Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration: Results of an in vitro and in vivo study

Life Sciences

Volumn 80, Issue 4, 2007, Pages 388-396

  Zheng, Fang ^a   Shi, Xiao Wen ^a   Yang, Gui Fang ^a   Gong, Ling Ling ^a   Yuan, Hong Yin ^a   Cui, Ye Jian ^a   Wang, Yan ^a   Du, Yu Min ^a   Li, Yan ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Chitosan nanoparticle; Gastrointestinal tract administration; Gene therapy; Plasmid DNA; Vector

Indexed keywords

CHITOSAN; GREEN FLUORESCENT PROTEIN; NANOPARTICLE; PLASMID DNA; QUATERNIZED CHITOSAN; TRIMETHYLATED CHITOSAN OLIGOMER;

ANIMAL EXPERIMENT; ARTICLE; BAGG ALBINO MOUSE; COACERVATION; COLON MUCOSA; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG STABILITY; DUODENUM; GASTROINTESTINAL MUCOSA; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ILEUM; INTESTINE MUCOSA; JEJUNUM; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUDE MOUSE; PROTEIN EXPRESSION; STOMACH MUCOSA;

ADMINISTRATION, ORAL; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHITOSAN; DNA; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GASTRIC MUCOSA; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; PLASMIDS; TRANSFECTION;

MUS MUSCULUS;

EID: 33845635731     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.09.040     Document Type: Article

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