메뉴 건너뛰기




Volumn , Issue , 2004, Pages 255-266

Ionic Mechanisms of Cardiac Electrical Activity: A Theoretical Approach

Author keywords

[No Author keywords available]

Indexed keywords


EID: 33845498529     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B0-7216-0323-8/50031-2     Document Type: Chapter
Times cited : (3)

References (42)
  • 1
    • 2042481878 scopus 로고    scopus 로고
    • Models of cardiac ventricular action potentials: iterative interaction between experiment and simulation
    • Noble D, Rudy Y Models of cardiac ventricular action potentials: iterative interaction between experiment and simulation. Phil Trans Roy Soc (Lond) 2001, 359:1127-1142.
    • (2001) Phil Trans Roy Soc (Lond) , vol.359 , pp. 1127-1142
    • Noble, D.1    Rudy, Y.2
  • 3
    • 1642273778 scopus 로고    scopus 로고
    • The cardiac ventricular action potential
    • Oxford University Press, New York, E. Page, H.A. Fozzard, R.J. Solaro (Eds.)
    • Rudy Y The cardiac ventricular action potential. The Handbook of Physiology, section 2, vol 1, The Heart 2002, 531-547. Oxford University Press, New York. E. Page, H.A. Fozzard, R.J. Solaro (Eds.).
    • (2002) The Handbook of Physiology, section 2, vol 1, The Heart , pp. 531-547
    • Rudy, Y.1
  • 4
    • 0034026881 scopus 로고    scopus 로고
    • i overloaded cardiac myocytes: a simulation study
    • i overloaded cardiac myocytes: a simulation study. Biophys J 2000, 78:2392-2404.
    • (2000) Biophys J , vol.78 , pp. 2392-2404
    • Faber, G.M.1    Rudy, Y.2
  • 5
    • 0035201072 scopus 로고    scopus 로고
    • Ionic charge conservation and long-term steady state in the Luo-Rudy dynamic cell model
    • Hund TJ, Kucera JP, Otani NF, Rudy Y Ionic charge conservation and long-term steady state in the Luo-Rudy dynamic cell model. Biophys J 2001, 81:3324-3331.
    • (2001) Biophys J , vol.81 , pp. 3324-3331
    • Hund, T.J.1    Kucera, J.P.2    Otani, N.F.3    Rudy, Y.4
  • 6
    • 0029838677 scopus 로고    scopus 로고
    • Structure and function of voltage-dependent sodium channels: Comparison of brain II and cardiac isoforms
    • Fozzard HA, Hanck DA Structure and function of voltage-dependent sodium channels: Comparison of brain II and cardiac isoforms. Physiol Rev 1996, 76:887-926.
    • (1996) Physiol Rev , vol.76 , pp. 887-926
    • Fozzard, H.A.1    Hanck, D.A.2
  • 7
    • 0028899579 scopus 로고
    • 2+ current during release from sarcoplasmic reticulum in guinea pig ventricular myocytes
    • 2+ current during release from sarcoplasmic reticulum in guinea pig ventricular myocytes. Circ Res 1995, 76:102-109.
    • (1995) Circ Res , vol.76 , pp. 102-109
    • Sipido, K.R.1    Callewaert, G.2    Carmeliet, E.3
  • 8
    • 0029024749 scopus 로고
    • + current in ventricular myocytes of the guinea pig type: Theoretical formulation and their role in repolarization
    • + current in ventricular myocytes of the guinea pig type: Theoretical formulation and their role in repolarization. Circ Res 1995, 77:1-13.
    • (1995) Circ Res , vol.77 , pp. 1-13
    • Zeng, J.1    Laurita, K.R.2    Rosenbaum, D.S.3    Rudy, Y.4
  • 9
    • 0002270706 scopus 로고    scopus 로고
    • Electrical heterogeneity in the heart: Physiological, pharmacological and clinical implications
    • Oxford University Press, New York, E. Page, H.A. Fozzard, R.J. Solaro (Eds.)
    • Antzelevitch C, Dumaine R Electrical heterogeneity in the heart: Physiological, pharmacological and clinical implications. The Handbook of Physiology, section 2, vol 1, The Heart 2001, 654-692. Oxford University Press, New York. E. Page, H.A. Fozzard, R.J. Solaro (Eds.).
