고    scopus 로고
    • Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
    • Maltepe E, Schmidt JV, Baunoch D, et al. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 1997;386:403-7
    • (1997) Nature , vol.386 , pp. 403-407
    • Maltepe, E.1    Schmidt, J.V.2    Baunoch, D.3
  • 18
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, et al. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem 1997;272:23659-67
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3
  • 19
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian H, McKnight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 1997;11:72-82
    • (1997) Genes Dev , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 20
    • 0034765091 scopus 로고    scopus 로고
    • Coexpression of endothelial PAS protein 1 with essential angiogenic factors suggests its involvement in human vascular development
    • Favier J, Kempf H, Corvol P, et al. Coexpression of endothelial PAS protein 1 with essential angiogenic factors suggests its involvement in human vascular development. Dev Dyn 2001;222:377-88
    • (2001) Dev Dyn , vol.222 , pp. 377-388
    • Favier, J.1    Kempf, H.2    Corvol, P.3
  • 21
    • 0037470245 scopus 로고    scopus 로고
    • Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)
    • Elvert G, Kappel A, Heidenreich R, et al. Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). J Biol Chem 2003;278:7520-30
    • (2003) J Biol Chem , vol.278 , pp. 7520-7530
    • Elvert, G.1    Kappel, A.2    Heidenreich, R.3
  • 22
    • 32044468535 scopus 로고    scopus 로고
    • A reassessment of vascular endothelial growth factor in central nervous system pathology
    • Merrill MJ, Oldfield EH. A reassessment of vascular endothelial growth factor in central nervous system pathology. J Neurosurg 2005;103:853-68
    • (2005) J Neurosurg , vol.103 , pp. 853-868
    • Merrill, M.J.1    Oldfield, E.H.2
  • 23
    • 18244390729 scopus 로고    scopus 로고
    • Coexpression of angiogenic factors in brain arteriovenous malformations
    • Hashimoto T, Wu Y, Lawton MT, et al. Coexpression of angiogenic factors in brain arteriovenous malformations. Neurosurgery 2005;56:1058-65
    • (2005) Neurosurgery , vol.56 , pp. 1058-1065
    • Hashimoto, T.1    Wu, Y.2    Lawton, M.T.3
  • 24
    • 0033678506 scopus 로고    scopus 로고
    • Expression of angiopoietin-1, angiopoietin-2, and tie receptors after middle cerebral artery occlusion in the rat
    • Beck H, Acker T, Wiessner C, et al. Expression of angiopoietin-1, angiopoietin-2, and tie receptors after middle cerebral artery occlusion in the rat. Am J Pathol 2000;157:1473-83
    • (2000) Am J Pathol , vol.157 , pp. 1473-1483
    • Beck, H.1    Acker, T.2    Wiessner, C.3
  • 25
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, et al. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992;359:845-48
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3
  • 26
    • 0344838615 scopus 로고    scopus 로고
    • Heterologous expression of human VEGF165 in rat brain: Dose-dependent, heterogeneous effects on CBF in relation to vascular density and cross-sectional area
    • Vogel J, Horner C, Haller C, et al. Heterologous expression of human VEGF165 in rat brain: Dose-dependent, heterogeneous effects on CBF in relation to vascular density and cross-sectional area. J Cereb Blood Flow Metab 2003;23:423-31
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 423-431
    • Vogel, J.1    Horner, C.2    Haller, C.3
  • 27
    • 3843114299 scopus 로고    scopus 로고
    • VEGF-A angiogenesis induces a stable neovasculature in adult murine brain
    • Stiver SI, Tan X, Brown LF, et al. VEGF-A angiogenesis induces a stable neovasculature in adult murine brain. J Neuropathol Exp Neurol 2004;63:841-55
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 841-855
    • Stiver, S.I.1    Tan, X.2    Brown, L.F.3
  • 28
    • 0032499694 scopus 로고    scopus 로고
    • Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo
    • Rosenstein JM, Mani N, Silverman WF, et al. Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo. Proc Natl Acad Sci USA 1998;95:7086-91
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7086-7091
    • Rosenstein, J.M.1    Mani, N.2    Silverman, W.F.3
  • 29
    • 0036524018 scopus 로고    scopus 로고
    • Intraventricular infusion of vascular endothelial growth factor promotes cerebral angiogenesis with minimal brain edema
    • Harrigan MR, Ennis SR, Masada T, et al. Intraventricular infusion of vascular endothelial growth factor promotes cerebral angiogenesis with minimal brain edema. Neurosurgery 2002;50:589-98
