The lack of cardiotrophin-1 alters expression of interleukin-6 and leukemia inhibitory factor mRNA but does not impair cardiac injury response

Cytokine

Volumn 36, Issue 1-2, 2006, Pages 9-16

  Gritman, Kurt ^a   Van Winkle, Donna M ^b,c   Lorentz, Christina U ^a   Pennica, Diane ^d   Habecker, Beth A ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PORTLAND VA MEDICAL CENTER   (United States)

^d GENENTECH INC   (United States)

Author keywords

Cardiac protection; Cardiotrophin 1; gp130; Interleukin 6; Leukemia inhibitory factor

Indexed keywords

CARDIOTROPHIN 1; DOBUTAMINE; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; GANGLION BLOCK; GENOTYPE; HEART INFARCTION; HEART INFARCTION SIZE; HEART INJURY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE; HEART VENTRICLE PRESSURE; MOUSE; NONHUMAN; PARAMETER; PREGANGLIONIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; SYMPATHETIC NERVE;

ANIMALS; BODY WEIGHT; CYTOKINES; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEART INJURIES; HEART RATE; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; MICE; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; ORGAN SIZE; RNA, MESSENGER;

MUS;

EID: 33846026388     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2006.10.004     Document Type: Article

References (46)

1. Pennica D., King K.L., Shaw K.J., Luis E., Rullamas J., Luoh S.M., et al. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA 92 (1995) 1142-1146
2. Wollert K.C., Taga T., Saito M., Narazaki M., Kishimoto T., Glembotski C.C., et al. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series via gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem 271 (1996) 9535-9545
3. Taga T., and Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 15 (1997) 797-819
4. Heinrich P.C., Behrmann I., Müller-Newen G., Schaper F., and Graeve L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 334 (1998) 297-314
5. Heinrich P.C., Behrmann I., Haan S., Hermanns H.M., Muller-Newen G., and Schaper F. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374 (2003) 1-20
6. Sheng Z., Pennica D., Wood W.I., and Chien K.R. Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival. Development 122 (1996) 419-428
7. Sheng Z., Knowlton K., Chen J., Hoshijima M., Brown J.H., and Chien K.R. Cardiotrophin 1(CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy. J Biol Chem 272 (1997) 5783-5791
8. Brar B.K., Stephanou A., Liao Z., O'Leary R.M., Pennica D., Yellon D.M., et al. Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation. Cardiovasc Res 51 (2001) 265-274
9. Liao Z., Brar B.K., Cai Q., Stephanou A., O'Leary R.M., Pennica D., et al. Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion. Cardiovasc Res 53 (2002) 902-910
10. Yoshida K., Taga T., Saito M., Suematsu S., Kumanogoh A., Tanaka T., et al. Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci USA 93 (1996) 407-411
11. Betz U.A.K., Bloch W., van den Broek M., Yoshida K., Taga T., Kishimoto T., et al. Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects. J Exp Med 188 (1998) 1955-1965
12. Oppenheim R.W., Wiese S., Prevette D., Armanini M., Wang S., Houenou L.J., et al. Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons. J Neurosci 21 (2001) 1283-1291
13. Ruixing Y., Dezhai Y., and Jiaquan L. Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction. J Med Invest 51 (2004) 29-37
14. Ghosh S., Ng L.L., Talwar S., Squire I.B., and Galinanes M. Cardiotrophin-1 protects the human myocardium from ischemic injury. Comparison with the first and second window of protection by ischemic preconditioning. Cardiovasc Res 48 (2000) 440-447
15. Aoyama T., Takimoto Y., Pennica D., Inoue R., Shinoda E., Hattori R., et al. Augmented expression of cardiotrophin-1 and its receptor component, gp130, in both left and right ventricles after myocardial infarction in the rat. J Mol Cell Cardiol 32 (2000) 1821-1830
16. Freed D.H., Moon M.C., Borowiec A.M., Jones S.C., Zahradka P., and Dixon I.M. Cardiotrophin-1: expression in experimental myocardial infarction and potential role in post-MI wound healing. Mol Cell Biochem 254 (2003) 247-256
17. Holtmann B., Wiese S., Samsam M., Grohmann K., Pennica D., Martini R., et al. Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function. J Neurosci 25 (2005) 1778-1787
18. Oberle S., Schober A., Meyer V., Holtmann B., Henderson C., Sendtner M., et al. Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci 26 (2006) 1823-1832
19. Wolff R.A., Chien G.L., and Van Winkle D.M. Propidium iodide compares favorably with histology and triphenyl tetrazolium chloride in the assessment of experimentally-induced infarct size. J Mol Cell Cardiol 32 (2000) 225-232