    • (2001) The Handbook of Physiology, section 2, vol 1, The Heart , pp. 654-692
    • Antzelevitch, C.1    Dumaine, R.2
  • 10
    • 0034012462 scopus 로고    scopus 로고
    • Profile and kinetics of L-type calcium current during the cardiac ventricular action potential compared in guinea-pigs, rats and rabbits
    • Linz KW, Meyer R Profile and kinetics of L-type calcium current during the cardiac ventricular action potential compared in guinea-pigs, rats and rabbits. Pflugers Arch 2000, 439:588-599.
    • (2000) Pflugers Arch , vol.439 , pp. 588-599
    • Linz, K.W.1    Meyer, R.2
  • 11
    • 0032801648 scopus 로고    scopus 로고
    • Sodium/calcium exchange: its physiological implications
    • Blaustein MP, Lederer WJ Sodium/calcium exchange: its physiological implications. Physiol Rev 1999, 79:763-854.
    • (1999) Physiol Rev , vol.79 , pp. 763-854
    • Blaustein, M.P.1    Lederer, W.J.2
  • 12
    • 0033635691 scopus 로고    scopus 로고
    • Determinants of excitability in cardiac myocytes: Mechanistic investigation of memory effect
    • Hund TJ, Rudy Y Determinants of excitability in cardiac myocytes: Mechanistic investigation of memory effect. Biophys J 2000, 79:3095-3104.
    • (2000) Biophys J , vol.79 , pp. 3095-3104
    • Hund, T.J.1    Rudy, Y.2
  • 13
    • 0033545725 scopus 로고    scopus 로고
    • Ks heterogeneity on action potential duration and its rate-dependence: A simulation study
    • Ks heterogeneity on action potential duration and its rate-dependence: A simulation study. Circulation 1999, 99:2466-2474.
    • (1999) Circulation , vol.99 , pp. 2466-2474
    • Viswanathan, P.C.1    Shaw, R.M.2    Rudy, Y.3
  • 14
    • 0035936798 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of cardiac arrhythmias
    • Keating MT, Sanguinetti MC Molecular and cellular mechanisms of cardiac arrhythmias. Cell 2001, 104:569-580.
    • (2001) Cell , vol.104 , pp. 569-580
    • Keating, M.T.1    Sanguinetti, M.C.2
  • 15
    • 0037049999 scopus 로고    scopus 로고
    • Cardiac channelopathies
    • Marban E Cardiac channelopathies. Nature 2002, 415:213-218.
    • (2002) Nature , vol.415 , pp. 213-218
    • Marban, E.1
  • 16
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to excitation and conduction in nerve
    • Hodgkin A, Huxley A A quantitative description of membrane current and its application to excitation and conduction in nerve. J Physiol (Lond) 1952, 117:500-544.
    • (1952) J Physiol (Lond) , vol.117 , pp. 500-544
    • Hodgkin, A.1    Huxley, A.2
  • 17
    • 0033527032 scopus 로고    scopus 로고
    • Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia
    • Clancy CE, Rudy Y Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature 1999, 400:566-569.
    • (1999) Nature , vol.400 , pp. 566-569
    • Clancy, C.E.1    Rudy, Y.2
  • 19
    • 0029097799 scopus 로고
    • Molecular mechanism for an inherited cardiac arrhythmia
    • Bennett PB, Yazawa K, Makita N, George AL Molecular mechanism for an inherited cardiac arrhythmia. Nature 1995, 376:683-685.
    • (1995) Nature , vol.376 , pp. 683-685
    • Bennett, P.B.1    Yazawa, K.2    Makita, N.3    George, A.L.4
  • 21
    • 0030968494 scopus 로고    scopus 로고
    • Pharmacological targeting of long QT mutant sodium channels
    • Wang DW, Yazawa K, Makita N, et al. Pharmacological targeting of long QT mutant sodium channels. J Clin Invest 1997, 99:1714-1720.
    • (1997) J Clin Invest , vol.99 , pp. 1714-1720
    • Wang, D.W.1    Yazawa, K.2    Makita, N.3
  • 23
    • 2442673477 scopus 로고    scopus 로고
    • Automaticity and triggered activity
    • Marcel Dekker, New York, P.M. Spooner, M.R. Rosen (Eds.)