    • (2002) Neurosurgery , vol.50 , pp. 589-598
    • Harrigan, M.R.1    Ennis, S.R.2    Masada, T.3
  • 30
    • 0029865645 scopus 로고    scopus 로고
    • Expression of angiogenic factors and structural proteins in central nervous system vascular malformations
    • Rothbart D, Awad IA, Lee J, et al. Expression of angiogenic factors and structural proteins in central nervous system vascular malformations. Neurosurgery 1996;38:915-24
    • (1996) Neurosurgery , vol.38 , pp. 915-924
    • Rothbart, D.1    Awad, I.A.2    Lee, J.3
  • 31
    • 0036371086 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factors and their receptors in and around intracranial arteriovenous malformations
    • Koizumi T, Shiraishi T, Hagihara N, et al. Expression of vascular endothelial growth factors and their receptors in and around intracranial arteriovenous malformations. Neurosurgery 2002;50:117-24
    • (2002) Neurosurgery , vol.50 , pp. 117-124
    • Koizumi, T.1    Shiraishi, T.2    Hagihara, N.3
  • 32
    • 0342424375 scopus 로고    scopus 로고
    • Expression of structural proteins and angiogenic factors in cerebrovascular anomalies
    • Kilic T, Pamir MN, Kullu S, et al. Expression of structural proteins and angiogenic factors in cerebrovascular anomalies. Neurosurgery 2000;46:1179-91
    • (2000) Neurosurgery , vol.46 , pp. 1179-1191
    • Kilic, T.1    Pamir, M.N.2    Kullu, S.3
  • 33
    • 0025061633 scopus 로고
    • MR-imaging findings in children with Sturge-Weber syndrome
    • Sperner J, Schmauser I, Bittner R, et al. MR-imaging findings in children with Sturge-Weber syndrome. Neuropediatrics 1990;21:146-52
    • (1990) Neuropediatrics , vol.21 , pp. 146-152
    • Sperner, J.1    Schmauser, I.2    Bittner, R.3
  • 34
    • 0027273234 scopus 로고
    • The Sturge-Weber syndrome: Correlation between the clinical status and radiological CT and MRI findings
    • Marti-Bonmati L, Menor F, Mulas F. The Sturge-Weber syndrome: Correlation between the clinical status and radiological CT and MRI findings. Childs Nerv Syst 1993;9:107-9
    • (1993) Childs Nerv Syst , vol.9 , pp. 107-109
    • Marti-Bonmati, L.1    Menor, F.2    Mulas, F.3
  • 35
    • 0029845766 scopus 로고    scopus 로고
    • Impaired autoregulation in an experimental model of chronic cerebral hypoperfusion in rats
    • Irikura K, Morii S, Miyasaka Y, et al. Impaired autoregulation in an experimental model of chronic cerebral hypoperfusion in rats. Stroke 1996;27:1399-404
    • (1996) Stroke , vol.27 , pp. 1399-1404
    • Irikura, K.1    Morii, S.2    Miyasaka, Y.3
  • 36
    • 0034866624 scopus 로고    scopus 로고
    • Endothelial proliferation, neoangiogenesis, and potential de novo generation of cerebrovascular malformations
    • Sure U, Butz N, Schlegel J, et al. Endothelial proliferation, neoangiogenesis, and potential de novo generation of cerebrovascular malformations. J Neurosurg 2001;94:972-77
    • (2001) J Neurosurg , vol.94 , pp. 972-977
    • Sure, U.1    Butz, N.2    Schlegel, J.3
  • 37
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 38
    • 0032440901 scopus 로고    scopus 로고
    • Central nervous system structure and function in Sturge-Weber syndrome: Evidence of neurologic and radiologic progression
    • Maria BL, Neufeld JA, Rosainz LC, et al. Central nervous system structure and function in Sturge-Weber syndrome: Evidence of neurologic and radiologic progression. J Child Neurol 1998;13:606-18
    • (1998) J Child Neurol , vol.13 , pp. 606-618
    • Maria, B.L.1    Neufeld, J.A.2    Rosainz, L.C.3
  • 39
    • 0034818275 scopus 로고    scopus 로고
    • Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and-2 suggests an important role of astrocytes in cerebellar vascularization
    • Acker T, Beck H, Plate KH. Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and-2 suggests an important role of astrocytes in cerebellar vascularization. Mech Dev 2001;108:45-57
    • (2001) Mech Dev , vol.108 , pp. 45-57
    • Acker, T.1    Beck, H.2    Plate, K.H.3
  • 40
    • 0035108689 scopus 로고    scopus 로고
    • Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations
    • Uranishi R, Baev NI, Ng PY, et al. Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations. Neurosurgery 2001;48:359-67
    • (2001) Neurosurgery , vol.48 , pp. 359-367
    • Uranishi, R.1    Baev, N.I.2    Ng, P.Y.3
  • 41
    • 13544251374 scopus 로고    scopus 로고
    • A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia
