Rapid combinatorial access to macrocyclic ansapeptoids and ansapeptides with natural-product-like core structures

Synthesis

Volumn , Issue 23, 2006, Pages 3997-4004

  De Greef, Michiel ^a   Abeln, Sahan ^a   Belkasmi, Khalid ^a   Dömling, Alexander ^b   Orru, Romano V A ^a   Wessjohann, Ludger A ^a,c  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b R and D Biopharmaceuticals   (Germany)

^c LEIBNIZ INSTITUTE OF PLANT BIOCHEMISTRY   (Germany)

Author keywords

Alkaloids; Ansa compounds; Cyclopeptides; Macrocycles; Multicomponent reaction; Natural product analogues; Planar chirality

Indexed keywords

RATE CONSTANTS; SALTS; STRUCTURE (COMPOSITION); SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

ALKALOIDS; ANSA COMPOUNDS; CYCLOPEPTIDES; MACROCYCLES; MULTICOMPONENT REACTION; NATURAL PRODUCT ANALOGUES; PLANAR CHIRALITY;

AMINO ACIDS;

AMMONIA; ANSAPEPTIDE DERIVATIVE; ANSAPEPTOID DERIVATIVE; CYCLOPEPTIDE; MACROCYCLIC COMPOUND; NATURAL PRODUCT; PEPTIDE DERIVATIVE; PEPTOID; SODIUM CHLORIDE;

ARTICLE; CHEMICAL REACTION; CHIRALITY; COMBINATORIAL CHEMISTRY; ETHERIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

EID: 33845647216     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-950335     Document Type: Article

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