-
1
-
-
19944428545
-
Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil
-
Aiba T, Shimizu W, Inagaki M, Noda T, Miyoshi S, Ding WG, Zankov DP, Toyoda F, Matsuura H, Horie M & Sunagawa K (2005). Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil. J Am Coll Cardiol 45, 300-307.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 300-307
-
-
Aiba, T.1
Shimizu, W.2
Inagaki, M.3
Noda, T.4
Miyoshi, S.5
Ding, W.G.6
Zankov, D.P.7
Toyoda, F.8
Matsuura, H.9
Horie, M.10
Sunagawa, K.11
-
2
-
-
0035903239
-
Action potential characteristics and arrhythmogenic properties of the cardiac conduction system of the murine heart
-
Anumonwo JM, Tallini YN, Vetter FJ & Jalife J (2001). Action potential characteristics and arrhythmogenic properties of the cardiac conduction system of the murine heart. Circ Res 89, 329-335.
-
(2001)
Circ Res
, vol.89
, pp. 329-335
-
-
Anumonwo, J.M.1
Tallini, Y.N.2
Vetter, F.J.3
Jalife, J.4
-
3
-
-
0032556030
-
+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice
-
+ current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice. Circ Res 83, 668-678.
-
(1998)
Circ Res
, vol.83
, pp. 668-678
-
-
Babij, P.1
Askew, G.R.2
Nieuwenhuijsen, B.3
Su, C.M.4
Bridal, T.R.5
Jow, B.6
Argentieri, T.M.7
Kulik, J.8
DeGennaro, L.J.9
Spinelli, W.10
Colatsky, T.J.11
-
4
-
-
0034599079
-
Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia
-
Baker LC, London B, Choi BR, Koren G & Salama G (2000). Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia. Circ Res 86, 396-407.
-
(2000)
Circ Res
, vol.86
, pp. 396-407
-
-
Baker, L.C.1
London, B.2
Choi, B.R.3
Koren, G.4
Salama, G.5
-
5
-
-
11944256461
-
Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts
-
Balasubramaniam R, Chawla S, Mackenzie L, Schwiening CJ, Grace AA & Huang CL (2004). Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts. Pflugers Arch 449, 150-158.
-
(2004)
Pflugers Arch
, vol.449
, pp. 150-158
-
-
Balasubramaniam, R.1
Chawla, S.2
Mackenzie, L.3
Schwiening, C.J.4
Grace, A.A.5
Huang, C.L.6
-
6
-
-
0142150032
-
Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1
-
Balasubramaniam R, Grace AA, Saumarez RC, Vandenberg JI & Huang CL (2003). Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1. J Physiol 552, 535-546.
-
(2003)
J Physiol
, vol.552
, pp. 535-546
-
-
Balasubramaniam, R.1
Grace, A.A.2
Saumarez, R.C.3
Vandenberg, J.I.4
Huang, C.L.5
-
7
-
-
4444302763
-
+ currents in adult mouse ventricles
-
+ currents in adult mouse ventricles. J Physiol 559, 103-120.
-
(2004)
J Physiol
, vol.559
, pp. 103-120
-
-
Brunet, S.1
Aimond, F.2
Li, H.3
Guo, W.4
Eldstrom, J.5
Fedida, D.6
Yamada, K.A.7
Nerbonne, J.M.8
-
8
-
-
0034822465
-
K,slow
-
K,slow. Am J Physiol Heart Circ Physiol 281, H1201-H1209.
-
(2001)
, vol.281
-
-
Brunner, M.1
Guo, W.2
Mitchell, G.F.3
Buckett, P.D.4
Nerbonne, J.M.5
Koren, G.6
-
9
-
-
0036200979
-
Ks in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations
-
Ks in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations. J Cardiovasc Electrophysiol 13, 172-177.
-
(2002)
, vol.13
, pp. 172-177
-
-
Burashnikov, A.1
Antzelevitch, C.2
-
10
-
-
0033916119
-
Congenital and acquired long QT syndrome
-
Camm AJ, Janse MJ, Roden DM, Rosen MR, Cinca J & Cobbe SM (2000). Congenital and acquired long QT syndrome. Eur Heart J 21, 1232-1237.