    • Brusselmans K, Bono F, Collen D, et al. A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia. J Biol Chem 2005;280:3493-99
    • (2005) J Biol Chem , vol.280 , pp. 3493-3499
    • Brusselmans, K.1    Bono, F.2    Collen, D.3
  • 42
    • 0033970878 scopus 로고    scopus 로고
    • PR39, a peptide regulator of angiogenesis
    • Li J, Post M, Volk R, et al. PR39, a peptide regulator of angiogenesis. Nat Med 2000;6:49-55
    • (2000) Nat Med , vol.6 , pp. 49-55
    • Li, J.1    Post, M.2    Volk, R.3
  • 43
    • 7944224442 scopus 로고    scopus 로고
    • Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
    • Tang N, Wang L, Esko J, et al. Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 2004;6:485-95
    • (2004) Cancer Cell , vol.6 , pp. 485-495
    • Tang, N.1    Wang, L.2    Esko, J.3
  • 44
    • 30444442692 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development
    • Licht AH, Muller-Holtkamp F, Flamme I, et al. Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development. Blood 2006;107:584-90
    • (2006) Blood , vol.107 , pp. 584-590
    • Licht, A.H.1    Muller-Holtkamp, F.2    Flamme, I.3
  • 45
    • 0030476061 scopus 로고    scopus 로고
    • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
    • Kimura H, Braun RD, Ong ET, et al. Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res 1996;56:5522-28
    • (1996) Cancer Res , vol.56 , pp. 5522-5528
    • Kimura, H.1    Braun, R.D.2    Ong, E.T.3
  • 46
    • 14844295053 scopus 로고    scopus 로고
    • Biological activity of adult cavernous malformations: A study of 56 patients
    • Sure U, Freman S, Bozinov O, et al. Biological activity of adult cavernous malformations: a study of 56 patients. J Neurosurg 2005;102:342-47
    • (2005) J Neurosurg , vol.102 , pp. 342-347
    • Sure, U.1    Freman, S.2    Bozinov, O.3
  • 47
    • 0037337061 scopus 로고    scopus 로고
    • The subtle side to hypoxia inducible factor (HIFalpha) regulation
    • Bilton RL, Booker GW. The subtle side to hypoxia inducible factor (HIFalpha) regulation. Eur J Biochem 2003;270:791-98
    • (2003) Eur J Biochem , vol.270 , pp. 791-798
    • Bilton, R.L.1    Booker, G.W.2
  • 48
    • 0033566693 scopus 로고    scopus 로고
    • Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
    • Feldser D, Agani F, Iyer NV, et al. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res 1999;59:3915-18
    • (1999) Cancer Res , vol.59 , pp. 3915-3918
    • Feldser, D.1    Agani, F.2    Iyer, N.V.3
  • 49
    • 18544365990 scopus 로고    scopus 로고
    • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
    • Tomlinson IP, Alam NA, Rowan AJ, et al. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet 2002;30:406-10
    • (2002) Nat Genet , vol.30 , pp. 406-410
    • Tomlinson, I.P.1    Alam, N.A.2    Rowan, A.J.3
  • 50
    • 0034602950 scopus 로고    scopus 로고
    • Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
    • Baysal BE, Ferrell RE, Willett-Brozick JE, et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 2000;287:848-51
    • (2000) Science , vol.287 , pp. 848-851
    • Baysal, B.E.1    Ferrell, R.E.2    Willett-Brozick, J.E.3
  • 51
    • 19944433653 scopus 로고    scopus 로고
    • Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
    • Selak MA, Armour SM, MacKenzie ED, et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 2005;7:77-85
    • (2005) Cancer Cell , vol.7 , pp. 77-85
    • Selak, M.A.1    Armour, S.M.2    MacKenzie, E.D.3
  • 52
    • 23644448721 scopus 로고    scopus 로고
    • HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
    • Isaacs JS, Jung YJ, Mole DR, et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability. Cancer Cell 2005;8:143-53
    • (2005) Cancer Cell , vol.8 , pp. 143-153
    • Isaacs, J.S.1    Jung, Y.J.2    Mole, D.R.3
  • 53
    • 33644748673 scopus 로고    scopus 로고
    • pVHL function is essential for endothelial extracellular matrix deposition
    • Tang N, Mack F, Haase VH, et al. pVHL function is essential for endothelial extracellular matrix deposition. Mol Cell Biol 2006;26:2519-30
    • (2006) Mol Cell Biol , vol.26 , pp. 2519-2530
    • Tang, N.1    Mack, F.2    Haase, V.H.3
  • 54
    • 24344507686 scopus 로고    scopus 로고
    • Sturge-Weber syndrome: Altered blood vessel fibronectin expression and morphology
    • Comi AM, Weisz CJ, Highet BH, et al. Sturge-Weber syndrome: Altered blood vessel fibronectin expression and morphology. J Child Neurol 2005;20:572-77
    • (2005) J Child Neurol , vol.20 , pp. 572-577
    • Comi, A.M.1    Weisz, C.J.2    Highet, B.H.3


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