20. Aizawa-Abe M., Ogawa Y., Masuzaki H., Ebihara K., Satoh N., Iwai H., et al. Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 105 (2000) 1243-1252
21. Derouet D., Rousseau F., Alfonsi F., Froger J., Hermann J., Barbier F., et al. Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor. Proc Natl Acad Sci USA 101 (2004) 4827-4832
22. Chandrasekar B., Mitchell D.H., Colston J.T., and Freeman G.L. Regulation of CCAAT/Enhancer binding protein, interleukin-6, interleukin-6 receptor, and gp130 expression during myocardial ischemia/reperfusion. Circulation 99 (1999) 427-433
23. Gwechenberger M., Mendoza L.H., Youker K.A., Frangogiannis N.G., Smith C.W., Michael L.H., et al. Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions. Circulation 99 (1999) 546-551
24. Kucia M., Dawn B., Hunt G., Guo Y., Wysoczynski M., Majka M., et al. Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ Res 95 (2004) 1191-1199
25. Zou Y., Takano H., Mizukami M., Akazawa H., Qin Y., Toko H., et al. Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction. Circulation 108 (2003) 748-753
26. Ono K., Matsumori A., Shioi T., Furukawa Y., and Sasayama S. Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling. Circulation 98 (1998) 149-156
27. Wollert K.C., and Chien K.R. Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development. J Mol Med 75 (1997) 492-501
28. Escary J.L., Perreau J., Dumenil D., Ezine S., and Brulet P. Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation. Nature 363 (1993) 361-364
29. Stewart C.L., Kaspar P., Brunet L.J., Bhatt H., Gadi I., Kontgen F., et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 359 (1992) 76-79
30. Ware C.B., Horowitz M.C., Renshaw B.R., Hunt J.S., Liggitt D., Koblar S.A., et al. Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Development 121 (1995) 1283-1299
31. Hirota H., Yoshida K., Kishimoto T., and Taga T. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA 92 (1995) 4862-4866
32. Hamanaka I., Saito Y., Nishikimi T., Magaribuchi T., Kamitani S., Kuwahara K., et al. Effects of cardiotrophin-1 on hemodynamics and endocrine function of the heart. Am J Physiol Heart Circ Physiol 279 (2000) H388-H396
33. Jin H., Yang R., Ko A., Pennica D., Wood W.I., and Paoni N.F. Effects of cardiotrophin-1 on haemodynamics and cardiac function in conscious rats. Cytokine 10 (1998) 19-25
34. Yao L., Kohno M., Noma T., Murakami K., Tsuji T., Yu Y., et al. Acute effect of human cardiotrophin-1 on hemodynamic parameters in spontaneously hypertensive rats and Wistar Kyoto rats. Hypertens Res 24 (2001) 717-721
35. Yamaguchi N., de Champlain J., and Nadeau R. Correlation between the response of the heart to sympathetic stimulation and the release of endogenous catecholamines into the coronary sinus of the dog. Circ Res 36 (1975) 662-668
36. Cao W.H., and Morrison S.F. Disinhibition of rostral raphe pallidus neurons increases cardiac sympathetic nerve activity and heart rate. Brain Res 980 (2003) 1-10
37. Esler M., Lambert G., Brunner-La Rocca H.P., Vaddadi G., and Kaye D. Sympathetic nerve activity and neurotransmitter release in humans: translation from pathophysiology into clinical practice. Acta Physiol Scand 177 (2003) 275-284
38. Stephanou A., Brar B., Heads R., Knight R.D., Marber M.S., Pennica D., et al. Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli. J Mol Cell Cardiol 30 (1998) 849-855
39. Talwar S., Squire I.B., O'brien R.J., Downie P.F., Davies J.E., and Ng L.L. Plasma cardiotrophin-1 following acute myocardial infarction: relationship with left ventricular systolic dysfunction. Clin Sci (Lond) 102 (2002) 9-14
40. Brar B.K., Stephanou A., Pennica D., and Latchman D.S. CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways. Cytokine 16 (2001) 93-96
41. Kunisada K., Tone E., Fujio Y., Matsui H., Yamauchi-Takihara K., and Kishimoto T. Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes. Circulation 98 (1998) 346-352
42. Fuchs M., Hilfiker A., Kaminski K., Hilfiker-Kleiner D., Guener Z., Klein G., et al. Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction. FASEB J 17 (2003) 2118-2120
43. Kunisada K., Hirota H., Fujio Y., Matsui H., Tani Y., Yamauchi-Takihara K., et al. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes. Circulation 94 (1996) 2626-2632
44. Yasukawa H., Hoshijima M., Gu Y., Nakamura T., Pradervand S., Hanada T., et al. Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways. J Clin Invest 108 (2001) 1459-1467
45. Masu Y., Wolf E., Holtmann B., Sendtner M., Brem G., and Thoenen H. Disruption of the CNTF gene results in motor neuron degeneration. Nature 365 (1993) 27-32
46. DeChiara T.M., Vejsada R., Poueymirou W.T., Acheson A., Suri C., Conover J.C., et al. Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83 (1995) 313-322