-
(2000)
Eur Heart J
, vol.21
, pp. 1232-1237
-
-
Camm, A.J.1
Janse, M.J.2
Roden, D.M.3
Rosen, M.R.4
Cinca, J.5
Cobbe, S.M.6
-
11
-
-
0035956935
-
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome
-
Casimiro MC, Knollmann BC, Ebert SN, Vary JC Jr, Greene AE, Franz MR, Grinberg A, Huang SP & Pfeifer K (2001). Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome. Proc Natl Acad Sci U S A 98, 2526-2531.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2526-2531
-
-
Casimiro, M.C.1
Knollmann, B.C.2
Ebert, S.N.3
Vary, J.C.4
Greene, A.E.5
Franz, M.R.6
Grinberg, A.7
Huang, S.P.8
Pfeifer, K.9
-
12
-
-
0032578771
-
Adult KCNE1 -knockout mice exhibit a mild cardiac cellular phenotype
-
Charpentier F, Merot J, Riochet D, Le Marec H & Escande D (1998). Adult KCNE1 -knockout mice exhibit a mild cardiac cellular phenotype. Biochem Biophys Res Commun 251, 806-810.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 806-810
-
-
Charpentier, F.1
Merot, J.2
Riochet, D.3
Le Marec, H.4
Escande, D.5
-
13
-
-
0032556025
-
Electrophysiological basis of arrhythmogenicity of QT/T alternans in the long-QT syndrome: Tridimensional analysis of the kinetics of cardiac repolarization
-
Chinushi M, Restivo M, Caref EB & El-Sherif N (1998). Electrophysiological basis of arrhythmogenicity of QT/T alternans in the long-QT syndrome: Tridimensional analysis of the kinetics of cardiac repolarization. Circ Res 83, 614-628.
-
(1998)
Circ Res
, vol.83
, pp. 614-628
-
-
Chinushi, M.1
Restivo, M.2
Caref, E.B.3
El-Sherif, N.4
-
14
-
-
0031752779
-
+ channels involved in long QT syndromes, are targets for calcium channel blockers
-
+ channels involved in long QT syndromes, are targets for calcium channel blockers. Mol Pharmacol 54, 695-703.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 695-703
-
-
Chouabe, C.1
Drici, M.D.2
Romey, G.3
Barhanin, J.4
Lazdunski, M.5
-
15
-
-
0025869640
-
Suppression of Torsades de Pointes with verapamil in patients with atrio-ventricular block
-
Cosio FG, Goicolea A, Lopez Gil M, Kallmeyer C & Barroso JL (1991). Suppression of Torsades de Pointes with verapamil in patients with atrio-ventricular block. Eur Heart J 12, 635-638.
-
(1991)
Eur Heart J
, vol.12
, pp. 635-638
-
-
Cosio, F.G.1
Goicolea, A.2
Lopez Gil, M.3
Kallmeyer, C.4
Barroso, J.L.5
-
16
-
-
26844506839
-
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
-
Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH & Bruneau BG (2005). The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 123, 347-358.
-
(2005)
Cell
, vol.123
, pp. 347-358
-
-
Costantini, D.L.1
Arruda, E.P.2
Agarwal, P.3
Kim, K.H.4
Zhu, Y.5
Zhu, W.6
Lebel, M.7
Cheng, C.W.8
Park, C.Y.9
Pierce, S.A.10
Guerchicoff, A.11
Pollevick, G.D.12
Chan, T.Y.13
Kabir, M.G.14
Cheng, S.H.15
Husain, M.16
Antzelevitch, C.17
Srivastava, D.18
Gross, G.J.19
Hui, C.C.20
Backx, P.H.21
Bruneau, B.G.22
more..
-
17
-
-
33645348259
-
Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall
-
Dilly KW, Rossow CF, Votaw VS, Meabon JS, Cabarrus JL & Santana LF (2006). Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall. J Physiol 572, 227-241.
-
(2006)
J Physiol
, vol.572
, pp. 227-241
-
-
Dilly, K.W.1
Rossow, C.F.2
Votaw, V.S.3
Meabon, J.S.4
Cabarrus, J.L.5
Santana, L.F.6
-
18
-
-
0032514164
-
+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome
-
+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome. Circ Res 83, 95-102.
-
(1998)
Circ Res
, vol.83
, pp. 95-102
-
-
Drici, M.D.1
Arrighi, I.2
Chouabe, C.3
Mann, J.R.4
Lazdunski, M.5
Romey, G.6
Barhanin, J.7
-
19
-
-
0031936234
-
Mutation of the gene for IsK associated with both Jervell and Lange-Nielsen and Romano-Ward forms of Long-QT syndrome
-
Duggal P, Vesely MR, Wattanasirichaigoon D, Villafane J, Kaushik V & Beggs AH (1998). Mutation of the gene for IsK associated with both Jervell and Lange-Nielsen and Romano-Ward forms of Long-QT syndrome. Circulation 97, 142-146.