    • Vos MA, Lerman BB Automaticity and triggered activity. Foundations of Cardiac Arrhythmias 2001, 425-447. Marcel Dekker, New York. P.M. Spooner, M.R. Rosen (Eds.).
    • (2001) Foundations of Cardiac Arrhythmias , pp. 425-447
    • Vos, M.A.1    Lerman, B.B.2
  • 24
    • 0028911903 scopus 로고
    • Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence
    • Zeng J, Rudy Y Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J 1995, 63:949-964.
    • (1995) Biophys J , vol.63 , pp. 949-964
    • Zeng, J.1    Rudy, Y.2
  • 25
    • 0032979304 scopus 로고    scopus 로고
    • Pause induced early afterdepolarizations in the long QT syndrome: A simulation study
    • Viswanathan PC, Rudy Y Pause induced early afterdepolarizations in the long QT syndrome: A simulation study. Cardiovasc Res 1999, 42:530-542.
    • (1999) Cardiovasc Res , vol.42 , pp. 530-542
    • Viswanathan, P.C.1    Rudy, Y.2
  • 26
    • 0035028582 scopus 로고    scopus 로고
    • Cellular consequences of HERG mutations in the long QT syndrome: Precursors to sudden cardiac death
    • Clancy CE, Rudy Y Cellular consequences of HERG mutations in the long QT syndrome: Precursors to sudden cardiac death. Cardiovasc Res 2001, 50:301-313.
    • (2001) Cardiovasc Res , vol.50 , pp. 301-313
    • Clancy, C.E.1    Rudy, Y.2
  • 27
    • 0037066036 scopus 로고    scopus 로고
    • + channel mutation that causes both Brugada and long QT syndrome phenotypes: A simulation study of mechanism
    • + channel mutation that causes both Brugada and long QT syndrome phenotypes: A simulation study of mechanism. Circulation 2002, 105:1208-1213.
    • (2002) Circulation , vol.105 , pp. 1208-1213
    • Clancy, C.E.1    Rudy, Y.2
  • 28
    • 0033533990 scopus 로고    scopus 로고
    • A single Na(+) channel mutation causing both long-QT and Brugada syndromes
    • Bezzina C, Veldkamp MW, van den Berg MP, et al. A single Na(+) channel mutation causing both long-QT and Brugada syndromes. Circ Res 1999, 85:1206-1213.
    • (1999) Circ Res , vol.85 , pp. 1206-1213
    • Bezzina, C.1    Veldkamp, M.W.2    van den Berg, M.P.3
  • 29
    • 0034640093 scopus 로고    scopus 로고
    • Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel
    • Veldkamp MW, Viswanathan PC, Bezzina C, et al. Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel. Circ Res 2000, 86:E91-E97.
    • (2000) Circ Res , vol.86
    • Veldkamp, M.W.1    Viswanathan, P.C.2    Bezzina, C.3
  • 30
    • 0030665763 scopus 로고    scopus 로고
    • Ionic mechanisms of propagation in cardiac tissue. Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling
    • Shaw RM, Rudy Y Ionic mechanisms of propagation in cardiac tissue. Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ Res 1997, 81:727-741.
    • (1997) Circ Res , vol.81 , pp. 727-741
    • Shaw, R.M.1    Rudy, Y.2
  • 31
    • 0034051941 scopus 로고    scopus 로고
    • Action potential propagation in inhomogeneous cardiac tissue: Safety factor considerations and ionic mechanism
    • Wang Y, Rudy Y Action potential propagation in inhomogeneous cardiac tissue: Safety factor considerations and ionic mechanism. Am J Physiol 2000, 278:H1019-H1029.
    • (2000) Am J Physiol , vol.278
    • Wang, Y.1    Rudy, Y.2
  • 32
    • 0035955759 scopus 로고    scopus 로고
    • Mechanistic insights into very slow conduction in branching cardiac tissue: a model study
    • Kucera JP, Rudy Y Mechanistic insights into very slow conduction in branching cardiac tissue: a model study. Circ Res 2001, 82:799-806.
    • (2001) Circ Res , vol.82 , pp. 799-806
    • Kucera, J.P.1    Rudy, Y.2
  • 33
    • 0031021775 scopus 로고    scopus 로고
