메뉴 건너뛰기




Volumn 14, Issue 3, 2001, Pages 143-150

αvβ3 Integrin in angiogenesis and restenosis. Small molecules, peptides, peptidomimetics and antibodies are being developed as antagonists of angiogenic activity

Author keywords

[No Author keywords available]

Indexed keywords

3 [[[1 [3 (1H IMIDAZOL 2 YLAMINO)PROPYL] 1H INDAZOL 5 YL]CARBONYL]AMINO] N (MESITYLSULFONYL)ALANINE; ANTIBODY; CP 4632; CYCLOPEPTIDE; INTEGRIN; L 748415; SP 4632; UNCLASSIFIED DRUG;

EID: 0034953628     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (37)

References (121)
  • 2
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation and signaling in cell adhesion
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 6
    • 0026759309 scopus 로고
    • Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
    • (1992) Nature , vol.358 , pp. 690-692
    • Guan, J.L.1    Shalloway, D.2
  • 10
    • 0027096622 scopus 로고
    • Signal transduction by the platelet integrin alphaIIb/beta3: Induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells
    • (1992) Mol Biol Cell , vol.3 , pp. 989-998
    • Pelletier, A.J.1    Bodary, S.C.2    Levinson, A.D.3
  • 11
    • 0027397549 scopus 로고
    • Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium
    • (1992) J Cell Biol , vol.120 , pp. 1003-1010
    • Schwartz, M.A.1
  • 21
  • 27
    • 0025248597 scopus 로고
    • Cloning, primary structure and properties of a novel human integrin beta subunit
    • (1990) EMBO , vol.9 , pp. 1561-1568
    • Ramaswamy, H.1    Hemler, M.E.2
  • 31
    • 0005306564 scopus 로고
    • Human endothelial cells synthesize and express an Arg-Gly-Asp directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6471-6475
    • Cheresh, D.1
  • 32
    • 0028984231 scopus 로고
    • An anti-alpha v-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice
    • (1995) J Cell Sci , vol.108 , pp. 2825-2838
    • Mitjans, F.1    Sander, D.2    Adan, J.3
  • 43
    • 0026334978 scopus 로고
    • Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells
    • (1991) J Clin Invest , vol.88 , pp. 1924-1932
    • Gladson, C.L.1    Cheresh, D.A.2
  • 70
    • 0028855585 scopus 로고
    • The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro
    • (1995) J Clin Invest , vol.95 , pp. 713-724
    • Liaw, L.1    Skinner, M.P.2    Raines, E.W.3
  • 72
    • 0031456703 scopus 로고    scopus 로고
    • Selective alpha v beta 3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha v beta 3 and osteopontin expression during neointima formation
    • (1997) Cardiovasc Res , vol.36 , pp. 408-428
    • Srivatsa, S.S.1    Fitzapatrick, L.A.2    Tsao, P.W.3
  • 73
  • 74
    • 0028345255 scopus 로고
    • Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months
    • The EPIC Investigators
    • (1994) Lancet , vol.343 , pp. 881-886
    • Topol, E.J.1    Califf, R.M.2    Weisman, H.F.3
  • 84
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone
    • (1994) J Cell Biochem , vol.55 , pp. 273-286
    • Parfitt, A.M.1
  • 92
    • 0027997413 scopus 로고
    • Selective cognition of cyclic RGD peptides of NMR defined conformation by alpha IIb beta 3, alpha v beta 3 and alpha 5 beta 1_integrins
    • (1994) J Biol Chem , vol.269 , pp. 20233-20238
    • Pfaff, M.1    Tangemann, K.2    Muller, B.3
  • 99
    • 0033960562 scopus 로고    scopus 로고
    • Integrins alpha v beta 3 and alpha v beta 5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide
    • (2000) Cancer Res , vol.60 , pp. 712-721
    • Erdreich-Epstein, A.1    Shimada, H.2    Groshen, S.3
  • 106
    • 0032080854 scopus 로고    scopus 로고
    • A peptidomimetic antagonist of the integrin alpha(v) beta 3 inhibits Leydig cell tumor growth and the development of hypercalcemia of malignancy
    • (1998) Cancer Res , vol.58 , pp. 1930-1935
    • Carron, C.P.1    Meyer, D.M.2    Pegg, J.A.3
  • 117
    • 0034650403 scopus 로고    scopus 로고
    • A specific sequence of the non-collagenous domain of the alpha v(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells
    • (2000) Cancer Res , vol.60 , pp. 467-473
    • Pasco, S.1    Han, J.2    Gillery, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.