-
(1998)
Circulation
, vol.97
, pp. 142-146
-
-
Duggal, P.1
Vesely, M.R.2
Wattanasirichaigoon, D.3
Villafane, J.4
Kaushik, V.5
Beggs, A.H.6
-
20
-
-
0029835964
-
The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns
-
El-Sherif N, Caref EB, Yin H & Restivo M (1996). The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns. Circ Res 79, 474-492.
-
(1996)
Circ Res
, vol.79
, pp. 474-492
-
-
El-Sherif, N.1
Caref, E.B.2
Yin, H.3
Restivo, M.4
-
21
-
-
0037255772
-
Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia
-
Fabritz L, Kirchhof P, Franz MR, Eckardt L, Monnig G, Milberg P, Breithardt G & Haverkamp W (2003 a). Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia. Basic Res Cardiol 98, 25-32.
-
(2003)
Basic Res Cardiol
, vol.98
, pp. 25-32
-
-
Fabritz, L.1
Kirchhof, P.2
Franz, M.R.3
Eckardt, L.4
Monnig, G.5
Milberg, P.6
Breithardt, G.7
Haverkamp, W.8
-
22
-
-
0037377248
-
Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice
-
Fabritz L, Kirchhof P, Franz MR, Nuyens D, Rossenbacker T, Ottenhof A, Haverkamp W, Breithardt G, Carmeliet E & Carmeliet P (2003 b). Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice. Cardiovasc Res 57, 1085-1093.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 1085-1093
-
-
Fabritz, L.1
Kirchhof, P.2
Franz, M.R.3
Nuyens, D.4
Rossenbacker, T.5
Ottenhof, A.6
Haverkamp, W.7
Breithardt, G.8
Carmeliet, E.9
Carmeliet, P.10
-
23
-
-
0028500822
-
Differential expression of Isk mRNAs in mouse tissue during development and pregnancy
-
Felipe A, Knittle TJ, Doyle KL, Snyders DJ & Tamkun MM (1994). Differential expression of Isk mRNAs in mouse tissue during development and pregnancy. Am J Physiol Cell Physiol 267, C700-C705.
-
(1994)
Am J Physiol Cell Physiol
, vol.267
-
-
Felipe, A.1
Knittle, T.J.2
Doyle, K.L.3
Snyders, D.J.4
Tamkun, M.M.5
-
24
-
-
0034705040
-
Preventing ventricular fibrillation by flattening cardiac restitution
-
Garfinkel A, Kim YH, Voroshilovsky O, Qu Z, Kil JR, Lee MH, Karagueuzian HS, Weiss JN & Chen PS (2000). Preventing ventricular fibrillation by flattening cardiac restitution. Proc Natl Acad Sci U S A 97, 6061-6066.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6061-6066
-
-
Garfinkel, A.1
Kim, Y.H.2
Voroshilovsky, O.3
Qu, Z.4
Kil, J.R.5
Lee, M.H.6
Karagueuzian, H.S.7
Weiss, J.N.8
Chen, P.S.9
-
25
-
-
0023874297
-
Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells
-
Hagiwara N, Irisawa H & Kameyama M (1988). Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells. J Physiol 395, 233-253.
-
(1988)
J Physiol
, vol.395
, pp. 233-253
-
-
Hagiwara, N.1
Irisawa, H.2
Kameyama, M.3
-
26
-
-
0035201784
-
Monophasic action potential recordings from intact mouse heart: Validation, regional heterogeneity, and relation to refractoriness
-
Knollmann BC, Katchman AN & Franz MR (2001). Monophasic action potential recordings from intact mouse heart: Validation, regional heterogeneity, and relation to refractoriness. J Cardiovasc Electrophysiol 12, 1286-1294.
-
(2001)
J Cardiovasc Electrophysiol
, vol.12
, pp. 1286-1294
-
-
Knollmann, B.C.1
Katchman, A.N.2
Franz, M.R.3
-
27
-
-
1642479864
-
A patient with LQTS in whom verapamil administration and permanent pacemaker implantation were useful for preventing torsade de pointes
-
Komiya N, Tanaka K, Doi Y, Fukae S, Nakao K, Isomoto S, Seto S & Yano K (2004). A patient with LQTS in whom verapamil administration and permanent pacemaker implantation were useful for preventing torsade de pointes. Pacing Clin Electrophysiol 27, 123-124.