    • Involvement of the calcium inward current in cardiac impulse propagation: Induction of unidirectional conduction block by nifedipine and reversal by Bay K 8644
    • Rohr S, Kucera J Involvement of the calcium inward current in cardiac impulse propagation: Induction of unidirectional conduction block by nifedipine and reversal by Bay K 8644. Biophys J 1997, 72:754-766.
    • (1997) Biophys J , vol.72 , pp. 754-766
    • Rohr, S.1    Kucera, J.2
  • 34
    • 0028798092 scopus 로고
    • Calcium currents of ventricular cell pairs during action potential conduction
    • Kumar R, Joyner RW Calcium currents of ventricular cell pairs during action potential conduction. Am J Physiol 1995, 268:H2476-H2486.
    • (1995) Am J Physiol , vol.268
    • Kumar, R.1    Joyner, R.W.2
  • 35
    • 0030022461 scopus 로고    scopus 로고
    • Optical mapping in a new Guinea pig model of ventricular tachycardia reveals mechanisms for multiple wavelengths in a single reentrant circuit
    • Girouard SD, Pastore JM, Laurita KR, et al. Optical mapping in a new Guinea pig model of ventricular tachycardia reveals mechanisms for multiple wavelengths in a single reentrant circuit. Circulation 1996, 93:603-613.
    • (1996) Circulation , vol.93 , pp. 603-613
    • Girouard, S.D.1    Pastore, J.M.2    Laurita, K.R.3
  • 36
    • 0342506483 scopus 로고    scopus 로고
    • Role of wavefront curvature in propagation of cardiac impulse
    • Fast VG, Kléber AG Role of wavefront curvature in propagation of cardiac impulse. Cardiovasc Res 1996, 33:258-271.
    • (1996) Cardiovasc Res , vol.33 , pp. 258-271
    • Fast, V.G.1    Kléber, A.G.2
  • 37
    • 0000566378 scopus 로고    scopus 로고
    • Normal and abnormal conduction in the heart
    • Oxford University Press, New York, E. Page, H.A. Fozzard, R.J. Solaro (Eds.)
    • Kléber AG, Janse MJ, Fast VG Normal and abnormal conduction in the heart. The Handbook of Physiology, section 2, vol 1, The Heart 2002, 455-530. Oxford University Press, New York. E. Page, H.A. Fozzard, R.J. Solaro (Eds.).
    • (2002) The Handbook of Physiology, section 2, vol 1, The Heart , pp. 455-530
    • Kléber, A.G.1    Janse, M.J.2    Fast, V.G.3
  • 38
    • 0037013175 scopus 로고    scopus 로고
    • Ionic current basis of electrocardiographic waveforms: A model study
    • Gima K, Rudy Y Ionic current basis of electrocardiographic waveforms: A model study. Circ Res 2002, 90:889-896.
    • (2002) Circ Res , vol.90 , pp. 889-896
    • Gima, K.1    Rudy, Y.2
  • 39
    • 0032480801 scopus 로고    scopus 로고
    • Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome
    • Yan GX, Antzelevitch C Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation 1998, 98:1928-1936.
    • (1998) Circulation , vol.98 , pp. 1928-1936
    • Yan, G.X.1    Antzelevitch, C.2
  • 40
    • 0033368409 scopus 로고    scopus 로고
    • Cellular basis for long-QT, transmural dispersion of repolarization, and torsade de pointes in the long-QT syndrome
    • Shimizu W, Antzelevitch C Cellular basis for long-QT, transmural dispersion of repolarization, and torsade de pointes in the long-QT syndrome. J Electrocardiol 1999, 32(suppl):177-184.
    • (1999) J Electrocardiol , vol.32 , Issue.SUPPL. , pp. 177-184
    • Shimizu, W.1    Antzelevitch, C.2
  • 42
    • 0032741905 scopus 로고    scopus 로고
    • Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent
    • Dumaine R, Towbin JA, Brugada P, et al. Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent. Circ Res 1999, 83:803-809.
    • (1999) Circ Res , vol.83 , pp. 803-809
    • Dumaine, R.1    Towbin, J.A.2    Brugada, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.