Asymmetric synthesis of 2-(2-pyridyl)aziridines from 2-pyridineimines bearing stereogenic N-alkyl substituents and regioselective opening of the aziridine ring

Journal of Organic Chemistry

Volumn 71, Issue 25, 2006, Pages 9373-9381

  Savoia, Diego ^a   Alvaro, Giuseppe ^b   Di Fabio, Romano ^b   Gualandi, Andrea ^a   Fiorelli, Claudio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b GSK   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; AROMATIC COMPOUNDS; ETHERS; KETONES; LITHIUM COMPOUNDS; NITROGEN;

ALKYL SUBSTITUENTS; AZIRIDINES; NUCLEOPHILES; PYRIDINEIMINES;

AMINES;

2 (2 PYRIDYL)AZIRIDINE DERIVATIVE; 2 PYRIDINEIMINE DERIVATIVE; 3 PYRIDINEIMINE DERIVATIVE; 4 PYRIDINEIMINE DERIVATIVE; ALDEHYDE; ALPHA CHLOROKETONE; AZIRIDINE DERIVATIVE; BENZALDIMINE; CHLOROMETHYLLITHIUM; IMINE; KETONE; LITHIUM DERIVATIVE; NUCLEOPHILE; PYRIDINECARBOXALDEHYDE; VALINOL;

ADDITION REACTION; ARTICLE; ASYMMETRIC SYNTHESIS; AZIRIDINATION; CHELATION; PRODUCT RECOVERY; REACTION ANALYSIS; RING OPENING; STEREOCHEMISTRY; STEREOSPECIFICITY; SUBSTITUTION REACTION;

AZIRIDINES; IMINES; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM;

EID: 33845548948     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0614137     Document Type: Article

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