-
(2004)
Pacing Clin Electrophysiol
, vol.27
, pp. 123-124
-
-
Komiya, N.1
Tanaka, K.2
Doi, Y.3
Fukae, S.4
Nakao, K.5
Isomoto, S.6
Seto, S.7
Yano, K.8
-
28
-
-
0033524661
-
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system
-
Kupershmidt S, Yang T, Anderson ME, Wessels A, Niswender KD, Magnuson MA & Roden DM (1999). Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ Res 84, 146-152.
-
(1999)
Circ Res
, vol.84
, pp. 146-152
-
-
Kupershmidt, S.1
Yang, T.2
Anderson, M.E.3
Wessels, A.4
Niswender, K.D.5
Magnuson, M.A.6
Roden, D.M.7
-
29
-
-
0034518479
-
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
-
Lee MP, Ravenel JD, Hu RJ, Lustig LR, Tomaselli G, Berger RD, Brandenburg SA, Litzi TJ, Bunton TE, Limb C, Francis H, Gorelikow M, Gu H, Washington K, Argani P, Goldenring JR, Coffey RJ & Feinberg AP (2000). Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J Clin Invest 106, 1447-1455.
-
(2000)
J Clin Invest
, vol.106
, pp. 1447-1455
-
-
Lee, M.P.1
Ravenel, J.D.2
Hu, R.J.3
Lustig, L.R.4
Tomaselli, G.5
Berger, R.D.6
Brandenburg, S.A.7
Litzi, T.J.8
Bunton, T.E.9
Limb, C.10
Francis, H.11
Gorelikow, M.12
Gu, H.13
Washington, K.14
Argani, P.15
Goldenring, J.R.16
Coffey, R.J.17
Feinberg, A.P.18
-
31
-
-
1542329703
-
In vivo temporal and spatial distribution of depolarization and repolarization and the illusive murine T wave
-
Liu G, Iden JB, Kovithavongs K, Gulamhusein R, Duff HJ & Kavanagh KM (2004). In vivo temporal and spatial distribution of depolarization and repolarization and the illusive murine T wave. J Physiol 555, 267-279.
-
(2004)
J Physiol
, vol.555
, pp. 267-279
-
-
Liu, G.1
Iden, J.B.2
Kovithavongs, K.3
Gulamhusein, R.4
Duff, H.J.5
Kavanagh, K.M.6
-
32
-
-
10044273431
-
Mouse models of cardiac arrhythmias
-
In D.P. Zipes and J. Jalife Elsevier Philadelphia
-
London B (2004). Mouse models of cardiac arrhythmias. In Cardiac Electrophysiology from Cell to Bedside, ed. Zipes DP & Jalife J, pp. 433-443. Elsevier, Philadelphia.
-
(2004)
Cardiac Electrophysiology from Cell to Bedside
, pp. 433-443
-
-
London, B.1
-
33
-
-
4244201143
-
QT interval prolongation and arrhythmias in heterozygous Merg1-targeted mice
-
Abstract
-
London B, Pan X-H, Lewarchik C & Lee C (1998). QT interval prolongation and arrhythmias in heterozygous Merg1-targeted mice. Circulation 98, I-56. (Abstract)
-
(1998)
Circulation
, vol.98
-
-
London, B.1
Pan, X.-H.2
Lewarchik, C.3
Lee, C.4
-
34
-
-
33747061856
-
Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome
-
Lu CW, Lin JH, Rajawat YS, Jerng H, Rami TG, Sanchez XV, Defreitas G, Carabello B, Demayo F, Kearney DL, Miller G, Li H, Pfaffinger PF, Bowles NE, Khoury DS & Towbin JA (2006). Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome. J Med Genet 43, 653-659.
-
(2006)
J Med Genet
, vol.43
, pp. 653-659
-
-
Lu, C.W.1
Lin, J.H.2
Rajawat, Y.S.3
Jerng, H.4
Rami, T.G.5
Sanchez, X.V.6
Defreitas, G.7
Carabello, B.8
Demayo, F.9
Kearney, D.L.10
Miller, G.11
Li, H.12
Pfaffinger, P.F.13
Bowles, N.E.14
Khoury, D.S.15
Towbin, J.A.16
-
35
-
-
0345871940
-
Implications of ventricular arrhythmia vulnerability during murine electrophysiology studies
-
Maguire CT, Wakimoto H, Patel VV, Hammer PE, Gauvreau K & Berul CI (2003). Implications of ventricular arrhythmia vulnerability during murine electrophysiology studies. Physiol Genomics 15, 84-91.
