Proteasomal dysfunction induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidation: A mechanism contributing to neurodegeneration?

Journal of Neurochemistry

Volumn 83, Issue 2, 2002, Pages 360-370

  Hyun, Dong Hoon ^a   Lee, Moon Hee ^a   Halliwell, Barry ^b   Jenner, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

4 hydroxy 2,3, trans nonenal; Apoptosis; Oxidative stress; Proteasome

Indexed keywords

4 HYDROXYNONENAL; CARBONYL DERIVATIVE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; DNA FRAGMENT; PROTEASOME; SUPEROXIDE DISMUTASE; UBIQUITIN;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; ARTICLE; CELL METABOLISM; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION;

ALDEHYDES; APOPTOSIS; CASPASE 3; CASPASES; CELL MEMBRANE; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; LIPID PEROXIDATION; MULTIENZYME COMPLEXES; MUTATION; NEUROBLASTOMA; NEURODEGENERATIVE DISEASES; PROTEASOME ENDOPEPTIDASE COMPLEX; SUPEROXIDE DISMUTASE; TERATOCARCINOMA; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0036796753     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01125.x     Document Type: Article

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