-
(2003)
Physiol Genomics
, vol.15
, pp. 84-91
-
-
Maguire, C.T.1
Wakimoto, H.2
Patel, V.V.3
Hammer, P.E.4
Gauvreau, K.5
Berul, C.I.6
-
36
-
-
22144484449
-
Verapamil prevents torsade de pointes by reduction of transmural dispersion of repolarization and suppression of early afterdepolarizations in an intact heart model of LQT3
-
Milberg P, Reinsch N, Osada N, Wasmer K, Monnig G, Stypmann J, Breithardt G, Haverkamp W & Eckardt L (2005). Verapamil prevents torsade de pointes by reduction of transmural dispersion of repolarization and suppression of early afterdepolarizations in an intact heart model of LQT3. Basic Res Cardiol 100, 365-371.
-
(2005)
Basic Res Cardiol
, vol.100
, pp. 365-371
-
-
Milberg, P.1
Reinsch, N.2
Osada, N.3
Wasmer, K.4
Monnig, G.5
Stypmann, J.6
Breithardt, G.7
Haverkamp, W.8
Eckardt, L.9
-
37
-
-
0242464931
-
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
-
Mohler PJ, Schott JJ, Gramolini AO, Dilly KW, Guatimosim S, duBell WH, Song LS, Haurogne K, Kyndt F, Ali ME, Rogers TB, Lederer WJ, Escande D, Le Marec H & Bennett V (2003). Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature 421, 634-639.
-
(2003)
Nature
, vol.421
, pp. 634-639
-
-
Mohler, P.J.1
Schott, J.J.2
Gramolini, A.O.3
Dilly, K.W.4
Guatimosim, S.5
duBell, W.H.6
Song, L.S.7
Haurogne, K.8
Kyndt, F.9
Ali, M.E.10
Rogers, T.B.11
Lederer, W.J.12
Escande, D.13
Le Marec, H.14
Bennett, V.15
-
38
-
-
0347753407
-
Transgenic models in cardiac arrhythmias: How close can we get to the bedside?
-
Napolitano C (2004). Transgenic models in cardiac arrhythmias: How close can we get to the bedside? Cardiovasc Res 61, 206-207.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 206-207
-
-
Napolitano, C.1
-
39
-
-
0036110488
-
Heterogeneous expression of voltage-gated potassium channels in the heart: Roles in normal excitation and arrhythmias
-
Nerbonne JM & Guo W (2002). Heterogeneous expression of voltage-gated potassium channels in the heart: Roles in normal excitation and arrhythmias. J Cardiovasc Electrophysiol 13, 406-409.
-
(2002)
J Cardiovasc Electrophysiol
, vol.13
, pp. 406-409
-
-
Nerbonne, J.M.1
Guo, W.2
-
40
-
-
0035940747
-
+ channel function in mice: What have we learned, and where do we go from here?
-
+ channel function in mice: What have we learned, and where do we go from here?Circ Res 89, 944-956.
-
(2001)
, vol.89
, pp. 944-956
-
-
Nerbonne, J.M.1
Nichols, C.G.2
Schwarz, T.L.3
Escande, D.4
-
41
-
-
0034800266
-
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
-
Nuyens D, Stengl M, Dugarmaa S, Rossenbacker T, Compernolle V, Rudy Y, Smits JF, Flameng W, Clancy CE, Moons L, Vos MA, Dewerchin M, Benndorf K, Collen D, Carmeliet E & Carmeliet P (2001). Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med 7, 1021-1027.
-
(2001)
Nat Med
, vol.7
, pp. 1021-1027
-
-
Nuyens, D.1
Stengl, M.2
Dugarmaa, S.3
Rossenbacker, T.4
Compernolle, V.5
Rudy, Y.6
Smits, J.F.7
Flameng, W.8
Clancy, C.E.9
Moons, L.10
Vos, M.A.11
Dewerchin, M.12
Benndorf, K.13
Collen, D.14
Carmeliet, E.15
Carmeliet, P.16
-
42
-
-
26444440919
-
Transmural dispersion in LQT3 and arrhythmogenesis
-
Opthof T & Coronel R (2005). Transmural dispersion in LQT3 and arrhythmogenesis. Cardiovascular Res 68, 336-337.
-
(2005)
Cardiovascular Res
, vol.68
, pp. 336-337
-
-
Opthof, T.1
Coronel, R.2
-
43
-
-
0007410805
-
Effect of amlodipine on morbidity and mortality in severe chronic heart failure
-
Prospective Randomized Amlodipine Survival Evaluation Study Group
-
Packer M, O'Connor CM, Ghali JK, Pressler ML, Carson PE, Belkin RN, Miller AB, Neuberg GW, Frid D, Wertheimer JH, Cropp AB & DeMets DL (1996). Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group. N Engl J Med 335, 1107-1114.
-
(1996)
N Engl J Med
, vol.335
, pp. 1107-1114
-
-
Packer, M.1
O'Connor, C.M.2
Ghali, J.K.3
Pressler, M.L.4
Carson, P.E.5
Belkin, R.N.6
Miller, A.B.7
Neuberg, G.W.8
Frid, D.9
Wertheimer, J.H.10
Cropp, A.B.11
DeMets, D.L.12
-
44
-
-
0024539631
-
Frequency-related blocking of sodium channels in the membrane of isolated rat cardiomyocytes by the calcium antagonist verapamil
-
Pidoplichko VI & Verkhratskii AN (1989). [Frequency-related blocking of sodium channels in the membrane of isolated rat cardiomyocytes by the calcium antagonist verapamil]. Fiziol Zh 35, 87-89.
-
(1989)
Fiziol Zh
, vol.35
, pp. 87-89
-
-
Pidoplichko, V.I.1
Verkhratskii, A.N.2
-
45
-
-
1942441076
-
Role of calcium cycling versus restitution in the mechanism of repolarization alternans
-
Pruvot EJ, Katra RP, Rosenbaum DS & Laurita KR (2004). Role of calcium cycling versus restitution in the mechanism of repolarization alternans. Circ Res 94, 1083-1090.
-
(2004)
Circ Res
, vol.94
, pp. 1083-1090
-
-
Pruvot, E.J.1
Katra, R.P.2
Rosenbaum, D.S.3
Laurita, K.R.4
-
46
-
-
1842531830
-
Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome
-
Restivo M, Caref EB, Kozhevnikov DO & El-Sherif N (2004). Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome. J Cardiovasc Electrophysiol 15, 323-331.
-
(2004)
J Cardiovasc Electrophysiol
, vol.15
, pp. 323-331
-
-
Restivo, M.1
Caref, E.B.2
Kozhevnikov, D.O.3
El-Sherif, N.4
-
47
-
-
33745509567
-
Probing the arrhythmogenic substrate
-
Roden DM (2006). Probing the arrhythmogenic substrate. Heart Rhythm 3, 779-780.
-
(2006)
Heart Rhythm
, vol.3
, pp. 779-780
-
-
Roden, D.M.1
-
48
-
-
33747723381
-
The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion
-
Roepke TK, Anantharam A, Kirchhoff P, Busque SM, Young JB, Geibel JP, Lerner DJ & Abbott GW (2006). The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion. J Biol Chem 281, 23740-23747.
-
(2006)
J Biol Chem
, vol.281
, pp. 23740-23747
-
-
Roepke, T.K.1
Anantharam, A.2
Kirchhoff, P.3
Busque, S.M.4
Young, J.B.5
Geibel, J.P.6
Lerner, D.J.7
Abbott, G.W.8
-
49
-
-
0028069574
-
Electrical alternans and vulnerability to ventricular arrhythmias
-
Rosenbaum DS, Jackson LE, Smith JM, Garan H, Ruskin JN & Cohen RJ (1994). Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med 330, 235-241.
-
(1994)
N Engl J Med
, vol.330
, pp. 235-241
-
-
Rosenbaum, D.S.1
Jackson, L.E.2
Smith, J.M.3
Garan, H.4
Ruskin, J.N.5
Cohen, R.J.6
-
50
-
-
0029854263
-
Ks potassium channel
-
Ks potassium channel. Nature 384, 80-83.
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Zou, A.3
Shen, J.4
Spector, P.S.5
Atkinson, D.L.6
Keating, M.T.7
-
51
-
-
33745496303
-
Delayed paced ventricular activation in the long QT syndrome is associated with ventricular fibrillation
-
Saumarez RC, Pytkowski M, Sterlinski M, Hauer RN, Derksen R, Lowe MD, Szwed H, Huang CL, Ward DE, Camm AJ & Grace AA (2006). Delayed paced ventricular activation in the long QT syndrome is associated with ventricular fibrillation. Heart Rhythm 3, 771-778.
-
(2006)
Heart Rhythm
, vol.3
, pp. 771-778
-
-
Saumarez, R.C.1
Pytkowski, M.2
Sterlinski, M.3
Hauer, R.N.4
Derksen, R.5
Lowe, M.D.6
Szwed, H.7
Huang, C.L.8
Ward, D.E.9
Camm, A.J.10
Grace, A.A.11
-
52
-
-
0033596974
-
Cellular and ionic basis for T-wave alternans under long-QT conditions
-
Shimizu W & Antzelevitch C (1999). Cellular and ionic basis for T-wave alternans under long-QT conditions. Circulation 99, 1499-1507.
-
(1999)
Circulation
, vol.99
, pp. 1499-1507
-
-
Shimizu, W.1
Antzelevitch, C.2
-
53
-
-
0028839535
-
Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome
-
Shimizu W, Ohe T, Kurita T, Kawade M, Arakaki Y, Aihara N, Kamakura S, Kamiya T & Shimomura K (1995). Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome. J Am Coll Cardiol 26, 1299-1309.
-
(1995)
J Am Coll Cardiol
, vol.26
, pp. 1299-1309
-
-
Shimizu, W.1
Ohe, T.2
Kurita, T.3
Kawade, M.4
Arakaki, Y.5
Aihara, N.6
Kamakura, S.7
Kamiya, T.8
Shimomura, K.9
-
54
-
-
24744448000
-
Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve
-
Silva J & Rudy Y (2005). Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve. Circulation 112, 1384-1391.
-
(2005)
Circulation
, vol.112
, pp. 1384-1391
-
-
Silva, J.1
Rudy, Y.2
-
55
-
-
0030723260
-
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
-
Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC & Keating MT (1997). Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat Genet 17, 338-340.
-
(1997)
Nat Genet
, vol.17
, pp. 338-340
-
-
Splawski, I.1
Tristani-Firouzi, M.2
Lehmann, M.H.3
Sanguinetti, M.C.4
Keating, M.T.5
-
56
-
-
22144496096
-
Atrial fibrillation in KCNE1 -null mice
-
Temple J, Frias P, Rottman J, Yang T, Wu Y, Verheijck EE, Zhang W, Siprachanh C, Kanki H, Atkinson JB, King P, Anderson ME, Kupershmidt S & Roden DM (2005). Atrial fibrillation in KCNE1 -null mice. Circ Res 97, 62-69.
-
(2005)
Circ Res
, vol.97
, pp. 62-69
-
-
Temple, J.1
Frias, P.2
Rottman, J.3
Yang, T.4
Wu, Y.5
Verheijck, E.E.6
Zhang, W.7
Siprachanh, C.8
Kanki, H.9
Atkinson, J.B.10
King, P.11
Anderson, M.E.12
Kupershmidt, S.13
Roden, D.M.14
-
57
-
-
0034044306
-
Clinical trials update: OPTIME-CHF, PRAISE-2, ALL-HAT
-
Thackray S, Witte K, Clark AL & Cleland JG (2000). Clinical trials update: OPTIME-CHF, PRAISE-2, ALL-HAT. Eur J Heart Fail 2, 209-212.
-
(2000)
Eur J Heart Fail
, vol.2
, pp. 209-212
-
-
Thackray, S.1
Witte, K.2
Clark, A.L.3
Cleland, J.G.4
-
58
-
-
0042934080
-
Nicotine induces a long QT phenotype in Kcnq1-deficient mouse hearts
-
Tosaka T, Casimiro MC, Rong Q, Tella S, Oh M, Katchman AN, Pezzullo JC, Pfeifer K & Ebert SN (2003). Nicotine induces a long QT phenotype in Kcnq1-deficient mouse hearts. J Pharmacol Exp Ther 306, 980-987.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 980-987
-
-
Tosaka, T.1
Casimiro, M.C.2
Rong, Q.3
Tella, S.4
Oh, M.5
Katchman, A.N.6
Pezzullo, J.C.7
Pfeifer, K.8
Ebert, S.N.9
-
59
-
-
33644906392
-
L-type calcium channels
-
Triggle DJ (2006). L-type calcium channels. Curr Pharm Des 12, 443-457.
-
(2006)
Curr Pharm Des
, vol.12
, pp. 443-457
-
-
Triggle, D.J.1
-
61
-
-
0030461289
-
Inner ear defects induced by null mutation of the isk gene
-
Vetter DE, Mann JR, Wangemann P, Liu J, McLaughlin KJ, Lesage F, Marcus DC, Lazdunski M, Heinemann SF & Barhanin J (1996). Inner ear defects induced by null mutation of the isk gene. Neuron 17, 1251-1264.
-
(1996)
Neuron
, vol.17
, pp. 1251-1264
-
-
Vetter, D.E.1
Mann, J.R.2
Wangemann, P.3
Liu, J.4
McLaughlin, K.J.5
Lesage, F.6
Marcus, D.C.7
Lazdunski, M.8
Heinemann, S.F.9
Barhanin, J.10
-
62
-
-
0034077362
-
Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: Time to revise current concepts
-
Volders PG, Vos MA, Szabo B, Sipido KR, de Groot SH, Gorgels AP, Wellens HJ & Lazzara R (2000). Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: Time to revise current concepts. Cardiovasc Res 46, 376-392.
-
(2000)
Cardiovasc Res
, vol.46
, pp. 376-392
-
-
Volders, P.G.1
Vos, M.A.2
Szabo, B.3
Sipido, K.R.4
de Groot, S.H.5
Gorgels, A.P.6
Wellens, H.J.7
Lazzara, R.8
-
64
-
-
0036083683
-
The multifaceted phenotype of the knockout mouse for the KCNE1 potassium channel gene
-
Warth R & Barhanin J (2002). The multifaceted phenotype of the knockout mouse for the KCNE1 potassium channel gene. Am J Physiol Regul Integr Comp Physiol 282, R639-R648.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
-
-
Warth, R.1
Barhanin, J.2
-
65
-
-
33745000775
-
From pulsus to pulseless: The saga of cardiac alternans
-
Weiss JN, Karma A, Shiferaw Y, Chen PS, Garfinkel A & Qu Z (2006). From pulsus to pulseless: The saga of cardiac alternans. Circ Res 98, 1244-1253.
-
(2006)
Circ Res
, vol.98
, pp. 1244-1253
-
-
Weiss, J.N.1
Karma, A.2
Shiferaw, Y.3
Chen, P.S.4
Garfinkel, A.5
Qu, Z.6
-
66
-
-
0033215099
-
Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 α subunit
-
Xu H, Barry DM, Li H, Brunet S, Guo W & Nerbonne JM (1999 a). Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 α subunit. Circ Res 85, 623-633.
-
(1999)
Circ Res
, vol.85
, pp. 623-633
-
-
Xu, H.1
Barry, D.M.2
Li, H.3
Brunet, S.4
Guo, W.5
Nerbonne, J.M.6
-
68
-
-
0035849589
-
Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome: Direct evidence from intracellular recordings in the intact left ventricular wall
-
Yan GX, Wu Y, Liu T, Wang J, Marinchak RA & Kowey PR (2001). Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome: Direct evidence from intracellular recordings in the intact left ventricular wall. Circulation 103, 2851-2856.
-
(2001)
Circulation
, vol.103
, pp. 2851-2856
-
-
Yan, G.X.1
Wu, Y.2
Liu, T.3
Wang, J.4
Marinchak, R.A.5
Kowey, P.R.6
-
69
-
-
0032489853
-
i transients in murine ventricular myocytes
-
i transients in murine ventricular myocytes. Circ Res 82, 657-665.
-
(1998)
Circ Res
, vol.82
, pp. 657-665
-
-
Yao, A.1
Su, Z.2
Nonaka, A.3
Zubair, I.4
Lu, L.5
Philipson, K.D.6
Bridge, J.H.7
Barry, W.H.8
-
71
-
-
0028911903
-
Early afterdepolarizations in cardiac myocytes: Mechanism and rate dependence
-
Zeng J & Rudy Y (1995). Early afterdepolarizations in cardiac myocytes: Mechanism and rate dependence. Biophys J 68, 949-964.
-
(1995)
Biophys J
, vol.68
, pp. 949-964
-
-
Zeng, J.1
Rudy, Y.2
-
72
-
-
0033553504
-
Mechanism of block and identification of the verapamil binding domain to HERG potassium channels
-
Zhang S, Zhou Z, Gong Q, Makielski JC & January CT (1999). Mechanism of block and identification of the verapamil binding domain to HERG potassium channels. Circ Res 84, 989-998.
-
(1999)
Circ Res
, vol.84
, pp. 989-998
-
-
Zhang, S.1
Zhou, Z.2
Gong, Q.3
Makielski, J.C.4
January, C.T.5
|